Basic Information

Insect: Formica exsecta
Gene Symbol: znf423
Assembly: GCA_003651465.1
Location: NW:130866-219928[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 22 1.6e-05 0.0011 18.7 1.7 1 23 143 165 143 165 0.98

2 22 0.038 2.5 8.1 4.6 1 23 171 193 171 193 0.98

3 22 1.9e-06 0.00013 21.6 2.3 1 23 199 221 199 221 0.99

4 22 5e-05 0.0034 17.1 0.1 1 23 227 249 227 249 0.99

5 22 0.00019 0.013 15.3 1.1 1 23 415 438 415 438 0.97

6 22 0.56 37 4.4 0.1 2 23 449 471 448 471 0.88

7 22 0.33 22 5.1 0.1 3 23 540 560 539 560 0.97

8 22 0.0036 0.24 11.3 0.4 3 23 577 597 575 597 0.95

9 22 0.0025 0.17 11.8 0.4 1 23 606 629 606 629 0.93

10 22 3 2e+02 2.1 0.2 1 23 634 657 634 657 0.91

11 22 0.24 16 5.5 0.0 5 23 687 706 685 706 0.93

12 22 2.3 1.5e+02 2.5 2.2 2 23 737 758 737 758 0.96

13 22 0.0041 0.28 11.1 0.1 1 23 763 786 763 787 0.94

14 22 2.7 1.8e+02 2.2 0.1 2 23 850 873 849 873 0.81

15 22 9.9e-05 0.0067 16.2 0.9 2 23 891 913 890 913 0.96

16 22 0.36 24 5.0 2.6 1 23 922 945 922 945 0.92

17 22 0.73 49 4.0 1.0 2 23 953 974 952 974 0.96

18 22 0.0016 0.11 12.3 0.1 2 23 1137 1159 1136 1159 0.96

19 22 0.11 7.3 6.6 0.2 1 23 1171 1194 1171 1194 0.95

20 22 0.21 14 5.7 0.2 2 23 1207 1228 1206 1228 0.95

21 22 0.28 19 5.3 0.2 2 23 1237 1259 1236 1259 0.93

22 22 0.061 4.1 7.4 3.0 1 23 1266 1289 1266 1289 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	22	1.6e-05	0.0011	18.7	1.7	1	23	143	165	143	165	0.98
2	22	0.038	2.5	8.1	4.6	1	23	171	193	171	193	0.98
3	22	1.9e-06	0.00013	21.6	2.3	1	23	199	221	199	221	0.99
4	22	5e-05	0.0034	17.1	0.1	1	23	227	249	227	249	0.99
5	22	0.00019	0.013	15.3	1.1	1	23	415	438	415	438	0.97
6	22	0.56	37	4.4	0.1	2	23	449	471	448	471	0.88
7	22	0.33	22	5.1	0.1	3	23	540	560	539	560	0.97
8	22	0.0036	0.24	11.3	0.4	3	23	577	597	575	597	0.95
9	22	0.0025	0.17	11.8	0.4	1	23	606	629	606	629	0.93
10	22	3	2e+02	2.1	0.2	1	23	634	657	634	657	0.91
11	22	0.24	16	5.5	0.0	5	23	687	706	685	706	0.93
12	22	2.3	1.5e+02	2.5	2.2	2	23	737	758	737	758	0.96
13	22	0.0041	0.28	11.1	0.1	1	23	763	786	763	787	0.94
14	22	2.7	1.8e+02	2.2	0.1	2	23	850	873	849	873	0.81
15	22	9.9e-05	0.0067	16.2	0.9	2	23	891	913	890	913	0.96
16	22	0.36	24	5.0	2.6	1	23	922	945	922	945	0.92
17	22	0.73	49	4.0	1.0	2	23	953	974	952	974	0.96
18	22	0.0016	0.11	12.3	0.1	2	23	1137	1159	1136	1159	0.96
19	22	0.11	7.3	6.6	0.2	1	23	1171	1194	1171	1194	0.95
20	22	0.21	14	5.7	0.2	2	23	1207	1228	1206	1228	0.95
21	22	0.28	19	5.3	0.2	2	23	1237	1259	1236	1259	0.93
22	22	0.061	4.1	7.4	3.0	1	23	1266	1289	1266	1289	0.97

