Rlae032601.1
Basic Information
- Insect
- Rhamphomyia laevipes
- Gene Symbol
- L
- Assembly
- GCA_963920725.1
- Location
- OY987259.1:25045448-25062838[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 17 7.4e-06 0.00086 20.7 1.7 1 23 229 251 229 251 0.98 2 17 0.62 72 5.2 5.8 1 23 257 279 257 279 0.98 3 17 3.2e-07 3.7e-05 24.9 3.1 1 23 285 307 285 307 0.99 4 17 2.7e-05 0.0031 18.9 0.2 1 23 313 335 313 335 0.98 5 17 0.39 45 5.8 0.2 2 23 416 439 415 439 0.87 6 17 0.025 2.9 9.6 0.4 2 23 466 488 465 488 0.94 7 17 0.11 13 7.5 0.4 1 23 610 632 610 632 0.95 8 17 0.0018 0.21 13.1 0.8 2 23 639 660 638 660 0.96 9 17 0.022 2.5 9.8 0.9 1 23 668 692 668 692 0.92 10 17 3.9 4.6e+02 2.6 1.0 1 23 727 750 727 750 0.96 11 17 0.0019 0.22 13.1 2.9 1 23 783 805 783 806 0.96 12 17 0.00026 0.03 15.8 2.4 2 23 1026 1048 1025 1048 0.97 13 17 0.068 7.9 8.2 0.5 1 23 1054 1077 1054 1077 0.93 14 17 0.12 14 7.4 0.6 2 23 1085 1106 1084 1106 0.96 15 17 3.9 4.5e+02 2.7 0.5 2 23 1194 1215 1194 1215 0.93 16 17 0.014 1.6 10.4 0.0 1 23 1225 1248 1225 1248 0.97 17 17 0.041 4.7 8.9 0.4 1 23 1255 1277 1255 1277 0.96
Sequence Information
- Coding Sequence
- ATGGCTCTTAAAATGTTATATCGTGGTCCTAGTTCAAGATTGGaaacattaattgaaaaaattcaagCTACTAAAGAAGTTAATACTGatttatattcAACTCATACATCATCGAGTTATTCACCATCAATGTCTGAGGGAGCAGCAACACCTAACTCCTTATTACATCATTCACAGCATTTATTATATCCTACCGTTAATAATTTAGAGGTTGgagaaaatgatgatgataataatcgCCTTAGgagtaacaataataataataatcataaccTTACAAACAATAAGAATTTTCGTCGACGACGTCAACTTTGTCGAAACAGTTCAACTGGAAATGAAGTTGGTGTTGATGACATTAATGAGGATGAATATGAAGTTGATGGTAGTAATAATGGTGCTGATAATGAAAATCATGAAGAAAATGATGATGGTATTAATTCGGGTAATGAAAGAGTTAATAATGATAGTAATATAAAAGAACCGATtggtaaaaatgataaaaaaaatattataaatcgaaATAGTGAAAATGTTGTTAATAGAAAAGGTACAACGAAATTACGTAAAATTGATAGAGGTGAATCAACAGGAAATAAATCTACATCAAATTCTGGTAAAATAACAGGAAATGGTATTGATGATACTGGTACAATTAAAAATGGTACAACAACATCAGATGGATCATATCAGTGTCAATTTTGTGATAAATCATTTCCACGTCTTGGTTATTTAAAGAAGCATGAACagaGTCATGCTGAACATTTACCATTCAAATGTGATTATTGTGCTCGTTTGTTTAAACATAAACGTTCCAGAGACCGTCATACAAAATTACATACAGGCGACCGCCGTTACCGTTGTCCACATTGTGAAGCAGCATTCTCAAGAAGtgatcatttaaaaattcatatgaaaACTCATGATAATCAAAAACCATTTCAATGTACTGTATGTAATCGTGGTTATAATACTGCAGCAGCTCTAACATCACATatgcaaaatcataaaaaacaagCAGCACTTTTAGGTACTGGATTACAACCACTAAATTATAGTCCACGTTCAACTGGTTCGGGTTCGTCTAATGGTAGCTATAATACAAAACGTCGATATGCTACAGTACCACTTGCAGTAgtagcagcaacaacaacagctgcTGGCGTTGATAGTAATAATAGTCCAACAAATCATATTGGTGGTGGAGGTGGTGGTGATTATAATAAAAGACAACGTTCAACATTTATTTCATGTGTTTATTGTACAAAATCAGATTTTACAACATTGgatcaattaaatattcatattcagGCAATGCATGAAAATGTATtgtcaacaaaaattaataaagattcaCCAAAACATCAACATTCGTTAACAAtaccaaattttcaattaaattgtgaaTACTGTACAATGAAATTTCCAAATATACCAACAATGTTTCAACATATGCGTGCCACTCATATTGATCGTATGTCCAGtccaaattcatattttgagaattttaatcgTTTAGCTGCATCTGGTACATTTAGTCCAAGATTATTAACTGCTACGCCTAAAAATCGTTTTGATGATaatggtggtggtggtagtTTGAAAATTAAACGAGAAGAAATAagtccaaataatttaataatggataaaaatgataatttagtaAGTGAAAAGGATGAGGAACAAATAGGTCCAACTGATCTGAGTCAACCGAAAAAACGTGTACAAACTCCATTTGATAGAAATACACCGACACCATCAACTGGACCAATATCAGCagaattattagaaaaacatCACCAGCAACAGCAGCAAGTAGGAGCAGGCGCATTTTTATGTAATCAGTGTAATGCTGCTTTACCAGATTTCGAAACATTTCGAAATCATTTGAAAAGTCATATTCAAGGTATCAATTTAGTTTGCCAGCATTGTGGATTGACATTACGCGATCAAAATGAATACGAACGTCATACAATTTCACACTTTCTTATAACAAATACGGAATTTACGTGTTCGAGTAgctgtcaaaaaatatattcaaaaactgAAGATCTTCAAAAACATTTATACGAAGCACACGTTCAAATTATGTACAAGTGTTCGTTATGTTCCGATCTATTTGATACAAAAGTTGCTATTCAAGTACATTTCGCTTGTGCACATTCGAATGAAACGAAAATATTTCGTTGTTCAGCTTGTATGGAACAATTACGAACGGAAAAAGATTTTACTATTCATGTTAAAACTAGACATCAAACTGGTAGCGGTACAATACAATGTATGTTTTGTCGAGCTGTTTGTTCATCCGAATTAGAAATGCATTTTCATTTGGCTGCACATGCCCGACAATTTCGTTGTCCATCATGCCCAGAAACTTTTCATGTTGAATTTTTACTTGATCGTCATATGCAAACACATCATAATACTGGTGTGAATAATCAAAAAGATTGTCATCCGCCATCAGATAGTCCTGCTCTAGCAGTAAACGGTCCAAATCAACTGTTTTTAAATGCTGCTGCGCAATACGCGAAACAGCAACAgcataacaataacaataatattttggaTTATCATGCATTTGCGGCATCAGCAGCTGTAGCTGCTGGTAAAGGAATATTTCAAATGACAACAAATTCTGTGAATGGTAGTGCCGGAGCAACAGGAACGAAATTTTATAGTGCACTTCAAGTTGATACAAACTCTGTAAAACATCCATCTTTAATTTATGGATTGGGTCAAAGATATTTCGATGCTGGTAAATCTTTATTAGATACTATGTACAATTATCAACAAGAAAAATCAGCAGCAGCAGCTGCTGCTGCAGCTGAATCGGCTGGTCGAAACTACTTTGTCAGTCCTAGAAGTGGTACAGGACttgagaataataataataacagtaacaataataatataaaagaatctGTAAAACGGTCAcatactgaaaataataaaattacggagagaaatttacaaaatggtTTTAGCTGTGGAATATGTGAACGAAATGATTTCCGAACGGAAACCGAAGTACATTCACATCGAAAAATcgttcataatttaaaaactggTGTTAGTACACAATGTGCTTATTGTAGTGGTAATTTTAAATCACGCAGTGAACTAGAACACCATATGAAAACTAGTCATAATTCGACTGGTAAacataaatgtttaatttgtGATGAAATATTTCTATCACCGACGAATTTAGCTGAACACAAATTGCAAAAACATCCAATAGTTGGACAATCTGGAAAATGTTCACACTGTTCAATAGCTTTAAATGATGTATCGGCTTTTAAAAACCATTTATCTGAACACAATACTGAAGGGCAAATTCAATGTATTTGTTGCCGTCAAACTTTAAATTCAGATTTTGAAATTGGTTTACATGCAAAaTTCCATACGAAATCATCAGGAGCACCAGAAAATGCTTGTGCTCTTTGTTTAGAAGCACTTCCTAGCACTTCTGACACAAAAGTATGTGAGAAATGTTGCCGGAAacataatttaacaacaaaatttactaatatgCGTTTCGATAATCATTCGCacaaatcaaataattcatttatagaGAACCGATGTAATCTCTGTAAAATGATCCTGCCACATGCCCAACGACTACAAGAACATTTAGTAGAACATACTTTTGTTGGTTGTGAAGAACGTGGTTATTCTTGTTATATTTGTTCATCTGTTTTTACAATTCCTGCTGGGCTATTGGCACATATGTCATCAGAACATGGTCAAAATGCTCGGCCATATGATTGTAATTTATGTACAGAGAAATTCTTTTTCCGTGCCGAATTAGATAATCATTTAATTGAACATGAAAATAAAGGATCAGCAGTAGTAGTTCATTTGGAACATCAGAAACATGAAAATCGTGAAAAATGTAACGCCACATCATTGCCAAAAGACGAAAAGCCTAAGGAAATTGTATTAGGACAAGAAGCAGTAGAATTAAAAGCTGAGATTAAAATGGAAACAGTTGAAGAGCCTGAAAATGATGAAGAAGAATATATTGAAGTAGAAAAAGTAGTAGAACCTGTGGAAAATGATAGTGAAAAAAATGAATAG
- Protein Sequence
- MALKMLYRGPSSRLETLIEKIQATKEVNTDLYSTHTSSSYSPSMSEGAATPNSLLHHSQHLLYPTVNNLEVGENDDDNNRLRSNNNNNNHNLTNNKNFRRRRQLCRNSSTGNEVGVDDINEDEYEVDGSNNGADNENHEENDDGINSGNERVNNDSNIKEPIGKNDKKNIINRNSENVVNRKGTTKLRKIDRGESTGNKSTSNSGKITGNGIDDTGTIKNGTTTSDGSYQCQFCDKSFPRLGYLKKHEQSHAEHLPFKCDYCARLFKHKRSRDRHTKLHTGDRRYRCPHCEAAFSRSDHLKIHMKTHDNQKPFQCTVCNRGYNTAAALTSHMQNHKKQAALLGTGLQPLNYSPRSTGSGSSNGSYNTKRRYATVPLAVVAATTTAAGVDSNNSPTNHIGGGGGGDYNKRQRSTFISCVYCTKSDFTTLDQLNIHIQAMHENVLSTKINKDSPKHQHSLTIPNFQLNCEYCTMKFPNIPTMFQHMRATHIDRMSSPNSYFENFNRLAASGTFSPRLLTATPKNRFDDNGGGGSLKIKREEISPNNLIMDKNDNLVSEKDEEQIGPTDLSQPKKRVQTPFDRNTPTPSTGPISAELLEKHHQQQQQVGAGAFLCNQCNAALPDFETFRNHLKSHIQGINLVCQHCGLTLRDQNEYERHTISHFLITNTEFTCSSSCQKIYSKTEDLQKHLYEAHVQIMYKCSLCSDLFDTKVAIQVHFACAHSNETKIFRCSACMEQLRTEKDFTIHVKTRHQTGSGTIQCMFCRAVCSSELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQTHHNTGVNNQKDCHPPSDSPALAVNGPNQLFLNAAAQYAKQQQHNNNNNILDYHAFAASAAVAAGKGIFQMTTNSVNGSAGATGTKFYSALQVDTNSVKHPSLIYGLGQRYFDAGKSLLDTMYNYQQEKSAAAAAAAAESAGRNYFVSPRSGTGLENNNNNSNNNNIKESVKRSHTENNKITERNLQNGFSCGICERNDFRTETEVHSHRKIVHNLKTGVSTQCAYCSGNFKSRSELEHHMKTSHNSTGKHKCLICDEIFLSPTNLAEHKLQKHPIVGQSGKCSHCSIALNDVSAFKNHLSEHNTEGQIQCICCRQTLNSDFEIGLHAKFHTKSSGAPENACALCLEALPSTSDTKVCEKCCRKHNLTTKFTNMRFDNHSHKSNNSFIENRCNLCKMILPHAQRLQEHLVEHTFVGCEERGYSCYICSSVFTIPAGLLAHMSSEHGQNARPYDCNLCTEKFFFRAELDNHLIEHENKGSAVVVHLEHQKHENREKCNATSLPKDEKPKEIVLGQEAVELKAEIKMETVEEPENDEEEYIEVEKVVEPVENDSEKNE
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00643518;
- 90% Identity
- -
- 80% Identity
- -