Basic Information

Insect: Glossina morsitans
Gene Symbol: Hr39
Assembly: None
Location: scf7180000651779:42111-90102[+]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 4 0.21 1.3e+03 -2.1 6.4 127 190 155 218 106 248 0.59

2 4 2 1.2e+04 -7.4 13.9 50 170 250 384 235 407 0.56

3 4 9.9e-18 6.1e-14 51.7 5.5 1 151 504 694 504 708 0.72

4 4 3.7e-81 2.3e-77 260.6 1.3 186 408 693 903 688 903 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	4	0.21	1.3e+03	-2.1	6.4	127	190	155	218	106	248	0.59
2	4	2	1.2e+04	-7.4	13.9	50	170	250	384	235	407	0.56
3	4	9.9e-18	6.1e-14	51.7	5.5	1	151	504	694	504	708	0.72
4	4	3.7e-81	2.3e-77	260.6	1.3	186	408	693	903	688	903	0.94

Sequence Information

Coding Sequence: atgtctaacattaaaacggaaaaTGCTAGCGGGCTAGCTATAGTAAATACTTCCTCCGCAACGACAACGTCTGGAAGCGGTAATTCATCATTTCAATTGCCGGTCAATATGAGCAATCATATGATGACCGATCGAACCTCGTCCATTATTACTTCTACTACTACAACAAATCGCAATATTTCTGTAACAAATATTAAATGTGAAGTTGACATAGATGTGGCTACATCAACGGCTTCTGGTGGAAACACGGTGTCGATAGGTTTTTACAATGGAGCACGTGTAGCAAACTGCACTACCGGCTTAGGCATTCGAATACCGGTGACTAAGGCCGAAGACTCAGATTCAGAGACGGAATTAACTAATATTGAAAACCTTAAAGTTAATCGTAGAATAACCAGCTCGAGTGGCAATTCAGGTAGTGGCAATCATCATAATGCACCGCGGCCTATGTCTTGGGAAGGAGAACTTTCGGAAAGTGAGGATACAACCGAAGCAGAATTAATGGATACGGATACCACCATGAGTAATAGTGCTGTGTCACAGCCACAAAGTTCGGCGACGGTTATTAAAAGCGAAGTATCGACTACAACGCCATCCACTACGCAAActataaagcctataaagcctGAAATAGAACAAATAGCAGTAGAAGTTCACCATCACACGGCAGCGAATAGCGGTGGCATGGGTAGTATTTATCACCCTAAATTAAAATTAGCACCTACGCAAAGTGATCCTATCAATCTAAAATATGAGCCACCTGACCATTCGGGTTTGAATAATTCGCCCTTGTTGGCCCGACAGAAGTCAAGCACAGCTTTGACTCATCTGCCCGCTAATCCAAGTCCCGACTCGGCCATACATTCCGTATATACACATAGCTCACCTTCGCAGTCACCATTAACATCTAGACATGCACCCTATACTCCGTCGCTGTCGCGCAATAATAGTGATGCTTCCCATAGCTCTTGCTATTCTTATTCCTCGGAATTTAGTCCTACGCACTCGCCTATTCAAGGTCGTCATCCTGCGCCTCATGTTGTATATGGTAATTACAATGGTTCAACACCCGGTAATATGCATCATTCCACTTTACTTTACCGGCCTCTTAGCACGACAGCCAATTCAACAACTGCTGCCAGTAAATTGGAAACGGTTGGTAATGAAGTACAGAACTTAAGTATGGATGCAAATGGCTCAACTTCTGCGTCTACCGGTGCTTTTAACATTACCACAGATGTGAATGGTTTACCCACTTCACCAGCAGCTGGTATTTCGCGGCAACAACTAATTAATTCCCCGTGTCCTATTTGTGGAGATAAAATTTCAGGCTTCCATTATGGCATTTTCTCATGCGAGTCATGTAAAGGtttttttAAACGTACCGTCCAAAATCGCAAGAATTACGTATGTGTTCGGGGTGGACCATGTGTGGTAAGCATTACTACCCGTAAAAAGTGCCCGGCTTGTCGTTTCGAAAAATGTCTTCAAAAAGGTATGAAATTAGAAGCAATACGGGAAGATCGCACCAGAGGAGGACGTTCTACATACCAATGTTCCTACACATTGCCGAATTCTCTAATGAGTCCAATTCTATCAGCAGATCAGCAACAAAACACAGCACAAAGCTTAATAAATGCTCAAACACAACAGCAACAGTCGCAGTCTCAAATTCAGCAGTTGCAGCAGCAACCGCAACCACCACCGCAACAGCAACAACGTTTAGTCGCACCTTTGCAGAGTAGTTACAACAACACTTCCAATGCCAACGGTTATGTTCCGGGACTAGGATCCAATATTAAAACCGAACATTCGGTAATCGCTCCTCCTGCCTTGAACAATATTAATTTGAATTCTAGTTCACGTACTCTCATTCTAAACTCCTCTTCTTCCGCTGGTGACAACGCTATACATGACAGCAGTATTCCCACACTCTTACAGGAAATTATGGACGTGGAACATCTTTGGCAATACACGGTTGCTGAATTAGCGCGACTCAATCAACCGCTAATTTCACCCTCTTCGAGTTCAACTTCTTCAAACACCGTTTCCACAAATGTAGCAACAACAAGTCAAATGACCAACCCACTGCTGGCCAGTGCTGGCCTCTCATCCACTACCAACCCTGATTTAATAGCACATCTTTGTAAAGTAGCCGACCATCGTTTATATAAGATTGTCAAATGGTGTAAAAGTTTGCCGCTATTCAAAAATATATCGATTGACGATCAAATATGCCTGCTAATCAATTCCTGGTGTGAGCTTCTATTGTTCTCTTGCTGTTATCGTTCCATAGATACACCTGGAGAAATTAAAATGTCACAAGGTAAAACTGTTAACTTGGCTCAAGCAAAATTAACTGGTTTTCAGACCTGCATTGAAAGAATGCTGAATCTGGCAGATCATTTAAGACGTTTAAGGGTTGATCGTTACGAATATGTGGCCATGAAAGTGATAGTATTATTGCAATCCGACACATCAGAATTGCAAGAGCCCGTAAAGGTTCGAGAATGTCAAGAGAAAGCTTTGCAAAGCTTGCAAGCTTACACTTTGGCTCATTATCCGGATACTCCTTCCAAGTTTGGAGAATTACTTTTACGTATACCCGATTTGCAACGAACATGTCAATTGGGTAAAGAAATGCTTTCTATTAAATCTCGTGATGGTGGTGATTTTAATTTATTAATGGAGCTTTTAAGAGGAGAACATTGA
Protein Sequence: MSNIKTENASGLAIVNTSSATTTSGSGNSSFQLPVNMSNHMMTDRTSSIITSTTTTNRNISVTNIKCEVDIDVATSTASGGNTVSIGFYNGARVANCTTGLGIRIPVTKAEDSDSETELTNIENLKVNRRITSSSGNSGSGNHHNAPRPMSWEGELSESEDTTEAELMDTDTTMSNSAVSQPQSSATVIKSEVSTTTPSTTQTIKPIKPEIEQIAVEVHHHTAANSGGMGSIYHPKLKLAPTQSDPINLKYEPPDHSGLNNSPLLARQKSSTALTHLPANPSPDSAIHSVYTHSSPSQSPLTSRHAPYTPSLSRNNSDASHSSCYSYSSEFSPTHSPIQGRHPAPHVVYGNYNGSTPGNMHHSTLLYRPLSTTANSTTAASKLETVGNEVQNLSMDANGSTSASTGAFNITTDVNGLPTSPAAGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCVRGGPCVVSITTRKKCPACRFEKCLQKGMKLEAIREDRTRGGRSTYQCSYTLPNSLMSPILSADQQQNTAQSLINAQTQQQQSQSQIQQLQQQPQPPPQQQQRLVAPLQSSYNNTSNANGYVPGLGSNIKTEHSVIAPPALNNINLNSSSRTLILNSSSSAGDNAIHDSSIPTLLQEIMDVEHLWQYTVAELARLNQPLISPSSSSTSSNTVSTNVATTSQMTNPLLASAGLSSTTNPDLIAHLCKVADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCYRSIDTPGEIKMSQGKTVNLAQAKLTGFQTCIERMLNLADHLRRLRVDRYEYVAMKVIVLLQSDTSELQEPVKVRECQEKALQSLQAYTLAHYPDTPSKFGELLLRIPDLQRTCQLGKEMLSIKSRDGGDFNLLMELLRGEH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00749017;
90% Identity: iTF_00747508;
80% Identity: iTF_00749017;