Basic Information

Gene Symbol
Aef1
Assembly
GCA_955652365.1
Location
OY019134.1:73555853-73556491[-]

Transcription Factor Domain

TF Family
zf-GAGA
Domain
zf-GAGA domain
PFAM
PF09237
TF Group
Zinc-Coordinating Group
Description
Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 4 0.00071 6.9 7.6 0.5 19 48 82 111 68 115 0.78
2 4 1.1e-05 0.1 13.4 0.0 21 52 112 143 110 145 0.89
3 4 0.0024 23 5.9 0.0 21 51 140 170 138 171 0.87
4 4 9.6e-05 0.93 10.3 0.1 21 47 168 194 166 199 0.89

Sequence Information

Coding Sequence
ATGACTAATTGTGAAATCGTTATCGTTGCTACCGATGAACAAGCAACCGATATACAAATCCCATTCAACGTGATAACCTCAGCGGCAACAGTTTCAGCGACTGGTGCCACCACTACGACTCATCACCTCGCACCACTGCAACAGCATActgagcaacagcagcagcagttgctACAGGGTGATACTCTGCAGCAACAAGTGCAAGCCGGCACCCTACCGCCGCATCTAGATCGTCCGCCCACAGCAGGTCCTGAGAAACCATTCCAATGCAACATATGCGAACGGCGATTTCGGCAACTGAGCACCCTAACAAATCacgttaaaattcacactggCGAGAAGCCCTACAAATGCACGATCTGTGACAAAACCTTTCGACAATCGAGCACCCTCACAAATCACATGAAAATTCACACTGGCGAGAAACCGTTCATCTGCTCATTCTGTCCCAAGCAGTTCCGTCAGCTGAGCACACTCACGAATCACCTGAAAATCCATACCGGAGAGAAACCATTCGAATGTGCCGTCTGCAAGAAACAATTCCGCCAATCGAGTACGCTCAACAATCACATAAAGATCCACGTCATGGACAAGGTGTATATACCCGTGAAGATCAAAACGGAGGAGGACGAGGGATGA
Protein Sequence
MTNCEIVIVATDEQATDIQIPFNVITSAATVSATGATTTTHHLAPLQQHTEQQQQQLLQGDTLQQQVQAGTLPPHLDRPPTAGPEKPFQCNICERRFRQLSTLTNHVKIHTGEKPYKCTICDKTFRQSSTLTNHMKIHTGEKPFICSFCPKQFRQLSTLTNHLKIHTGEKPFECAVCKKQFRQSSTLNNHIKIHVMDKVYIPVKIKTEEDEG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01223723;
90% Identity
iTF_00672533;
80% Identity
iTF_00671151;