Sequence Information

Coding Sequence: ATGTCCAGGAGGAAGCAGGCGAAGCCACGATCTCTCAAACGGGACGAAGAGTGGGACGACGGCAACGAGCAGAATGTCCTGGAGGCGGCCGAACAGGATAACGAAACGACGGCGATTAAGCAGGACGacgaagaggaggaggaagaggaggagttGCAACGAGCATTCAGCCGTCAATCAGAAGATTACTTGCAAGATGGCAGGCCAACTTCCGTTCAAGGTCCTGATCTGGAGAATCAGAACAGCCTCGACAGCGaAGCTCTAGGAACCGGAAGTTCCTCGTGGCATAGCGAGGATGGCGGGCCCAATTCCCGCCGCGGTGGCGAGACACCGTCCTCCTGCGCGACTCCAACATCGGCGAGTTTCCCGTCGGAGCCTGAGGTCGACACCGACGTCAATCCCGACGGCACCAATCCCGCCGCCCCCTATCCCTGCCAATTCTGCGACAGGAAGTTTCCGCGTCTTAGCTATCTGAAGAAGCACGAACAGAGTCACGGTGATCAGATGCCGTATCAGTGCAGTTGGTGCAACAGACTGTTCAAGCACAAGCGTAGCCGCGATCGTCACGTAAAGCTGCACACTGGGGACAGGCGATATCGCTGCTCGAAATGTGAGGCTGCCTTCTCTAGGAGCGATCACCTGAAGATCCACTTGAAAACGCATGACACCCAGAGGCCTTATCAATGCACGGCTTGCACGAGAGGCTACAGTACAGCCGCGGCTTTAACGGCGCACATGCAGTCTCACAAGAAACATcaatcatcgtcgtcgtctcaATCGGCCGGTCTCAAGCTTCAGGACGTCGACTATGGTAGAAGAAGCGTATCCTCGCACAGCACGTCGTCACCGCCGGtaccgtcgtcgccgtcgccgtcatTGAATCTCAGTCTGAACCCGAGGAACGTCCTGAAGACGTCGCAGGGCACCGGCAGTGCCTCCACCACTCCGGTTCTCAGCTCGCCCCTGAAACTCACCTGCATGTACTGCACCCGGGACTCGTTCAGCTGCATGCAGCAGCTGCAGATGCACGTGCACACGATGCACCAGGCGATCCTGAGTGGCGCGGAAGGTCCAGCTCGGCCGCCATCGCCGAGCAGAACGTCCAGCGAGCAGCAGACGACTGTCTGCAAGCCGCTGGATCGTCAGGACGTCACGAAGGAATCGCGACTGGATCGCAAGTACCCGACGTCCGAGGACCGAGGCGACAGGTCGGCTGTCGAGCGGGAGCATTACGAGAACGGGTTCACCTGCAATCAGTGCACCATGAAGTTCTCTACGTTGACCCTCCTACGCGATCATTTGTTGTCGATACACCGAATCGACGGTTTTGGCGCGGCGATGATGATGTGTCCCTTGTGCAGTATACCGTGTTCCTCGGCGGCTTCCTACGCCGAGCACTACGTCCTTCAGCACTGTGAGAATCGCCGACCGGCGCCGACGCACGCTATAGATTACGGGGAAACGAAGCTGAACGGCGGCATTTACGACGGTACCGCGAGGGATCCCTCCCGGATATCGAGAACTCGGGACGCGCCGGAAGCCGCTGATCTCACGAATAAGCACTCGACCAGATCTTCCTCGGATACCGCTGGCAGTTACACTGCTGATACTCTGCTATGCGGCCAATGCGGTGCCGCATTAAAAGACTTCGAATCCTTCCGCGAGCATGTGGCGCGACACTTGCAGGCCGACCACCGTAACCAGGAGATGTCCGGCAGACAACATCTATGTCCCAAATGCGAAGCCATCTTCTCGGACCGCGAGGATATGCTGGCCCACCTGACCAAGCATTATCTGGGCCAGGTCAGCAAAGAGTACGCCTGCAGTGCCTGCAAAAAGCTCTATCCGCATCCAGATCAGCTTCAGAGGCACCTTTTGGATGTGCACGCGCATCATCTGTATCGTTGCGCTCTGTGTCGGGACACCTTCGACTCCAGAGTAGCAATACAGGTGCATTTTGCGGTGAAACACAGCCAAGAGTGCCGGGTCTACCGGTGCAGCACGTGCGCCGTGTCCAACAATGAGAACTCGCCGGGAGGAAACGTGACGACTTCTGGCGAATGTAGGAGCTTCTTCAGGACCGAGGCCGAATTGGCGGCGCACGTGCGTAGTGTGCACGCGCCTCCACCCGCTGTCTCTCTGATGAATAGCAGCCCGGTGGGTGCTGCGAGGAGCCCGGCCTCGACGCCCGGTGGTGGTATCGCGGCGCGTTGTTTCTTCTGCGGGATTTGCTGCGGTTCAGATCTCGAACTCCAGCTTCATTTGGCCAGCCACTCGACCAATCTCTACAGATGTCCCATCTGCCGGGAAGGATTCGCGGTGGAGTTTCTCTTGGACCGACACATCGCCCAGGCTCATCACGCCACCCAGGACCATCAGGTACCATCCGTCAGAAGTAACTCGAGAGAGAACGGGCGCGTTCATCGAACGGCTAGAAATCAGGAAGAAACGAAGTCTCTGAAGAGACGTTCACCAGCATCGAGTAACAACAATTCCCTGAATCAGCGCGACAACAACAAACGTGCAAACTATGGCACTTCCGGACAGCAGTGCGAGCTCTGCGAACGCGGCGAATTTGCGAACGAGGCCGAGCTGCAAGCACACAAGAAACTGACTCACCAAACGCCTCCTAAACTGTCCAGTAAAAGTTTATCTACCTTGAATACCCTGACGTGCGGTTATTGCGGCGAGGTTTGTCGTTCGCGAAACGAATTAGAGTCGCACACGAGGATCCAACATGCGTCCAACGAGCCCGGCGGACGTCACAAATGCAACATCTGCGACGAGGTATGCTTGTCCAGCACGACTTTGGCCGAACACAAGCTCCAGAAGCACTGCAAGATACAACTGAGCGATACGTGCGTGGTGTGTCGTGGTTGCCTGACCTCGGAGAGTCAATTCCTGGATCACGTGCAAAGGCATAGCTTGGAAAACGTGGACCCGCAACAACGATTGGACAACTCTTTACCTCATTTACCCGCCCCGTGCGTTGTTTGCCGGCAGACGCTGATCAGCGAATTAGAGTGTCGTTTGCATGCACGGCATCATCTACGGACGTCTTCAGGATCGCGCAGCGCCGTTTCTAGTCCGACCAGTCCCGGTGGCGGCAAAACTCAGAGCCAAGGTTGCTGTCTCTGTTTGCGCGATTTTGCTGCCGATGATTTCGTCAGTCTGCCACCCAATCCTGCCAGTACGAGTGGACAACCACTCAAGGTCTGCAAAACCTGCTACATGCGACATTCTCAGGGATTGCCTATCCTGAACTCGACGACCTATGAGCGGGCCAAGTACGATACGACCTGGTTCGCAAGCAAGAATGGTCAATGGGATAGTTCCAAGGACAAATGGGATGACAGAGGACTCAATGTAGAGAATCGATCCAAAAATGAAGGAAACACGGATAAAAAACGCTGTGAGGAGTGCGGGGTGAAATTCGAAGATCCTGAAGAGGCGGAGAAACACAGAATCACAGAACATGAAAAGATTAGCACTAGTGGTTCGAAACCCTCCTATACATGTATACAGTGTCAGGTATCATTTCCAACCGAAGCCAAAATTCAGCAACATGTGAGAAAGGAACATCTGGAAACATCCAGGAGAGCTTCCTTGGAAGCCTTGCGATGTCATTTGTGCTCATTTGAAGCTGCCAGTCCTATGCAATTGCAAATTCACTTAATAGAACATACTTTTGTTGGCTGCGCTGCGCTCAGCTGTTACCTCTGTCAGTCGCTTTTTACAACTCCTATTGGTCTTCAGAGTCACCTGCTACAGGAACACGGTCTGGGCGCGCGACCTTACGATTGCCGCAAGTGCACGCTCAAGTTCTTCTTCAACGCGGAGCTAGACCATCACATATTGACTTTCCATCGTCCGAGGGATGAGATTCATCCTTCGTCAGTCGAGAATGCTCGCGAGATGAAGAATCGCGAGCCCGACGGCGGTGTAACGGTGAAGGAGGAAGTGATGCAAGGTGGcaaagaagaggaggaggaggaggaggaagtgAACGTGGACGATCAGATAGGACAGGAGGAACATGATGAAGCTAAACGAGAGGAGCAGAAGTTGAAGACGGAAGTAGATATCGAGACGACATCCAACAAAATGGAATCGTGA
Protein Sequence: MSRRKQAKPRSLKRDEEWDDGNEQNVLEAAEQDNETTAIKQDDEEEEEEEELQRAFSRQSEDYLQDGRPTSVQGPDLENQNSLDSEALGTGSSSWHSEDGGPNSRRGGETPSSCATPTSASFPSEPEVDTDVNPDGTNPAAPYPCQFCDRKFPRLSYLKKHEQSHGDQMPYQCSWCNRLFKHKRSRDRHVKLHTGDRRYRCSKCEAAFSRSDHLKIHLKTHDTQRPYQCTACTRGYSTAAALTAHMQSHKKHQSSSSSQSAGLKLQDVDYGRRSVSSHSTSSPPVPSSPSPSLNLSLNPRNVLKTSQGTGSASTTPVLSSPLKLTCMYCTRDSFSCMQQLQMHVHTMHQAILSGAEGPARPPSPSRTSSEQQTTVCKPLDRQDVTKESRLDRKYPTSEDRGDRSAVEREHYENGFTCNQCTMKFSTLTLLRDHLLSIHRIDGFGAAMMMCPLCSIPCSSAASYAEHYVLQHCENRRPAPTHAIDYGETKLNGGIYDGTARDPSRISRTRDAPEAADLTNKHSTRSSSDTAGSYTADTLLCGQCGAALKDFESFREHVARHLQADHRNQEMSGRQHLCPKCEAIFSDREDMLAHLTKHYLGQVSKEYACSACKKLYPHPDQLQRHLLDVHAHHLYRCALCRDTFDSRVAIQVHFAVKHSQECRVYRCSTCAVSNNENSPGGNVTTSGECRSFFRTEAELAAHVRSVHAPPPAVSLMNSSPVGAARSPASTPGGGIAARCFFCGICCGSDLELQLHLASHSTNLYRCPICREGFAVEFLLDRHIAQAHHATQDHQVPSVRSNSRENGRVHRTARNQEETKSLKRRSPASSNNNSLNQRDNNKRANYGTSGQQCELCERGEFANEAELQAHKKLTHQTPPKLSSKSLSTLNTLTCGYCGEVCRSRNELESHTRIQHASNEPGGRHKCNICDEVCLSSTTLAEHKLQKHCKIQLSDTCVVCRGCLTSESQFLDHVQRHSLENVDPQQRLDNSLPHLPAPCVVCRQTLISELECRLHARHHLRTSSGSRSAVSSPTSPGGGKTQSQGCCLCLRDFAADDFVSLPPNPASTSGQPLKVCKTCYMRHSQGLPILNSTTYERAKYDTTWFASKNGQWDSSKDKWDDRGLNVENRSKNEGNTDKKRCEECGVKFEDPEEAEKHRITEHEKISTSGSKPSYTCIQCQVSFPTEAKIQQHVRKEHLETSRRASLEALRCHLCSFEAASPMQLQIHLIEHTFVGCAALSCYLCQSLFTTPIGLQSHLLQEHGLGARPYDCRKCTLKFFFNAELDHHILTFHRPRDEIHPSSVENAREMKNREPDGGVTVKEEVMQGGKEEEEEEEEVNVDDQIGQEEHDEAKREEQKLKTEVDIETTSNKMES

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01406753;
90% Identity: iTF_00868309;
80% Identity: -