Basic Information

Gene Symbol
-
Assembly
GCA_951394125.1
Location
OX596028.1:19289810-19295092[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.081 7.5 7.7 4.2 1 23 1192 1215 1192 1215 0.97
2 12 0.00028 0.026 15.5 5.3 2 23 1379 1400 1379 1400 0.97
3 12 2.7e-05 0.0025 18.7 0.3 1 23 1406 1428 1406 1428 0.97
4 12 1.7e-07 1.6e-05 25.6 3.6 2 23 1435 1456 1434 1456 0.97
5 12 8.1 7.6e+02 1.4 0.1 6 23 1470 1487 1468 1487 0.95
6 12 0.0088 0.82 10.8 3.4 3 23 1494 1515 1492 1515 0.95
7 12 0.16 15 6.8 0.1 2 23 1526 1546 1525 1546 0.96
8 12 0.00022 0.02 15.8 0.8 1 19 1552 1570 1552 1571 0.96
9 12 0.00014 0.013 16.4 0.4 1 23 1582 1604 1582 1604 0.98
10 12 0.00025 0.023 15.7 9.0 1 23 1610 1632 1610 1633 0.96
11 12 0.0013 0.12 13.4 4.7 1 23 1638 1660 1638 1660 0.98
12 12 0.0016 0.15 13.1 6.0 1 23 1666 1688 1666 1689 0.96

Sequence Information

Coding Sequence
ATGGGTGGAAACGTGCAATGTCCCGTTTGTACACTTTTCTTGCTTCCGGGCATGAATTTGTCGGATCATCTGGAAACCCATCCAAAAGAACAGGTCATAAAAGCCCTGGTTCAAATGAGCCTTAAAACTGAGACAACTGAATCGATAACTCCAGATACTCCTAAAAAAGCCAACAAATTTTCTTTCGCAGAGGCTGCCGATGAAACTTCTCATCCAGCCACAGAAGATGAAAGACATTCTCCAATATCGGAAATCAGTGACAGTGCAAGTAACAGTGCACCTGGTTTTGTGGAACCGGCAGCTACAAAACGAACTGAAAAAGAGAGCAATAATACGTTGCTCCCAGCTGCGCCGCCTCCAAATGTATTGAACAGACAAGGTGTTTATATGTTTGAAaataacagcagcagcagcaacagtagTAGCAGTACTTTCTTTGGACCACTGACCCCATActatcatcaacaacaacaacaacaacaacaacagcagcaacaacaacaacagcagcagcaacaacaacaacaacaacaacaaaataatcatcatcatcatcatcatcaacatcaacaattgcaacaacaacaccaaccgcATGAAGATCTAAATCATCAACAGCATCAGCAACATGTTAATCATAACTATCAACCTTACCATAATCTCTCACAGGGTGGAAACATTAATTTCACTGGCCACGGACCAACACATCCTCCGATGCGActTTTCTCCTATCAACCAACACCCAAGCCATTGCAACCACCACCTGCATATGGCGCTGCCATAAGTCAACTTCGATCTCAAAATAGCCAAAACCTAATGTCAAACACAACTCATCGGCCGTTGTATTCTCCAGGAAACTACACTCTTCCACCATCGGGGTCAATATCAGCGTCTACATCATCGACACCATCTCGTCTGCCTCCCCCACTTCCGCCACCACCTCTTAATCAACGCTATCAGTCGAACTTCGAGACAATGGAAACAGCCTTTACTGACGCAGTTGATACGAGTGCAATATCTCCAAGGCGAACTTCGATGACACCACCAATCAGACCTCCTCCCCAATTATATCGTTCACCTCAATCTTCATCAAATGCCCAATTCAGTAGACAGTCAAGCTCCCCCTACCCAGTTATGTCAGGCTCTCCATCCGTATTGCGGTTTGCTGAATCGCCTGTTACAGCACACTACCTAGAGCGAGAGAATGGTGATTTCATTGTACAAGAAACACCTAAGCATGTCGTAGAGTGCGTAGAAAAAGACGATGGAGAATTTTCTGTGATCGAGCGAGTCTATCATATGCCACCGAGTGTTGTTCAAATAAATgaagacgaagaagaagaattgtCCGAACACGGATCAAATAGTGAAGATGTCAAACTGATTGAGGACGATCATCCCAATGAAAATTGGACAATTGGCGAATCCTCCGATCAAGGACAAACATTAGAGAAACCAGAAAAAACGCCAAAAAAATCTGGTATAACTGTACTCAGTGATGTACAATTAGATTTAAGTGAATATCTAGACCTAATGGGTAACATAATAGCTTCTGGAAAGGTTGCTAAAAATCGATCTGAATtgataaaagttgaaaaattcgaaCCGGAAGAAGTGAAACAAGAAGAAACAATATGTCTGGATGACAATGATAATTCTGTTGCTTCAATGAACACTAATCAGAAATGTGACGagacagaagaagaaaaactagAACTTAGTAATGAGTCATCAGTTTATTGCCCTTTACCGCTGCCACCGGCTTTTTCAAAGACAGAATCGTGTGCAACATCATCATTAGTGGTTCCGGTGACAACAAGTGTTATTCGACTGGCGGCAACAGTTAATGCAAAACCCAGTACACTTGTAACTGCTGCAACAAATACTGAGGAGCCTATTCATAAAGAATCCTCTAACACACTAACAACGGGAAAGGTAGAGGAGCAAATGGAAATAAGTGATGTTGAGGAAGAGAAACCTACAACTAGccttaaaatagaaatagaatcaACAAGCAATAGTAAACCATCTTATATGGATGTGAATTTAGTTGAAACCAGCACACCTACAAACAAGACTGAGGAAGcattaaaaacaacaagtttAGAAGAAGCTCCAATTGAAGATATTTCTACACAACCAACAAATGAATTACCAGACAAAACTGAAAGCAGAAACGTTAATTTACCAATTAATTCGTTCCATCAAACATTGAAGCGGCCAATAAAGAAGGGTCCCAAAAAGCTTATAATTAAGCCAAAAAGCAAAGATGCTAGTACATCTCAAGCAATTACAGAAAAGACGGCAACTTCAATCAGTGATCCCACGCCGTCAATTCAAATGCCAATGCCAATATCATCTACCTCGACTGAAACTTCAAATCTAatacagcaacagcaacagcaaaagGAAGAAGTAACTCCAAAAGATTCCTCACCTCGAGATGAACTGAATAGTATTAAGATAGAAAGTTTATCTTCTGTTACATCGGATCCAATTCTCTTGAGGCCTTTGCTTGCTGACGCTGATGAGAAACTTCCGCCTGAAGATGATGCGCAACTTCAACCCCAACCCCAACCCTCAACATCAAATTCAATAGTTTCAGAAGAGAAACGAGGCACGGAAGAGTTTCATTTGGAAGGGCAAAAACCCACCGCTGATTTAACAGCCTTCATTGATGAGTGTCTAAAAAAagaggaagaagaagaacaTCCTATGCATTCAATTTTTGGAATGGATATCAGAGCTACTGAAGAAACTTTAAGCAATGCATTGACTCCACCGCCGCCGACTCCTGAATTTCCATCCCCTTCTTTGTTTGCAAAGCCATTGACAACGACGACGTCTGAAAATCTGTCGATTCCAGAATCAATGCTTCTCGATGGCAGTAATTTACATGAACCAGATGATCACCAACTACACCACGACCAGCAGCAGGAACATCAGCAAAGTAATTCCAACTTTGTGGAGTATCCGTTTAGTTTCCTTTATGGTGGCGAAGCAAATCACGAAGAAGAGGACGACAAACACAATATCCCAGCACCAATTTACTGTACTGAGGATTTCAACAAATACAGCGTTAGTACAAGTGGAGGTAACAGTGCTAGTTGCACTTGGTATCAGTCACAAAGCAGTGAAAATGATTTCGAGATGGATGGAAAAGGAAGCTACCTTGATTTGGATTCTTGCAAGCGAAGTACCTCGTTTGCAGCCGCCACGGAGGGCAGTATGCCAACTTCGGATGCACTTAATATAAGGACAGATGAAAAGATGCCTGCAAAGGGTGAGATCTCAGAACAAGAGAGTAATTGTGGTGTGGAGAATTCATGGAGCCAACcgCTTTACAATGAGTTTGCTGTTCGTTTCCCGAACCCTTATCAAAATTTCATGTCAAATCACGAGAGTTGGAGCCAAGATCATTACTTTCGTCCCCAGGATTTGAGTTCGTctgttgaaacaaaaaatttcccTTTGCATTCAACGGAAGAACCATCGGCAGTTATTGATGCACTTCCATCTACATCAAAGCGAAAGAACAAAGAAACGATAGCAAAATTGCCGCGAAAGAAGAACTTCCAGTGTACCCACTGCAACACTCACTTTCCACTGCTTAAAGAGAAGAACGCACATATGATAAAGCAACACGGTTATAAGCGTGTTAACCGCCGACTGATTCGTGACCCACCGACGTCAACTGTTACTACAGCAACTCTAAATGCAGTTGACCCCGCTGGAGCTGCGTCTTTGTTACTGGGCCTGGATGGAAATGCACGACCATCTTTGCCAGTTGGTGAAGATGAAGACTCTAAAGCAGCGATTGTTAAAATTGAACAAGAAAATCAagattgtaaaaacaaaaatgtttccaacTTGGCAATAAGTAGCAAAAAAGTAACTTCTTCCACATCAGCGGCAAATAGTGCAACAAATGTATCACGCACTAAGTATGACTCGATGCGGGCTCGAGATAATCGAATGCTTATAAACTTCAATTTGAGTGcgctaaatgtaaaaaatgaagGCGAAGTGCACAACTATTACTTGGAGTCAAAATcgtcattttgttgtttcgtttGCAAGCGGGACTTTCTTACTGTTAAGCTATTTGACGAGCATTTAGTTGAACATCCCGCCGAATGTTTTACATGTCACAAAAAGTTCACTAGATGGAAAAACTTTATGGTTCATCTGAAGCGTCATCTAGGTTGGAAAGACTTTGCATGCACTTATTGTGAAAAGAAGTTCGTCATACGAAGCGCTCTTGTGGAACATATGCGAATGCATACTGGCCAGACACCACTTAAATGCAAGATCTGTGGAAAGAGCTTCAAGCGTTATTCGAACCTAACACAGCATCGTAAGCGGCATGGCACCAAAATCAATCGTTCGAAAgagtatgtttgtttttgtggaGAGGTTTTACCATCGAAAGCTCGCTTTATCTGGCATAAAGAGACACACGATCTAAAGCCAAAATGCTGTCCTTACTGTAGAGATAGGTTTGTGCATGCGAATAGTTTGAGACGTCATATACGACTAGCACACTCTGATAAGTTTGATTACACCGAACCTATGGAGTGTCCCATGTGTAAGCAAATTTATGCAAAATCCAGCATCAAGGCTCACATGGCGACGCACTCAATGGATACGCAGCACGAGTGCCTCATTTGCAGCAAATCATTTAGTACGAAATGGAATTTAAAGATACACAACTGGGTGCACGCCAATCGCACTACAAAACCTTTTAAATGTGAGCAGTGTGTAAAGGCATTTGTGCGGGAAGTCGACTACAACAATCACATAAATTCGCACAAACAAATTAAACCCTACACTTGTGAACATTGCGGCTGCAAATTTATCCGCAAGTATAACTACATCCGGCACAGACGCGAGCACCATGGAAACAAGAAGTTCACCTGTGATCTCTGCGGCAAGCTCTTCCACCGGCACTACTATCTGATCGAGCATCGGCGCATCCACACTGGCGAACGACCATTCCAGTGTACAATATGTGGAAAGAGTTCCACAACAAAGACTAACCACAACAAACATCTGAAGATTCATCATTCACGGGATCCCTTCACCTCGGAGGCgtaa
