Basic Information

Insect
Empis livida
Gene Symbol
L
Assembly
GCA_963932195.1
Location
OZ010646.1:38746236-38759572[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 17 7.4e-06 0.00044 20.7 1.7 1 23 225 247 225 247 0.98
2 17 0.61 37 5.2 5.8 1 23 253 275 253 275 0.98
3 17 3.2e-07 1.9e-05 25.0 3.1 1 23 281 303 281 303 0.99
4 17 2.7e-05 0.0016 18.9 0.2 1 23 309 331 309 331 0.98
5 17 0.49 30 5.5 0.1 2 23 401 424 400 424 0.87
6 17 0.025 1.5 9.6 0.4 2 23 450 472 449 472 0.94
7 17 0.11 6.6 7.6 0.4 1 23 588 610 588 610 0.95
8 17 0.0016 0.095 13.4 2.2 2 23 618 639 617 639 0.96
9 17 0.0042 0.25 12.0 1.7 1 23 647 671 647 671 0.92
10 17 2.8 1.7e+02 3.1 0.9 1 23 706 729 706 729 0.96
11 17 0.0019 0.12 13.1 2.9 1 23 762 784 762 785 0.96
12 17 0.0014 0.084 13.5 4.6 2 23 1001 1023 1000 1023 0.96
13 17 0.16 9.8 7.0 0.1 1 23 1029 1051 1029 1051 0.92
14 17 0.28 17 6.3 0.7 2 23 1059 1080 1058 1080 0.95
15 17 3.8 2.3e+02 2.7 0.5 2 23 1170 1191 1170 1191 0.93
16 17 0.0076 0.46 11.2 0.1 1 23 1201 1224 1201 1224 0.97
17 17 0.04 2.4 8.9 0.4 1 23 1231 1253 1231 1253 0.96

Sequence Information

Coding Sequence
ATGGCCCTAAAAATGTTATATCGTGGTCCGAGCTCAAGATTGGaaactttaattgaaaaaattcagGCAACTAAAGAAGTTAATactgACTTATATTCAACACACACATCATCAAGCTATTCACCATCAATGTCTGAGGGAGCAGCGACACCCAACTCCTTAATACATcattcttcaaatttattacatccaacaacaaatttacataattcagAAGTGGATGGAGATGGTAATAATCGCCTTAGGAGTAGCAacaatactaataataataataataatcaccttacaaataataagaatattcGTAGACGACGTCAACTTTGTCGAAATAGTTCAACCGCAATTGAAGGTGTTAATGACATTAATGAGGATGAATATGAAATTGATGGTGGTGATGGTAATGGTGCTGAAGATGAAATACATGAAGCAGATGATGGAATTGATTCGGGTAatgaaagaattaaaaataatgatgaaaatgCTATAAAAGAATGTggtataaaagataaaaaaaatataagtcgAAATAGTGAAACTggtaatagaaaaattacaactaaattacgaaaaattgATAAGGAATCAACAGGAAATAAATCTGCAAATTCTGGTAAGATGACAGGAAATGGTGTTGAGGGTGGAACAATTAAAAATGGTACAACAGATGGATCGTATCAGTGTCAGTTTTGTGATAAATCATTTCCACGTCTTGGTTATTTAAAGAAGCATGAACAAAGTCATGCTGAACATTTACCATTTAAATGTGATTACTGTGCCCGTTTGTTTAAACACAAACGTTCCAGAGATCGTCATACAAAATTACATACAGGTGACCGACGTTATCGTTGTCCACATTGTGAAGCAGCATTCTCAAGAAGtgatcatttaaaaattcatatgaaAACTCATGATAACCAAAAACCATTTCAATGTACGGTATGTAATCGTGGTTATAATACTGCAGCAGCTCTAACATCACATATGCAGAATCATAAGAAACAAGCAGCACTATTAGGAACCGGTTTACAACCATTAAATTATAGTCCTCGGTCGACTGGTTCGGGATCAAGTAATGGTAGTTATAATACAAAACGTAGATATGCAACAGTACCGCTTGCAGTAGCTACTGCTGGTGATAATAATAACAGTTCAACAAATCATATTggtgattataataaaagacAGCGATCAACATTTATTTCTTGTGCTTATTGTACAAAATCAGATTTTGCAACATTGGATCAATTAAACAACCATATTCAGGCAATGCATGAAAATGTCTtaacaaaaactaataaagattcaccaaaacatcagcattcgttgaatttaccaaattttcaattaaattgtgaatattGTACAatgaaatttccaaatattccTACAATGTTTCAACATATGCGTGCTACACATATTGACAGATTGTCCAGTCcaaattcatattttgaaaatttcaaccGTTTGGCTGCTTCTGGTACATTTAGTCCAAGATTAATAACTAGAGCTGTTACACCAAAAAGTCGTTTTGACGATAATATTGctggtataaaaattaaacgtGAAGAAATAAGTCCaaacaatttattagataaaaatgataatataacAGGAGAGAAAGATGAAGAGCAAATTGGACCAACTGATTTAAGTCAACCCAAAAAACGTACACAAACCCCTTTTGATAGAACAACACCTACAGTTGGACCAACAGCAAcagatttattagaaaaacatTATCATCAGCAAGGGGCAGGtgcatttttatgtaatcaatGCAATGCTGCACTACCAGATTTTGAAACATTTCGTAATCATTTGAAAAGTCATATTGCACACGGTATGAATTTGGTTTGTCATCATTGTGGATTGACGTTGCGAGATCAAAATGAATACGAACGTCATACAATTTCACATTTTCTTATAACAAATTCTGAATTTTCGTGCACAAACACCTGCCAAAAAACTTATTCAAAAACTGAAGATCTTCAAAAACATCTTTACGAAGATCATGTTCAAATCATGTACAAATGTTCATTATGTTCAGATCTATTTGATACGAAAGTTGCAATTCAAGTGCATTTCGCTTGTGCCCATTCGAATGAGACGAAAATATATCGTTGTTCTGCTTGTATGGAACAATTACGAACGGAAAAAGACTTTACTATTCATGTTAAGACTAGACATCAAACTAGTAGCGGTTCAATTCAGTGTATGTTTTGCAGAGCAGTTTGTTCGTCTGAATTAGAAATGCATTTTCATTTAGCTGCACATGCCAGACAATTTCGTTGTCCATCATGTCCGGAAACTTTTCATGTTGAATTTCTACTTGATCGTCATATGCAAACGCATCACAGTACCGGTgttaataatcaaaaagatTGTCATCCGCCAACAGCAAGTCCAGTCCTAGCAGTAAATGGTCCAaatcaactttttttaaatgctgCTGCGCAATACGCCAAACaacagaataataataataatattttagattatcaCGCATTTGCGgcaacagcagcagcagctGCAGGAAAgggaatatttcaaatgacaaATTCTGTAAATGGTGCAACCGCAGGAACGAAATTTTATAGTCCACTTCAAGttgatacaaattctgttAAGCATCCAGCTTTGCTATATGGATTAGGTCAAAGGTATTTTGATGCTGGTAAATCTTTATTGGATACTATGTACAATTATCAACAAGAAAAATCAGCGGCAGCTGCTGCCGCTGCTGTAGAATCAGCGGgtcgtaatttttttgttagtccTAGAAATGGTTCAGGAAtcgaaaataataacaatactagtaataataataacaatctAAAAGATTCTGCAAAACGTATACattctgaaaataataaagtttcaGATAGAAATATGCAAAGTGGATTCAGCTGCGGAATATGTGAGCGAAATGATTTCCGCACAGAAACAGAAGTTCATTCACATCGAAAAAttgttcataatttaaaaactggtGTTAGCTTACGATGTGCTTATTGTAGTGGTAATTTTAAATCCCGCAGTGAGTTAGAACATCATATGAAAACATGTCACAATTCGACTGGTAAACATAAATGCTTAATTTGTGATGAAATATTTCCATCTCCGGCGATTTTAGCTGAACACAAATTACAACATTCTAAAGTTGGTCAATCTGGAAAATGTTCACATTGTTCTTTAGCTTTAAATGATGTGTCAGCTTTTAAAAGTCATTTATCTGACCACAATGTCGAAGGTCAAATTCCAGTACAATGTATTTGTTGTCGTCAAACTTTAAATTCTGATTTTGAAATAGGTTTACATGCAAAaTTTCATACAAAATCTTCGGGAGCTCCAGAAAATGCTTGTGCTCTATGTCTAGAAGCAATTCCAGTCACTTCTGAAGCAAAAGTTTGCGAGAAATGCTGtcgaaaacataatttaacaacaaaatttacgaATATGCGGTTCGACAATCATTCGCATAAAACTAATAACGTATTCATAGAGAATCGATGCAATCTCTGTAAAATGATTCTGCCTCATGCACAAAGACTGCAAGAACATTTGGTTGAGCATACTTTTGTTGGCTGCGAGGAACGTGGTTATTCGTGTTACATTTGTTCGGCTGTTTTCACAATTCCTACTGGCTTATTGAGTCATATGTCTTCCGAACATGGTCAAAATGCTCGCCCTTACGATTGTAATCTATGTACAGAGAAATTCTTTTTCCGTGCCGAATTAGATAATCATTTAATTGAACATGAAAATAAAGGACCAGTTCATTTAGAacagaaatatgaaaataaccAGCAACGTgacaattcaattttaaaagacGAGAAGTCTAAGGAAATAGTAAATGAATCAGTAGAAGAACTAAAAGCAGAAGTGAAAATGGAAACAGTTGAAGAGGCTAATAATGACGATGAAGAAGAATACATTGAGGTTGAAAAAGTAGCTGAAgctatagaaaatattaacaacgataaaaataatgaataa
Protein Sequence
MALKMLYRGPSSRLETLIEKIQATKEVNTDLYSTHTSSSYSPSMSEGAATPNSLIHHSSNLLHPTTNLHNSEVDGDGNNRLRSSNNTNNNNNNHLTNNKNIRRRRQLCRNSSTAIEGVNDINEDEYEIDGGDGNGAEDEIHEADDGIDSGNERIKNNDENAIKECGIKDKKNISRNSETGNRKITTKLRKIDKESTGNKSANSGKMTGNGVEGGTIKNGTTDGSYQCQFCDKSFPRLGYLKKHEQSHAEHLPFKCDYCARLFKHKRSRDRHTKLHTGDRRYRCPHCEAAFSRSDHLKIHMKTHDNQKPFQCTVCNRGYNTAAALTSHMQNHKKQAALLGTGLQPLNYSPRSTGSGSSNGSYNTKRRYATVPLAVATAGDNNNSSTNHIGDYNKRQRSTFISCAYCTKSDFATLDQLNNHIQAMHENVLTKTNKDSPKHQHSLNLPNFQLNCEYCTMKFPNIPTMFQHMRATHIDRLSSPNSYFENFNRLAASGTFSPRLITRAVTPKSRFDDNIAGIKIKREEISPNNLLDKNDNITGEKDEEQIGPTDLSQPKKRTQTPFDRTTPTVGPTATDLLEKHYHQQGAGAFLCNQCNAALPDFETFRNHLKSHIAHGMNLVCHHCGLTLRDQNEYERHTISHFLITNSEFSCTNTCQKTYSKTEDLQKHLYEDHVQIMYKCSLCSDLFDTKVAIQVHFACAHSNETKIYRCSACMEQLRTEKDFTIHVKTRHQTSSGSIQCMFCRAVCSSELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQTHHSTGVNNQKDCHPPTASPVLAVNGPNQLFLNAAAQYAKQQNNNNNILDYHAFAATAAAAAGKGIFQMTNSVNGATAGTKFYSPLQVDTNSVKHPALLYGLGQRYFDAGKSLLDTMYNYQQEKSAAAAAAAVESAGRNFFVSPRNGSGIENNNNTSNNNNNLKDSAKRIHSENNKVSDRNMQSGFSCGICERNDFRTETEVHSHRKIVHNLKTGVSLRCAYCSGNFKSRSELEHHMKTCHNSTGKHKCLICDEIFPSPAILAEHKLQHSKVGQSGKCSHCSLALNDVSAFKSHLSDHNVEGQIPVQCICCRQTLNSDFEIGLHAKFHTKSSGAPENACALCLEAIPVTSEAKVCEKCCRKHNLTTKFTNMRFDNHSHKTNNVFIENRCNLCKMILPHAQRLQEHLVEHTFVGCEERGYSCYICSAVFTIPTGLLSHMSSEHGQNARPYDCNLCTEKFFFRAELDNHLIEHENKGPVHLEQKYENNQQRDNSILKDEKSKEIVNESVEELKAEVKMETVEEANNDDEEEYIEVEKVAEAIENINNDKNNE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00644494; iTF_01297856;
90% Identity
-
80% Identity
-