Ljuv000325.1
Basic Information
- Insect
- Leptidea juvernica
- Gene Symbol
- -
- Assembly
- GCA_949711685.1
- Location
- CATIXL010000001.1:8720699-8721381[-]
Transcription Factor Domain
- TF Family
- HMGA
- Domain
- HMGA domain
- PFAM
- AnimalTFDB
- TF Group
- Unclassified Structure
- Description
- This entry represents the HMGA family, whose members contain DNA-binding domains, also known as AT hooks due to their ability to interact with the narrow minor groove of AT-rich DNA sequences. They play an important role in chromatin organisation [1]. The high mobility group (HMG) proteins are the most abundant and ubiquitous nonhistone chromosomal proteins. They bind to DNA and to nucleosomes and are involved in the regulation of DNA-dependent processes such as transcription, replication, recombination, and DNA repair. They can be grouped into three families: HMGB (HMG 1/2), HMGN (HMG 14/17) and HMGA (HMG I/Y). The characteristic domains are: AT-hook for the HMGA family, the HMG Box for the HMGB family, and the nucleosome-binding domain (NBD) for the members of the HMGN family [2].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 4 0.0024 1e+02 3.9 1.8 11 16 13 18 11 20 0.83 2 4 0.14 6.1e+03 -1.7 3.8 12 15 33 36 31 49 0.63 3 4 3.1e-10 1.4e-05 25.9 2.8 4 21 53 70 51 71 0.90 4 4 0.12 5.2e+03 -1.5 4.6 10 15 83 88 82 89 0.83
Sequence Information
- Coding Sequence
- ATGTCTGATGATGGATCAACTGCAGTGGAGAAGAAAGGGCGAGGCAGACCCAAGGCAAATGGAACACAATCGGAATCAAAGGTTGATTCAAAAAAGCGTGGAAGGCCGGCAGTAGCACCAAAAGTCAAGGAATCCAAAAATTCATCAGATGATGAGCAAGCTCCAGCTACCAAAAGGGGTCGTGGCAGACCTAAGGGTTCCAAGAAGAAGGCGGCACCTAAGGCTAAGGGAGGATCAGGTGAATCCCGAGGACGTGGTAGACCACGCAAAGATGCTGCTCCATCCAAAAAAGATGCAGCTTCAACTGAAGAAGAACAGGAAGAAGATGAGGAAGAGGAAGAAGGCTCCGACCAGTAA
- Protein Sequence
- MSDDGSTAVEKKGRGRPKANGTQSESKVDSKKRGRPAVAPKVKESKNSSDDEQAPATKRGRGRPKGSKKKAAPKAKGGSGESRGRGRPRKDAAPSKKDAASTEEEQEEDEEEEEGSDQ
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00878866;
- 90% Identity
- iTF_00875322;
- 80% Identity
- iTF_00875322;