Ecal005229.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Eurytoma californica
Gene Symbol
PRDM5
Assembly
GCA_035586675.1
Location
JAXIUT010000021.1:18531674-18534931[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 17 0.0028 0.36 12.4 0.2 1 23 158 181 158 181 0.90
2 17 4.5 5.8e+02 2.3 2.3 3 23 192 213 191 213 0.95
3 17 0.14 19 7.0 1.5 1 21 219 239 219 240 0.87
4 17 3.3e-05 0.0042 18.5 0.3 1 23 251 274 251 274 0.95
5 17 0.0029 0.37 12.4 1.3 1 19 290 308 290 309 0.96
6 17 6.3e-06 0.00081 20.8 2.2 1 23 324 346 324 346 0.95
7 17 0.00047 0.061 14.9 0.1 1 23 352 374 352 374 0.97
8 17 0.00032 0.042 15.4 0.5 1 23 380 403 380 403 0.97
9 17 0.14 18 7.0 4.6 3 23 540 561 538 561 0.96
10 17 1e-05 0.0013 20.1 0.9 2 23 568 589 567 589 0.95
11 17 0.054 7 8.4 6.3 1 23 598 621 598 621 0.96
12 17 0.0053 0.68 11.6 3.0 1 23 627 649 627 649 0.96
13 17 1.4e-05 0.0019 19.6 1.0 1 23 654 677 654 677 0.96
14 17 0.091 12 7.7 2.3 1 23 683 705 683 705 0.97
15 17 0.0014 0.18 13.4 4.4 1 23 709 732 709 732 0.96
16 17 0.039 5 8.8 0.8 3 23 740 760 739 760 0.98
17 17 0.00011 0.014 16.9 1.3 1 23 766 789 766 789 0.95

Sequence Information

Coding Sequence
ATGCTACATCGCGAGGTCAAGCCAAGCAGCTCGGCAACCACCACGACAGTACGAGGCCGCGGCTGCGACGGAGAGGAGCCCACCGGTTCTGCACCTGTGACCAGATCTGCTAAAATTCGTTTCAGGGAATCACTGGATAAGAGTAACCCAACACCGGGGGACGAGCCACCAGCGAAGAAGCCAAATCCCCAGAGTAAGTGTATCCCGGATACCGCGAGTCCCGAAACCCAATCGGTCGCGAAGAAGTATTTCCTGCGCGGTGCGTCGAAGGACGCGGCGAAGGGAGAGCAGGGGGGCGCGGAGGTGCCCGACGACGTGGACGACCTCATGACGCTGCTGGCGATTTACAAGGAACTACCGGACGGCGGCTTCGTGTGTCAGCTTTGCGAGAATACGGATGGCATCAACGAGCTGCACGACAAGCCGCACGTGGTGCGCCACGTAATCCGAGCCCACGGCTTCAGCCATGCCCACGAGTGCCCCAGCTGCCCGAGCAGCTTCAAGCGGGAGTCGTGGCTGGCGAGCCACGTCGACGCCCTGCACAAGGCCGAGAAGCTCGAGCGGTACGTCGACTGCGCGAGGTGCTCGCACCGCAGCAAGGACGAGAAACTGCTCAGGCTCCACGTGCTCAGGAAGCACGTGGCCGTCTGCCGGTACGTCTGCGGCTGCTGCGGCAAGTGCTTCAGGACCCCGGCGGCCAAGAGCGAGCACGAGCGCCTCGCCGGGTACAGGAAGAAGCCCAAGGCCAAGTTCGAGTGCGACAAGTGCCAAATCGTAACCAAGACTAAAGACGACTTGGAGAGGCACATTAAAGACGTGCATTCGGGATGCCACTTCCGGATGATCTACAGGTCGTCGAAGCTGCAATACAAGTGCTTGATATGCAGCAAAGTATTCGTCTCGAAGAAGTCCTTCCACGAGCACGCGCCCTGCCAGGACAGCCCGGCCGAGGGCAATGAGGTGGAGGGCTTCCTGTGCAGCGAGTGCGGCAAGCGGCTTTCGAGCAAGGACCACCTGAAGAAGCACGCGCGCGTCCACAGCGGCGAGCGACCCTACCCCTGCCCCGAGTGCGGCCAGACCTTCGCCCTTCGCAATACTATGCGTATCCACGCCCTCTCGCACTGCGGTATTAAGCCTTACGTGTGCGAGATCTGCCGTTTCAATTACTCGCAGCGATCGGCCCTCATGATACACTGGAAGAGCAAGCACAAGGGcatgccgccgccgccgcccgtcGAGATCCACCAGTACTTCGACGCGAACGGCCAACTGCTCTCCATgaAATACAATTCTCGTTTGAGGAATAACAGTTCCAACTCCCGGATAAGAGTGCGCACAACCTCAGAACTTACCAATACTCCACAAGTCTTGGAAACGAGATCGACATCGCCCCGAGTTTTGACAAAAGCGGCAAAAGTCATGCCTAAGAAAACTAAGCGAGTCGCCTCCAAGAGGAAAAACACTATTTCAGCGGATGAATGTCAGCAGGAAGCGACCGCCGACACCTCCGCACCTCCcgataaaaaagcaaaagctgCCGATTCGCCAAAAGAAGAAAGTCAcgcaaaagaagaagaaaagccCGATTTTAAGAAGTTACGAGGCGGAGGTTTTGGTTGTACACTCTGCTTCCAGAAGTTCAGTCACCGATACAAGGTGAAGCAGCACCTGAAGTTGAAGCACAAGCCGCGCGAGGTAATCACTTGCGCCGACTGCGGCAAAAAATTCAAGACCAAGTACCAGTTCAACGTGCACGCGAATCAGCATCGCGAGAACAGTAGCGATTACCTTTACTGCTGCGACAAATGCGACTACCGTGCTAAATCTAAGCACTACCTCAAAACCCACGTGATTCGCAAGCACACCACCGAGTACAAATTCGAGTGCGCTCACTGCGACAAGCGCTTCAAAATGAAGATGGACCTGAAGTTCCACCTGGGCACCCACGGAACCTCGCAGCACATGTGCGACGCCTGCGGGCGCATGTATTCGAGCCAGGACTCGCTCCAGAAACACCGGCGTGTCGTCCACTTGAATGACTACAAATTCCAGTGCAACATCTGCCACCAAAAGTTACTCACGGAGGAAAACTACAAGAGTCACTTGGAGTCGCACAAAAACATGCACAGCTGCGACGAGTGCGACCTAAAGTTCACCAAGAAGTACTATGTGACGCGGCACAAGAAGCGCGTGCACAAGGTGGAAAAGACGAACCTGTGCCGCGTGTGCGGCAAGGCGTTCGTCTGCATGGCGACGCTCAGGGTACACTACCTGACCCACGTAAAGATTAAGCCTTATCTGTGCAACGTCTGCGGTTTCAGCTTCACCCAGCGATCTTCGATGATGCTCCACTGGAAGAGAAAGCACCCGGAAGCAGAGGAGCCACCTCCACCAGTAATACTTACCAATTTCTTCGAAGCCATAGAGACCGAAGTCGATAAAATCGCCGATAAGAACAACTCGACTGACAGTGGGTTGTGA
Protein Sequence
MLHREVKPSSSATTTTVRGRGCDGEEPTGSAPVTRSAKIRFRESLDKSNPTPGDEPPAKKPNPQSKCIPDTASPETQSVAKKYFLRGASKDAAKGEQGGAEVPDDVDDLMTLLAIYKELPDGGFVCQLCENTDGINELHDKPHVVRHVIRAHGFSHAHECPSCPSSFKRESWLASHVDALHKAEKLERYVDCARCSHRSKDEKLLRLHVLRKHVAVCRYVCGCCGKCFRTPAAKSEHERLAGYRKKPKAKFECDKCQIVTKTKDDLERHIKDVHSGCHFRMIYRSSKLQYKCLICSKVFVSKKSFHEHAPCQDSPAEGNEVEGFLCSECGKRLSSKDHLKKHARVHSGERPYPCPECGQTFALRNTMRIHALSHCGIKPYVCEICRFNYSQRSALMIHWKSKHKGMPPPPPVEIHQYFDANGQLLSMKYNSRLRNNSSNSRIRVRTTSELTNTPQVLETRSTSPRVLTKAAKVMPKKTKRVASKRKNTISADECQQEATADTSAPPDKKAKAADSPKEESHAKEEEKPDFKKLRGGGFGCTLCFQKFSHRYKVKQHLKLKHKPREVITCADCGKKFKTKYQFNVHANQHRENSSDYLYCCDKCDYRAKSKHYLKTHVIRKHTTEYKFECAHCDKRFKMKMDLKFHLGTHGTSQHMCDACGRMYSSQDSLQKHRRVVHLNDYKFQCNICHQKLLTEENYKSHLESHKNMHSCDECDLKFTKKYYVTRHKKRVHKVEKTNLCRVCGKAFVCMATLRVHYLTHVKIKPYLCNVCGFSFTQRSSMMLHWKRKHPEAEEPPPPVILTNFFEAIETEVDKIADKNNSTDSGL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01380799;
90% Identity
iTF_00713839;
80% Identity
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