Basic Information

Insect: Glossina fuscipes
Gene Symbol: Hr39
Assembly: None
Location: Scaffold148:87538-96765[+]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 4 0.13 2.5e+03 -2.3 3.9 115 162 156 202 103 243 0.57

2 4 1 2e+04 -6.4 13.4 50 160 247 376 227 395 0.59

3 4 2.1e-17 4.1e-13 49.7 4.7 1 150 501 691 501 705 0.64

4 4 2.3e-81 4.5e-77 260.3 1.1 190 408 694 900 686 900 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	4	0.13	2.5e+03	-2.3	3.9	115	162	156	202	103	243	0.57
2	4	1	2e+04	-6.4	13.4	50	160	247	376	227	395	0.59
3	4	2.1e-17	4.1e-13	49.7	4.7	1	150	501	691	501	705	0.64
4	4	2.3e-81	4.5e-77	260.3	1.1	190	408	694	900	686	900	0.95

Sequence Information

Coding Sequence: atgtctaacattaaaacggaaaaTGCTAGCGGGCTAGCTATAGTAAATACTTCCTCCGCAACGGCAACGTCTGGAAGCGGCAATTCATTATTTCAATTGCCGGTCAATATGAGCAATCATATTATGACCGATCGAACCTCGTCCATTATTACTTCTACTACTACAACAAATCGCAATATTTCTGTAACAAATATTAAATGTGAAGTTGACATCGATGTGGCTACATCAACGGCTTCTAGTGGAAACACGGTATCGATAGGATTTTACAATGGAGCTCGTGTGGCAAACTGCACCACCGGCTTAGGCATTCGAATACCGGTGACTAAGGCCGAAGACTCCGATTCAGAGACGGAATTAACTAATATTGAAAATCTTAAAGTTAATCGTAGAATAACCAGCTCGAGTGGTAATTTAGGTAGTGGCAATCATCATAATGCACCACGGCCTATGTCTTGGGAAGGAGAACTTTCGGAAAATGAGGATACAACCGAAGCCGAATTAATGGATACGGATACCACCATGAGTAATAGTGCTGTGTTACAGCCACAAAGTTCGGCGACGGTCATTAAAAGCGAAGTATCAACTACAACACCATCCACTACGCAAACTGTAAAGCCTGAAATAGAACAAATAGCAGTAGAAGTTCACCACCACACGGCAGCGAATAGCGGTGGCATGGGTAGTATTTACCACCCTAAATTAAAATTAGCACCTACGCAAAGTGATCCAATCAATCTAAAATATGAGCCGCCTGACCATTCGGGTTTGAATAATTCGCCTTTGTTAGCACGACAGAAGTCAAGCACAGCTTTGACTCATCTGCCCGCTAATCCAAGCCCCGACTCGGCCATACATTCCATATATACACATAGTTCACCTTCGCAGTCACCATTAACATCTAGACATGCTCCTTATACTCCGTCGCTGTCGCGCAATAATAGTGATGCTTCCCATAGCTCTTGCTATTCTTATTCCTCAGAATTTAGTCCTACGCATTCGCCTATTCAAGGTCGTCATCCTGCGCCTCATGTTGTATATGGTAGTTACAATGGGTCAACACCCGGTAATATGCATCATTCCACTTTACTTTACCGGCCTATTAGCACGACAGCCAATTCAACAGCTTCTGCCAATAAATTGGAAATGGTTGGGAATGAAGTACAGAACTTAAGTATGGATGCAAATGGCTCAACTTCTGCGTCTAGCGGTCCTTTTAGTATTACCACAGATGTGAATGGTTTACCTACTTCACCAGCAGCTGGAATTTCGCGGCAACAACTAATTAATTCCCCGTGCCCTATTTGTGGAGATAAAATTTCAGGCTTCCATTATGGCATTTTCTCATGCGAGTCATGTAAAGGtttttttAAACGTACCGTCCAAAATCGCAAGAATTATGTATGTGTTCGGGGTGGACCATGTGTGGTAAGCATTACCACCCGTAAAAAGTGCCCGGCTTGCCGTTTCGAAAAATGTCTTCAAAAAGGTATGAAATTAGAAGCAATACGTGAAGATCGCACCAGAGGAGGACGTTCTACATACCAATGTTCCTACACATTGCCGAATTCTCTAATGAGTCCAATTCTAACACCAGATCAGCAACAAAATACAGCACAAAGCTTAATAAATGCTCAAACACAACAGCAACAGTCGCAGTCTCAAATTCAACAGATGCCGCAACAACCGCAACCACCACCGCAACAGCAACAACGTTTAGTCGCACCTTTGCAGAGTAGTTACAACAGCACTTCCAATGCCAACGGTTATGTTCCGGGACTAGGATCCAATATTAAAACTGAACATTCGGTAATCGCTCCTCCTGCCTTGAACAATATTAATTTGAATTCTAGTTCACGCACTCTCATTCTAAACTCCTCTTCTTCCGCTGGTGACAACGATATACACGACAGCAGTATTCCTACTCTTTTACAAGAAATTATGGACGTGGAACATCTTTGGCAATACACAGTTGCTGAATTGGCGCGACTCAATCAACCGCTGATTTCACCCCCTTCGAGTTCAACTTCTTCAAACACCGTTTCCACAAATGTAGCAACACCGAGTCAAATGACCAATCCACTGCTGGCCAGTGCTGGCCTCTCATCCTCCACCAACCCTGATTTAATAGCACATCTTTGCAAAGTAGCTGACCATCGTTTATATAAAATTGTCAAATGGTGTAAAAGTTTGCCGCTATTCAAAAATATATCGATTGACGACCAAATATGCCTGCTAATCAATTCCTGGTGTGAGCTTTTGTTGTTCTCTTGCTGCTATCGGTCCATAGATACACCTGGAGAAATTAAAATGTCACAAGGTAAAACTGTTAACTTGGCTCAAGCAAAATTAACTGGTTTTCAGACCTGCATTGAAAGAATGCTGAATCTGGCAGATCATTTAAGACGTTTAAGGGTTGACCGCTACGAATATGTGGCCATGAAAGTGATAGTATTATTGCAATCTGACACATCAGAATTGCAAGAACCCGTAAAGGTTCGAGAATGTCAAGAGAAAGCTTTGCAAAGCTTACAAGCTTACACTTTGGCTCATTATCCGGATACTCCTTCCAAATTTGGTGAATTACTTTTACGTATACCCGATTTGCAACGAACGTGTCAATTGGGTAAAGAAATGCTTTCTATTAAATCTCGTGATGGTGGTGATTTTAATTTATTAATGGAGCTTTTAAGAGGAGAACATTGA
Protein Sequence: MSNIKTENASGLAIVNTSSATATSGSGNSLFQLPVNMSNHIMTDRTSSIITSTTTTNRNISVTNIKCEVDIDVATSTASSGNTVSIGFYNGARVANCTTGLGIRIPVTKAEDSDSETELTNIENLKVNRRITSSSGNLGSGNHHNAPRPMSWEGELSENEDTTEAELMDTDTTMSNSAVLQPQSSATVIKSEVSTTTPSTTQTVKPEIEQIAVEVHHHTAANSGGMGSIYHPKLKLAPTQSDPINLKYEPPDHSGLNNSPLLARQKSSTALTHLPANPSPDSAIHSIYTHSSPSQSPLTSRHAPYTPSLSRNNSDASHSSCYSYSSEFSPTHSPIQGRHPAPHVVYGSYNGSTPGNMHHSTLLYRPISTTANSTASANKLEMVGNEVQNLSMDANGSTSASSGPFSITTDVNGLPTSPAAGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCVRGGPCVVSITTRKKCPACRFEKCLQKGMKLEAIREDRTRGGRSTYQCSYTLPNSLMSPILTPDQQQNTAQSLINAQTQQQQSQSQIQQMPQQPQPPPQQQQRLVAPLQSSYNSTSNANGYVPGLGSNIKTEHSVIAPPALNNINLNSSSRTLILNSSSSAGDNDIHDSSIPTLLQEIMDVEHLWQYTVAELARLNQPLISPPSSSTSSNTVSTNVATPSQMTNPLLASAGLSSSTNPDLIAHLCKVADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCYRSIDTPGEIKMSQGKTVNLAQAKLTGFQTCIERMLNLADHLRRLRVDRYEYVAMKVIVLLQSDTSELQEPVKVRECQEKALQSLQAYTLAHYPDTPSKFGELLLRIPDLQRTCQLGKEMLSIKSRDGGDFNLLMELLRGEH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00749017;
90% Identity: iTF_00747508;
80% Identity: iTF_00748282;