Hpro008293.1
Basic Information
- Insect
- Hypena proboscidalis
- Gene Symbol
- Rfx2
- Assembly
- GCA_905147285.1
- Location
- LR990129.1:21608209-21614278[+]
Transcription Factor Domain
- TF Family
- RFX
- Domain
- RFX domain
- PFAM
- PF02257
- TF Group
- Basic Domians group
- Description
- RFX is a regulatory factor which binds to the X box of MHC class II genes and is essential for their expression. The DNA-binding domain of RFX is the central domain of the protein and binds ssDNA as either a monomer or homodimer [1]. It recognize X-boxes (DNA of the sequence 5'-GTNRCC(0-3N)RGYAAC-3', where N is any nucleotide, R is a purine and Y is a pyrimidine) using a highly conserved 76-residue DNA-binding domain (DBD) [2].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 2 1.5e-33 2.9e-29 102.6 0.2 6 78 8 80 5 81 0.95 2 2 0.48 9.6e+03 -1.6 0.0 24 34 418 428 400 437 0.70
Sequence Information
- Coding Sequence
- ATGTATCTATATAGTTTACGAACGTTTTTACTCGACCTAAGTCGCGAGTGCGAGGGCGTTTCGCTTCCCCGCTCAACTCTATACTCTCACTACCTTCGTCACTGCGCCACACACCGGTTAGAACCGGTCAACGCCGCTTCTTTCGGGAAGCTCATCAGATCCGTGTTCGTGGGACTAAGGACTCGTCGCCTTGGTACACGAGGGAACTCCAAGTACCATTACTACGGCATCAGAGCTAAGCCGGGGATCGATGCGGACCATTCCGACGTGCGGGATGAAGGTCCTGAGCAACAGGAGAATGGAGATGACAGGACTGATGTTGTGGATCATCAGGAGGGCAGGCCTCGCGAACGTCCCCGTGCTACGAGTCCCACAGCTCACCAGCATCGTCAGTACTTGGGTGCAGTGGCTCCCCCTGAACCGCCCGCACTCACCATCGCTGACTTACCAGAGGATGTGCCTCATGATGCCGTCGATTCTCTCAGGAGACATCACAGGGAGCATGGCATAGAATTCCTGGAGGCCGTAGCAGCCCTGGACATCGTAGCAGTGGAGCGAGCTCGCCGTGCATTCTGGCGTCGTCCTCCGGAGGCGCTGTGCCGGCGCGTGCTGTGCCAGCTGACGTCCCGCCGCGACGTGGCGGCCTGGCTGCGGCTGGCCGAGCTGCAGCTGTACCAGCGCGCCGTGGAACTGCTGCTGCCCGATGTGCTACGACCTATCCCACCGCAGCTGACACAGTCGATCCGCAACTTCGCGAAGTGCCTCGAGGGCGCTCTGTCGGCGGGGGCGGGGGGCGcgcccgcggcggcggcgcgcgctCAAGCCGCTGCAGCGGCCGCGCTGGCTGCAGCGCTGCGCCGCTACACGTCGCTCAATCACCTCGCTCAGGCCGCCCGCGCGGTACTCACCAACCATCATCAGATACATCAGATGCTGGCGGACCTGAACCGCGTGGACTTCCGCGTGGTGCGCGAGCAGGCGGCGTGGGCGTGCTCGTGCGCCAGCGCCGCCACGGCGCACCGCCTCGAGGCCGACTTCAAGGCCACGCTCGGGCGCGGCGCGTCGCTGGAGCAGTGGGCGGGCTGGCTGGAGGCGTGCGTGCGCTCGGCGCTGGCCCCGCACGAGCGCCGCGCCGACTACTCCTCGCGCGCGCGGCGCCTGCTGCTCGACTGGTCCTTCTACTCCTCGCTCGTCATCCGCGAACTCACGCTCAGGTCGGCGGCGTCGTTCGGCTCCTTCCACCTCATCCGCCTGCTGTACGACGAGTACGTGTCGTACGTCATCGAGCGGCGCGTGGCGGCGCACCTCGCCGTGCCCGCCATCGCCGTCATGCCCAGGGTGCTCGAGCAGCCTGAAGAAGAGGAAGTACTGGAAGAGCCCATCCGCCAGGAACCTGACGAAGATGACCAGGATTGGGAGTGGGACGacgaggaagaagaagaagaagaacaacaaCCAGAGCCTAAGAGGATCAGACCTTCAGAGTAA
- Protein Sequence
- MYLYSLRTFLLDLSRECEGVSLPRSTLYSHYLRHCATHRLEPVNAASFGKLIRSVFVGLRTRRLGTRGNSKYHYYGIRAKPGIDADHSDVRDEGPEQQENGDDRTDVVDHQEGRPRERPRATSPTAHQHRQYLGAVAPPEPPALTIADLPEDVPHDAVDSLRRHHREHGIEFLEAVAALDIVAVERARRAFWRRPPEALCRRVLCQLTSRRDVAAWLRLAELQLYQRAVELLLPDVLRPIPPQLTQSIRNFAKCLEGALSAGAGGAPAAAARAQAAAAAALAAALRRYTSLNHLAQAARAVLTNHHQIHQMLADLNRVDFRVVREQAAWACSCASAATAHRLEADFKATLGRGASLEQWAGWLEACVRSALAPHERRADYSSRARRLLLDWSFYSSLVIRELTLRSAASFGSFHLIRLLYDEYVSYVIERRVAAHLAVPAIAVMPRVLEQPEEEEVLEEPIRQEPDEDDQDWEWDDEEEEEEEQQPEPKRIRPSE*
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00794035; iTF_00636004; iTF_00404422;
- 90% Identity
- -
- 80% Identity
- -