Hmel011839.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Heliconius melpomene
Gene Symbol
-
Assembly
None
Location
Hmel215003o:6379330-6395479[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 18 5e-05 0.0035 17.8 2.2 1 23 230 252 230 252 0.97
2 18 0.0036 0.25 12.0 0.7 1 20 258 277 258 280 0.94
3 18 1.4e-05 0.00095 19.6 5.4 1 23 299 321 299 321 0.98
4 18 0.00012 0.0081 16.7 4.7 1 23 327 349 327 349 0.99
5 18 2.2e-05 0.0015 19.0 5.3 1 23 355 377 355 377 0.97
6 18 7.1e-06 0.00049 20.5 7.3 1 23 383 405 383 405 0.97
7 18 4.6e-07 3.2e-05 24.2 2.9 1 23 411 433 411 433 0.97
8 18 6.3e-05 0.0044 17.5 6.7 1 23 439 461 439 461 0.97
9 18 0.00014 0.01 16.4 5.6 1 23 467 489 467 489 0.97
10 18 3e-07 2.1e-05 24.8 1.9 1 23 495 517 495 517 0.98
11 18 3e-05 0.0021 18.5 8.1 1 23 523 545 523 545 0.98
12 18 4.9e-06 0.00034 21.0 6.6 1 23 551 573 551 573 0.98
13 18 1.4e-05 0.00095 19.6 7.1 1 23 579 601 579 601 0.97
14 18 1.9e-06 0.00013 22.3 6.0 1 23 607 629 607 629 0.98
15 18 1.9e-05 0.0013 19.2 7.8 1 23 635 657 635 657 0.97
16 18 1.5e-06 0.00011 22.6 4.1 1 23 663 685 663 685 0.96
17 18 0.0013 0.094 13.3 0.6 1 23 692 714 692 714 0.95
18 18 0.0015 0.1 13.2 4.0 1 23 725 747 725 747 0.99

Sequence Information

Coding Sequence
ATGGGTCATCACTCACAGCAGCAGCATATCATGCAGCAGCAGCTGATGGCGGCCGCGCGTCCCGAACACGCAAACCAACAGATTCAGCTGACGGTAAGCGAGGATGGCATAGTAACAGTGGTGGAGCCCGGCGGCGGCGGGAAGCTTGTAGAGAAGGAAGAGCTTCATGAAGGTATCAAAATGCCTACAGACCACACTCTCACTGTGCACCAGTTGCAACAGATTGTTGGACATCACCAGGTGATCGACAGCGTCGTGCGCATAGAACAAGCGACAGGCGAACCCGCCAATATACTGGTGACGCAGAACCCGGACGGCACCACTTCTATAGAGACCAGCGCTGCCGACCCGCTCCTGGTGAAAGATGAGAAGAATGTCGCCAAAATTGAGTCTGCTCAATTTGCTATACCGGCGGAGATTAAGGATATTAAGGGAATCGATTTGAAGAGTGTTGGAGCTATGGGCATGGAAGGAGCAGTGGTTAAGATTTCAGCGGCATCTGAACACGATCTCCAACACGCCATGTATAAAGTAAATGTGGAAGATCTCTCGCAACTTCTGGCCTACCATGAGGTGTTTGGGAAACTTAATACTGAAAATCAACAACAGCCTAAGGTAATAACTGAAGTGGAAGTGGAGGCTGGCACCAGCGCCGCTATGTCGGAAGCGGAGTCATCTCCCGGACACCACTCATGCGACATATGCGGGAAGATATTCCAATTCCGATATCAACTTATTGTTCATAGACGTTACCACGGAGAAAGCAAACCTTTTACGTGTCAAGTTTGTGGCTCCGCATTTGCTAATCCGGTGGAATTGTCAAAACATGGAAAATGTCACTTGGCCGGCGATCCTGCCGAGCGTCAAGCAAAGAGACTGGCGCAGGACAAGCCCTACGCGTGTTCCACTTGCCACAAGACCTTCTCGCGTAAGGAGCATCTCGACAACCATGTCCGGAGTCATACTGGGGAAACTCCGTACAGATGTCAATTTTGCGCAAAAACATTCACTCGCAAAGAGCACATGGTGAACCACGTGCGCAAGCACACCGGCGAGACGCCGCACCGCTGCGAGATATGCAAGAAGAGCTTCACGCGCAAGGAGCACTTCATGAACCACGTCATGTGGCACACTGGTGAAACGCCGCACCATTGTCAAATATGCGGCAAGAAGTACACTAGGAAGGAGCATTTAGTGAATCATATGAGGTCTCATACGAATGACACGCCGTTCAGGTGCGATTTGTGCGGCAAGTCCTTCACCAGGAAGGAACACTTCACCAATCACATATTGTGGCACACCGGTGAAACTCCACATCGATGTGACTTCTGCTCTAAAACTTTCACTCGTAAAGAGCACCTGCTGAACCACGTGCGTCAACATACTGGGGAATCACCGCATCGATGCAATTTCTGTGCAAAGTCCTTCACAAGACGAGAACACTTAGTCAATCATGTGCGACAACACACTGGTGAAACGCCTTTCCAGTGCGGATACTGCCCTAAAGCGTTTACAAGGAAAGATCATTTAGTAAATCATGTTCGTCAACACACGGGAGAGTCCCCACATAAATGTACATTCTGTACGAAATCTTTTACACGTAAAGAGCATTTAACAAATCATGTGCGGCAACACACTGGGGAATCCCCACATCGATGTACATACTGCGCCAAGTCTTTCACTAGGAAGGAGCATCTTACAAATCATATAAGACAACATACGGGTGAAACGCCATTCAAATGCACATACTGCTCGAAGTCGTTCTCGCGTAAGGAGCATCTCACGAACCATGTACATCTTCACACTGGTGAAACACCGCATAAGTGTCCGTTCTGTACTAAGACATTCTCTAGGAAGGAACACTTAACTAACCATGTCAGGATACATACAGGTGAATCTCCACACAGGTGCGAGTTCTGTAACAAAACATTCACAAGAAAGGAACATTTAACCAATCACTTGAAGCAGCACACGGGAGACACGCCGCATGCTTGTAAAATATGCTCCAAGCCGTTCACCAGGAAAGAACATTTAGTAACACATATGAGATCCCACAGTTGTGGGGAGAGACCACACATTTGCGGTGAATGTGGAAAATCCTTCCCCTTGAAGGGTAATCTGCTGTTCCACGAGAGGTCACACAATAAAGGCGCCAATGCGTCAAACAAAACGTTCCGTTGTGACGTGTGCTCCAAGGAGTTTATGTGCAAAAGTAATTTAGTATCCCATCGAAGAACCCACACAGAAACGGGCGAGGGTGCTACAACCACAGAGCCCACACCTGAAAATGAAGATTGTGGAGATTGCAACAAGTGCGACAAAGACTCACCAGAAAGACCTGAGAGGAAACATGATACTAGAGCGTCATCAGAAAACAGAGCTACTACTGAAGCAAGTGCTGCACAAAATCCATCGCCAAATCCAAACCCAACTGTCATGCAAATTAATAGTCAGCAAGTGCGAACGGGCCCTACAACGACCGCCAGCGTGGCAACAGGCACTTTCACCCACACCGCCACCACCCAACACCACGCCTCTAGCAGTATAGCCCACCACCCTGTTACCGTCAATTACTAG
Protein Sequence
MGHHSQQQHIMQQQLMAAARPEHANQQIQLTVSEDGIVTVVEPGGGGKLVEKEELHEGIKMPTDHTLTVHQLQQIVGHHQVIDSVVRIEQATGEPANILVTQNPDGTTSIETSAADPLLVKDEKNVAKIESAQFAIPAEIKDIKGIDLKSVGAMGMEGAVVKISAASEHDLQHAMYKVNVEDLSQLLAYHEVFGKLNTENQQQPKVITEVEVEAGTSAAMSEAESSPGHHSCDICGKIFQFRYQLIVHRRYHGESKPFTCQVCGSAFANPVELSKHGKCHLAGDPAERQAKRLAQDKPYACSTCHKTFSRKEHLDNHVRSHTGETPYRCQFCAKTFTRKEHMVNHVRKHTGETPHRCEICKKSFTRKEHFMNHVMWHTGETPHHCQICGKKYTRKEHLVNHMRSHTNDTPFRCDLCGKSFTRKEHFTNHILWHTGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCNFCAKSFTRREHLVNHVRQHTGETPFQCGYCPKAFTRKDHLVNHVRQHTGESPHKCTFCTKSFTRKEHLTNHVRQHTGESPHRCTYCAKSFTRKEHLTNHIRQHTGETPFKCTYCSKSFSRKEHLTNHVHLHTGETPHKCPFCTKTFSRKEHLTNHVRIHTGESPHRCEFCNKTFTRKEHLTNHLKQHTGDTPHACKICSKPFTRKEHLVTHMRSHSCGERPHICGECGKSFPLKGNLLFHERSHNKGANASNKTFRCDVCSKEFMCKSNLVSHRRTHTETGEGATTTEPTPENEDCGDCNKCDKDSPERPERKHDTRASSENRATTEASAAQNPSPNPNPTVMQINSQQVRTGPTTTASVATGTFTHTATTQHHASSSIAHHPVTVNY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00777488;
90% Identity
iTF_00778166;
80% Identity
-