Basic Information

Insect: Hyposoter dolosus
Gene Symbol: znf423
Assembly: GCA_963921915.1
Location: OY998132.1:10994348-11004886[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 22 1.5e-05 0.0014 19.1 1.5 1 23 97 119 97 119 0.97

2 22 0.2 19 6.1 4.9 1 23 125 147 125 147 0.98

3 22 1.1e-06 0.0001 22.7 4.1 1 23 153 175 153 175 0.99

4 22 0.00022 0.021 15.4 0.2 1 23 181 203 181 203 0.99

5 22 8.3 7.8e+02 1.0 0.3 3 23 279 301 277 301 0.79

6 22 0.013 1.2 9.9 0.1 1 23 366 389 366 389 0.97

7 22 0.25 24 5.8 0.0 2 23 400 422 399 422 0.88

8 22 0.2 19 6.1 0.1 3 23 492 512 491 512 0.97

9 22 0.0036 0.34 11.6 0.0 3 23 528 548 527 548 0.96

10 22 0.00056 0.053 14.1 1.4 1 23 557 580 557 580 0.93

11 22 2.3 2.2e+02 2.8 0.1 1 23 585 608 585 608 0.91

12 22 1.1 1e+02 3.8 2.2 2 23 678 699 678 699 0.96

13 22 0.0011 0.11 13.2 0.2 1 23 704 727 704 728 0.95

14 22 1.4 1.3e+02 3.5 0.1 2 23 796 819 795 819 0.88

15 22 0.00018 0.017 15.7 1.1 2 23 835 857 834 857 0.96

16 22 1.1 1e+02 3.8 0.6 1 12 866 877 866 889 0.76

17 22 3 2.8e+02 2.4 0.1 2 23 897 918 896 918 0.95

18 22 0.0084 0.8 10.4 0.1 1 23 1102 1125 1102 1125 0.90

19 22 0.14 14 6.6 0.4 1 23 1135 1158 1135 1158 0.95

20 22 4.2 3.9e+02 2.0 0.2 2 23 1171 1192 1170 1192 0.93

21 22 0.0041 0.39 11.4 1.1 2 23 1201 1223 1200 1223 0.94

22 22 0.13 12 6.7 1.4 1 23 1230 1253 1230 1253 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	22	1.5e-05	0.0014	19.1	1.5	1	23	97	119	97	119	0.97
2	22	0.2	19	6.1	4.9	1	23	125	147	125	147	0.98
3	22	1.1e-06	0.0001	22.7	4.1	1	23	153	175	153	175	0.99
4	22	0.00022	0.021	15.4	0.2	1	23	181	203	181	203	0.99
5	22	8.3	7.8e+02	1.0	0.3	3	23	279	301	277	301	0.79
6	22	0.013	1.2	9.9	0.1	1	23	366	389	366	389	0.97
7	22	0.25	24	5.8	0.0	2	23	400	422	399	422	0.88
8	22	0.2	19	6.1	0.1	3	23	492	512	491	512	0.97
9	22	0.0036	0.34	11.6	0.0	3	23	528	548	527	548	0.96
10	22	0.00056	0.053	14.1	1.4	1	23	557	580	557	580	0.93
11	22	2.3	2.2e+02	2.8	0.1	1	23	585	608	585	608	0.91
12	22	1.1	1e+02	3.8	2.2	2	23	678	699	678	699	0.96
13	22	0.0011	0.11	13.2	0.2	1	23	704	727	704	728	0.95
14	22	1.4	1.3e+02	3.5	0.1	2	23	796	819	795	819	0.88
15	22	0.00018	0.017	15.7	1.1	2	23	835	857	834	857	0.96
16	22	1.1	1e+02	3.8	0.6	1	12	866	877	866	889	0.76
17	22	3	2.8e+02	2.4	0.1	2	23	897	918	896	918	0.95
18	22	0.0084	0.8	10.4	0.1	1	23	1102	1125	1102	1125	0.90
19	22	0.14	14	6.6	0.4	1	23	1135	1158	1135	1158	0.95
20	22	4.2	3.9e+02	2.0	0.2	2	23	1171	1192	1170	1192	0.93
21	22	0.0041	0.39	11.4	1.1	2	23	1201	1223	1200	1223	0.94
22	22	0.13	12	6.7	1.4	1	23	1230	1253	1230	1253	0.96

