Hsub002636.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Harpagoxenus sublaevis
Gene Symbol
Hr39
Assembly
GCA_030770355.1
Location
JASTWR010000008.1:541581-545787[+]

Transcription Factor Domain

TF Family
SF-like
Domain
zf-C4|SF-like
PFAM
AnimalTFDB
TF Group
Zinc-Coordinating Group
Description
The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 5 1.2 2.8e+04 -4.5 8.4 124 167 36 74 19 96 0.55
2 5 1.2 2.9e+04 -4.6 10.2 68 164 302 398 231 441 0.63
3 5 2 4.8e+04 -7.1 8.4 77 143 443 509 406 542 0.39
4 5 4e-08 0.00097 20.1 0.0 1 21 609 629 609 634 0.92
5 5 2.4e-70 5.8e-66 225.0 0.0 189 408 791 1001 746 1001 0.91

Sequence Information

Coding Sequence
ATGTCAGAGCAAAACGGGCCCAGCGAGGGCCCAGGGCCAGGGCCCGGCTCGGATTCGGGCTGGTGGCCAAACACGCAGCCTTGGAAATCGTCGGCGGCCGCCTCGTCGTCGACTTCGTCGACTCCCACTTCGGCGGCAGGTTCCGCATCCGTCTCTGTATCCTGCTCCGCGTCCAGCTCATCCTCGACGAGCTCATCTTCCACCTCGGCCAACTCATCCGCGACCTGTTGTCCCTCATCCTGCATCGGCGTGTCCTGCACGATGAGCCCGAGCCGCTCCACGGAAACGGGGAAAAACGTGTCCGTCACCACTATTAACGTACCGCCCAATCAAGAAATGCACGATGGTAAAGGAGTATGTAAATATCTCGGGGGACAGAATGGCGTGACGGTGTCGGTGGTATCGACCTCGGTACTAGGATGTGGAAACGCGAATGCCGTCCCGTCAAGCGGAATCTGCACGAATACGGGGCCGCATAGTATCGGTATCGGAATCGGCGGCATCCTCGCCGCGAACGCGGCCGACATCGATGATCTCGAGGACAGCGACGGCGAGATCAGCAAGATTGACTTTAGAGGCGTCAATCTACGTTCGAAGAAGAAACGCGACGTATCGGGTAATCAGAATGGCGACAAGATCGGTGACGGAGAAGCAAACGGCGACGGCGGAGGATGCTGCGATGACAATTCACAACAGCAGCCAGAGAGGCCTATGTCATGGGAGGGTGAACTATCGGACCAAGAAATGTCTTCCAATACAATTACTAATCAGGACCACAATGAGGAAACGTCTATGGAGGGGGTTCAAGTATGCAGCACGAGCCCTGGGCCCATGGAACAGAAGTTTCCTATTAAGTCGGAGCCGGATTTTCGATCTAGCCCAGGTTTCACAATAAGATCCTTTCACGATGGTGGACTGCCCATGACACACAATCAACAActgcagcaacagcaacagcaacaacgCGGTATCGAAAATCTCGAACAGACGCAACAGAGCGACCTACCGCTTCTCGTAGGCAAGCTTCTCGGTGGATACAACAACTCAACGCCTAATCACAGTCCTGTTCTCAATCCGCGACATCATCTAACTAAACACAGTCATACTAGATCGCAGGTGCCGTCACCAGATTCCGCCATTCATTCTACGTACAGTGTCTTCAGTTCACCGACACAGAGCCCCCACGCGGCACGGCATTCCGCCCTAGGAGCGGGTAGTCCGATACCCTCCTCGTCGCTGTCCCTTTCTCGACACAGCTTCAACAATTCGACTTCCTCGTTATCCCTATCGCTGTCGCATTCGCTTTCGAGGAACAATTCCGACGCTTCCAGTAGCTGCTACAGCTACGGCTCGCTTAGCCCGCCTACGCATTCACCCGTCCAGCAGTCGAGACATCCGCATTCGCACTCGCAACATCATCAGCATCAAGTGGCGCAAGGTAGTCCGCTACATCTACCAGTCTCGTCCGCAGTCGCCGCACATCATTACTCGTCCTCTTCCGTACCAGGCTCGGAACTATCGCCGGACGGCCATCCCGTCGCGGAGGATCAGGAAGACTGTAGGATACCATCAGCGCCGTCGGGTATCTCTACAAGGCAACAACTGATAAACAGCCCCTGCCCGATTTGCGGCGACAAGATAAGCGGCTTCCATTACGGCATCTTCTCGTGTGAATCGTGCAAGGGATTCTTCAAGCGCACCGTCCAGAATCGCAAGAACTATGTGTGCCTTAGAGGCGCAGGCTGCCCGGTCACCGTGGCCACGAGAAAGAAGTGCCCGGCCTGCCGCTTCGACAAGTGCCTCAACATGGGTATGAAACTCGAGGCGATCAGGGAGGATCGTACCAGAGGCGGTAGAAGCACTTATCAATGTACCTACACTCTACCGGCAAATCTCGTTGGTAGTCCTGCCGGCGGTATGACCGGTGAAAAACTAACGGCGGGCAATTGCAGTCCGGCACCGGCCGGTAGCGAGCACCATTATTCCGTTAGATATCATTCAAATCATTCTCACAAGATGCAAGTAGTACCTCAACTTTTGCAAGACATCATGGATGTAGAACATCTTTGGCATTATAACGACAATGATCGGGTAAGCGGCAGTGGAGGGGTACTTGGAAGTGTAAGGAATAACAGTGGTGACAGTATGCTGTTCGGTGGATCCGGAAGTGGTCTGACGCCCAGCGGTATTGGAACCGCGACCGGTATTGGCGCCGGAAACAACGGAGGTGCAGTGGAATGTTCGTCGAATGACTCTAGTAACGTCGATACTAATAGTAAGAGAGGAGAGACGGCGAGCCCTGCCGGTTCGACCTCAACGGGAGCGTCTGATCAACATTCCACAAATGGCAATACCACCAACAATAGTAATTCTCAAATCGCCAGTAATTCCAATGGCAATTCAGCGCAGCATCCGGACTTTCTATCTAATCTGTGCAACATCGCGGATCATCGGCTTTATAAGATCGTCAAGTGGTGCAAGAGTCTgccattatttaaaaatatctcgaTCGACGATCAAATCTGTTTGTTGATCAACTCTTGGTGCGAGCTATTACTTTTCTCCTGCTGTTTTCGCAGCATGGGCACTCCCGGTGAGATAAGAGTGTCTCTTGGCAAGTCGATTACTCTAGAACAAGCAAGACAGCTTGGTTTAGCGACTTGCATCGAAAGGATGCTCGCTTTTACCGACAATCTGCGAAGACTGAGGGTAGACCAATACGAATATGTTGCAATGAAGGTGATCGTGCTGTTAACGTCCGATACAAGCGAATTAAAGGAGCCTGAGAAGGTCAGAGCTTCTCAGGAAAAAGCCCTTCAAGCACTGCAGCAATATACAATTGCGAGGTATCCAGAAATGCCTGCCAAATTCGGTGAACTATTGTTGAGAATTCCAGATCTGCAAAGAACATGTCAAGCAGGAAAAGAATTGCTCAGTGCAAAACGCGCCGAGGGAGAAGGCAGCTCGTTTAACCTTTTAATGGAATTGTTGAGAGGAGATCACTGA
Protein Sequence
MSEQNGPSEGPGPGPGSDSGWWPNTQPWKSSAAASSSTSSTPTSAAGSASVSVSCSASSSSSTSSSSTSANSSATCCPSSCIGVSCTMSPSRSTETGKNVSVTTINVPPNQEMHDGKGVCKYLGGQNGVTVSVVSTSVLGCGNANAVPSSGICTNTGPHSIGIGIGGILAANAADIDDLEDSDGEISKIDFRGVNLRSKKKRDVSGNQNGDKIGDGEANGDGGGCCDDNSQQQPERPMSWEGELSDQEMSSNTITNQDHNEETSMEGVQVCSTSPGPMEQKFPIKSEPDFRSSPGFTIRSFHDGGLPMTHNQQLQQQQQQQRGIENLEQTQQSDLPLLVGKLLGGYNNSTPNHSPVLNPRHHLTKHSHTRSQVPSPDSAIHSTYSVFSSPTQSPHAARHSALGAGSPIPSSSLSLSRHSFNNSTSSLSLSLSHSLSRNNSDASSSCYSYGSLSPPTHSPVQQSRHPHSHSQHHQHQVAQGSPLHLPVSSAVAAHHYSSSSVPGSELSPDGHPVAEDQEDCRIPSAPSGISTRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCLRGAGCPVTVATRKKCPACRFDKCLNMGMKLEAIREDRTRGGRSTYQCTYTLPANLVGSPAGGMTGEKLTAGNCSPAPAGSEHHYSVRYHSNHSHKMQVVPQLLQDIMDVEHLWHYNDNDRVSGSGGVLGSVRNNSGDSMLFGGSGSGLTPSGIGTATGIGAGNNGGAVECSSNDSSNVDTNSKRGETASPAGSTSTGASDQHSTNGNTTNNSNSQIASNSNGNSAQHPDFLSNLCNIADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSMGTPGEIRVSLGKSITLEQARQLGLATCIERMLAFTDNLRRLRVDQYEYVAMKVIVLLTSDTSELKEPEKVRASQEKALQALQQYTIARYPEMPAKFGELLLRIPDLQRTCQAGKELLSAKRAEGEGSSFNLLMELLRGDH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01267641;
90% Identity
iTF_00885153;
80% Identity
iTF_00765736;