Lleu005192.1
Basic Information
- Insect
- Lasioglossum leucozonium
- Gene Symbol
- Rfx2
- Assembly
- GCA_028454225.1
- Location
- CM052218.1:6506538-6515414[+]
Transcription Factor Domain
- TF Family
- RFX
- Domain
- RFX domain
- PFAM
- PF02257
- TF Group
- Basic Domians group
- Description
- RFX is a regulatory factor which binds to the X box of MHC class II genes and is essential for their expression. The DNA-binding domain of RFX is the central domain of the protein and binds ssDNA as either a monomer or homodimer [1]. It recognize X-boxes (DNA of the sequence 5'-GTNRCC(0-3N)RGYAAC-3', where N is any nucleotide, R is a purine and Y is a pyrimidine) using a highly conserved 76-residue DNA-binding domain (DBD) [2].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 2 4.3e-11 2e-07 31.5 0.1 2 36 385 419 384 420 0.94 2 2 3.4e-09 1.5e-05 25.5 1.2 59 78 419 438 418 439 0.92
Sequence Information
- Coding Sequence
- ATGGACTGGTTGAAAAATGACGAGTACGGTCCCGTTTTATCCAAGAGATATTCCATAATGATGGCGGAGGAATCCTCGCTGCCAGTTATTTATTATCGGTCGCAAAATCCATTGACGAACCCTTCCCTCCAGAAGCGGACAGGTAGCGGTAGTAGTGAGATCTTGGGAGCAGAGAGAGGTGAAGGAGTGATTGCCATGACTACGACAGGAGCCCAGTATGCCCTCACAGCATCCGCCAGAGCCAATAATAGTGGGGGTAACTCTGCGACAGTGGGGGTGGAACCTAAGCCAAGCGTTGTTGTCGTGACTACTTCCAGTTCCAGTGGCAGTGGTAGTGCAGCGCAGAGTCAATCGACAAGGGGTCAGCAACTTATCACTGTTGTTACTAGTCCAGATCCTTCCAGTCCGAACAATCTGCAACCTATTCAGTTATTGGTTCAGGATCCGCTTGAAACAGCTGCAGATTCTTCCAACGGCTCAACAGGTACCCCAGCACATGTTACAGCGCAAGTTGTAGTGAACACTACTCACTCGGGTCAACACACTCTCGTCGATTCAGACGCTGCGTCTACATCGGCGGGCACAATCGTCAGCGGATCTCCACATTTCATTACCGTCACAGGCACCGGTGATTCACCATCCTACGCATCCCTCACAACGGCAGTAGTATCTGGTGAACCAGAGGCAGTGGGGTCCGAGTCAGTGTCTCATCCTACCTATGTTCAATATGTTGAGGGGGATGGTTCCACGTATATACCGACGAATGGACAGATGACATATCCTGTATACGCTGTTGGGGAAGCAGGGGCAATGTACACTCCTGCTTCGAGCCAATACTATACACCAGCATCCACACCTGTGACCTATGCACAGGTGACTGGGCAGGGTTCGAATTCGACGACTGGACAGTTATTATCTCAGGGCAATGGCACGTATTTGATCCAACAGAGTGTCGTGGATGGCGATCCAACCGCGCACGCGTTAATATCTGCAGCAGCTGCACGTGCCAGTCCACAAACGGAAAATGCGGAAACTGTGGTTAGCGGGGGTGGAGGGGCATACTTGATCAGCGGTAATTCAGGAGGTACTACAGTCACCGTGGAAGATGCTGCAGCTGCGGCAGCAAACATGACGCATGCTACTAGAGTTTCTCAAGCAACAGTTCACTGGTTGCTTGAAAATTATGAAACAGCGGATGGTGTCTCCCTGCCAAGATCTACGCTTTACAATCACTATCTACGCCATTGTTCTGAAAACAAACGACTAGGCACCAGAGGAAATTCAAAGTATCATTACTATGGGATTCGAGTGAAACCTAACTCTCCTTTGGTAATGTTGAACGAAGATGGAACGCCTCGCCAACAGCAAAGCGCCAACTCCCAAACGAAACGATTTAAATTTGTGAATCAAAAGCAGGAGACTACGTACGAGAACAACACTCACTCGAACACGAACATTTCTTCGAACACTTCGCCGCCGCAGTTCCATCAATACCTTGGCGAAGCGAGCGGCGCGATTCCAGAGTTTCCGGAAATAATAGTCAGCCATGGTTCCTCTCTGCCCGAAGACTGTACCTTAGAAGACATCGACACGTTTCGAAGTATATACAGAGAACATTGCGAGGCGTTCCTGGATGCTGTTCTCAATTTTGAATTTGCCACCGTGGAAAGTCTTTGGAGAGAATTTTGGCGTAGTCAGGACAATAATAATGGGGACGAGTGCGAGGAAGAGAAATATTTGTCAAAAACCAAACTGTATCAGATATGCAAGTGTTCGGAAGTTCAAGATTTCATTCAGAAAGTTGACTACACATTTTATCAGAACTTGGTCGAAGTATTAATGCCTAACGTATTGCGACCTATACCGAGCTCACTGACACAATCCATCCGAAACTTCGCAAAAGGTTTAGAGTCGTGGTTAACATCGGCGATGGCTGACTGTCCAGAAGAAATGACTCGGATAAAGTTGACAGCTGTGTCTGCATTTGCCCAAACATTAAGGCGTTACACGTCTCTGAACCACCTTGCTCAAGCAGCGCGCGCAGTGCTTCAAAATTCGAGTCAAATCAATCAAATGCTGGCGGATTTGAATCGTGTTGATTTTCATAATGTACAAGAACAGGCCTCTTGGGTTTGTCAATGCGATTATCGGATGGTCCAGCAATTAGAAGCAGATTTCAAAGTGACGCTACAGCAACAAAACTCATTGGAAGATTGGGCGATTTGGTTGAAGAGCGTCGTTACACAAGTTCTCAAACCGTTCGAGGAGAAACCTACGTTCGCGAAGGCTGCACGTCAATTTTTGCTCAAGTGGTCCTTCTACAGTTCCATGGTGATTCGTGATCTCACTTTAAGAAGCGCAGCTAGCTTTGGGTCTTTCCACTTGATCCGGTTACTATACGACGAGTACATGTTTTACTTGATCGAACATCAAGTAGCAATCGCTACGGGGACAACTCCGATAGCTGTAATGGGAGATAAAAGTCAAAATTGTTCTTTGCTCAGTGCATTTGGCGTGACTTCTAACGGAGATACTTTGAACACGAACCAACCAAAGCGCGTGAAACTAAGCTAA
- Protein Sequence
- MDWLKNDEYGPVLSKRYSIMMAEESSLPVIYYRSQNPLTNPSLQKRTGSGSSEILGAERGEGVIAMTTTGAQYALTASARANNSGGNSATVGVEPKPSVVVVTTSSSSGSGSAAQSQSTRGQQLITVVTSPDPSSPNNLQPIQLLVQDPLETAADSSNGSTGTPAHVTAQVVVNTTHSGQHTLVDSDAASTSAGTIVSGSPHFITVTGTGDSPSYASLTTAVVSGEPEAVGSESVSHPTYVQYVEGDGSTYIPTNGQMTYPVYAVGEAGAMYTPASSQYYTPASTPVTYAQVTGQGSNSTTGQLLSQGNGTYLIQQSVVDGDPTAHALISAAAARASPQTENAETVVSGGGGAYLISGNSGGTTVTVEDAAAAAANMTHATRVSQATVHWLLENYETADGVSLPRSTLYNHYLRHCSENKRLGTRGNSKYHYYGIRVKPNSPLVMLNEDGTPRQQQSANSQTKRFKFVNQKQETTYENNTHSNTNISSNTSPPQFHQYLGEASGAIPEFPEIIVSHGSSLPEDCTLEDIDTFRSIYREHCEAFLDAVLNFEFATVESLWREFWRSQDNNNGDECEEEKYLSKTKLYQICKCSEVQDFIQKVDYTFYQNLVEVLMPNVLRPIPSSLTQSIRNFAKGLESWLTSAMADCPEEMTRIKLTAVSAFAQTLRRYTSLNHLAQAARAVLQNSSQINQMLADLNRVDFHNVQEQASWVCQCDYRMVQQLEADFKVTLQQQNSLEDWAIWLKSVVTQVLKPFEEKPTFAKAARQFLLKWSFYSSMVIRDLTLRSAASFGSFHLIRLLYDEYMFYLIEHQVAIATGTTPIAVMGDKSQNCSLLSAFGVTSNGDTLNTNQPKRVKLS
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00254817;
- 90% Identity
- iTF_01418748;
- 80% Identity
- -