Basic Information

Gene Symbol
-
Assembly
GCA_018907245.1
Location
JACCHV010000061.1:3225133-3230652[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 20 3.1 1.2e+03 2.1 6.1 2 23 253 275 252 275 0.96
2 20 0.046 17 7.9 3.6 1 23 348 370 348 370 0.97
3 20 0.00044 0.17 14.2 0.3 1 23 419 441 419 441 0.98
4 20 0.016 6 9.3 0.4 1 20 496 515 496 517 0.93
5 20 0.0037 1.4 11.3 1.9 2 23 558 579 557 579 0.96
6 20 0.0013 0.48 12.8 0.1 1 23 622 644 622 644 0.97
7 20 0.00031 0.12 14.7 0.1 1 23 650 672 650 672 0.97
8 20 0.00038 0.14 14.4 1.8 1 23 709 732 709 732 0.93
9 20 0.00024 0.091 15.0 0.3 2 23 740 762 739 762 0.96
10 20 0.00012 0.044 16.0 0.6 2 19 792 809 791 814 0.89
11 20 0.00014 0.053 15.8 1.3 1 23 846 868 846 868 0.93
12 20 0.09 34 7.0 0.0 2 20 926 944 925 944 0.95
13 20 0.00059 0.22 13.8 0.2 2 23 963 984 962 984 0.97
14 20 0.0011 0.43 12.9 3.6 1 23 1010 1032 1010 1032 0.97
15 20 0.017 6.4 9.2 2.4 3 21 1053 1071 1052 1075 0.88
16 20 0.66 2.5e+02 4.2 0.2 2 23 1132 1154 1131 1154 0.90
17 20 0.014 5.2 9.5 3.6 3 23 1184 1205 1182 1205 0.90
18 20 0.0019 0.7 12.2 0.9 1 23 1212 1236 1212 1236 0.93
19 20 0.061 23 7.5 2.0 1 23 1241 1264 1241 1264 0.94
20 20 0.007 2.6 10.4 0.3 3 23 1296 1317 1294 1317 0.95

Sequence Information

Coding Sequence
ATGGACGACGTTGTAGAGATTAGCGGCTTGGAAAATGCTTGCAGGTTGTGCCTTACAACCGAGCAATCTAGGTCGTCGATTTTCGGCGTGCCACACGTATCTGTTACTTTTGCCGACAAGATTCGTGCGTGCTTGTCAATACAGATTTCATCCAATGATAAAATATCAACTCTTGTATGTACATCATGTATCAAAAATATAAACCAATGGTATTCGTACAAAGATACGTGTCTAAGATCTCAAGAGAAACTTCAACAATGGTTAGCAAAACATTCTACATTTGTTCAACCGGTGGTGACTATAAAGGAAGAGCCACTTGATGTAGAATTTCCAGAGGATAATCTTCAAAACATAACCAATGAATCCAATATGACAAATCATGTTGGTTCAAATGGTGAAAGTATGGATATAGATACTGAATCTAATATTACAACTGGTAAAAATAATTTAGCTCAACCATCATTAGAACAAATTCCAAAAATAAATGAAAAAATTGATAAAGATCATGCATCAGCTATTCAAATTAAAGTTGAACCTGTGGACACAGAAGATGAAGATGATGCTAATGTAGATGTTGAATCTGTCAACAGTGGAGAACTTTTAATTAATCCAATGGCAGTAGTGGCTAGCAATGGCAATAATGATAGAATAATGGAGGCTGATTCAACTCAAAAATTTAGCGCAAGAAGGTTTGGAAAAAAAAGAATGCGTCGTGGTCCTCATACACATTACAGGGGTATTAGATTATTCAAAAAAAAGTGTGTTCATTGTAAAATTTATTTACATTCTAAATACTCATATACTCAGCATATGTCTAGATATCATGGAATAGTCAACAGTTTAACCAGTGATTTTGCAAAACCTTCAACTCAACCGTTAATAGCAAAACAAAAGTCAAAACTATCATTTCATACAGATAATATGGAATCTATTACAGATACACCAAATGATATTAACCAAGAAGACTCAGAATTCGAAAAAATGATAAAAACTGATCCTCTAATACCAGTTCAAAAGACAATTATTAGTCAGTTAAAGACATTTTCCTGTTATTCATGCAAGCAAACCTTCTTTGATCGAAGAAATACTTTAAATCATATTCGACAACATATGCCTGATTTACGACCATTTACTTGTATTGCCTGTCTCACTGAGTTTTCGGATAGATCTATGTATAAACTTCATTGTGGTGCTTCATTTGAGTGTGCCATGAAAATAGCTTTAGTAGTTCCCAAAGTAGGTAATGAAAAATATTTTACTTGCAACATGTGTCTTCGCCCTTTTGACAATCGTAAAGAACTTCTTACACATTTAGCTGTACATGCAGATAAACAATACCAACAGTTAGCTCAACCTTTACGAACTCCACCTAAGCTAAAGCCAATAGTATCACCTACACCAACTCCTAAGGTAGATTCTTCACCTCCTAAAAGATATCCTGCGAATGTATCAGGGCCTTACATGAATGGTGATCCAGCTCATAATCATATGTGTGATTTGTGTGGTATGATCTATAGGTACAAACCAAACATGTTCAAACATCGTGAACTTTGTTCTACTTTACCTGAAAATATCAGAACTTCCTACAGATGTATCCATTGTAACATGACGTATCTCGTGTATAAGAAATTTTATACACATGTATTAAACGATCACAAAAAACGTGAAATTGTCTGCTTCACGTGTCATGAGAAATTTGCAACTCCTGATGATTATCTCAGTCATCATGAAACGCATCGTATTCATGTAGATAAAGAAAATAAAAATGAAACTGCGAACGAATTGCAGACAAATAAAGAATACTCGATGATGGTAGATCCTTTAAATTCGTCTACACATCCTATGGATGTAAGCGAGAAGCCTTTTAATTGTGCCCTATGTGGCGAAGATTTCGCTACAAATGTCGAGCTTAGTGAACACCGTAATCTTCACTTGAAAGTAAAAATTTACTCGTGTGTTATTTGTCGCAGCATGTTTAGTAGTTCAGGAGCTCTTGAAGTACATATGAAAGATCATGGAATTGAAGATCCTGGTGAGCAGAATGCCAATACCTCTTGTGTTGAATACGGACGATCTCAGACTGCGATGAATGAATCATCCATTTCAGATCCTGGAGGATGTTTACACAATTGTCGTGCGTGTGGTAAAAACTTCTCGAATGTTGCGAACCTAAAAAGACATGAAAAAAATTTGCATTTCAAGCAGAGGCGTCGTTGGAGTTGTGACGATTGCAAGAGACGGTTTAAGTCGGTTGAAGCTTATAATGAACATGTAAGAACTGAACATGGACCAATGCAGGAACAGCAAAATATTGAGAAAGTATTGGCAATACCACAACCTCAACTGTCATCAAGTACTGGTAAACCATTAATGCAGTGTCCAAAGTGTCCCAAAACATTCGCTTATCAGGGTAATCTTATCATTCATTGTCAAAATGTTCATAAGGAGAACCATTACGAGCGTGCAAGAGCAAATTCAGCACGTCCTGTAGCTGCTCCTGCAACTCGACCTGCTTCTGCTGTTACGTCTTGGGGCCATTCCTGTGATGTCTGTGGTAAAACCTTTCGAGAGGAGCAATCGCTTAAAACCCATCGAGGTTGGCATCTTCGTTCTACTTATCGACTTAAGGTAGACAAGAACACTAGTTTAGATGAAACAACACTCAGTGGTCCAGGGTATACAATGACTATGACAAGTACAGCAAAGCCTGCAAAGGCGCGTAAATCTTTTCCTAATAACCCTCCTCAAAGACAGCTTAGTAATATCACCACCTTGCAGTGTCAAGTCTGCGATGATCGTTTCCCAGACGTTGCGGAACTGAGAAAACATCTCTGGGACGTTCATTGTGCTAGAAATAAACCCGAGAAGTCTTTCACAAGTGAGTTACAGTGTGAGCTTTGCACTAACAAATTCCCCGATGAAGAGTCTTTAGAGAACCACATGAAGTGGCATTCACAAAATCCAATTCTCAGTAATAATACCACCAGTGTTAACAGTCGAATTGGTCTTGATACACCTACTAAGACATTTTACTGTGATACTTGTGGAAAATACTATAGCAATCGCAAGCTTTACCTGCGGCACAAGAAACTTCACAAAGTCTTACCTCCTTCGACGATGATGAACCTTCAATCACTGCAAACAAAACGACCTTTCTGTCAAGCTTGTCAGAAGAGTTTTTCAACTGATGCATCTTTAAAACGGCATAAAGCATCTCCATGTCATCATAGTATGGCACGAACTCAGAACCAGCATGGACCTAAGAAGATAACGACAACGGCAATGATCCACCATCCGCCCTCGGAACCAGTGAGACTGCAGGCAGTCAAAAAAGAACCAGGTTACGAGTACACAAGTCATGGAGGTGGACATGGTACAAGGAAAAAGCCAGTTACATGTCTTATATGTAAGACCATGTTTCCGAATATGAGTATACTTTATCAGCATAAACAATTGGTGCATAAGTTGCCAACTAGCGGGAGAGATAGAGCCAACAGCCATCAGCAGGCTGAATGCGTGCCATTAATAAGTGCAGAGGGAATGGTTTGTTGCAATCTTTGCGGAAAACAGTTCCCAGGTGTTTCGAATCTCAAACAGCACTTCTCCCACAAGCATAAGGCAAAGAATACCACTTTCCCTTGCAGGTCGCCAGGTTGTAAACTTGTATTTAGCAGTGCCCATTCGCTAAAAAGTCATGAAACCACCCACACCAGTATGATTTACAACTGTCATCTATGTGATGGCCACGTATTTTCAAGAGCTGCTATGACTAAGCATATGATAACTATGCACAAAGCAATTTATCAATCAGGAGCAAGTAAAACTAATCTTTGGTCTGAGACGGATTTGACGACTTATAATGTCAAAAATTGCCAGAGTACAGCCTGTCCCAAGTGCAAAATTAAATATCCAAATTTGAGGGCATTGAAGATTCACTATATTAAATTCCATGAAAAAGCATAA
Protein Sequence
MDDVVEISGLENACRLCLTTEQSRSSIFGVPHVSVTFADKIRACLSIQISSNDKISTLVCTSCIKNINQWYSYKDTCLRSQEKLQQWLAKHSTFVQPVVTIKEEPLDVEFPEDNLQNITNESNMTNHVGSNGESMDIDTESNITTGKNNLAQPSLEQIPKINEKIDKDHASAIQIKVEPVDTEDEDDANVDVESVNSGELLINPMAVVASNGNNDRIMEADSTQKFSARRFGKKRMRRGPHTHYRGIRLFKKKCVHCKIYLHSKYSYTQHMSRYHGIVNSLTSDFAKPSTQPLIAKQKSKLSFHTDNMESITDTPNDINQEDSEFEKMIKTDPLIPVQKTIISQLKTFSCYSCKQTFFDRRNTLNHIRQHMPDLRPFTCIACLTEFSDRSMYKLHCGASFECAMKIALVVPKVGNEKYFTCNMCLRPFDNRKELLTHLAVHADKQYQQLAQPLRTPPKLKPIVSPTPTPKVDSSPPKRYPANVSGPYMNGDPAHNHMCDLCGMIYRYKPNMFKHRELCSTLPENIRTSYRCIHCNMTYLVYKKFYTHVLNDHKKREIVCFTCHEKFATPDDYLSHHETHRIHVDKENKNETANELQTNKEYSMMVDPLNSSTHPMDVSEKPFNCALCGEDFATNVELSEHRNLHLKVKIYSCVICRSMFSSSGALEVHMKDHGIEDPGEQNANTSCVEYGRSQTAMNESSISDPGGCLHNCRACGKNFSNVANLKRHEKNLHFKQRRRWSCDDCKRRFKSVEAYNEHVRTEHGPMQEQQNIEKVLAIPQPQLSSSTGKPLMQCPKCPKTFAYQGNLIIHCQNVHKENHYERARANSARPVAAPATRPASAVTSWGHSCDVCGKTFREEQSLKTHRGWHLRSTYRLKVDKNTSLDETTLSGPGYTMTMTSTAKPAKARKSFPNNPPQRQLSNITTLQCQVCDDRFPDVAELRKHLWDVHCARNKPEKSFTSELQCELCTNKFPDEESLENHMKWHSQNPILSNNTTSVNSRIGLDTPTKTFYCDTCGKYYSNRKLYLRHKKLHKVLPPSTMMNLQSLQTKRPFCQACQKSFSTDASLKRHKASPCHHSMARTQNQHGPKKITTTAMIHHPPSEPVRLQAVKKEPGYEYTSHGGGHGTRKKPVTCLICKTMFPNMSILYQHKQLVHKLPTSGRDRANSHQQAECVPLISAEGMVCCNLCGKQFPGVSNLKQHFSHKHKAKNTTFPCRSPGCKLVFSSAHSLKSHETTHTSMIYNCHLCDGHVFSRAAMTKHMITMHKAIYQSGASKTNLWSETDLTTYNVKNCQSTACPKCKIKYPNLRALKIHYIKFHEKA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00305786;
90% Identity
iTF_00708682;
80% Identity
-