Basic Information

Insect: Galeopsomyia nigrocyanea
Gene Symbol: Rfx2
Assembly: GCA_035047105.1
Location: JAWWMK010000001.1:5804137-5814064[-]

Transcription Factor Domain

TF Family: RFX
Domain: RFX domain
PFAM: PF02257
TF Group: Basic Domians group
Description: RFX is a regulatory factor which binds to the X box of MHC class II genes and is essential for their expression. The DNA-binding domain of RFX is the central domain of the protein and binds ssDNA as either a monomer or homodimer [1]. It recognize X-boxes (DNA of the sequence 5'-GTNRCC(0-3N)RGYAAC-3', where N is any nucleotide, R is a purine and Y is a pyrimidine) using a highly conserved 76-residue DNA-binding domain (DBD) [2].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 2.6e-37 2.6e-33 115.6 0.0 2 78 403 479 402 480 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	2.6e-37	2.6e-33	115.6	0.0	2	78	403	479	402	480	0.97

Sequence Information

Coding Sequence: ATGAGCAACTGGCAGGAAGACGACGACACTTCGTTCGAAGAGTTTCTTCACAACgagcaaattttcatcattccCGATACACCCGAGAGCGACACGACTGTCGTTGATCACCTGCAGAACGACGATTCTTATTTGCTCCTTGAAAATGGTGATTTCGAGAATCATGAGGCATCCCAGCAGAAACGGAGAGGCAGAAGTGGCGGTGATACGTTGGAAGCTGAGAGTGGCAAGGGAGTTATTGCCATGACTACCACAGGAGCCCAGTATACTCTAGCAACATCCACTGGGGCTGGAAATGCTGGCGGGGGCAGCTCAGCGGTGGGGGATGAAAAGCCAAGCGTCGTTGTCGTCACCACTTCTAATTCCAATGGCAGTGCCAGTGCTGCTCAGTCACAAGCCACTCGCACACAACAACTGATCACTGTTGTCACCAGTGATCCATCCAGTCCTAATAGCTTACAGCCTATTCAGtTACTGGTGCAAGATTCTCTGGATGCTGCAGGAGATTCATCAAATGGATCTTCCAGTACTCAGGCACATGTAACAGCACAAGTAGTTGTCAACACAACGCACTCTGGTCAGCATACTCTAGTGGATTCTGACGCTGTACCTACCTCTGCTGGCACAATAGTCAGTGGCTCGCCTCACTACATCACTGTTACAGGCACCAACGAGCCTTCGACATACGCGTCCCTCACGACGGCTGTAGTGCCAGGAGACGCCGACGCCGTGGGGTCCGAGTCGGTTGCTCATCCTACCTTTGTACAGTATGTCGAGGGAGATGGATCCACGTATATACCGGCGAATGGACAGATgacATATCCAGTGTACGCTGTGGGCGAGGCGGGAACAATGTACACTCCCGCCACGAACCAATATTACGCTTCCGCGTCCACGCCGGTCACTTATGCACAAGTCACAGGCTCAACTGCGACGGGTCAATTGTTGTCGCAAGGCAACGGGACTTACTTGATACAGCAGAGTGTTGTCGAAGGTGATCCGACGCATACGCTCATATCGGCTGCAACAGCTCGCGCCAGTCCTCAAACTGAAAGTGCCGAAGCAGTGGTtagcggtggtggcggtgcGTACTTGATAAGTGGCAATTCGGCGAGCGCGCCACAGCCGCAAGCTCAGTCGACGCAGTCGACGGTCGAGGATGCGGCCACTGCCGCGGCTAACATGACCCACGCGACTAGGGTGTCCCAGGCCACCGTACAATGGCTGTTGGAAAATTACGAGACAGCCGATGGAGTGTCATTACCGCGATCGACGCTTTACAATCACTACCTCCGTCACTGTTCCGACAACAAATTGGATCCGGTGAACGCAGCTAGCTTTGGTAAACTCATTCGTTCTGTATTTCTGGGTCTACGCACAAGACGCCTTGGAACTCGTGGCAACTCAAAGTACCATTACTACGGTATCCGAGTGAAGCCAAGCTCTCCGCTGGTGCATCTGAACGAGGACGGCACGTCGCGGCAGCAACCAACGTCGAATTCGCAAGCGAACAAACGAGTGAAGTTCGTGAATCAAAAGCAGTCGGACACGGTTTACGAGTCCAACAACGCGCAAATGAACAACAACGCGACGAACGTCTCGCCCAATGCAACGTCACCCCAGTATCATCAGTACCTCGGCGACGCGAGTTGCGCGATACCCGAGTTTCCCGAAATCATCGTTCACGGCTCTCTTCACGAAGACTGCACTCTTGAGGATATCGATACCTTCAGGAGTATTTACAGAGAGCACTGTGAAGCTTTTCTCGACGCTGTGCTGAACTTTGAGTTCGCTACTATTGAAAGTCTCTGGCGTGAATTTTGGCGCAGTCAGGATAACAATAATGGAGACGAGTGCGAGGAGGAGAAGTATCTCTCGAAGACTAAACTTTATCAACTGTGCAAGTGCCCTGAAGTTCAAGAATTTATCAGGAGAGTCGACTACACGTTTTATCAGAATCTCGTTGAAGTGCTTATGCCTGATGTTTTGAGGCCTATACCAAGTCCCTTAACCCAGTCCATTAGAAATTTTGCTAAAGGCTTAGAATCGTGGCTGACGTCTGCCATGAATGACTGTCCCGAAGAAATGATGCAGATAAAGttaaCTGCCGTATCAGCGTTTGCTCAAACTCTGCGAAGATACACATCCCTCAACCACTTGGCGCAAGCTGCAAGAGCCGTACTGCAAAATAACAGTCAAATTAATCAAATGCTGGCGGATCTTAACAGAGTTGATTTCCACAATGTACAGGAGCagGCATCCTGGGTTTGCCAGTGTGACTATGCAGTTGTGCAGCGCCTCGAGGCTGATTTCAAATTAACACTTCAGCAGCAAAACTCGTTGGAACAATGGGCCGTTTGGTTGAAGGGAGTGGTGACGCAGGTGCTTCAGCCTTACGAGGGCAAACAAACGTTTGCCAAAGCAGCACGACAGTTCCTGCTCAAGTGGTCTTTCTACAGTTCGATGGTCATTAGGGATTTGACTCTGCGTAGTGCCGCGAGCTTTGGCTCATTTCATCTGATTCGGTTACTCTACGACGAATACATGTTCTACCTGATTGAACACCAAGTTGCCATCTCTACGGGTACCACGCCGATTGCCGTTATGGGAGATAAGAGCCAGAATGGTCCCATTATGAGTGAATTTGAATCAAACGGAGatGCATCAAATATTAATCCATCGAAACGAATGAAAATGAGCTAA
Protein Sequence: MSNWQEDDDTSFEEFLHNEQIFIIPDTPESDTTVVDHLQNDDSYLLLENGDFENHEASQQKRRGRSGGDTLEAESGKGVIAMTTTGAQYTLATSTGAGNAGGGSSAVGDEKPSVVVVTTSNSNGSASAAQSQATRTQQLITVVTSDPSSPNSLQPIQLLVQDSLDAAGDSSNGSSSTQAHVTAQVVVNTTHSGQHTLVDSDAVPTSAGTIVSGSPHYITVTGTNEPSTYASLTTAVVPGDADAVGSESVAHPTFVQYVEGDGSTYIPANGQMTYPVYAVGEAGTMYTPATNQYYASASTPVTYAQVTGSTATGQLLSQGNGTYLIQQSVVEGDPTHTLISAATARASPQTESAEAVVSGGGGAYLISGNSASAPQPQAQSTQSTVEDAATAAANMTHATRVSQATVQWLLENYETADGVSLPRSTLYNHYLRHCSDNKLDPVNAASFGKLIRSVFLGLRTRRLGTRGNSKYHYYGIRVKPSSPLVHLNEDGTSRQQPTSNSQANKRVKFVNQKQSDTVYESNNAQMNNNATNVSPNATSPQYHQYLGDASCAIPEFPEIIVHGSLHEDCTLEDIDTFRSIYREHCEAFLDAVLNFEFATIESLWREFWRSQDNNNGDECEEEKYLSKTKLYQLCKCPEVQEFIRRVDYTFYQNLVEVLMPDVLRPIPSPLTQSIRNFAKGLESWLTSAMNDCPEEMMQIKLTAVSAFAQTLRRYTSLNHLAQAARAVLQNNSQINQMLADLNRVDFHNVQEQASWVCQCDYAVVQRLEADFKLTLQQQNSLEQWAVWLKGVVTQVLQPYEGKQTFAKAARQFLLKWSFYSSMVIRDLTLRSAASFGSFHLIRLLYDEYMFYLIEHQVAISTGTTPIAVMGDKSQNGPIMSEFESNGDASNINPSKRMKMS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00254817;
90% Identity: iTF_00326105;
80% Identity: -