Basic Information

Insect: Hoplodrina blanda
Gene Symbol: baz-2
Assembly: GCA_949316365.1
Location: OX438573.1:5126115-5153585[-]

Transcription Factor Domain

TF Family: MBD
Domain: MBD domain
PFAM: PF01429
TF Group: Unclassified Structure
Description: The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 1.3e-12 3.8e-09 36.6 0.0 3 75 633 708 631 710 0.89

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	1.3e-12	3.8e-09	36.6	0.0	3	75	633	708	631	710	0.89

Sequence Information

Coding Sequence: ATGGACAAGGAAGGGGGGGATGGCGGCGACGCGGCGGGCAAGCAGCCCCCCGACGGCCTGCTCGATGCCGCTAACCTATTTGGTGCATACTGGGGTCGCGATGGCGGCGGCGGTGGGAGCGCGGCAGCGCAAGCGCAGGCGCAAGCACAAGCAGCCCTATTCGGCTTCGGGTCGCGCTACCCGCCCCCGACCACGCTCGGAGTGGCAGCCAATCAGGCAGCCTCTCTGGGGCTACATCCAGCTGCCAGCGCCGCCTGGTGGTCGATGGCATCACACCTAGCAGCTCAGGACTACCTGGCCAGGCTGCAGGCCTCAGGGTTAAACTTCCCACCGCTGGCCGACCCTTACGCCGCGCTCTCGGCCCTGTCCGGCGGCGGTGGGGGGTTGAAGCAGCCCCAGAAACCTGGGAAGTTGTCTAGTCGAAATGAGAGGTCAGGGAGAAGCAGTACATCATCAAGCGCCTCCACAAAAGACAAGAGTCCATCCACGAGCAGCGCAAATTCGCAGAACATGAGTGAGTGGGGGTCTTCATACGGTCTGCCGAAGACTTCGTCTCCGTCCGCGATGCACCACTCTGCGTCTCTGTCAAGCCTGGCTTCCCTCAACAGTCTGGTTTCTGCTCCTCATCAGAGCAAGTCCAGTAGCAAGCCCTCGGCCACGCCACAGCCTTCCAAAAAACcctcatcatcatcgtcatccaGTTCCAAAGGCAAGGAGCGCGAGCTAGCGTTGCTGCGCGGCGACCTGATGCTTGCGCAGGCGGCGGCGCACGGCGCGTACCACGCCGCCGTGGCTGCGGCTGCTAAGGGGAAGAACATGTCACCGCTGTACCCGTTTGGGATGCCAGGGACTGATAAGGATGGACGGCATGGCGGCATAGACTCCCTTACTGGCCTGCCGCATACTATACTCAGTGATCCATCATCAGTGCTGGGCGGTGTCAGATTGCCTCCGGATACTGAAATTATCAAGTATACCTCCTCGTTAGCCGGGCCCAAGTCAGGTGCGGGCACCACAACCCGCGGCCGTAAGAAGACGATCTCCCTCGACCCGCCGCACGTCAGCGTGCATCCCGCCGACCGGAACGCGCCGCTGCCCAGCAAACGGCCTAAACTTgacGAGTACGGCAACTCTCGGTCTTCGGTTGAGGTGATCCGACTGCCCAACAAACCGGACAGGCCCGGACACAACTCGATGTCCGGCACGCCCCCACCTAATCTCTCCGATTATGCAGGAATATCCCGAGAACTGCTGCAGACGATAGCTAGTCAGAGCGGCGTGAGCTTGGCCGCGCTGGAGCGTCAGCTGGCCGGCTCTACAGGTGACTATTATGCAGGTCTCAACCTAAGCACTAAGATGGGTGAAGACTCGCCTTTGGACCTAGGTGTCAAGTCTTCAGCAATGGATGACGATGCGCCACTAAACCTTTCACTGAAACCTACTCCTGCGAGTTCGCAAGCTTCAGATGCTCTCTCGCGACTGACGTCATTGAGCAGTTCGCTTAACGCCTCTTCCAGCCATGACAGGATATCTCGCCGCAAGCCCGGCGCGAAGCCTCGCCGCGTGGCGCCGGAGATGAACCCGGTGCCGGACGCGCCGCGACCCAAATCCAGCGGCAGCGAGGACAGTGAATCAGTAGCCGGGTGGGCAGGGCGCGAGGGCAGACCGCGCAATTTGGGCAGAGGAGTCAGCAAGCCCAAGAAGAACACTGTCGCGTCCTTATTGGCTCAGAGTCGAGCGCTGGGCTTGAGGCCTGCGCTTGCGCATCAGTTGTTAGCTGAGACTGACTTGGAAAAACTAAAAGCCTTGCTAGGCGAGACGGCGAGTACTGACTCGGAGTGTCCATCGGACAGCTGTCCGTCCGACTCGGACGCGTCCGATACCAGTCGGAGACCTAACGACGCGCAGCTTAGACTGCCTTTAGCTCTAGGTTGGAAACGCGTGACTGTGATCAAGGGTCTGTCCCGGAACTGCAGCATCAAAGGCGACGTGACGTACTCCCCGCCCGACCCGCATGCGGGCATCACCATGCGGTCGTTACATGACGTACAGAATttcCTAGACTCGAACCCATGTCCGCCGCTGTCGACGGACAACTTCAGCTTCTCTGCGCGCACAGTGCTCGGCGAGTACATCCAGCCGGCCAGCGATGTGGGGGAACCGCTTGTCTACAATGAGAGTGAGATTAATAAGAGGCTGGAAGAAGCCCGCCTCCTGGCGTCAGCGGGCGGGCGCCCCACCCCGCCCCCGCTGGACCGGCGCATGGAGCTGGCGCGCCTGCAGCAGGCCGCGCGGGACGCCAGGCGCGACGCCTCGCACCGCTCCAGGGACCAGGCCCGTCTCGAAAGATCAGAGAAAGCGGAACTAGCTAAACGCGAGAAAGAGGCGAGGAGTCAGCAGCTGTTAGAGCATATCAACAAGAATCGCACGCAGTTGACGATCGAGCCCCTCCCTACGGTACCGAAAACCGGTATCGACGAATGGAAAACACCCGAAATAGTGATGGGACCAGCCACTAAGACGAATAAGGAACGCATTATGCCTCCGATCAGTCTTTCGCTCATACCGGTCTCCGGCCCCAAAGACTCACAGAACTCcccaataaaaacaataaaattcgaCCAATCAGGATGGAAAGAGGAAATAGAGGAATACAACGCTTTAGACAAAATGAAAGACTTCGCTGAAAAAGCGGCTTTCGACCTCCCAAAACGAAAAGACAAACAATACGATTTCACATTAATAAAATCAGCAGAAAAGCGCTTGAAAGCGCCAGACAAAGAGAACAATCTAGAACGACTAATAGAATCGTACTCGAGAATAACAGAATTCATAAACGGCTGTGATTGGTCGAAACTGCAAGAGGATAAAAAAAGCGAAGACCCAAAGTCTATAGAGCAGAAATATTTAGACGCTAAAAATGAATTCATGTCCCAAAATTTAATGTTGATGCCAAAAGATAGTCCAAAATCTGTACTAAAAGATGTCATAGAACTAAGTGAGGACGATGATATACTGACAGATATTATGTCAAAGAAAATAAGTAAAGGGACGTTTAATGTGGGCAAAGACGGGGCCCTGTCTATCTCTGTACACCCCCTAGGCAAGGAGGCGACGTCATCGGTACGTGACACTCACTAA
Protein Sequence: MDKEGGDGGDAAGKQPPDGLLDAANLFGAYWGRDGGGGGSAAAQAQAQAQAALFGFGSRYPPPTTLGVAANQAASLGLHPAASAAWWSMASHLAAQDYLARLQASGLNFPPLADPYAALSALSGGGGGLKQPQKPGKLSSRNERSGRSSTSSSASTKDKSPSTSSANSQNMSEWGSSYGLPKTSSPSAMHHSASLSSLASLNSLVSAPHQSKSSSKPSATPQPSKKPSSSSSSSSKGKERELALLRGDLMLAQAAAHGAYHAAVAAAAKGKNMSPLYPFGMPGTDKDGRHGGIDSLTGLPHTILSDPSSVLGGVRLPPDTEIIKYTSSLAGPKSGAGTTTRGRKKTISLDPPHVSVHPADRNAPLPSKRPKLDEYGNSRSSVEVIRLPNKPDRPGHNSMSGTPPPNLSDYAGISRELLQTIASQSGVSLAALERQLAGSTGDYYAGLNLSTKMGEDSPLDLGVKSSAMDDDAPLNLSLKPTPASSQASDALSRLTSLSSSLNASSSHDRISRRKPGAKPRRVAPEMNPVPDAPRPKSSGSEDSESVAGWAGREGRPRNLGRGVSKPKKNTVASLLAQSRALGLRPALAHQLLAETDLEKLKALLGETASTDSECPSDSCPSDSDASDTSRRPNDAQLRLPLALGWKRVTVIKGLSRNCSIKGDVTYSPPDPHAGITMRSLHDVQNFLDSNPCPPLSTDNFSFSARTVLGEYIQPASDVGEPLVYNESEINKRLEEARLLASAGGRPTPPPLDRRMELARLQQAARDARRDASHRSRDQARLERSEKAELAKREKEARSQQLLEHINKNRTQLTIEPLPTVPKTGIDEWKTPEIVMGPATKTNKERIMPPISLSLIPVSGPKDSQNSPIKTIKFDQSGWKEEIEEYNALDKMKDFAEKAAFDLPKRKDKQYDFTLIKSAEKRLKAPDKENNLERLIESYSRITEFINGCDWSKLQEDKKSEDPKSIEQKYLDAKNEFMSQNLMLMPKDSPKSVLKDVIELSEDDDILTDIMSKKISKGTFNVGKDGALSISVHPLGKEATSSVRDTH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00364053;
90% Identity: iTF_00809166;
80% Identity: -