Ebru025102.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Eurytoma brunniventris
Gene Symbol
PRDM5
Assembly
GCA_900475205.1
Location
UXGB01000222.1:80480-83738[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 17 0.0013 0.15 13.3 0.2 1 23 159 182 159 182 0.91
2 17 3.9 4.6e+02 2.3 2.0 3 23 193 214 192 214 0.94
3 17 0.43 50 5.3 1.9 1 15 220 234 220 241 0.80
4 17 2.8e-05 0.0032 18.5 0.3 1 23 252 275 252 275 0.95
5 17 0.0064 0.75 11.1 1.2 1 19 291 309 291 310 0.96
6 17 1.3e-05 0.0016 19.5 2.7 1 23 325 347 325 347 0.95
7 17 0.0004 0.047 14.9 0.1 1 23 353 375 353 375 0.97
8 17 0.00028 0.032 15.4 0.5 1 23 381 404 381 404 0.97
9 17 0.12 14 7.0 4.6 3 23 541 562 539 562 0.96
10 17 5.8e-06 0.00068 20.7 0.8 2 23 569 590 568 590 0.95
11 17 0.065 7.7 7.9 6.5 1 23 599 622 599 622 0.95
12 17 0.0045 0.53 11.6 3.0 1 23 628 650 628 650 0.96
13 17 9.8e-05 0.011 16.8 2.5 1 23 655 678 655 678 0.96
14 17 0.097 11 7.4 1.2 1 23 684 706 684 706 0.97
15 17 0.0012 0.14 13.4 4.4 1 23 710 733 710 733 0.96
16 17 0.033 3.9 8.8 0.8 3 23 741 761 740 761 0.98
17 17 3.3e-05 0.0039 18.3 1.2 1 23 767 790 767 790 0.95

Sequence Information

Coding Sequence
ATGCTACATCGCGAGGTCAAGCCAAGCACCTCGGCCACCACCACGACAGTACGAGGCAACGGCTGCAACGACGAGGAACCTGCCGATTCTGCACCTGTAACCAGATCTGCTAAAATTCGTTTCAGGGAATCACTGGGCAAGAGTAATCCAACACCGGAAGACGAGCCACCAGCGAAGAAGCCAAATCCCCAGAGTAAGTGTGCCCCGGATGCCGCGAGTCCCGAAACCCCGTCGGTCGCGAAGAAATACTTCCTGCGCGCTACGTCGTCGAAGGATGCAGCGAAGGGAGAGCAGGGCGGCGCGGAGGTCCCCGACGACGTGGACGACCTGATGACGCTGCTGGCGATGTACAAGGAGCTACCGGACGGCGGCTTCGTGTGTCAGCTGTGCGAGAGCGCGGAGGGCGTGAACGTGCTGCAGGACAAGCCGCACGTCGTGCGCCACGTAATCCGATCCCACGGCTTCAGCCATGCCCACGAGTGCCCCAGCTGCCCGAGCAGCTTCAAGCGGGAGTCGTGGCTGGCGAGCCACCTCGACGCGCTGCACAAGACCGAGAAGCTCGAGCGGTACGTCGACTGCGCGAGGTGCTCGCACCGCAGCAAGGACGAGACGCTGCTCAGGCTCCACGTGCTCAGGAAGCACGTGGCCTTCTGCCGCTACGTCTGCGGCTGCTGCGGCAAGTGCTTCAGGACCTCGGCGGCCAAGGGCGAGCACGAGCGCCTCTCCGGCTTCCGGAAGAAACCAAAGATCAAGTTCGAGTGCGACAAGTGCCAGATCGTAACCAAGACTAAAGACGATTTGGAGAGGCACATCAAAGACGTCCATTCCGGGTGCCACTTCCGAATGATCTACAGGTCGTCGAAGCTGCAGTACAAGTGCCTGATATGCAGCAAGATATTCGTCTCGAAGAAGTCCTTCCACGAGCACGCGCCCTGCCAGGACAGCCCGGCCGAGGGCAACGAGGTGGAGGGCTTCCTGTGCAGCCAGTGCGGCAAGCGGCTGTCGAGCAAGGACCACCTGAAGAAGCACGCGCGCGTCCACAGCGGCGAGCGACCCTACCCCTGCCCGGAGTGCGGCCAGACCTTCGCCCTGCGCAACACCATGCGCATCCACGCGCTCTCGCACTGCGGCATCAAGCCTTACGTCTGCGAGATCTGCCGTTTCAACTACTCGCAGCGCTCGGCCCTCATGATACACTGGAAGAGCAAGCACAAGGAcatgccgccgccgccgcccgtcGAGATCCACCAGTACTTCGACGCGAACGGCCAGCTGCTCTCCATgAAATACAATTCTCGTTTGAGGAATAAAAGTTCCAACTCCCGGATAAGAGTACGCACAACGTCAGAACTTACCAATACTCCACAAGTCTTGGGGACCAGATCGCCATCGCCCcgagttttgaaaaaagcgACAAAGGCCATGcctaaaaaaactaaacaagTCACCTCCAAGAGAAAAAGCTCGATTTCAACAGCTAAATGTCAGGAGGAAGCGACCGCCGAAGTTTCTGCACCTCCAGCTAAAAAGGCAAAAGTCGACGATTTGCCAAAGCAAGAAAGTCAAccgaaagaagaagaaaagttcgattttaaaaagttaaaaggcGGCGGTTTTGGTTGTACACTGTGCTTCCAGAAGTTCAGCCACCGTTACAAGGTGAAGCAGCACCTGAAGTTGAAGCACAAGCCGCGCGAGATTATCACTTGCGCCGACTGCGGCAAAAAATTCAAGTCCAAATACCAATTAAACATGCACGCGAATCAGCATCGCGAGAACAGTAACGACTATCTTTTCTGCTGCGATAAATGCGACTACCGTGCCAAGTCTAAGCACTACCTAAAAACCCACGTGATTCGCAAGCACACCACCGAGTACAAATTCGAGTGCGCTCACTGCGACAAACGCTTCAAAATGAAGATGGACCTGAAGTTCCACCTGGGCACCCACGGAACCTCGCAGCACATGTGCGACGCCTGCGGCCGCATGTACTCGAGCCAGGACTCGCTCCACAAACACCGGCGCGTCGTCCACTTGAACGACTACAAATACCAGTGCGATATATGCCACCAGAAGCTACTGACGGAGGCGAACTACAAGAGTCACGTGGAGTCGCACAAAAACATGCACAGCTGCGACGAGTGCGACCTCAAGTTCACCAAGAAGTACTACGTGACGCGGCACAAGAAACGCGTGCACAAGGTGGAAAAGACGAATCTGTGCCGCGTGTGCGGCAAGGCGTTCGTCTGCATGGCGACGCTCAGGGTGCACTACCTGACTCACGTGAAGATCAAGCCGTATCTGTGCAACGTGTGCGGATACAGCTTCACCCAGCGATCTTCGATGATGCTGCACTGGAAGAGAAAACATCCGGACGCAGAGGAGCCACCTCCACCAGTGATACTTACCAATTTCTTTGAATCCATAGAGACCGAAGTCGATAAAATCGCCGAGAAGAACAACTTGACTGACAGTGGAGAGTGA
Protein Sequence
MLHREVKPSTSATTTTVRGNGCNDEEPADSAPVTRSAKIRFRESLGKSNPTPEDEPPAKKPNPQSKCAPDAASPETPSVAKKYFLRATSSKDAAKGEQGGAEVPDDVDDLMTLLAMYKELPDGGFVCQLCESAEGVNVLQDKPHVVRHVIRSHGFSHAHECPSCPSSFKRESWLASHLDALHKTEKLERYVDCARCSHRSKDETLLRLHVLRKHVAFCRYVCGCCGKCFRTSAAKGEHERLSGFRKKPKIKFECDKCQIVTKTKDDLERHIKDVHSGCHFRMIYRSSKLQYKCLICSKIFVSKKSFHEHAPCQDSPAEGNEVEGFLCSQCGKRLSSKDHLKKHARVHSGERPYPCPECGQTFALRNTMRIHALSHCGIKPYVCEICRFNYSQRSALMIHWKSKHKDMPPPPPVEIHQYFDANGQLLSMKYNSRLRNKSSNSRIRVRTTSELTNTPQVLGTRSPSPRVLKKATKAMPKKTKQVTSKRKSSISTAKCQEEATAEVSAPPAKKAKVDDLPKQESQPKEEEKFDFKKLKGGGFGCTLCFQKFSHRYKVKQHLKLKHKPREIITCADCGKKFKSKYQLNMHANQHRENSNDYLFCCDKCDYRAKSKHYLKTHVIRKHTTEYKFECAHCDKRFKMKMDLKFHLGTHGTSQHMCDACGRMYSSQDSLHKHRRVVHLNDYKYQCDICHQKLLTEANYKSHVESHKNMHSCDECDLKFTKKYYVTRHKKRVHKVEKTNLCRVCGKAFVCMATLRVHYLTHVKIKPYLCNVCGYSFTQRSSMMLHWKRKHPDAEEPPPPVILTNFFESIETEVDKIAEKNNLTDSGE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01380799;
90% Identity
iTF_00713123; iTF_00714597;
80% Identity
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