Gmel011976.1


Basic Information
Transcription Factor Domain
Sequence Information
Similar Transcription Factors

Basic Information

Insect
Galleria mellonella
Gene Symbol
-
Assembly
GCA_958496185.1
Location
OY292295.1:6201340-6202530[-]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 1.8e-14 6.1e-12 46.1 0.0 4 108 39 141 37 143 0.91

Sequence Information

Coding Sequence
ATGACAGTGGTAACAAATCCAGCGTGTACCACGCAGTCTGACGACGAGATAGAGTCGGGGCACGAGAGCATATCTGGCGGAGAGTGTGGGCTTATGCTCGATGAAAACGCGCGATTATACGATAACGAGAAACAAAGTGATATCATTTTCGTAGCCGGTATTAACGGCGACACCTGGAGGTATCCAGGCCATCGACGGGTTTTAGCCGCTACAAGCCCTGTTTTCGCAGCTTTACTTTCTGCTAAAACTGATGTAATCATCGTTGATTATGTCGATCGTCGTGGTTTTGAGCAGCTACTCCGATATCACTATTGTGAACCAACGCAGCTCAATTCTGTGGCAACTGCACGGTGTGCTCTCGATGCGGCATACAAGTTCCTTTGCCCGCCCCTTGCGGAACGCTGTGCTCGACGTCTCGATGAGATGTTAGATGCAGGTGTTGCTTTAGAAATATTGAGGGATCTACGATTTCTATGTGCAAGATTACCTGGAGCCGCATCAGCACCACCTCTTCCAGCACTATCTGATGACGCCGCTGCAAGATCACTAGCACAGTGTTCACGTTGGTGTGATTCTCTAGCTCATAATGCACTTCTTGTGTTAGACAACGATGCCGACGCGGCTCTTACTGATGAACGACTTGAAGATCTCACATACGAAGATCTAGCTCTGATTGTGAAACGGGATACATTGCGAGTATCTAATGAACTTGTTTTAGTCGAAGCACTAACACGATGGAGTACCGCTGCTTGCAAACGTACCAAACGGGAACTGACGTCGAGTAACAAACGTGTAGCACTTGGCGAATTAGCATACTGCCCTCGATACCTTCTGTTATCGGGCGAAGAGTTAGATAGAGCTTTGGAATTGGAATTATTAGAACCAATGGAGCGGGCTTTAGTTACTGCAAGAGCTAAAAAGCTGTCAGCACCTGTTCCTGTGGGTGCTGAACAGGAGGCATTGCTGCGTAGATGGGCACGACCGCGGCCCAAGGAGCCAGCTGCATTGCCTGTACACTTAAGTTCACGCTCAGAGCCTCTTCCGGAACCACAGCCGAGCAAATTATGTGCGCGCCGTTCTAAACGGCCAAAACAGCCAAGTTTTGCGCCTGAAGAGAAACGCAAGAAACCTGGTTGCTGTGCGCGTTTCGGCGAAGGCCTTTTGAGAGCTTTTATCTGTTTATTTGACTGA
Protein Sequence
MTVVTNPACTTQSDDEIESGHESISGGECGLMLDENARLYDNEKQSDIIFVAGINGDTWRYPGHRRVLAATSPVFAALLSAKTDVIIVDYVDRRGFEQLLRYHYCEPTQLNSVATARCALDAAYKFLCPPLAERCARRLDEMLDAGVALEILRDLRFLCARLPGAASAPPLPALSDDAAARSLAQCSRWCDSLAHNALLVLDNDADAALTDERLEDLTYEDLALIVKRDTLRVSNELVLVEALTRWSTAACKRTKRELTSSNKRVALGELAYCPRYLLLSGEELDRALELELLEPMERALVTARAKKLSAPVPVGAEQEALLRRWARPRPKEPAALPVHLSSRSEPLPEPQPSKLCARRSKRPKQPSFAPEEKRKKPGCCARFGEGLLRAFICLFD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00345986; iTF_00787843; iTF_00290866; iTF_00835779; iTF_01444065; iTF_00834823; iTF_00836755; iTF_00837750; iTF_00445381; iTF_01085569; iTF_01285729; iTF_00447426; iTF_00623010; iTF_00822146; iTF_01487874; iTF_00677827; iTF_01377667; iTF_00157380; iTF_00282596; iTF_00383877; iTF_01064837; iTF_01197957; iTF_00712104; iTF_01339112; iTF_00786153; iTF_00928879; iTF_00281552; iTF_00177361; iTF_01063922; iTF_01441266; iTF_00784564; iTF_00785366; iTF_01062999; iTF_01340407; iTF_00783704; iTF_00794872; iTF_01492184; iTF_01332985; iTF_00273786; iTF_01152346; iTF_00274587; iTF_01425275; iTF_00446396; iTF_01084445; iTF_01119549; iTF_00685630; iTF_01029438; iTF_00040063; iTF_00173248; iTF_01062048; iTF_01360869; iTF_00441699; iTF_00824039; iTF_00869833; iTF_00709429; iTF_01143242; iTF_01141820; iTF_01155530; iTF_01143969; iTF_01148963; iTF_01495171; iTF_01148228; iTF_01496709; iTF_01495910; iTF_01139079; iTF_01141064; iTF_01156808; iTF_00204490; iTF_01149740; iTF_01144685; iTF_01337872; iTF_00249841; iTF_01145393; iTF_01130162; iTF_01158002; iTF_00180629; iTF_01494454; iTF_01146551; iTF_01402841; iTF_01154266; iTF_01159578; iTF_00840412; iTF_00923005; iTF_01115837; iTF_00197502; iTF_01142526; iTF_00856000; iTF_01386892; iTF_01341478; iTF_01385969; iTF_01387772; iTF_01388672; iTF_00208077; iTF_00209049; iTF_01176301; iTF_00172014; iTF_00823199; iTF_01464340; iTF_00833249; iTF_01548020; iTF_01317473; iTF_00114251; iTF_00112659; iTF_00113461; iTF_01401462; iTF_00405176; iTF_00909035; iTF_00844568; iTF_00111842; iTF_01501348; iTF_01118503; iTF_01117531; iTF_01316537; iTF_01504057; iTF_00008188; iTF_00674460; iTF_00994520; iTF_01436288;
90% Identity
iTF_00008188;
80% Identity
-