Sequence Information

Coding Sequence: ATGCTTTTCAAAGGCAATAGTTCGCGATTGGAATTGCTGATTGGTAAGATCCAAGCTCACAAAGAATCACCGTCGCCACCTCGAGCTGATAAATGCAGCCCCAGAGCCAAAGATGCACTGGGTACCGGAAGTTCATCCTGGCACAGCGAAGATGGGGGAGCGAATTCGCGGCGCGGTGGGGAAACTCCATCGTCCTGCGCGACACCAACATCGGCGAGTTTTCCGTCGGAACCGGAAGTCGATTCAGAAATGGGTATCAGTGCCGATGGTAACAATCCCGCAGCACCTTATCCCTGCCAATTTTGTGACAGGACGTTTCCTCGACTCAGTTACTTGAAGAAACACGAGCAGAATCACGGCGATCAGATGCCCTATCGTTGCAGTTGGTGTTCGCGTTTGTTCAAGCACAAAAGGAGCAGAGATCGTCATGTGAAATTGCACACCGGTGATCGACGATACCGTTGTTCTCACTGCGAGGCTGCATTTTCCAGAAGCGATCATCTGAAGATTCACATGAAAACGCACGACAACCAAAAGCCTTATCAGTGTACAGCGTGCTCGCGAGGCTACAACACAGCTGCAGCGTTAACATCGCACATGCAGTCGCACAAGAAGCACCCGAGTCCGAATCAGGCAACCAAGATGGACTTGGATTACGGACGTCGAAGTGTGTCGTCTCATAGCACGACTTCACCGCCGATTCAGAATTCACCTTCTCCGAGTTTGAATCTCAGTATGAACGTCAAAAACGCGATGAAATCGCATCAATCGATTTATAACAACGGCGCGAGTGGAGCGAAAACTCCGATTATCAACTCGCCGCTGAAACTCGCTTGCATGTATTGTACGAAGGACTCTTTCACGAGTATGCAGCAGTTGCAGTTGCACGTTCAGGCGATGCATCAGGCGATCCTGAACGGCGGGAATTTGGACGTCGAATCGGCCGGCCACGTTAAATCAGAAGCGAACAACTCAAAGTGTCGTGACCGGATGACCGCGGACAGGAACGGTAGCAACGATAACCCGAGAACGTATCATTTCGAAGAACACGAAAAGTCCGTGGAAAGGGACAAAGGGAGCGCAGGAGAAAAGGGTTTTTCCTGTGGCCAGTGTACGATGAAGTTATCCGGGCTCAGCGAGCTGAGGGACCACATGGTGACGATCCATCGGAGCGAAAATTTAGGCTCGACTTTGATGATGTGTCCTCTGTGTGGAATCCCCTGTGCCTCAGCGGCCTCGTACGCGGAACACTACGTGCTCCAGCACTGCGAGAACCGACGCATGCCTTCGAAAGATTCGATTCATCGCGATTGGGAAAGTGTAAAGATAAACGGAAGCCACGAAAACAGTCGACCTGGTTCGGAGGATCGCGCCACCGCGAGCAGATCTGACCTCGGAACTTCGGGGCCTGCTGACTTGACGAAGAAACAATCGAGACCCAATGACACTGGCTACACAACGGGCACACTCCTTTGTGGACAGTGTGGAGCTGCCCTGAAGGACTTTGAATCATTCCGCGAACATCTCGCTCGCCATCTTCAGGCTGATCAACAAAGCAACGAGGTCTTACCCAGGAATCCATGTCCAAAATGTGGCGCAAGCTTCCCGGAACGGGAGGACATGCTGGTCCATTTAACGAAACATTATCTTGGCCAAGTGACGAAAGAGTACACGTGTGCTGCTTGCAAAAAGTGTTACCCTCATCCGGACCTCTTACAGCGGCATCTTCTAGACGCCCACGCTCATCATCTTTACCGATGTGCCGTTTGTCGCGACACGTTTGATTCCCGGGTAGCCATCCAGGTCCACTTCGCTGTCAAGCACAGCCAGGAAAGCCAAGTTTATCGTTGCAACGTTTGCATCAGTGAGACTTCACCTGGGAATTCGCCCAGCGAAGCCAGAAATTACTTCCGAACTGAAGCGGAAATGGCCAATCACGTCAGATCGGTCCATGCACCACCTTCCGTCGTCAACGAGAGTCCCCTGCGGCGCAGTCCGATTCCCACACCCGCTGCCACCTCGACCACTCCCCGATGCGTTTTTTGTGGCGTCTGCTGCAACACGGATCTAGAACTTCAACTCCATCTGGCTAGTCATTCGGCCAACTTGTATCGATGCCCTATTTGTAGGGAAGGCTTCCCGGTTGAGTTCCTGCTAGAGAGACACATAGCTCAATCCCATCACGCCATCAGTGACCGCAATGATTCCAGAGAAAATGGAAGAGCCTTCAGAGCTTCAAGGTCCCAAGATGAAACGACGAGATCCCAGAAGCGTGGACGATCACCAGCCTCGAGTAACAACAACTCCTTGAACCAATGTGACAACAATAACAAACGAGCGAATTACGGAGCGACCAATGGTACATCTCTGACATCGGGAGTCCAGCAATGCGAGCTTTGTGAGAGAGCGGAATTCGCGACGGAAGCAGAGCTTCAGGCGCACAAGAAATTGGTCCACACGCCGGTCAAGTTGCAAGCAAAGTCGTTGCCGTTGCTCAGTATGACTTGCGCCTACTGCGGAGAGGTTTGCCGTTCGCGAACTGATTTGGAGTCGCATACGAGGATCCAGCACGCTTCGAACGAGCCTGGTGGACGTCACAAGTGTAACATTTGCGACGAAGTCTGTCCGTCCGGTGGAATATTGGCGGAACACAAACTTCAGACGCACTGCAAAATCCAATTGAGCGATACTTGTGTCGTGTGTCGTGGCACTTTAGTCAATGAAGCTCAATTCATCGAACACGTTCAACGACACAGTTTGGAGAATGGTGACCCTCAGCAGCGATTGGACAACACGGTGCCTCTTTTACCTGCCGCCTGCGTCGTTTGCAGACAAACGTTGATCAGTGATTTGGAATGTCGCCTTCACGCCAGCCACCACTTGAGGAACTCCAATGTTTCGCAAATCACGAATTCCACTCCAAGTCCCAATCAGCATTCCAcccaacaacagcaacaacaacagcagcaacatcTCTTCCAATCAAACAGCTTGAGCTGTTGCTTGTGTCTGCGAGAATTCAGTGCCGATGACTTTGTCAGTTTACCATCGAATCCCGTTGGCACTGGAGGTCCGCCTTTGAGAGTTTGCAAACCCTGTTACGTTAGACACTCGCAAGGATTGCCCATACTCAATTCCCCTTATGAACACGTTAGAAAACCCAATACCGAACGAAGCAACTGGATCAATGCTAAGGATCCGACCAGCAGGGACACTTCCAGAGAACGGTGGGACATTGACAGATCCTTCAATGTCGGCGAAACCCATCAGAGTGCCAAAACAAGAATCACCGAGTCCGATGACTTCAGGTGCGATGAGTGCGGCATcaagtttgaaaattctgaCGAAGCTGACATTCACAGGGTTAAGGAACACGGAAAACTCTCAAGCAACTCTAATACTTACACCTGCATACAGTGCCAGATGTCCTTTccaactgaagaaaaaattcgacaacaCGTTCGTCAGGTCCATTTGGAATCACCCAGCAAGGCATCGCTGGATGCACTTCGTTGTCATCTTTGCGTTTTCGAAGCCAGCAGTCCTCTCCAGCTTCAGGGGCATTTGATCGAACACACTTTCGCAGGTTGTGCGGGCCTCACGTGTTACATTTGCCAGAGTCTCTTCACAACACCTCACGCTCTCCagAATCACATGCTCCAGCAACATGGACTCGGTGCGAGGCCGTACGACTGCAATAATTGcagcttgaaatttttcttccgcatCGAATTGGATCATCACGTGATGATGGCGCACCAAAGAAGCGAGGCGCCATCCCCCACGGTGGACGTCGGACAGGAAATGCCGACGGAAAATCAAACGAGGACGGAGCCAGAAGAGCACAGCAAGAAAGAGACGaaggataaaaattcagaggaCAATGGATCTGCGAAAAGGATTACGGTGAAAGAAGAAATCGTTCACAGtcccgaagaaaaagaattccaCATCGATGACGACGTCGAGCAAGATAATGACGAAGGAGCAAAAAGGGAGAAGTCGAATTTGTCGGATACGAAGACTGAAATGTTCAGCGTACAGCACGGAGAAGACCAGATGCAATCTTGA
Protein Sequence: MLFKGNSSRLELLIGKIQAHKESPSPPRADKCSPRAKDALGTGSSSWHSEDGGANSRRGGETPSSCATPTSASFPSEPEVDSEMGISADGNNPAAPYPCQFCDRTFPRLSYLKKHEQNHGDQMPYRCSWCSRLFKHKRSRDRHVKLHTGDRRYRCSHCEAAFSRSDHLKIHMKTHDNQKPYQCTACSRGYNTAAALTSHMQSHKKHPSPNQATKMDLDYGRRSVSSHSTTSPPIQNSPSPSLNLSMNVKNAMKSHQSIYNNGASGAKTPIINSPLKLACMYCTKDSFTSMQQLQLHVQAMHQAILNGGNLDVESAGHVKSEANNSKCRDRMTADRNGSNDNPRTYHFEEHEKSVERDKGSAGEKGFSCGQCTMKLSGLSELRDHMVTIHRSENLGSTLMMCPLCGIPCASAASYAEHYVLQHCENRRMPSKDSIHRDWESVKINGSHENSRPGSEDRATASRSDLGTSGPADLTKKQSRPNDTGYTTGTLLCGQCGAALKDFESFREHLARHLQADQQSNEVLPRNPCPKCGASFPEREDMLVHLTKHYLGQVTKEYTCAACKKCYPHPDLLQRHLLDAHAHHLYRCAVCRDTFDSRVAIQVHFAVKHSQESQVYRCNVCISETSPGNSPSEARNYFRTEAEMANHVRSVHAPPSVVNESPLRRSPIPTPAATSTTPRCVFCGVCCNTDLELQLHLASHSANLYRCPICREGFPVEFLLERHIAQSHHAISDRNDSRENGRAFRASRSQDETTRSQKRGRSPASSNNNSLNQCDNNNKRANYGATNGTSLTSGVQQCELCERAEFATEAELQAHKKLVHTPVKLQAKSLPLLSMTCAYCGEVCRSRTDLESHTRIQHASNEPGGRHKCNICDEVCPSGGILAEHKLQTHCKIQLSDTCVVCRGTLVNEAQFIEHVQRHSLENGDPQQRLDNTVPLLPAACVVCRQTLISDLECRLHASHHLRNSNVSQITNSTPSPNQHSTQQQQQQQQQHLFQSNSLSCCLCLREFSADDFVSLPSNPVGTGGPPLRVCKPCYVRHSQGLPILNSPYEHVRKPNTERSNWINAKDPTSRDTSRERWDIDRSFNVGETHQSAKTRITESDDFRCDECGIKFENSDEADIHRVKEHGKLSSNSNTYTCIQCQMSFPTEEKIRQHVRQVHLESPSKASLDALRCHLCVFEASSPLQLQGHLIEHTFAGCAGLTCYICQSLFTTPHALQNHMLQQHGLGARPYDCNNCSLKFFFRIELDHHVMMAHQRSEAPSPTVDVGQEMPTENQTRTEPEEHSKKETKDKNSEDNGSAKRITVKEEIVHSPEEKEFHIDDDVEQDNDEGAKREKSNLSDTKTEMFSVQHGEDQMQS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00439714; iTF_00263747; iTF_00265959; iTF_00266689; iTF_00829000; iTF_00262872; iTF_01299518; iTF_01509109;
90% Identity: iTF_00439714; iTF_00829000;
80% Identity: -