Lcom033296.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Leucania comma
Gene Symbol
-
Assembly
GCA_958295575.1
Location
OY282487.1:1643514-1646493[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 17 0.0078 0.84 11.4 0.5 1 23 244 267 244 267 0.94
2 17 8.5e-05 0.0091 17.6 5.9 1 23 272 294 272 294 0.99
3 17 6.4 6.8e+02 2.2 0.1 3 23 299 319 298 319 0.84
4 17 0.024 2.6 9.8 0.8 1 23 324 347 324 347 0.96
5 17 0.0011 0.11 14.1 0.8 2 23 408 430 407 430 0.96
6 17 0.00064 0.068 14.8 1.8 1 23 436 459 436 459 0.96
7 17 0.002 0.21 13.2 0.7 3 21 464 482 462 483 0.94
8 17 0.0031 0.33 12.6 1.1 1 23 491 514 491 514 0.91
9 17 0.045 4.8 9.0 0.3 2 23 555 576 554 576 0.94
10 17 0.00057 0.061 14.9 2.2 1 23 582 604 582 604 0.97
11 17 0.0057 0.6 11.8 2.7 1 23 640 662 640 662 0.96
12 17 0.025 2.7 9.8 0.2 2 23 667 688 666 688 0.93
13 17 0.00051 0.055 15.1 1.2 2 23 720 742 719 742 0.96
14 17 0.00067 0.071 14.7 1.4 1 23 748 770 748 770 0.98
15 17 0.0022 0.24 13.1 4.1 2 23 777 798 776 798 0.96
16 17 1.9e-05 0.0021 19.6 1.3 1 23 804 827 804 827 0.97
17 17 1.4 1.5e+02 4.3 4.0 3 23 834 855 832 855 0.95

Sequence Information

Coding Sequence
ATGGAGGAAGCAGTGCTTAATGTCAATCAAACAGATCCAAAGCATTTGGAATGGATAAAACAAAAACTCAAGACCGTATGGACGTGTCCCACATTCTGCGGGCTGTGCCTTGATGGCTTCAGCAACTTCTGTTCCGTTGACATGGAGCTTGTTATCAGCCATCAGACACTCTCCAAATGTCTGCGGGATATACTCAACTATGTGTTTAATGATGATgttGAAAATTTCATGTCAAGTCCAAACTTATGTGACAGTTGTACAGAGAAAACAATACAAGCTTACCTATTTATACACAATGCAAAACAGCTGAACAAAATCATAACCAACTGCATTTCAGATCTCGACTCCAAAGTAATTGACATCAACACTCAACTCGATGATTCCATAACATACGATACAGCCAATGTCATGATTGTCTTGGAAAATGATACCGAACTATACAAGACTATCATCGATGTCAAGTCTATGACTGAAGTTGTGCCCACCGCTAAACCTATTGCTATGAAAGATCCAGTAATTCCTAAACCGGAACCAAAAGTTGTTCAGGTTGCCAAACCTGTTAAACCGATAGTAATAAAAAGGGAAATAGAAAAACCTAAAGAAGTGAAACAagtcaaagaaagaaaaattgtaaaagctGATGGAACTCCAAACATTAGTTTGAAAGAAGGTCATATTGTTATCAAGCCATTGAGTTCCGTAAGAACCTCAGCCCCTCGATACAACACATATGAATGCACCGAATGTCCAGATATATTCACCACCTATAGATCATTGAAAGAACATGAAAAAGCCAAGCATAAAAAGTCTGTTTACCGATGCAAGCTCTGTGACAAAACTTACAACACACAGCAATATTTGTGCATACATTATAAGACACATTCCCGGGCTAGATGTAAGTTGTGCCAAGTTATACTACCAGAAGAGGAATTAATGGAGCATTTAAGGACAGTTCACCCTAATTTAGTGTACCCCTGCAAATTCTGTGATCTTGTCTACTACACCCAAGAATCTATGGacacacattttaaaataagccACTTAGTTAATGACACTAAAACGAAATCTCAATGTGTAATGTGTCTTAAGAACTTTGTGGATGCTGAAATGAAGAAGCACAAATGCAAGTTCTCATGCTCTGAATGTTTCGTTATGCCTTGCATTCACTTCAGATATCTAAATTCTTATAGAGAGCAAGTCTTAGGTcatgcaaataaaatacaatgctTGGATTGTGATTATGTTACTCGGCGCAAAGAACATCTCATTGGTCACACTAACAGAGAGCACTTGGACCATCATCCATTCACTTGTGCAGATTGTAACCAACAATTTTATACAAAGTTGAGTTTAAAAACACACATCATGCAGTTCCACGAGGATCTGTTCTGTCCACATTGTGACTTTGAATTCAAGGATAGCAGGACTTTAGTAACTCATAGGAAAGCCTGTAAGCTTGTGAAACGGCCATTCCAGTGTACCCACTGTGTGGCTTCATTTGACACTACTGAAGAGTTGACCAAACATGAAGCCTTGAAGCATAGTGAAGGAGTTCAGTCTTGCTCCCTTTGTAAAAGCAAATTCCTTACTGATATAGAACTGAAAGAACACCATGCCAGGGTTCACGGCGGTATACAATgcaagaaaagaagaaaacatATTGAATGCTCCTTATGTGACATAatgtttaaaaacattaaagaaATGCTTCAGCATGAAAAATTCCACAATGCAGATGAGGTTTACCCTTGTAAAGTGTGCTCAAAGAGCTTCAAATCATTAAGGAAACTATACATCCACAATCAAAGGCATTATACCGACAGAATAAAATGTTCCGGTTGTAATAAACGAGTAGCCGCTTCATTCTACCCTCAGCATGCAGTTAGGTGCCCTTACAAAAGAGATACTACTCTGAGCCATATCTGTGAAGTGTGCGGCAAGTCCTTCCACTTAGAATCATTGCTACGTTTCCATCAGAGAATCCACATGGAACCCCAACCATGCCCTCGATGCAATAAAGTTATCAAACCTACAAGTCTGAAAAGACATATGGAGCTAGTTCATGCAGAAGAAGAGGACAACGAGTGGACAGTCGGAACCACTACGGAAAACAAACCTAGGAAAATGAAAGGCATATCAAGCAAACCACCATCGATTGAGTGTGATATATGCGGACATGCAGTTAGGAAAAAATGTGATTTGGAAGCGCATATGAAcagatatcatttaaaaatcaagccATATGTCTGCTTTATATGCAATAAAGACTTTTGTGGTAAGGTCCGATTAAAAGAACATATAGCAACACACACAACTGACAACAGCTGTTTCTGTTCCGTTTGTGGAGGGAAATTTGCCAACCGTGTATGCCTTAAAATGCATATGAGAATGCATACTGGTGAAGCGCCTTATCCCTGTGATATATGCGGTCAGAGATTTAGGTCTTCTAGCATGATGAAAACACATAGACTAAAGAAACATTTGGAGAAAACTGTTTGCTGTCCACTTTGTGATAGTATGTTCTACATGGCCCGAGACATGAGGCATCATTTCAAGAAAACTCATTGGAAATTCAAAGATGGGAGGCCCTTCAATCCTAAAGATGTTGAAGAGTTACCTAAGGAGTGTTATTATCTTTTTGAAGATGGTCGACTGCCGAAAATTAATCGAGAATAG
Protein Sequence
MEEAVLNVNQTDPKHLEWIKQKLKTVWTCPTFCGLCLDGFSNFCSVDMELVISHQTLSKCLRDILNYVFNDDVENFMSSPNLCDSCTEKTIQAYLFIHNAKQLNKIITNCISDLDSKVIDINTQLDDSITYDTANVMIVLENDTELYKTIIDVKSMTEVVPTAKPIAMKDPVIPKPEPKVVQVAKPVKPIVIKREIEKPKEVKQVKERKIVKADGTPNISLKEGHIVIKPLSSVRTSAPRYNTYECTECPDIFTTYRSLKEHEKAKHKKSVYRCKLCDKTYNTQQYLCIHYKTHSRARCKLCQVILPEEELMEHLRTVHPNLVYPCKFCDLVYYTQESMDTHFKISHLVNDTKTKSQCVMCLKNFVDAEMKKHKCKFSCSECFVMPCIHFRYLNSYREQVLGHANKIQCLDCDYVTRRKEHLIGHTNREHLDHHPFTCADCNQQFYTKLSLKTHIMQFHEDLFCPHCDFEFKDSRTLVTHRKACKLVKRPFQCTHCVASFDTTEELTKHEALKHSEGVQSCSLCKSKFLTDIELKEHHARVHGGIQCKKRRKHIECSLCDIMFKNIKEMLQHEKFHNADEVYPCKVCSKSFKSLRKLYIHNQRHYTDRIKCSGCNKRVAASFYPQHAVRCPYKRDTTLSHICEVCGKSFHLESLLRFHQRIHMEPQPCPRCNKVIKPTSLKRHMELVHAEEEDNEWTVGTTTENKPRKMKGISSKPPSIECDICGHAVRKKCDLEAHMNRYHLKIKPYVCFICNKDFCGKVRLKEHIATHTTDNSCFCSVCGGKFANRVCLKMHMRMHTGEAPYPCDICGQRFRSSSMMKTHRLKKHLEKTVCCPLCDSMFYMARDMRHHFKKTHWKFKDGRPFNPKDVEELPKECYYLFEDGRLPKINRE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00039145;
90% Identity
iTF_01031398;
80% Identity
-