Basic Information

Insect: Eupeodes luniger
Gene Symbol: zfh1
Assembly: GCA_951509635.1
Location: OX608073.1:270776144-270779862[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 8.9e-05 0.018 17.0 0.7 1 23 152 174 152 174 0.95

2 15 8.7e-05 0.017 17.0 0.9 1 23 180 202 180 202 0.98

3 15 0.00011 0.021 16.8 1.2 1 23 319 341 319 341 0.98

4 15 0.004 0.8 11.8 0.2 1 23 347 369 347 369 0.98

5 15 8.6e-05 0.017 17.1 4.2 1 23 397 419 397 419 0.97

6 15 0.0072 1.4 11.0 0.3 1 23 430 452 430 452 0.94

7 15 0.0046 0.92 11.6 0.6 1 23 458 481 458 481 0.95

8 15 0.24 48 6.2 0.4 5 19 492 506 489 507 0.91

9 15 0.00014 0.029 16.4 5.6 1 23 516 538 516 538 0.97

10 15 0.022 4.5 9.5 0.5 2 23 544 565 543 565 0.96

11 15 8.4e-06 0.0017 20.2 0.3 1 23 574 596 574 596 0.98

12 15 0.00096 0.19 13.8 0.1 3 23 604 624 602 624 0.97

13 15 5.1e-05 0.01 17.8 0.5 1 23 630 652 630 653 0.95

14 15 6.6 1.3e+03 1.7 0.3 1 23 663 685 663 685 0.91

15 15 0.037 7.3 8.8 0.0 1 20 1102 1121 1102 1124 0.93

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	8.9e-05	0.018	17.0	0.7	1	23	152	174	152	174	0.95
2	15	8.7e-05	0.017	17.0	0.9	1	23	180	202	180	202	0.98
3	15	0.00011	0.021	16.8	1.2	1	23	319	341	319	341	0.98
4	15	0.004	0.8	11.8	0.2	1	23	347	369	347	369	0.98
5	15	8.6e-05	0.017	17.1	4.2	1	23	397	419	397	419	0.97
6	15	0.0072	1.4	11.0	0.3	1	23	430	452	430	452	0.94
7	15	0.0046	0.92	11.6	0.6	1	23	458	481	458	481	0.95
8	15	0.24	48	6.2	0.4	5	19	492	506	489	507	0.91
9	15	0.00014	0.029	16.4	5.6	1	23	516	538	516	538	0.97
10	15	0.022	4.5	9.5	0.5	2	23	544	565	543	565	0.96
11	15	8.4e-06	0.0017	20.2	0.3	1	23	574	596	574	596	0.98
12	15	0.00096	0.19	13.8	0.1	3	23	604	624	602	624	0.97
13	15	5.1e-05	0.01	17.8	0.5	1	23	630	652	630	653	0.95
14	15	6.6	1.3e+03	1.7	0.3	1	23	663	685	663	685	0.91
15	15	0.037	7.3	8.8	0.0	1	20	1102	1121	1102	1124	0.93

