Dtri002151.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Dysmachus trigonus
Gene Symbol
egg
Assembly
GCA_949715965.1
Location
OX454319.1:25161498-25172347[+]

Transcription Factor Domain

TF Family
MBD
Domain
MBD domain
PFAM
PF01429
TF Group
Unclassified Structure
Description
The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 1.4e-14 8e-11 42.8 0.1 5 70 811 869 808 875 0.90

Sequence Information

Coding Sequence
ATGGATAATAAAACGGACCTTAGTATAGATGAGTTAAAGAAAGATCCCGAAGAAGCGGCGGCGGACAGCAAAGAAAGTCGGACTATGGAAGCTGCGGACGACTCCGCGACCAAGGAGACTTCAGAAGAAGTCATCGAACTCAACAGTTCAATTGATTCAGACACTCCCGAAAAGCAGCAACCGGACGAAAAATCAATTGCTGAAAAAGAATCTGAAGAATTGCAGGAGGAGAAAGAGGCCACTGCTGAAGTCAGTGGCGATGACATGGACGTCGATGAGACGCTTACAAATCGAGAGCCAGAAATTATACAACCGCCCAGGGAAGCCCCCGTTTTGGAAAGTCCAGAGGATCCGAAACCTAGCTGCTCACAAGAGGAAGCCGCTGACGATAAGGAGGAAGACGCAAAAGATATTACAGAACTAGCTGAAGATGAGGAGCCAGCTCTTATTCCGATTGGTGTTCGAGAAGACGACGAAGAATTGGAGCCCGAAGGACATGAGTCTCCGGAGGACCCAGCAACTCCTGTTGAGATTCTCGACGTAGAACCTGAAAAGGAAGCCGATGAGATCAGTGCGCGAGAATCTCCCgtggaaaaaatggaaattgaTTGCATTGAAGAGAATTTGAAGACCGAAGAAGATCTAGAAAATAAGGAAAACACTTTAGAATTAGATGTGATCCCCATGGAGATTTCTAAGcaagaggaaaataataaaaaatcatccGTTGAATGCACTGATATGGGCAAGATTATAAGCGAGAAAATAAGGCAAGTCATGGACGAGGAGGAGTTCATCTTCCACGGAAGGGAGTGCGTCAATTACGAGTGCGCTCAGAACAGTAAGATTTTTTACAAGGCTCCAATATttgctttgaatttttataaggCTTCACGGAAGTTGAACAAACTCCAATTTGTTTGTGATGAGTGCTACAACAAATCTATCAGCAAATATGAGgaaCTGACCGGAGCTCTCGTCACTCATCAACCGCTTTTGATGCAAAATATCACGAAGAGGCAAGAATTTGTGGAGATTTTGGACAGCAGCGATGAGGAGGATACTAAAGAGAAGGATGAAAAGGATGAAGAACCCGGAGACTTTCAAAGAGAAACTATTGATTTCCTCTCAGAAGAACTTGACGCAACTATTAGCAACATTTTAAAGCGTGTGCAAATAGAAAgtcaagtaaattggacaaaaaGCATTCttcagaagaaaattaaaaaattagaagAGGACTCTGATTTTATATCAGAAAGTCTAAAAAATCTACAAAAGAGCGCAGATACTATGCACAATTCGCTTTATCAATgccctaaaataaaaataagggagTTGATGCCGCTCGACTTAAATACAGGAAGGCTGTACTTGACTGAGAATGAGATGACGattCCACCAATCGGAGAACTGTCTTTTCCGCCAATTGAAATTAATGGCTCATATTTTGCTGTTAAAAACAATGTAATAGCCAGCTGGTTACCATGTAAAGCTGTTGAGTTTATAGATGCATCAGTTACTATGTCGAAAACGGTTAAATACTATAGAGTAAAATTTCATAAGATGAAAATCCCAACAATTAAGTGTGTACCTGCAAAACATATGGCTTATGGTGATCCTCCAAAAGTTCGGCTGCAAATAGgaacTCGAATTATTGCTCTTTTTGACGGTTCTACTCTTAgcagaaataaagaaaaaattcccaattttaAGAGTGCTTTTTACCCCGGAATTGTTGCTGAACCGCTACAGTCTTACAATAAATACAGatatttgatCTTCTTTGATGATGGGTACGCACAGTATGTTTGTCACAAAGATGTGCGTGTAGTGTGTCAAGTTTCAGAAAATGTTTGGGACGATGTACATCCGTCTTCAAGAGAATTTATTCATAACTACGTAACGCAGTATCAGAGGAATCGTCCGATGGTGCAGGTGAAGAAGGGTCAAAGCATGATAACTGAGTCTAATGGAAAATGGCTCTACGCTAAAGCTATAGACATTGATGCGAGCTTAGTGCAGATGCTCTTCGATGGACAAAATCGTACAGAATGGATTTATAGAGGATCTACTAGACTTGGTCCACTATTCAGGGAGAAGCAAACAAAACGGTCTATGCTAGTATCACAATTACCTAGGCGAAGTGAACCTTATGTTCGTTACTGGGAGGATGAAGAAGCTACTAAGAACGATAGCAACGCTGAGAAGCAGAATCGTGCAGTTGCAAAGAAGAGTACCACTTCGAAGAATGATTATCAGCAACCTATAAAACACTTGAATAATTCCACGATATTTCTCGATGATAACAAGCCTAAAGGAAAGGTGGTCTATTACACAGCAAAAAAGAATATGCCGCCTAGGCCGTATAATCCTCACGAATGCAGTCCCAGATGCTTATTTAATATTTCGCATAATTTGAGCAGTTACAGTCCATTGGCAAAACCCTTACTTTCTGGCTGGGAACGTCAAATATTTAAGAGTAAATTGAAGAAATTTGTCGTTTATCGAACTCCATGTGGCCGTCGTGTAAGAAATATGGAGGAGTTGCATAAATATTTAAGGAAAACGAAAAATAACTTGAATGTTGACAACTTTGACTTTGATATTCTCATTCATTGTCTGGCGGAGTTTGTTATCGAGAGTAGTATTGTTCAGAAACATGACCTCTCAGAGGGAAAAGAAAACATGATAATTCCGTGCATTAACTACTACGATAATACAATGCCTCCCGAATGCACTTATTCTACTAAACGAATACCAACTGAGGGCGTTAATTTGAACTTAGATCCAGAATTTTTAACTGGATGTGATTGCGAAGATGATTGTcttGACAAATCGAAATGCAGTTGCTGGCAGCTAACTATCCAAGGAGCTCGATTTGGTAATCCAAATACACCGTCAGAAAGTGTTGGATACCAATATAAAAGATTACCTGAAGCAGTTCCCACCGGCATTTATGAATGTAACGTTAAatGTAAGTGTTCAAAGAACTGTCTTAATCGTGTTGTGCAGCATCCACTTCAGATGAAGCTCCAAGTCTTTAAAACCTCTAATAGGGGCTGGGGACTTCGGTGTATTAATGATGTTCCAAAAGGTAGTTTCATCTGCATTTATGCGGGGCATTTACTTACTGAACAGAATGCAAATGAAGtgGGCGGCGCAAATTCTGGTGATGAATATTTTGCAGAATTGGATTATATTGAAGTTGTTGAAAGACTCAAAGAAGGATACGAATCTGATGTTCAAGAGGAAGTTGAAGAAAGTGAGGAAGAATTTGAGgAACCAGCTCAAGAAAACGATTCAGATGAAGACTTTCGATTAAATGTCCACGTCAACAAAAATCTTCCAATCAACACAAGATTAAGGTCTCGTCGTAGCACAAAAGAATATTCGAAGAAAAGtaatgatgatgacgaagaAGAGGAGCGCCAGGTTATTAATTTTGAGCCAAACACTTCTCTTGATAATGAGGAGAGTACGAATACTAAATATAGgTCGATCAGAAAATACTTTGGCAAAAATGAGTTTTGCTACGTTATGGATGCAAAGAAGACCGGTAATATTGGACGATATTTTAATCATTCCTGTTCACCAAACCTATTTGTCCAAAATGTTTTTGTCGACACACATGATCTTCGGTTCCCATGGGTAGCATTCTTTGCTCTGACCCATATCAGAGCAGGGACTGAATTGACTTGGAATTATAATTATGAAGTTGGTATTGTACCCGGAAAAGTTTTATTCTGCGAGTGCGGTGCTCCAAATTGTCGCGGGCgtttactataa
Protein Sequence
MDNKTDLSIDELKKDPEEAAADSKESRTMEAADDSATKETSEEVIELNSSIDSDTPEKQQPDEKSIAEKESEELQEEKEATAEVSGDDMDVDETLTNREPEIIQPPREAPVLESPEDPKPSCSQEEAADDKEEDAKDITELAEDEEPALIPIGVREDDEELEPEGHESPEDPATPVEILDVEPEKEADEISARESPVEKMEIDCIEENLKTEEDLENKENTLELDVIPMEISKQEENNKKSSVECTDMGKIISEKIRQVMDEEEFIFHGRECVNYECAQNSKIFYKAPIFALNFYKASRKLNKLQFVCDECYNKSISKYEELTGALVTHQPLLMQNITKRQEFVEILDSSDEEDTKEKDEKDEEPGDFQRETIDFLSEELDATISNILKRVQIESQVNWTKSILQKKIKKLEEDSDFISESLKNLQKSADTMHNSLYQCPKIKIRELMPLDLNTGRLYLTENEMTIPPIGELSFPPIEINGSYFAVKNNVIASWLPCKAVEFIDASVTMSKTVKYYRVKFHKMKIPTIKCVPAKHMAYGDPPKVRLQIGTRIIALFDGSTLSRNKEKIPNFKSAFYPGIVAEPLQSYNKYRYLIFFDDGYAQYVCHKDVRVVCQVSENVWDDVHPSSREFIHNYVTQYQRNRPMVQVKKGQSMITESNGKWLYAKAIDIDASLVQMLFDGQNRTEWIYRGSTRLGPLFREKQTKRSMLVSQLPRRSEPYVRYWEDEEATKNDSNAEKQNRAVAKKSTTSKNDYQQPIKHLNNSTIFLDDNKPKGKVVYYTAKKNMPPRPYNPHECSPRCLFNISHNLSSYSPLAKPLLSGWERQIFKSKLKKFVVYRTPCGRRVRNMEELHKYLRKTKNNLNVDNFDFDILIHCLAEFVIESSIVQKHDLSEGKENMIIPCINYYDNTMPPECTYSTKRIPTEGVNLNLDPEFLTGCDCEDDCLDKSKCSCWQLTIQGARFGNPNTPSESVGYQYKRLPEAVPTGIYECNVKCKCSKNCLNRVVQHPLQMKLQVFKTSNRGWGLRCINDVPKGSFICIYAGHLLTEQNANEVGGANSGDEYFAELDYIEVVERLKEGYESDVQEEVEESEEEFEEPAQENDSDEDFRLNVHVNKNLPINTRLRSRRSTKEYSKKSNDDDEEEERQVINFEPNTSLDNEESTNTKYRSIRKYFGKNEFCYVMDAKKTGNIGRYFNHSCSPNLFVQNVFVDTHDLRFPWVAFFALTHIRAGTELTWNYNYEVGIVPGKVLFCECGAPNCRGRLL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00936546; iTF_01183842; iTF_01049673; iTF_00717807; iTF_01461173; iTF_00937303;
90% Identity
-
80% Identity
-