Hrec008777.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Hyppa rectilinea
Gene Symbol
sox2
Assembly
GCA_951799385.1
Location
OX637306.1:6638622-6639713[+]

Transcription Factor Domain

TF Family
HMG
Domain
HMG_box domain
PFAM
PF00505
TF Group
Other Alpha-Helix Group
Description
High mobility group (HMG) box domains are involved in binding DNA, and may be involved in protein-protein interactions as well. The structure of the HMG-box domain consists of three helices in an irregular array. HMG-box domains are found in one or more copies in HMG-box proteins, which form a large, diverse family involved in the regulation of DNA-dependent processes such as transcription, replication, and strand repair, all of which require the bending and unwinding of chromatin. Many of these proteins are regulators of gene expression. HMG-box proteins are found in a variety of eukaryotic organisms, and can be broadly divided into two groups, based on sequence-dependent and sequence-independent DNA recognition; the former usually contain one HMG-box motif, while the latter can contain multiple HMG-box motifs. HMG-box domains can be found in single or multiple copies in the following protein classes: HMG1 and HMG2 non-histone components of chromatin; SRY (sex determining region Y protein) involved in differential gonadogenesis; the SOX family of transcription factors [1]; sequence-specific LEF1 (lymphoid enhancer binding factor 1) and TCF-1 (T-cell factor 1) involved in regulation of organogenesis and thymocyte differentiation [2]; structure-specific recognition protein SSRP involved in transcription and replication; MTF1 mitochondrial transcription factor; nucleolar transcription factors UBF 1/2 (upstream binding factor) involved in transcription by RNA polymerase I; Abf2 yeast ARS-binding factor [3]; yeast transcription factors lxr1, Rox1, Nhp6b and Spp41; mating type proteins (MAT) involved in the sexual reproduction of fungi [4]; and the YABBY plant-specific transcription factors.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 1e-30 1.2e-27 97.0 2.4 1 69 89 157 89 157 0.99

Sequence Information

Coding Sequence
ATGTTGACGATGGAGACGGATCTCAAGGGCGGTAGCCTACATGCCACAGTGCCGCCGCATCACGCGCTCCAGCACGGCTACGGCTCGCTGGGCGCGCTCGGCGGTATGATGTCGCTGCCTCAGCAGCAACCCCTGTCGCAGCACCAGCCGCTGCAGCACCAGCACCACCAGTCCCTACCGCAGCACCACCAGCCCCAGCCACAACACCATCAACCGcccaacaacaacaataataataccagcaAAAACTCTAATGCAGAGCGTGTGAAGCGCCCCATGAACGCGTTCATGGTGTGGTCGCGCGGGCAACGCAGGAAGATGGCCTCTGACAACCCCAAAATGCATAACTCGGAAATATCGAAACGTCTCGGTGCACAGTGGAAAGACCTCTCTGAATCAGAGAAGCGACCGTTCATCGACGAGGCGAAGAGACTTCGCGCTGTTCACATGAAGGAACACCCGGATTACAAATACAGGCCGAGGAGGAAGACGAAGACCCTCGCCAAGAAACAAGAAAAGTACCCGCTAAGTGGAGGAGCATTGTTAGGTGGTGATGCACAGAGGAGCTCGGCACCGCCGTCGCAGCAGCCGCGTGACGTGTACCAAATGACACCGAACGGTTACATGCCCAACGGGTACATGATGCACGACCCCAGCGCCTACCAGCAGCAGGCGTACGGCTACCCGCGCTACGATGTGTCTCAGATGCAGCAGAGTGGCTACGGGCAGTACTACGGTGGCGGGCAGGGCTCGCCCTACCTGCCACAGCCGCCATCGCCCTCGGCGTACGGGCTGGGCCCCGGCTCGCCGGGCGGCTACGCGCTGCCCCCCTCGTGCGCCTCGCACTCGCCGAGCGGCTCCTCCGCCAAGTCCGAGCCGGTGTCCCCAGGCCCGCCGGGGCTGAAGCGCGAGTTCGGCCACGAGCCAGCGGTGCAGCTGAAGCGCGAGTTcgcgccgcacgcgcacgcACACGACATGGGCATGAAGCGCGAGTACGGGCAGCAGGAGCTGAGCCAGATCATCAACATGTACCACGTGCCCGACGAGCAGCGGTACGCAGCCGCCAACGAGCGCGCCATGCCGCTCATCTGA
Protein Sequence
MLTMETDLKGGSLHATVPPHHALQHGYGSLGALGGMMSLPQQQPLSQHQPLQHQHHQSLPQHHQPQPQHHQPPNNNNNNTSKNSNAERVKRPMNAFMVWSRGQRRKMASDNPKMHNSEISKRLGAQWKDLSESEKRPFIDEAKRLRAVHMKEHPDYKYRPRRKTKTLAKKQEKYPLSGGALLGGDAQRSSAPPSQQPRDVYQMTPNGYMPNGYMMHDPSAYQQQAYGYPRYDVSQMQQSGYGQYYGGGQGSPYLPQPPSPSAYGLGPGSPGGYALPPSCASHSPSGSSAKSEPVSPGPPGLKREFGHEPAVQLKREFAPHAHAHDMGMKREYGQQELSQIINMYHVPDEQRYAAANERAMPLI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00119580;
90% Identity
iTF_00072143; iTF_00810049; iTF_00809122; iTF_01487682; iTF_00018150; iTF_00001159; iTF_01361609; iTF_00017322; iTF_01538730; iTF_00274412; iTF_01377457; iTF_00273586; iTF_01362418; iTF_00177107; iTF_01285523; iTF_01363093; iTF_00327063; iTF_01425047; iTF_00237561; iTF_01342202; iTF_00000318; iTF_01029251; iTF_01026167; iTF_01027311; iTF_01028278; iTF_01031129; iTF_00888251; iTF_00973766; iTF_00851787; iTF_00850726; iTF_00771910; iTF_00300201; iTF_00951818; iTF_01230571; iTF_00186160; iTF_00185294; iTF_01119317; iTF_01338742; iTF_01340095; iTF_00049889; iTF_00375201; iTF_00449089; iTF_00036707; iTF_00038757; iTF_00364012; iTF_01526003; iTF_00374103; iTF_00907033; iTF_00906138; iTF_00907866; iTF_00785985; iTF_00785187; iTF_00783465; iTF_00383638; iTF_00784376; iTF_01063745; iTF_00711847; iTF_01064648; iTF_01061875; iTF_01062784; iTF_01532001; iTF_00446127; iTF_00685423; iTF_00447129; iTF_01533917; iTF_01533918; iTF_00040802; iTF_01094025; iTF_00758154; iTF_00122381; iTF_00039796; iTF_00121429; iTF_00667477; iTF_00042617; iTF_00924665; iTF_01093082; iTF_00043485; iTF_00071421; iTF_00124253; iTF_00041759; iTF_00123360; iTF_01030211; iTF_00037799; iTF_00301159; iTF_00726344; iTF_00172937; iTF_01533034; iTF_00302091; iTF_00445163; iTF_01527211; iTF_00928687; iTF_00450097; iTF_00745682; iTF_00147443; iTF_00120494; iTF_01441076; iTF_01439920; iTF_01246967; iTF_00425369; iTF_01084249; iTF_01085221; iTF_00622816; iTF_01534816; iTF_01118295; iTF_01117196; iTF_00111648; iTF_00171739;
80% Identity
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