Sequence Information

Coding Sequence: ATGGATACTCAGACATACGAGATCCCGTCATGGGTACCACAAATCGAACGTGGTCATGTAAGTGATCAAGGAATTATAATTGCCGATTCTGAAGGTGACAGTGGAAATCACACAGACTACTTGGTGCACGAGGTGCCATCAAACATTGACCAAATAGCTGCTGAAAATCTTATATTCATGGCACGTGATGGCCAAATGGAGATAATCGATGGCCAAAGTGAAGTTCATGGAGCGACAAATGATGATAGTGGTATTGTTAATTTTCATGATGACTATGCCGAAACTCAGATGGTCACCGAAGAGGTGATCACAGACGATTGGGTGCAGCATCAAGGAGAGGAAAGAGTTGAAATACCTGCTGAGCAGATATGTGGCTCTTTATCCCATGTTACAGCTCAAGACATTGAAGTGCCTTTGCCAACGGTTCAAGATGAATATACCGCCTTACGACCATATCCTTGTGATTTTTGCAGTCGTCGATTTCGTAAAAAAGCCAGTCTGATGAATCACATGGTAGCGCATCAGAATGACCGACCGTATGTGTGTAAATTGTGTGGATCGCGATTCTTCCGACGAAATGATTTGATAAATCATCTAAAAGTTCATGCTGAATCATCAGAGCTCGATGATAATGAATaTTTCGAAACAGATAGACAATCATCACCGCCAAATGATCATTACTACGATCAGGAGTGGCAGAAAGAAATAAAAGCGACCAAAAAACCTCGTGGGAAGCGAATTCCCAAAGGTCCTCCGAAAGAGGAGAACTACACAATCGATGAGACTCTTCGTCAGAGACAAGTAACACCACAAATCCATGAGGAAACCACAGCCAACAGacatcagcaacagcagcagcacgAACAGGAACAGTTCTATGAGGAGCCAGAAACCCCTGTGATagaagatatcaaaaacattcaaCATTTCCCTGTTATAGATGAAAATAAGCCATTTGTGTGTCAACAGTGTGGTTTGTGCTTTGCCAGGGAAAAGGCACTGTCATCACATGTGAAGAGCCATCGCAATGACTCAACCTTTGAGTGTGGAACTTGCAACGAAATGTTCTGGGATGCCAACACTCTTCAGGAGCATCAGAAGTCCCACCAATTCGAAGCTAGTAACTCCGAGTATGAGCCGGATGTGGATAACGAGAGTGATTCCGAGTCGGAATACAAATATGGGGATTTCTATTGCTCCCAGTGTGGCATGTCCTTCCATCGTCAGGATCTGCTGCGTCGTCACTCGAAGTCGCACATCAAGAAGGAAATCATTGATAAGGATCAGCATTGCTGCAATACATGCGGAGAGTCATTCGTCGAGGCATTGGATTTGCTGGCTCATGCAGAGATTCACGCAAGATATCCACCTTTCAAATGTGTTCTATGTGGAGAGTCGTTCTTTGAGGAGAGCACCATAAAACGTCATCTGACGAATCTGCATTCGGCTGAAATGACATCGAATTCGTGCATTCTCTGTGGCAAGGAGTGTCGGGATCGTAAGGCTCTCATGAAACATGCCTGGGACCATTCTCGGGAGAAATGCCATTCGTGTTCAAAATGTGGAAAGAACTTCCACAATAAAGCGCGCTTGAAGCGCCACATGGCATCTCACCGCGACAAGTCGGTGGTTTGTAATGTTTGTCAGGAGGAATTTCCCGATGGGCGTTCGCTGTCGAATCATAGGCATTCGCATAGCGTGAACGCATCGGGGAAACTGTTCCCTTGCAACGAGTGCGGTAAGACTTTTGGATCGAGGAGCTCGCAGCAGATTCATGTGCGTATTCATACGGGTGAGCGGCCGTACGGATGTCGTTATTGCTGGAAAGCATTTGCTGACGGTGGAACTCTTAGGAAGCATGAGAGGATTCATACAGGTGAAAAGCCATACGCGTGTTCGGTGTGTCCACGTGCCTTTAATCAGCGTGTTGTTCTCAGAGAGCACATACGCTCCCATCACTCCGGACTGGATTCCAAAAGGCAGACCTATTACTGCTCTGTGTGCTGCAGCGAGCTTCCATCATCAGGCGAACTGATTCAGCACCTTATTCAACATAGTGACATAAATACGGCGATGCAGCGGCAGCCTGTGACTGGACCAAGAAAATACAAACGCCGCCGAAAGCTCAAACCCCACGAAATTGACCGCCTGCGAACTGAGAACAAAAATAGCAGCGATATTGACATCTCAGACTTTGATATGGACAATGTCGATGATCTCCTCGGAATTCCCAATCAGACACCGCCGACAAACAAAAGCAATAGAGCTCCAACGCTATCCGAACAAACGTCTTCCACTTCTGGTGCTCTATTGGGATCGGCCGAGAGTGATTCGAAGAAACAGCGCTACAACTCGACTGGAAGTTCTGAGAAGTACACCAGCAACTGGCACACAAAGCTGATGAACACCTCGACAGAAGATACATACAAGTCACTGTTGTCGAACTTGGAGAATACATTGCAGAGTATCGATACTCTCGTTGTGAGTAACCCGTCATCGTATGGAAACAACACAGCACCTGCCGAGGCTCCTCCGCCGCCGCCAACATCAACACCAACGTCGTCGACAGCCGTAAGTCTTCCCAAAACTCCAAAGGCTTCCCGCAGCAGCAAAAAGATTGCCTCATCATCATCGAAGGCATCAAGTCGTCCGAAGATGATTCATACCGAGAAAACTCGTCTGCCCATAGAGAATGGGAAACGTAAAACGAAAACGTTCGTTACGCGCACCGAACCCACTGAACTGGACATGTTTAGCCAGCGGTCAAAATCCCATGCGAATGACTACGAAATCATCTCACCGGACAAATACCCGCCAAACCAGATTCAGTCTAGTCCGGTTCATATCAAACAGGAGATTGTCTGTAGTCGTAGTGAATTGTACGACGCTCAGCTTCTCCTAGAGGCCACATCGGCCCGCCGAGAATTGGACAAATACAATCCCGCCATAGTCAACGATCTGGAAGAGATTCTTCGATCACCTGACAAATCGAAATCCCCTCGCCGTCGGACGATCAGTGATCGGACAGATGATGAAATAAAAGCAGAGCCTCAATCACCCATTCACCAGAATTTCGATTTTGTTCGCAGATCCACTCGGCCCAGGCGGCCAGTGGTGAATAGAAAGTATCTGGCTTATGAAACCGATTTGCCTTCACCTGCAGCTAAAGCCAAGCCACGTGTTGAGAAACGTGAAAGTAAAGCCTTCGTAAGTTCACCTGCTCGCACTTCTGTGAAATCTTCGTCACCGATACCATCCCCGCCACCGACGCCTCCTCCACCACCAGTCAGGAAGCAGCACTATTTTGAATGCGAGATGTGTTCGTCAGTATTTCCAGATCGTGCACAACTTTTAGACCATGTACctattcatatttaa
Protein Sequence: MDTQTYEIPSWVPQIERGHVSDQGIIIADSEGDSGNHTDYLVHEVPSNIDQIAAENLIFMARDGQMEIIDGQSEVHGATNDDSGIVNFHDDYAETQMVTEEVITDDWVQHQGEERVEIPAEQICGSLSHVTAQDIEVPLPTVQDEYTALRPYPCDFCSRRFRKKASLMNHMVAHQNDRPYVCKLCGSRFFRRNDLINHLKVHAESSELDDNEYFETDRQSSPPNDHYYDQEWQKEIKATKKPRGKRIPKGPPKEENYTIDETLRQRQVTPQIHEETTANRHQQQQQHEQEQFYEEPETPVIEDIKNIQHFPVIDENKPFVCQQCGLCFAREKALSSHVKSHRNDSTFECGTCNEMFWDANTLQEHQKSHQFEASNSEYEPDVDNESDSESEYKYGDFYCSQCGMSFHRQDLLRRHSKSHIKKEIIDKDQHCCNTCGESFVEALDLLAHAEIHARYPPFKCVLCGESFFEESTIKRHLTNLHSAEMTSNSCILCGKECRDRKALMKHAWDHSREKCHSCSKCGKNFHNKARLKRHMASHRDKSVVCNVCQEEFPDGRSLSNHRHSHSVNASGKLFPCNECGKTFGSRSSQQIHVRIHTGERPYGCRYCWKAFADGGTLRKHERIHTGEKPYACSVCPRAFNQRVVLREHIRSHHSGLDSKRQTYYCSVCCSELPSSGELIQHLIQHSDINTAMQRQPVTGPRKYKRRRKLKPHEIDRLRTENKNSSDIDISDFDMDNVDDLLGIPNQTPPTNKSNRAPTLSEQTSSTSGALLGSAESDSKKQRYNSTGSSEKYTSNWHTKLMNTSTEDTYKSLLSNLENTLQSIDTLVVSNPSSYGNNTAPAEAPPPPPTSTPTSSTAVSLPKTPKASRSSKKIASSSSKASSRPKMIHTEKTRLPIENGKRKTKTFVTRTEPTELDMFSQRSKSHANDYEIISPDKYPPNQIQSSPVHIKQEIVCSRSELYDAQLLLEATSARRELDKYNPAIVNDLEEILRSPDKSKSPRRRTISDRTDDEIKAEPQSPIHQNFDFVRRSTRPRRPVVNRKYLAYETDLPSPAAKAKPRVEKRESKAFVSSPARTSVKSSSPIPSPPPTPPPPPVRKQHYFECEMCSSVFPDRAQLLDHVPIHI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00389816;
90% Identity: iTF_00894189;
80% Identity: -