Protein Sequence
MGGNVQCPVCTLFLLPGMNLSDHLETHPKEQVIKALVQMSLKTETTESITPDTPKKANKFSFAEAADETSHPATEDERHSPISEISDSASNSAPGFVEPAATKRTEKESNNTLLPAAPPPNVLNRQGVYMFENNSSSSNSSSSTFFGPLTPYYHQQQQQQQQQQQQQQQQQQQQQQQQQNNHHHHHHQHQQLQQQHQPHEDLNHQQHQQHVNHNYQPYHNLSQGGNINFTGHGPTHPPMRLFSYQPTPKPLQPPPAYGAAISQLRSQNSQNLMSNTTHRPLYSPGNYTLPPSGSISASTSSTPSRLPPPLPPPPLNQRYQSNFETMETAFTDAVDTSAISPRRTSMTPPIRPPPQLYRSPQSSSNAQFSRQSSSPYPVMSGSPSVLRFAESPVTAHYLERENGDFIVQETPKHVVECVEKDDGEFSVIERVYHMPPSVVQINEDEEEELSEHGSNSEDVKLIEDDHPNENWTIGESSDQGQTLEKPEKTPKKSGITVLSDVQLDLSEYLDLMGNIIASGKVAKNRSELIKVEKFEPEEVKQEETICLDDNDNSVASMNTNQKCDETEEEKLELSNESSVYCPLPLPPAFSKTESCATSSLVVPVTTSVIRLAATVNAKPSTLVTAATNTEEPIHKESSNTLTTGKVEEQMEISDVEEEKPTTSLKIEIESTSNSKPSYMDVNLVETSTPTNKTEEALKTTSLEEAPIEDISTQPTNELPDKTESRNVNLPINSFHQTLKRPIKKGPKKLIIKPKSKDASTSQAITEKTATSISDPTPSIQMPMPISSTSTETSNLIQQQQQQKEEVTPKDSSPRDELNSIKIESLSSVTSDPILLRPLLADADEKLPPEDDAQLQPQPQPSTSNSIVSEEKRGTEEFHLEGQKPTADLTAFIDECLKKEEEEEHPMHSIFGMDIRATEETLSNALTPPPPTPEFPSPSLFAKPLTTTTSENLSIPESMLLDGSNLHEPDDHQLHHDQQQEHQQSNSNFVEYPFSFLYGGEANHEEEDDKHNIPAPIYCTEDFNKYSVSTSGGNSASCTWYQSQSSENDFEMDGKGSYLDLDSCKRSTSFAAATEGSMPTSDALNIRTDEKMPAKGEISEQESNCGVENSWSQPLYNEFAVRFPNPYQNFMSNHESWSQDHYFRPQDLSSSVETKNFPLHSTEEPSAVIDALPSTSKRKNKETIAKLPRKKNFQCTHCNTHFPLLKEKNAHMIKQHGYKRVNRRLIRDPPTSTVTTATLNAVDPAGAASLLLGLDGNARPSLPVGEDEDSKAAIVKIEQENQDCKNKNVSNLAISSKKVTSSTSAANSATNVSRTKYDSMRARDNRMLINFNLSALNVKNEGEVHNYYLESKSSFCCFVCKRDFLTVKLFDEHLVEHPAECFTCHKKFTRWKNFMVHLKRHLGWKDFACTYCEKKFVIRSALVEHMRMHTGQTPLKCKICGKSFKRYSNLTQHRKRHGTKINRSKEYVCFCGEVLPSKARFIWHKETHDLKPKCCPYCRDRFVHANSLRRHIRLAHSDKFDYTEPMECPMCKQIYAKSSIKAHMATHSMDTQHECLICSKSFSTKWNLKIHNWVHANRTTKPFKCEQCVKAFVREVDYNNHINSHKQIKPYTCEHCGCKFIRKYNYIRHRREHHGNKKFTCDLCGKLFHRHYYLIEHRRIHTGERPFQCTICGKSSTTKTNHNKHLKIHHSRDPFTSEA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00427562;
90% Identity
iTF_00894249;
80% Identity
-