Basic Information

Insect
Empis livida
Gene Symbol
Aef1
Assembly
GCA_963932195.1
Location
OZ010647.1:37357985-37358731[+]

Transcription Factor Domain

TF Family
zf-GAGA
Domain
zf-GAGA domain
PFAM
PF09237
TF Group
Zinc-Coordinating Group
Description
Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 4 0.011 57 4.1 0.1 22 48 99 125 89 129 0.84
2 4 5.5e-06 0.028 14.7 0.1 21 52 126 157 122 158 0.89
3 4 0.0054 27 5.1 0.0 21 51 154 184 152 185 0.87
4 4 0.00014 0.69 10.2 0.1 21 47 182 208 179 213 0.89

Sequence Information

Coding Sequence
ATGActaattgtgaaatattaattgttacCACAAGTGATGGTAATAGATCACATATTCAAATTCCGGTATCACGTACAATACCAACATCAGCCACACCACGTTCAATAATATCAActgtaattaataatagtaatttagtAAATGCTGCTGCCGTTGCTGCAACATCAACACCATCatctataattaataataataattcctctttaaatgaaaatactaCTAATAATACTGTACAAATGCCAACtgaaatgattataaatagTAGAACAGCAAGAACAGCTAATGGTTCATTAGATAAACCATTTCAGTGTAATGTTTGTGAAAGAAAATTCCGACAATTGAGTACATTAACAAATCATGTAAAAATTCATACTGGTGAAAAACCTTTTAAATGTTCAATAtgtgaaaaatgttttagGCAGTCAAGTACATTaacaaatcatttaaaaattcatactgGTGAAAAACCATTTGGGTGTACGTATTGTGGAAAACAatTTCGACAATTGAGCACATTAactaatcatttaaaaattcatactgGTGAAAAACCATTTGAATGCGCTGTTTGTAAGAAACAGTTTCGTCAATCAAGCActttaaataatcatataaaaattcatgttATGGATAAACTATATATACCATTTGAGAttaaagaagaagaagaaggctga
Protein Sequence
MTNCEILIVTTSDGNRSHIQIPVSRTIPTSATPRSIISTVINNSNLVNAAAVAATSTPSSIINNNNSSLNENTTNNTVQMPTEMIINSRTARTANGSLDKPFQCNVCERKFRQLSTLTNHVKIHTGEKPFKCSICEKCFRQSSTLTNHLKIHTGEKPFGCTYCGKQFRQLSTLTNHLKIHTGEKPFECAVCKKQFRQSSTLNNHIKIHVMDKLYIPFEIKEEEEG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2