Basic Information

Insect: Epinotia brunnichana
Gene Symbol: IBTK
Assembly: GCA_963854355.1
Location: OY977950.1:12124707-12148424[-]

Transcription Factor Domain

TF Family: BTB
Domain: zf-C2H2|ZBTB
PFAM: PF00651
TF Group: Zinc-Coordinating Group
Description: The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 6.8e-13 4.2e-10 41.8 0.0 6 79 545 616 540 630 0.85

2 3 2.9e-13 1.8e-10 42.9 0.0 6 107 739 844 736 847 0.85

3 3 8.5 5.3e+03 -0.4 0.1 81 106 850 875 843 878 0.86

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	6.8e-13	4.2e-10	41.8	0.0	6	79	545	616	540	630	0.85
2	3	2.9e-13	1.8e-10	42.9	0.0	6	107	739	844	736	847	0.85
3	3	8.5	5.3e+03	-0.4	0.1	81	106	850	875	843	878	0.86

Sequence Information

Coding Sequence: ATGAGTAAGAACATAGATGTGGATTGCACACGCCGGTGCAAATCTAGACGCCATGGACAAGCGCTCACAGGAGCCATTACAAAAAGATCAGTCAGTGACGAAGCACTGGCCAGCTTCATCAAGGCAACATGCGCTAACTTCATACAGGCTTTTGATTTGGAGGGTCGTACAGCTCTGCACATGGCATGTTCCCGCGGCCGCGCGGGTCTTATGGAGTGGCTGCTCCGCCACTCCACTGAAGCTTTCATAAATGCCCGAGACAGGGAGTCTGGGTACACACCACTCCATCGGAGCATCTTCTATGGGCAAATACACAATGCTGTTGCTTTGATGAAAATTGGCGTTAACACCGACATCGTCGACAAGGACGACTACAGAGCGCTAGAGCACGCCATGCTGGACCGGCAGTACATGTACAAGCACGCCGGCGTCGAGCCAAGCGACGTCTACGTGTGGGGCAGCAACTGCAACTATACGCTGGGCACGGGCACGCAGCAGCCTCGCAGCGTGCCGGAGCTGCTGGGGAGCTTCAGCCGCGCCAACGCGAGCGTGCGACAGGTGTGCCTGGGCAAGTTCCACAGCATCTGGCTATGTGGCGGTGAAGCCTGGGCGTGCGGGCAGGCGGGGCGCGCCGGGAGCGCCCGAGGCACTCTGTTACGCCCGGCGCAATTGAAGCTGCATGAACCAGTAGTGCAAGTCGCCGTGCTGCTGGACTCTACTGTGTTCCTCATGCAGAGCGGGACGgtccTCCAATACACGTTAAACAGCGCAGACACCTCTCCGATCGCAAACAGCTCGTCCCTAAAGTTGCCCTCAACGAAGCCTATCTTGAAACTATCGTCCCCGCTAGGGCTGTGCTCGGGCCGCGCACACGCAGCAGTATGGAACACCCACGCGGTCTACACGTGGGGGGTTAACTGGGGACAGCTGGGACATTCGCAAGAGGACAAGGTCGTCGCTGCACCCAAACGGGTGGCGATATCCATGAACAATAAAGAAGAAACGGGCATACAACTAGTGGGTGCGGGCGACGCGGCCACGGCTATAGCCACGAGCCGCGGCGACGTATATCTTCTACACAAACACATCTGCAAGAAGATCGCCATCAAACAGATAAACCTGCGGCAAGTGTGCGTGGAGGCGAAAGTGAGCGATACAGGAACGTACTCGCGCGTGACCGTGCTACTGCTGACCAACGTCGGTCAACTCATGCTGTGGCAGGACACCACCAACCAACTCAccagATGCGTCTTTGGCTTGAGCCACCAGATAATCATAACCAACGTGGCGTTAACCCACGACGCTCTCTACTTCACTACCAAATACGGCGAGGCGTTCATTGGCTACATCTCGCGCAAGACCACGCCCACCGCGCCGCAGCCAATCAGGAAGGAGAAGGAGCGAGACAACAATAAGAGCGCGCTGGTCAAGTTTCTTGAGAAGGATGATTGTTCGTCAGTTCGGATTGTGAAGATACCGAACTTGCATAGAGCGGTGTCGATCGTGGTGGATAATGAAGGACTGAACTTTGCATGTCTTCAGATTAAACCTACGTGTGGACTCACGTCACTGCCCGAGCTCTCGCCCACCAGTTTGCCCAAACACATGGAATCTCTCATGGAAACTGCTGCAGAAGACGACATCCTACATGACGTTATTTTcaagGTTGGCACTAAACTCTACCCAGCCCACATTTTCATAATCGCCTCAAGCAGCGAGCATCTCTACAAATTGTACCAGGATAACATAAGGAACGCGGAGGATAAGCCTGTCATCAACATAGAGATGCACCCAGAAGTGTTTGAAAGGATATTGAGATACATGTACAGTGGCACATGTGATGTGGCCGAGTTGGGGCCTTGCAGTTTGAAGATAAGGAGGGAATATCTGAATAGCTTGAAGAAGGAAAAGGATGTGGAAGTTGAATTAGAAGATCCGAATATAATTGACAACGCGTCAGAAATGTCAGCGTTTGAAGTGTACAAACACCAGGAGAACAGAAGCAAGAAGGCACGCGCGCGGCGCAACGTCGAGACGCCGCCGCGGCAGGACCTGTACTGCGACCCGGTCCGGCTCGTGCAGGCCGCCGCCAAGCGGCTTCACGTCATAGGGTTGCTTAAGCTGTTGGAGAAATTCTTCTACAGAGACGGCACCATCTGCCTAAAAGAGAGCGCAACATACTCCAAAAACCCTCCATTATACTGGGAGCGCAGCAGTCACGAAGAGTTAATTGACACGAGCGTGGTCGCCAAGGACGGCGCGCTCATACCGGCGCACAAGTGCGTGCTCGCCGCGCGGCTCGAGTACTTCCAGGGGATGTTCATGCATTCTTGGACCGAGAGTAAACTATCATCAAAAGTGACTCTACCCATCAACCACGGCATTCTTCTGCCAGTCATAAACTTCCTTTACACAGATTCATGTCCAGAAGTAGAAAACTCAGACAGCATAGACTTCATATGCAGCATGCTCATTGTCGCCGACCAACTCTTCATAAGTCGCCTCAGAGAGATGTGTGAGGTCGCCCTTTCAAACCTCATCACACTGCGGAATTGCTCAGAGCTCTGCCAATTTGCCCACACTTACAACGCAACTCAGCTAAAACAGTGCTGCATGGAATTCATATCACTGAATATCTCAAGCATACTCGAAAGCAAATCGCTTGAAGTGTTAGAAGAAACGCTGCTTGAAGACATCTCCAAGTACTACTGCAAGTTTAACCCTATCATGTCTTCTAGAGTCATTACGCCCTTCTTCAACGCACCAGACGATGAAGTTGTTCATGAATGTGCTAAAAACTGCCCTGTCGATTTAACCGTTATTGACGAAGATCTGAAAAAGGATGACAGTGTCGTAGAAATAAGTAAAAAGAAGAGATATAAGAAGATCGAATACACTGAGAGTGAGAAAAGTAGGATGAGGTATGAATCCGTCAGTTCTGTGACGTCATTAGACCTGTCGAATGATGTATCGGGTGATGTCACGCTGTCTTTGAGTAGTATATCTATAGAAACTGAAAAGAGTTCCAAGGTGAAGAAGGATAAATGGATCGAAGTGCCATCAGCGCAGCAGAAACAACAGAAAGTCGTCCTAGCGAGGCTTAAAGCTTTAAGTAGTGCTAAAGAGATCCTAAACGAAACTCCAGTAGAATCCTTCACTAAGCTAACTAGAAACAGTTCCTCAAGTGCCGTTAACACCCCAGTGACACCTTCCTCATCACGCATGTCAGTGTCGCCGAAAGAATCCCCCATAGCGGAGATGGCTTGGGGCTCACCAGGCAACCTGGTCATTAACCACATAGGTCCCAAGCTCTCCCAAAAGCAGAGAAAAAAGTTAGCCATGGAAGGCACCTGTTCCCCTCAAAACTTGTCTCAGTACTTGGATGGGAAAGGAGTAGGCAGCTCTCCAGACAAGCCAAGGAATCCGTGGAAGATTGTGGAAGTGCCGGTGGCTAGCAGCAGTCCTAAGCAGAAGGAGAAGGCCATGGGATTCAACCAGATCCTGGCTGATCAGAAGAAGCAGAAGGATGACTCGTCGAGGATCATGACCAAACCGCTGCTTTTGACACAGctGGAGGACAAGGCCATAGAGGAGCTGGAGAGGTTTTACAATGTTCATGAACTGGACGATGAGCTCATCACGGTGCGGCGCATCGAGCTGCAGGTGTCCTCGCCGCAATGGATACACACTGCCAAATGA
Protein Sequence: MSKNIDVDCTRRCKSRRHGQALTGAITKRSVSDEALASFIKATCANFIQAFDLEGRTALHMACSRGRAGLMEWLLRHSTEAFINARDRESGYTPLHRSIFYGQIHNAVALMKIGVNTDIVDKDDYRALEHAMLDRQYMYKHAGVEPSDVYVWGSNCNYTLGTGTQQPRSVPELLGSFSRANASVRQVCLGKFHSIWLCGGEAWACGQAGRAGSARGTLLRPAQLKLHEPVVQVAVLLDSTVFLMQSGTVLQYTLNSADTSPIANSSSLKLPSTKPILKLSSPLGLCSGRAHAAVWNTHAVYTWGVNWGQLGHSQEDKVVAAPKRVAISMNNKEETGIQLVGAGDAATAIATSRGDVYLLHKHICKKIAIKQINLRQVCVEAKVSDTGTYSRVTVLLLTNVGQLMLWQDTTNQLTRCVFGLSHQIIITNVALTHDALYFTTKYGEAFIGYISRKTTPTAPQPIRKEKERDNNKSALVKFLEKDDCSSVRIVKIPNLHRAVSIVVDNEGLNFACLQIKPTCGLTSLPELSPTSLPKHMESLMETAAEDDILHDVIFKVGTKLYPAHIFIIASSSEHLYKLYQDNIRNAEDKPVINIEMHPEVFERILRYMYSGTCDVAELGPCSLKIRREYLNSLKKEKDVEVELEDPNIIDNASEMSAFEVYKHQENRSKKARARRNVETPPRQDLYCDPVRLVQAAAKRLHVIGLLKLLEKFFYRDGTICLKESATYSKNPPLYWERSSHEELIDTSVVAKDGALIPAHKCVLAARLEYFQGMFMHSWTESKLSSKVTLPINHGILLPVINFLYTDSCPEVENSDSIDFICSMLIVADQLFISRLREMCEVALSNLITLRNCSELCQFAHTYNATQLKQCCMEFISLNISSILESKSLEVLEETLLEDISKYYCKFNPIMSSRVITPFFNAPDDEVVHECAKNCPVDLTVIDEDLKKDDSVVEISKKKRYKKIEYTESEKSRMRYESVSSVTSLDLSNDVSGDVTLSLSSISIETEKSSKVKKDKWIEVPSAQQKQQKVVLARLKALSSAKEILNETPVESFTKLTRNSSSSAVNTPVTPSSSRMSVSPKESPIAEMAWGSPGNLVINHIGPKLSQKQRKKLAMEGTCSPQNLSQYLDGKGVGSSPDKPRNPWKIVEVPVASSSPKQKEKAMGFNQILADQKKQKDDSSRIMTKPLLLTQLEDKAIEELERFYNVHELDDELITVRRIELQVSSPQWIHTAK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00680717;
90% Identity: iTF_00658534; iTF_01072659; iTF_00659550;
80% Identity: -