Esep001025.1
Basic Information
- Insect
- Eristalinus sepulchralis
- Gene Symbol
- Lztr1
- Assembly
- GCA_944738805.1
- Location
- CALYJE010000007.1:4085224-4088142[-]
Transcription Factor Domain
- TF Family
- BTB
- Domain
- zf-C2H2|ZBTB
- PFAM
- PF00651
- TF Group
- Zinc-Coordinating Group
- Description
- The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 4 1.9e-13 6.4e-11 42.5 0.0 1 107 417 548 417 551 0.85 2 4 0.065 21 5.4 0.2 78 108 551 581 547 583 0.89 3 4 1.2e-19 4.1e-17 62.4 0.0 8 97 642 731 637 745 0.88 4 4 0.82 2.7e+02 1.9 0.1 67 99 734 767 730 775 0.85
Sequence Information
- Coding Sequence
- ATGTTGAAAGCGATACTAGGCAGTGAGTCCGATCCCACtgaggacagtggtggcggagctggctgtaataacagtattggcggtagtggtggaagtggtggcggtggtatcgctggtggtggggtgagcgctagctgcAGTGGATGCTCATTCACTGGCAGTTGTGAGAAGTCTGGTAGTCGAAAGGGTCGACAGAAGTCCGTATCACCGGGTAGTTTTAGTTGCAATGCACTCAGCGTGGACTTCTCTTCATACACTGCTACGCATCAGTGGACTAAAATGCTGGATTGTGCCGAATTTGTTGGAGCAAAACGAAGTAAGCACACCGTGGTGGCGTACAAGGATGCCATGTTTGTTTTTGGTGGTGACAATGGCAAGACTATGCTGAATGACTTGATACGATTCGGTGTAAAAGACAAATCTTGGGGAAGAGCCTGCGTAACAGGCACCGCCCCTGCACCCAGATATCATCACTCAGCAGTGGTCTATGGTAGCTCGATGTTCATTTTCGGTGGATACACTGGAGATATTCACTCGAACTCGAACTTGACAAACAAGAACGATTTGTTCGAGTACAAGTTTCAGTCTGCTATGTGGGTGGAGTGGAAATTCTCTGGCAGAATGCCTGTGCCACGTTCAGCCCACGGGGCAGCTGTATACGACCACAAGATGTGGATATACGCTGGCTACGATGGCAATGCGAGGCTAAATGACATGTGGACACTGAACTTGACTGGCGAAAACCATCAATGGGAGGAAATAGAACAGAATGGTGATAGGCCACCAACTTGCTGCAACTTCCCGGTTGCAGTAGCAAGGGATTGTATGTACGTTTTCTCGGGACAGAGCGGCTTGCAGATCACCAATTCGCTGTTTGAGTTTCATTTTAAAACGAAAACCTGGCGACGAATATCCAACGAACACGTGCTACGTGGCGCATCATCACCACCGTCCCGTCGTTATGGGCATACCATGGTTCACCACGATCGATTCCTCTACGTCTTTGGCGGTTCGGCCGACTCGACCCTACCCAACGACCTCCACTGCTACGATTTGGACTCGCAAGTTTGGTCTATCGTAGCACCCGAACAAAATTCCGACGTACCCTCAGGCCGCGTATTTCACGCTTCTGCTGTTATCGGTGATGCGATGTACATATTTGGCGGAACAGTTGACAACAGTGTCCGACGTGGTGATACATACCGATTTCAGTTCTCCAGCTACCCCAAGTGTACCCTGCGCGATGATTTTGGAAAATTTTTTAACGAGAAGCAATTCTGTGACATTCAGTTTATCGTCGGTCCCGAGGCGATAAAAATTCAGGCACACATCGCATTCGTTGCGGCGCGATCGAAATTTTTGCGAACGAAGATACTGGCCGCTCGCGGGGCCAGTAACGCGAATTTACAGAAGCTTATAGGAACGGCTGACGTACCGTTTAACGATAGACCCTTGCTGGAAGTACGGCTCTTGAACGCACCGCCGGAGGCGTTCGAAATCATTTTGAACTACATCTACACGGATCGCATTGATCTCAAGGACTCGTACAGCAAGAACATTGTCATTCTAATAACGGACATCTACCAGCTGGCTGGACAGTTTCTCATGCCGAGACTGGCCCAGGGCTGCATCCAGTATCTGGACTTTAAGACATCGAAACAAAATGTGTTGGAGGCACTGTACAACGCTGACAAGCACAAGATACAAATCATTAAGGATCACTGCATGCAATTCATCGTTAAAGACGAGAACTTCACCGATGTGGTGATGTCTAGTGAATTCAGCGATTTAGACAAACCCCTCCTCGTAGAGATCATTCGGAGACGTCTGAATCCGAGCAAATCCAATCCGGACGCTAACCTCGAAAAGAATGTCGGCACTACACTGGAAAGTGACATGGCCGTCTTTCTCGAGTCCTGCGGGAAGGATTTTTGTGATATAAACCTTGTCCTAGACGGGCAGGTGATTCCGGCGCATAAATCGATTCTTTCTGCTCGCTGCTCCTACTTCCAAGGTATGTTTCGCTCCTTCATGCCACCAGACAACACAGTCAATATACAAATTGGCGATGTCTCACCTTCCTTGGAATCATTCAATTCCCTGCTTCGTTATATCTACTACGGAGAAACTAAATTGCCCCCGCAAGACGCTCTCTACTTATTTCAGGCCCCCTGCTTCTACGGTCTCTCCAACAGTCGATTGCTTGCATTCTGCAAGTACTCCGTGCAGCACAACATCACCTACGAGAACGTGTTGCAGACCCTAGAAGCAGCCGATTACACCAAAATAGTCGACATCAAGGAATACGCGCTGCGGTTGATAGTCAGGGAGTTTGGCACAGTTGCCCGGCTGCCAAAGATGACCGGACTCAGTCGGGATCTGCTGCTTGAGATTATCCGCGCCGTAGCTGATGGCCGTTCGGAGCCTCCGACCCAAATTAGTATCAATACCGATCTTTGA
- Protein Sequence
- MLKAILGSESDPTEDSGGGAGCNNSIGGSGGSGGGGIAGGGVSASCSGCSFTGSCEKSGSRKGRQKSVSPGSFSCNALSVDFSSYTATHQWTKMLDCAEFVGAKRSKHTVVAYKDAMFVFGGDNGKTMLNDLIRFGVKDKSWGRACVTGTAPAPRYHHSAVVYGSSMFIFGGYTGDIHSNSNLTNKNDLFEYKFQSAMWVEWKFSGRMPVPRSAHGAAVYDHKMWIYAGYDGNARLNDMWTLNLTGENHQWEEIEQNGDRPPTCCNFPVAVARDCMYVFSGQSGLQITNSLFEFHFKTKTWRRISNEHVLRGASSPPSRRYGHTMVHHDRFLYVFGGSADSTLPNDLHCYDLDSQVWSIVAPEQNSDVPSGRVFHASAVIGDAMYIFGGTVDNSVRRGDTYRFQFSSYPKCTLRDDFGKFFNEKQFCDIQFIVGPEAIKIQAHIAFVAARSKFLRTKILAARGASNANLQKLIGTADVPFNDRPLLEVRLLNAPPEAFEIILNYIYTDRIDLKDSYSKNIVILITDIYQLAGQFLMPRLAQGCIQYLDFKTSKQNVLEALYNADKHKIQIIKDHCMQFIVKDENFTDVVMSSEFSDLDKPLLVEIIRRRLNPSKSNPDANLEKNVGTTLESDMAVFLESCGKDFCDINLVLDGQVIPAHKSILSARCSYFQGMFRSFMPPDNTVNIQIGDVSPSLESFNSLLRYIYYGETKLPPQDALYLFQAPCFYGLSNSRLLAFCKYSVQHNITYENVLQTLEAADYTKIVDIKEYALRLIVREFGTVARLPKMTGLSRDLLLEIIRAVADGRSEPPTQISINTDL
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01055302;
- 90% Identity
- iTF_01356997;
- 80% Identity
- -