Hmer011960.3


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Hermaeophaga mercurialis
Gene Symbol
egg
Assembly
GCA_951812935.1
Location
OX638360.1:50248075-50252848[+]

Transcription Factor Domain

TF Family
MBD
Domain
MBD domain
PFAM
PF01429
TF Group
Unclassified Structure
Description
The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 2 1.7 9.9e+03 -2.9 0.0 46 69 193 207 191 213 0.57
2 2 1.3e-14 7.3e-11 42.4 0.0 4 74 704 767 701 770 0.89

Sequence Information

Coding Sequence
ATGGATGTGGACGAGATTGAGGATGATCCAATGGAAATTGATGACAGTCTTCCAGCAACCCCGATTATAGAACGTAGATCTAGTGATTTCACTTTGACGGGAACTGCACAAACGTCTTCAAACCCTACTGAAGCCGCAGAAACCCCAACCAATGAAAAGAATACAAGTGATGCAGATATTGTTATTTTAGACGATGATGAGGAACCAGAGAAAGATAAAGAGCAAGttgctgaaaataaaaatgaaaatgagacAACCGCAAATAGAGGCGAATCACCAGTAGAAGCCATTATAGATCTGGTAGAGAAACACAATAGTGTCCGTTGTTTGAACAGTACTTGTTGTGGTACTAACGCAGATTTCATCTTAGCACCAGATTTTTGTCTATCCTATTACAGAGTGAAAAGATCCAAGAGTTACAAAGAAGAGATATGCCAGTTGTGTTATGAAAAATCAGTCCAAGACTTTGATAACTTAACTACAAATCTAAAAAGCGGCAAGCTGATATTAGAATGTGAGTATCCTGTTATAAATGAAACGTTGCAAATAGAAGACAGTgatgaagaagaagaggaaaaagAACAAGATGTACAATATTTGGATAAAGAAAACTTTGATTTTATCAGTCAGAATATCGATGACATCATACAAAAGGCTTTAGATGAATTCAAAATTGAGGAACAATATAAGTTAGAGACAGCATATTTGAAAACTGAATCGGAAAGAGTTGAAGGGGATTATAAAGATCTGACCAAAAAAGTATCTGAAATTAggacagttttagataaaattcaAATAGATCTGTACAACCAATTTAGGCCAGAGCTCAAACCCCTCAAGGGACTCTCAATCATTGATGATCATGATATCGCTCcttcaattattataaaaactgATTCAGCATTAGATGCGAGTCCAAGAAAAAGCACTAGATCCCACAAACCCGTCTCTTACGTTGAACTCGATGAGATCGGAAATTCAAATAGTCCCAAAGTAGCTGCTCCCGCAACTGAAATTGAACCTCCTAAAGATCTACCACAAATTGTACCGATTGTAAGAATTCCTCCACAAATTGGTGAGATTTATTACATAGTCCGGGAAAATTCCCAAAGTAACTGGATAAGAGGTCGTTTGCAGGCCATAATAAATCCAGGTACCGCGTACAATGGACAAACGTACTCTACTGTGTATTACAAATTAGTAGAACTAAAACAGCAAAAGGAACGCCTAGTAAGCGGCAAGCAAATGGCTTATTTGCATCAGAGCAAGGTTCGTTTACCTGTCGGCACTAGAGTGATTTCGGTTTTTAAGGAGACAAGCGCCACAGGCCAAACGACAAAGTCCAGACACGATCCTTATTATGCGGGAGTGGTTGCCGAACAACCTTTCGAAGGAAATAAATACAGGTATTTGATATTCTTTGATATTGGCTACTCCCAGTATGTGAGTTACGATTATGTCAACTTGGTCCTCGAATCGAGTCCTAACGTATGGGAAGACATTTACGTGGACTCGAGgcctttcattaaaaaatacttggAAAGCCAGGATAGGCCGATGGTGAAACTGGCCAAAGATCAAACGGTCCGCGTTGAATATAACGGAAAATGGTGGCTGTGTACCGTCGTTAACGTGGACTGTTCCCTAGTACAAGTTTTCTTTGAAATGTTAAATAGAACAGAGTGGATATACAGAGGATCTACAAGATTAAGTCCCATGTTTAGAGAAGAACAAGCTGCTACGAACCGACACACTGGCCTTAGAACTTCAAGGAAATTAGGGCCTAATGAATCCCAAACGGTGGTACAGTATACAAGAAAAGACGATTTCGTACCTTCTGCGGAGAATCAAAATCAAGAATCTCCTACAAATGTCAGAGCCGTGGCTAGAAAAAGTACCACGAAACCTCAGGGTAATCCACAGATTGAAGGCGCTGTACCTTTCCTTCCTCAAGTAAAAGATCCACCCGTGAACCCCACTGGACCAACAAGCAAGATTATGtaCTTCACGCCTAGGGACCAGGTGATAATAAAAAGACAGTACAAACCCCATACCTGCGGTAGCAAATGCAAAGAGTTCCTTACTCACAATTTTAGCCAGCTACGTGGTCACAATCCACTTTCTAAACCGCTTTTGTGCGGTTGGGGTCGAATGACCCACAAAGCTAAGGGCAGAAAAGAAATTATCTACAAAGCTCCTTGTGGAAGGATTTTGCGGAACATAGCAGAAGTTCATTATTATCTCAGATTATCCCAAAGCGAAATGACAGTTGATTTGTTCGATTTCAATCATATGGTGAGATGTCTGGCCGAATTCAGCGTCGAATGCAATCCCGATCCGAAAGATCTTTCTAGAGGAATGGAACAAGTTCCTATACCGGTTATAAACGGAATAAACAACGAAATGTTGGATTTCTGCAACTACTCCATCAAGAGGGTACCCATGGAAGGTGTCCACATGAATGTGGACCAAGAATTTTTGTGCTGTTGTGATTGCGACGATGATTGTATCgacAAAACAAAGTGCTCTTGTTGGGGATTAACTCTAGGCGGCGCTAAGTACATCGGAAAGGACATCGACGCAAATTCCGTTGGTTACATTTACCGAAGACTTCCCGAACAAGTAATAACCGGAATATACGAATGCAATTCTAGGTGCAAATGTACGGCTACGTGTCTAAACAAAGTAGTTCAAAATCCGATGAGTCTGAAGTTACAGGTGTTCAGGACTCTTAATCGCGGTTGGGGTATAAGATGTTTAAATGATGTTCCGCAAGGTAGTTTCATTTGTATTTACGCCGGCACCATTCACACCGAAGCTATGGCGAAcgagGACGGTATGGCGTACGGAGACGAATATTTCGCCGAATTGGATTACATTGAAACCgttgaaaaatttaaagaagatTACGAAGCGGAGGTGTTggaagaagatgaagaagaacGGTGCAAGCGACGAAAGTCGCCGGTCGAAGAAGAGGATGAAGAAGATTCTATGACCCGATTGAGAAGAAGAAATCAGGATGAAGAAGCGGAGGAGAAAGTGAAAAAAGATGAAGTAAACAAACAAgaacaagaaattaaaattaaaaaggaaatggtTGAAGCGAAACAAGACCTCAAAGCAGCACTCGAGGGACTACCTGATAATATCGAAACTGTTACTATCAGCGACGAAGAAGATgaGGGTCGGgaagttttaagttttaatcCAAAGGCGAGTGGATTGGACGATAAAGGCCCTTCCTATGCTTCAGTTAGGGAATTGTTTGGCAAAGAGGAGTGCGTTTATGTAATGGATGCCAAAAACGCTGGCAATATCGGAcgatttttaaatCATTCGTGTTCCCCGAATGTGTTTGTTCAAAACGTATTTGTGGATACTCATGATCCCCGTTTCCCGTGGGTGTCATTCTTCTCTTCCCAGTTTATAAGGGCGGGAACGGAATTAACTTGGAATTACAATTATGATATTGGAAGCGTACCGGGAAGAGTCTTGTACTGCCATTGTTCCTCGTTGGAGTGTAAAGGACgtttgttgtaa
Protein Sequence
MDVDEIEDDPMEIDDSLPATPIIERRSSDFTLTGTAQTSSNPTEAAETPTNEKNTSDADIVILDDDEEPEKDKEQVAENKNENETTANRGESPVEAIIDLVEKHNSVRCLNSTCCGTNADFILAPDFCLSYYRVKRSKSYKEEICQLCYEKSVQDFDNLTTNLKSGKLILECEYPVINETLQIEDSDEEEEEKEQDVQYLDKENFDFISQNIDDIIQKALDEFKIEEQYKLETAYLKTESERVEGDYKDLTKKVSEIRTVLDKIQIDLYNQFRPELKPLKGLSIIDDHDIAPSIIIKTDSALDASPRKSTRSHKPVSYVELDEIGNSNSPKVAAPATEIEPPKDLPQIVPIVRIPPQIGEIYYIVRENSQSNWIRGRLQAIINPGTAYNGQTYSTVYYKLVELKQQKERLVSGKQMAYLHQSKVRLPVGTRVISVFKETSATGQTTKSRHDPYYAGVVAEQPFEGNKYRYLIFFDIGYSQYVSYDYVNLVLESSPNVWEDIYVDSRPFIKKYLESQDRPMVKLAKDQTVRVEYNGKWWLCTVVNVDCSLVQVFFEMLNRTEWIYRGSTRLSPMFREEQAATNRHTGLRTSRKLGPNESQTVVQYTRKDDFVPSAENQNQESPTNVRAVARKSTTKPQGNPQIEGAVPFLPQVKDPPVNPTGPTSKIMYFTPRDQVIIKRQYKPHTCGSKCKEFLTHNFSQLRGHNPLSKPLLCGWGRMTHKAKGRKEIIYKAPCGRILRNIAEVHYYLRLSQSEMTVDLFDFNHMVRCLAEFSVECNPDPKDLSRGMEQVPIPVINGINNEMLDFCNYSIKRVPMEGVHMNVDQEFLCCCDCDDDCIDKTKCSCWGLTLGGAKYIGKDIDANSVGYIYRRLPEQVITGIYECNSRCKCTATCLNKVVQNPMSLKLQVFRTLNRGWGIRCLNDVPQGSFICIYAGTIHTEAMANEDGMAYGDEYFAELDYIETVEKFKEDYEAEVLEEDEEERCKRRKSPVEEEDEEDSMTRLRRRNQDEEAEEKVKKDEVNKQEQEIKIKKEMVEAKQDLKAALEGLPDNIETVTISDEEDEGREVLSFNPKASGLDDKGPSYASVRELFGKEECVYVMDAKNAGNIGRFLNHSCSPNVFVQNVFVDTHDPRFPWVSFFSSQFIRAGTELTWNYNYDIGSVPGRVLYCHCSSLECKGRLL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00387244;
90% Identity
-
80% Identity
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