Epri002622.4


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Euceroptres primus
Gene Symbol
Rfx2
Assembly
GCA_037177015.1
Location
JBAGKK010000333.1:19986-32137[-]

Transcription Factor Domain

TF Family
RFX
Domain
RFX domain
PFAM
PF02257
TF Group
Basic Domians group
Description
RFX is a regulatory factor which binds to the X box of MHC class II genes and is essential for their expression. The DNA-binding domain of RFX is the central domain of the protein and binds ssDNA as either a monomer or homodimer [1]. It recognize X-boxes (DNA of the sequence 5'-GTNRCC(0-3N)RGYAAC-3', where N is any nucleotide, R is a purine and Y is a pyrimidine) using a highly conserved 76-residue DNA-binding domain (DBD) [2].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 3.4e-37 6e-33 115.5 0.0 2 78 364 440 363 441 0.97

Sequence Information

Coding Sequence
ATGAAAGGAGAAGGCGTTATTGATATTGATACAGCCAATACTAAAGGTGTCTATACTTGTGTTGCAGAACCATCCCTTCAGATTCGAGGAGGCGGAGGTGGTAGTGATACGCCAGGAACTGAGAGAGGTGAGGGAGTGATTGCCATGACTACGACAGGAGCCCAGTATGCTCTCACAGCATCCGCTGGGGCAGGCAATGGCGGGGGTGCCTCCACGGCAGTGGGGGTGGATACCAAACCAAGCGTTGTCGCTTTGACTACAACTTCCAGTGTCAATAGTACTACGTGCCAGGCTCAATCCACCAGAGGTCAACAAGTTATCACCGTTGTTACCAGTCCTGACCCATCAAGCCCCAATAATCTCCAACCGATTCAGTTGCTGGTACAGGATTCGCTAGACACAGCCGCAGATTCTTCAAACGGTTCTTCAGGTACACCAGCACATGTAACAGCGCAGGTAGTAGTGAATACCGCTCATACTGGTCAACATACTCTTGTAGATTCGGACGTGACTTCCACATCGGCTGGGACCATCGTCAGTGGCTCACCGCACTACATCACAGTTAccgGCACCAGTGATTCGCCATCATACGCATCCCTCACAACGGCAGTAGTGGCTGGCGACGCCGAGGCAGTGGGGTCCGATTCAGTTTCACATCCAACGTATGTTCAATATGTCGAGGGAGATGGATCCGCGTATATTCCGACGAATGGCCAGATgaCGTATCCTGTTTATGCTGTCGGCGAGGCAGGAACTATGTACACACCATCCTCCAGTCAATATTTCACATCAGCCACAACACCAGTAACTTACGCAcagGTTCAGGGTTCAAATACAACAACCGGGCAATTATTATCTCAAGGAAATGGAGCTTATCTCATACAGCAAAGCGTCGTGGACGGAGATGCAGCAACTCACGCGCTTATTTCTGCCGCAGCGGCTCGTGCCAGCCCTCAAACCGAAAGTGCGGAGGCGGTGGTTAGCGGTGGTGGAGGGGCATACTTGATCAGCGGTAATTCAGGTAGCACTACTGTCAGCGTGGAAGAAGCTGCTGCTGCTGCGAATATGACGCATGCCACTAGAGTCTCCCAGGCCACCGTGCAGTGGCTCCTAGAAAATTATGAGACTTCAGACGGAGTCTCCCTTCCAAGATCAACACTTTACAATCACTATCTTCGCCATTGCTCGGATAATAAACTGGATCCCGTAAACGCAGCGAGTTTCGGGAAATTAATTCGCTCGGTGTTCCTGGGACTGAGAACAAGACGCTTAGGCACTCGAGGAAACTCGAAATACCATTACTATGGAATTCGTGTCAAGCCCAACTCGCCACTGATGCTGCTTAATGAAGATGGAACTTCTCGCCAACAAACTACGCCAAATTCGCAGGCAAAGCGATTTAAATTTGTGAATCAAAAACAGGAAACCTCGTACGACACCAATGCTCACTCCAATGCTAACATTTCTTCTAATAACTCCCCGCCTCAGTATCAGCAATATCTAGGCGAAGCGGGTAGCGCCATTCCTGAGTTTCCGGAAATTATAGTTGGACACGGATCATCTCTGCCGGAAGATTGCACCTTGGAAGACATTGACACATTCCGCAGTATCTACAGAGAACACTGCGAAGCTTTCCTAGACGCTGTGTTGAATTTCGAATTTGCCACAGTTGAAAGTTTATGGAGGGAATTTTGGCGTAGTCAGGATAATAACAATGGTGACGAGTGTGAggaggaaaaatatttgtccAAgaCGAAACTCTATCAAATGTGCAAGTGCTCCGAGGTTCAAGATTTCATCAGACGGGTTGATTACACCTTTTATCAAAATCTAGTCGAAGTTCTGATGCCCGATGTTCTGCGACCCATTCCTAGTTCATTGACTCAGTCCATAAGAAACTTTGCCAAGGGTCTTGAATCGTGGTTGACATCAGCCATGAATGATTGTCCAGAAGAAATGATGCAAATAAAGTTAACTGCAGTTTCTGCTTTTGCACAAACGTTGAGGCGATACACTTCCCTGAATCATTTGGCTCAAGCTGCGCGAGCTGTACTTCAAAACTCTAGTCAAATTAATCAAATGTTAGCAGATTTGAATCGAGTAGATTTCCACAATGTCCAGGAACagGCATCATGGGTATGTCAGTGCGATTATGCAGTTGTGCAGCGTTTGGAAACTGACTTCAAAGTTACACTGCAACAGCAGAATTCACTGGAGCAATGGGCAGTTTGGTTGAAAGGAGTTGTAACTCAAGTTCTTAAACCTTATGAGGGCAAACCAACTTTTGCTAAAGCTGCACGACAGTTCCTGCTGAAGTGGTCATTTTACAGTTCAATGGTTATACGAGATCTCACATTGAGAAGTGCTGCAAGTTTCGGATCGTTTCATCTCATCCGCTTACTTTACGATGAGTACATGTTTTACTTAATCGAACATCAAGTTGCTGTCGCTACAGGCACGACTCCCATAGCTGTGATGGGTGACAAAAGCCAAAACTCTCCTGTGTTCTACGCTTTCGGATCAGCTTCAAACGgagATGCATCGGGTATGAATCAATCGAAACGCATGAAGATGAGCTAA
Protein Sequence
MKGEGVIDIDTANTKGVYTCVAEPSLQIRGGGGGSDTPGTERGEGVIAMTTTGAQYALTASAGAGNGGGASTAVGVDTKPSVVALTTTSSVNSTTCQAQSTRGQQVITVVTSPDPSSPNNLQPIQLLVQDSLDTAADSSNGSSGTPAHVTAQVVVNTAHTGQHTLVDSDVTSTSAGTIVSGSPHYITVTGTSDSPSYASLTTAVVAGDAEAVGSDSVSHPTYVQYVEGDGSAYIPTNGQMTYPVYAVGEAGTMYTPSSSQYFTSATTPVTYAQVQGSNTTTGQLLSQGNGAYLIQQSVVDGDAATHALISAAAARASPQTESAEAVVSGGGGAYLISGNSGSTTVSVEEAAAAANMTHATRVSQATVQWLLENYETSDGVSLPRSTLYNHYLRHCSDNKLDPVNAASFGKLIRSVFLGLRTRRLGTRGNSKYHYYGIRVKPNSPLMLLNEDGTSRQQTTPNSQAKRFKFVNQKQETSYDTNAHSNANISSNNSPPQYQQYLGEAGSAIPEFPEIIVGHGSSLPEDCTLEDIDTFRSIYREHCEAFLDAVLNFEFATVESLWREFWRSQDNNNGDECEEEKYLSKTKLYQMCKCSEVQDFIRRVDYTFYQNLVEVLMPDVLRPIPSSLTQSIRNFAKGLESWLTSAMNDCPEEMMQIKLTAVSAFAQTLRRYTSLNHLAQAARAVLQNSSQINQMLADLNRVDFHNVQEQASWVCQCDYAVVQRLETDFKVTLQQQNSLEQWAVWLKGVVTQVLKPYEGKPTFAKAARQFLLKWSFYSSMVIRDLTLRSAASFGSFHLIRLLYDEYMFYLIEHQVAVATGTTPIAVMGDKSQNSPVFYAFGSASNGDASGMNQSKRMKMS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00254817;
90% Identity
iTF_01394019; iTF_01389928; iTF_01389162; iTF_01391690; iTF_00880972; iTF_01393231; iTF_00979830; iTF_01392502; iTF_00064192; iTF_01390817; iTF_00460227; iTF_00882693; iTF_00200490; iTF_00881739; iTF_00879359;
80% Identity
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