Este020439.1
Basic Information
- Insect
- Empis stercorea
- Gene Symbol
- L
- Assembly
- GCA_949752835.1
- Location
- OX457088.1:426234-438910[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 17 7.1e-06 0.00071 20.7 1.7 1 23 220 242 220 242 0.98 2 17 0.59 59 5.2 5.8 1 23 248 270 248 270 0.98 3 17 3.1e-07 3.1e-05 25.0 3.1 1 23 276 298 276 298 0.99 4 17 2.5e-05 0.0026 18.9 0.2 1 23 304 326 304 326 0.98 5 17 0.34 34 6.0 0.2 2 23 400 423 399 423 0.88 6 17 0.029 2.9 9.3 0.3 2 23 451 473 450 473 0.94 7 17 0.1 11 7.6 0.4 1 23 589 611 589 611 0.95 8 17 0.0015 0.15 13.3 2.2 2 23 619 640 618 640 0.96 9 17 0.012 1.2 10.5 1.3 1 23 648 672 648 672 0.90 10 17 3 3.1e+02 2.9 0.9 1 23 707 730 707 730 0.96 11 17 0.0018 0.19 13.1 2.9 1 23 763 785 763 786 0.96 12 17 8.9 8.9e+02 1.5 0.2 1 23 971 995 971 995 0.83 13 17 0.0013 0.13 13.5 4.6 2 23 1004 1026 1003 1026 0.96 14 17 0.15 16 7.0 0.1 1 23 1032 1054 1032 1054 0.92 15 17 3.7 3.7e+02 2.7 0.5 2 23 1176 1197 1176 1197 0.93 16 17 0.0072 0.72 11.2 0.0 1 23 1207 1230 1207 1230 0.97 17 17 1.3 1.4e+02 4.1 0.8 1 23 1237 1259 1237 1259 0.93
Sequence Information
- Coding Sequence
- ATGGCACTAAAAATGTTATATCGTGGTCCTAGTTCAAGATTGGAaacattaattgaaaaaattcaagCAACTAAAGAAATCAATACTGatttatATTCAACTCATACATCATCAACATATTCACCATCAATGTCGGAGGGAGCAGCGACACCCAACTCCTTATTACATCATTCACATTTATTACAACCAAGAACAACTTTGCATAACACAGAAGATAATGAAGATGGTAATAATCGTCTTACGAGTACCAAcactaacaataataataatcatcttACAAATAATAAGAATCTTCGTAGACGACGTCAACATTGTCGAAATAGTTCAACCGCAAATGAAGGTGACATTAATGAGGATGAATATGAAATGGATGGCGGTGATGGTTGTTGTGTTGGTGCTGAAAATGGAATAAATGAAGGAGATGTTGGTTTTGATTCAGTTAATGAAATAATTGACGATGGTATTAATcttaaggaaaatttaaaaaatcatgataaaagaattataaatagaaatattagtGGAAGTGgtaatagaaaaattacaacaaaattgcGTAAAATTGATAAAGAATCAACAGCTAATAATAAATCTGAGTCGTTAAGAAATAGTATTGAGGGTGGTAGTACAATCAAAAATGGTACACCAGATGGTTCTTATCAGTGTCAGTTTTGTGATAAATCATTTCCACGTCTTGGTTATTTAAAGAAACATGAACAGAGTCATGCTGAACATTTACCATTTAAATGTGATTATTGTGCACGTTTGTTTAAGCATAAACGATCCAGAGATCGTCATACTAAATTGCATACAGGAGATCGTCGTTATCGTTGTCCACATTGTGAAGCAGCATTCTCAAGAagtgatcatttgaaaattcataTGAAAACTCATGATAACCAAAAGCCATTTCAATGTACTGTATGTAATCGTGGTTATAATACTGCAGCAGCTTTAACATCACATATGCAAAATCATAAAAAGCAAGCGGCACTTTTGGGTACTGGATTACAACCATTAAATTACAGTCCGCGATCCACGGGCTCTGGTTCAAGTAATGGTAGTTACAATACCAAACGTAGATATGCTACTGTTCCACTTGCAACACAAGCAGCAACAGCCGGTGGAGGTAATAATAATAGTCCATCAAATCATATTTCTGGTGATTATAATAAAAGACAACGTCCAACTTTTATATCTTGTGTGTATTGTACAAAATCAGATTTTGCAACATTGGATCAATTAAACATTCATATTCAGAAAATGCATGAAAATGTGTTAATAAAAACTAATCAGAAAGATTCACCAAAACATCAGAGCTCGTCGGTGACTATaccaaattttcaattaaattgtgAATATTGTACAAtgaaatttccaaatattccaAAAATGTTTCAACATATGCGGGCCATTCACATAGAACGTTTGTCTAGTCcaaattcatattttgaaaatttcaatcgTTTAGCTGCTTCTGGAACATTTAGTCCAAGATTAGTAACCGGAACAGCAACACTAAAAAATCGTTTTGATGATAATATTTCTGGTGTGAAAATTAAACGAGAAGAGAGAAGTCCAAATCATTTAATGGAGAAGAATGATAATTTAGTAAATGAGAAAGCTGAGGAGCAAATTGGTCCAACTGATTTGAGTCAACCGAAAAAGCGTGCACAAACTCCTTTTGAAAGGAGAACACCAACTGGTGGACCGCCAACAGATTTATTAGAAAAAGATCATCAGCAGCAGCAAAGTGCAGGTGCATTTCTGTGTAACCAATGTAATGCTGCGCTACCAGATTTCGAAACATTTCGTAATCATTTGAAAAGTCATATTGCACAAGGTATGAATTTAGTATGTCATCATTGTGGATTGACATTGCGAGATCAAAATGAATATGAACGACATACAATTtcacattttcttattacaaatTCCGAATTTTCCTGTTCAAATAGCTGTCAAAAAAGTTATTCAAAAACTGAAGATCTACAAAAGCATTTATATGATGCACATGTTCAAATTATGTACAAATGCTCATTATGTTCGGATTTATTTGATACAAAAGTTGCTATACAAGTGCATTTCGCCTGTGTACATTCCAATGAAACGAAAATATATCGTTGTTCTGCTTGTATGGAACAATTACGGACAGAAAAAGAATTTACTATTCATGTCAAAACTAGACATCAAACTAGTAGTGGTTCAATACAATGTATGTTTTGTCGTGCTGTTTGTTCATCCGAATTAGAAATGCATTTCCATTTAGCTGCACATGCTAGACAATTTCGTTGTCCATCATGTCCGGAAACTTTTCATGTTGAATTTCTACTTGATCGTCATATGCAAACACATCACAGTACTGCAGTGAATAATCAAAAAGATTGTAATCCGCCACCAGCAAGTCCTGTGTTAGTAAATGGTCCAAATCAACTTTTCTTAAATGCTGCTGCACAATATgctaaacaacaaaataataataataataatattttggagTATCATGCTTTTGCAGCATCAGCAGCAGCAGCTGCAGGTAAAGGAATATTTAAGATGACAAATTCTATGAACGGTTCAGTAGGAGCAGCAGGACAGAAATTTTATAGTCCACTTCAAGTTGATACGAATTCTGTAAAACATCCAGCTTTGATATATGGATTAGGTCAGAGATATTTTGATGCTGGTAAATCTTTATTAGATACTATGTATAATTATCAACAGGAAAAATCTGCAGCAGCAGCTGCTGCTGCAGTCGAATCAGCTGGTCGAAGTTTTTTTGTCAGTCCTAGAAATGGAACAGGACttgagaataataataattctattagtaataataacaatataaaaGAGTCTACAAAACGAACAcattctgaaaataataaaagttcagAAAGAAATATGCAAAACGGTTTTAGTTGCGGAATATGTGAACGAAATGATTTTAGAACAGAAATCGAGGTCCAATCACATCGCAAAATTGTTCATAATTTGAAAACTGGTGTGAGTTTACGATGTGCTTATTGTAGTGGTAATTTTAAGTCACGCAGTGAGTTGGAACATCATATGAAAACATGCCATAATTCAACGGGTAAACATAAATGTTTAATTTGTGATGAAATATTTCCATCGCCAGCAATTTTAGCTGAACACAAATTACAACATTCAAAAGTTGGACAATCTGGAAAATGTTCACATTGTTCGGTTGCTTTAAATGATGTGTTAGCATTTAAAGGTCATTTATCGGAGCATAATGTGGAGGGTCAAATTCCAGTACAATGTATTTGTTGTCGCCAAACTCTGAACTCTGATTTCGAAATAGGTTTACATGCCAAATTCCATACAAAATCTTCAGGAGCACCAGAAAATGCTTGTGCTCTTTGTTTAGAAGCTATTCCTGTAACTTCTGAAGCAAAAGTTTGTGATAAATGTTGCCGAAAACATAATTTGTCAACTAAATTCACCAATATGCGTTTCGACAACCATTCACaagacaaaaataataataataatttatttgtagaaaatcgatgtaatttatgtaaaatgatTTTGCCTCATGCCCAAAGACTGCAAGAACATTTGGTAGAACATACTTTTGTTGGATGCGAGGAACGTGGTTATTCATGTTATATTTGTTCAGCTGTTTTTACAATTCCTGCTGGGCTATTGAGCCATATGTCATCTGAGCATGGTCAAAACGCCCGTCCTTATGATTGTAATATATGTACGGATAAATTCTTTTTCCGTGCCGAATTAGATAATCATTTCATGGAACATGAAAATAAGGGACCTTCAGTAGTAAGTCTTTTAGAACAGAAATTTGTAGAAAATCCTCAACAACATGACATCATTTCAATGCCAAAAGATGATAAACCGAAATATGTGATGGTAAATGACGTGGAAGAAGAATTAAAAGCTGAAGTCAAAATGGAAACAATTGATGAGgctgataataatgatgaagaGGAAGAATATATTGAAGTAGAAAAAGTAGCTGAAACTGTGGATAATGTTACCAACGATAATGATTAG
- Protein Sequence
- MALKMLYRGPSSRLETLIEKIQATKEINTDLYSTHTSSTYSPSMSEGAATPNSLLHHSHLLQPRTTLHNTEDNEDGNNRLTSTNTNNNNNHLTNNKNLRRRRQHCRNSSTANEGDINEDEYEMDGGDGCCVGAENGINEGDVGFDSVNEIIDDGINLKENLKNHDKRIINRNISGSGNRKITTKLRKIDKESTANNKSESLRNSIEGGSTIKNGTPDGSYQCQFCDKSFPRLGYLKKHEQSHAEHLPFKCDYCARLFKHKRSRDRHTKLHTGDRRYRCPHCEAAFSRSDHLKIHMKTHDNQKPFQCTVCNRGYNTAAALTSHMQNHKKQAALLGTGLQPLNYSPRSTGSGSSNGSYNTKRRYATVPLATQAATAGGGNNNSPSNHISGDYNKRQRPTFISCVYCTKSDFATLDQLNIHIQKMHENVLIKTNQKDSPKHQSSSVTIPNFQLNCEYCTMKFPNIPKMFQHMRAIHIERLSSPNSYFENFNRLAASGTFSPRLVTGTATLKNRFDDNISGVKIKREERSPNHLMEKNDNLVNEKAEEQIGPTDLSQPKKRAQTPFERRTPTGGPPTDLLEKDHQQQQSAGAFLCNQCNAALPDFETFRNHLKSHIAQGMNLVCHHCGLTLRDQNEYERHTISHFLITNSEFSCSNSCQKSYSKTEDLQKHLYDAHVQIMYKCSLCSDLFDTKVAIQVHFACVHSNETKIYRCSACMEQLRTEKEFTIHVKTRHQTSSGSIQCMFCRAVCSSELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQTHHSTAVNNQKDCNPPPASPVLVNGPNQLFLNAAAQYAKQQNNNNNNILEYHAFAASAAAAAGKGIFKMTNSMNGSVGAAGQKFYSPLQVDTNSVKHPALIYGLGQRYFDAGKSLLDTMYNYQQEKSAAAAAAAVESAGRSFFVSPRNGTGLENNNNSISNNNNIKESTKRTHSENNKSSERNMQNGFSCGICERNDFRTEIEVQSHRKIVHNLKTGVSLRCAYCSGNFKSRSELEHHMKTCHNSTGKHKCLICDEIFPSPAILAEHKLQHSKVGQSGKCSHCSVALNDVLAFKGHLSEHNVEGQIPVQCICCRQTLNSDFEIGLHAKFHTKSSGAPENACALCLEAIPVTSEAKVCDKCCRKHNLSTKFTNMRFDNHSQDKNNNNNLFVENRCNLCKMILPHAQRLQEHLVEHTFVGCEERGYSCYICSAVFTIPAGLLSHMSSEHGQNARPYDCNICTDKFFFRAELDNHFMEHENKGPSVVSLLEQKFVENPQQHDIISMPKDDKPKYVMVNDVEEELKAEVKMETIDEADNNDEEEEYIEVEKVAETVDNVTNDND
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00643518;
- 90% Identity
- -
- 80% Identity
- -