Gmor003191.1
Basic Information
- Insect
- Glossina morsitans
- Gene Symbol
- Lztr1
- Assembly
- None
- Location
- scf7180000647750:48047-53157[-]
Transcription Factor Domain
- TF Family
- BTB
- Domain
- zf-C2H2|ZBTB
- PFAM
- PF00651
- TF Group
- Zinc-Coordinating Group
- Description
- The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 4 8e-13 1.2e-10 41.0 0.2 1 107 499 637 499 640 0.88 2 4 0.22 33 4.2 0.2 77 108 639 670 634 672 0.90 3 4 4.2e-19 6.2e-17 61.2 0.0 8 97 731 820 725 835 0.84 4 4 2.1 3.1e+02 1.1 0.1 72 106 829 863 822 866 0.86
Sequence Information
- Coding Sequence
- ATGTTAAACGCTATATACTCGGCGGCCGATAACCAAGACGGCTCTGGCAGTAGCACCAGCAGTGGCAGTGCAGCTGGTAGTTGTGGTGGCAGCGGCGGAGGTGGTAATTTTTTCAATTCTGGATTACGTTATAATTTTTGTGGCGGTGGTTGTCATGCTTCGCCTCCAGCAACATTTTCTGTAATAACACCACAACAGCAGTGTAATACTCAACTCTCCGTGTCAAGTCAGTCGGCTCCGGCCACTGCGACGCATGTTAAAATACTAAAGACAGGATTTTGTCTTGCTTGTCAAGATAAATATTTTGGCGGCGTTCCTGGCGTTGCTTGCAAAAAAGTAGAACGTAAAAGTCGCCGTAGCTTTGTAACTCGTAGTTGTAATAAAATGTCACATTCCAGTACAAATTCAGTTCGCAGCAATCAATTTTCACGTAACTGCAAATCCGTGTCACCGGGCAGTTATAGTTGCAATGCCTTGAATGTGGACTTCAGTTCATATACGGCCACCCATCAGTGGACAAAAATGTTGGAATGTGCTGAATTTGTGGGAGCCAAACGCAGTAAACACACTGTGGTAGCTTACAAAGATGCCATGTATGTGTTTGGAGGTGATAATGGTAAAACAATGTTAAACGATTTAATTCGGTTTGGCGTAAAAGATAAGTCATGGGGACGTGCTTGCGCCACAGGCACGCCACCTGCACCCCGTTATCATCATTCCGCTGTAGTTTATGGTAATTCCATGTTTATTTTCGGTGGCTATACCGGCGACATACACTCCAATTCCAATCTAACAAATAAAAATGATCTATTCGAATACGAGTTTCAACGTGCCATGTGGGTGGAATGGAAATTTTTAGGAAAAATGCCTGTACCACGCTCCGCACATGGAGCTGCTGTTTATGATAACAAAATGTGGATTTACGCTGGGTACGATGGCAACGCTCGCTTAAATGATATGTGGACATTAAATTTAACAGGAGAAAACCATCAATGGGAAGAGGTAGAGCAAAAAGGAGAACGTCCCCCAACCTGTTGTAATTTCCCAGTGGCAGTGGCTCGTGATTGTATGTACGTGTTTTCAGGGCAAAGTGGTATGCAAATCACCAACTCTTTGTTCGAATTCAACTTCAAAACCAAAACATGGCGCCGTATTGGCAATGAACACGTCTTACGTGGGGTGGCTTCTCAACCACCAGCTAGACGTTATGGTCATACCATGGTCCATCATGATCGTTTTCTCTATGTTTTTGGTGGCTCTGCCGATTCGACGTTACCCAACGATTTGCATTGCTATGATCTAGATTCGCAAGTTTGGTCAATAATACAACCTGAAGCTAATTCAGACGTTCCGTCGGGCCGAGTTTTTCATGCCAGTGCTGTTATTAGCGACGCCATGTACATTTTTGGTGGGACTGTAGATAACAGTGTCAGACGAGGTGACACCTATCGTTTCCAATTCTCCAGTTATCCCAAGTGCACCTTACGGGAAGATTTCGGCAAATTTTTTAATGATAAACAATTTTGCGACATTCAGTTCATAGTCGGTCCTGAGGAAATTAAAATAATGTCTCATATAGCTTTTGTCGCCGCCAGATCAAAGTATTTGCGCACTAAAATCTTAGCAGCTCGTGACGCTAGGCATCAGCAAATGGAGAAAGTATTCGGTTCAGGTTGTGTGGAAGTTCGGACTTGTTCGCCGAGTGCGAACCATGAGCCGCTTCTTGAAGTTCGTTTGCCTAATGCAAATCCCGAAGCATTTGAAATCATTCTTAATTATATCTATACTGATCGCATAGACCTTAAGGAACCCTATACAAAGAATATCATCATATTAATTACGGACATTTACCAATTGGCCGGGCTCTTCTTAATGCCACGTTTAGCGCATGGATGTATACAGTACTTGGATTTCAAGATAAATAAACAAAATGTCCTGGAAGCTCTTTACAACGCTGATAGGAAAAAAATACAAATAGTGAAAGATCATTGCATGCAATTTATTATAAAGGAGGAGAACTTTACTGATGTCGTTATGTCGAACGAATTTAGTGATTTAGATAAACCTTTATTGGTAGAGATAATACGTAGACGTTTGAACCCGTGTAAGATTGTCAATGAAGCTAATTTAGAAAAGAACGTGGGAAATACGCTGGAAAGTGATATGGCAGTATTTTTAGAGTCGACGGGTAAGGACTTTTGTGATATAAATCTTATGTTAGAAGGTCGAGTTATACCGGCTCATAAATCGATCTTATCGGCACGCACGCAATACTTTCAAGGCATGTTTCGTTCATTTATGCCTCTCGATAATACAGTGAATATATCCATTGGTGATATATTACCTTCACCAGAAGCTTTTCAATCTCTCTTACGTTACATATATTACGGTGAAACGAAACTACCGCCTCAAGATGCCCTATATCTATTTCAAGCCCCTAATTTTTATGGTCTTGCCAATAATCGCTTGCATTCGTTTTGCAAGTATTCCCTCGAGCACAATATCAATTATGAGAATGTTTTGCAGACCCTTGAAGCTTCCGATTACACAAAAATTTATGATATCAAGGATCACGCTTTGAAATTAATTGTTAAGGATTTTTCCCGAGTAGCAAGATTGCCGAAAATTTCAAGTTTATCACGTGAGCTTTTATTGGACATTATACAGGCGGTGGCCGATTCGCACGGTGAATTTTTAACGCGCATTAGTATTAATACTGATATATGA
- Protein Sequence
- MLNAIYSAADNQDGSGSSTSSGSAAGSCGGSGGGGNFFNSGLRYNFCGGGCHASPPATFSVITPQQQCNTQLSVSSQSAPATATHVKILKTGFCLACQDKYFGGVPGVACKKVERKSRRSFVTRSCNKMSHSSTNSVRSNQFSRNCKSVSPGSYSCNALNVDFSSYTATHQWTKMLECAEFVGAKRSKHTVVAYKDAMYVFGGDNGKTMLNDLIRFGVKDKSWGRACATGTPPAPRYHHSAVVYGNSMFIFGGYTGDIHSNSNLTNKNDLFEYEFQRAMWVEWKFLGKMPVPRSAHGAAVYDNKMWIYAGYDGNARLNDMWTLNLTGENHQWEEVEQKGERPPTCCNFPVAVARDCMYVFSGQSGMQITNSLFEFNFKTKTWRRIGNEHVLRGVASQPPARRYGHTMVHHDRFLYVFGGSADSTLPNDLHCYDLDSQVWSIIQPEANSDVPSGRVFHASAVISDAMYIFGGTVDNSVRRGDTYRFQFSSYPKCTLREDFGKFFNDKQFCDIQFIVGPEEIKIMSHIAFVAARSKYLRTKILAARDARHQQMEKVFGSGCVEVRTCSPSANHEPLLEVRLPNANPEAFEIILNYIYTDRIDLKEPYTKNIIILITDIYQLAGLFLMPRLAHGCIQYLDFKINKQNVLEALYNADRKKIQIVKDHCMQFIIKEENFTDVVMSNEFSDLDKPLLVEIIRRRLNPCKIVNEANLEKNVGNTLESDMAVFLESTGKDFCDINLMLEGRVIPAHKSILSARTQYFQGMFRSFMPLDNTVNISIGDILPSPEAFQSLLRYIYYGETKLPPQDALYLFQAPNFYGLANNRLHSFCKYSLEHNINYENVLQTLEASDYTKIYDIKDHALKLIVKDFSRVARLPKISSLSRELLLDIIQAVADSHGEFLTRISINTDI
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01055302;
- 90% Identity
- iTF_00748289;
- 80% Identity
- -