Basic Information

Gene Symbol
-
Assembly
GCA_029618875.2
Location
JAROYD020000001.1:14323663-14334085[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 0.0005 0.058 15.5 1.6 1 23 165 187 165 187 0.99
2 16 0.00074 0.086 14.9 7.1 1 23 192 214 192 214 0.97
3 16 2.3e-05 0.0026 19.7 4.2 1 23 220 242 220 242 0.97
4 16 0.0074 0.87 11.8 1.7 3 20 250 267 248 268 0.94
5 16 4.1e-05 0.0047 18.9 0.3 1 23 276 298 276 298 0.97
6 16 0.0066 0.77 11.9 0.4 1 23 469 491 469 491 0.97
7 16 9e-06 0.001 21.0 1.8 1 23 496 518 496 518 0.98
8 16 9.5e-06 0.0011 20.9 8.4 1 23 524 546 524 546 0.98
9 16 0.00011 0.013 17.5 0.9 1 23 552 575 552 575 0.95
10 16 0.00027 0.032 16.3 1.3 1 23 582 604 582 604 0.98
11 16 8.8e-05 0.01 17.8 5.9 1 23 610 632 610 632 0.97
12 16 2.7e-06 0.00031 22.6 0.5 1 23 639 661 639 661 0.96
13 16 1.9e-05 0.0023 19.9 1.3 1 23 667 689 667 689 0.98
14 16 2e-06 0.00023 23.0 0.5 3 23 697 717 695 717 0.96
15 16 6.2e-05 0.0072 18.3 0.3 1 23 723 745 723 745 0.99
16 16 0.018 2.1 10.6 0.4 1 23 750 773 750 773 0.96

Sequence Information

Coding Sequence
ATGGAGTCTATACAATTAGACCTCAACAATGTGTGCAGAACCTGCAAAAATGAGTCGCCAGAAATGAAGTCGTTGTATTATAGAGACTCGGAAAGTGGCAAAGAAAACCCCCGTTTAGACGAGATGCTAATGGCATGTGCTTCCGTTCAGGTTAACAACGACGACGGATTACCAAAATTGATATGTCGATCGTGTTTTGTGCAGTTAAAGAATGCATATTCCTTCAAGGAACAATGCGAAAAGACGGATATATTTTTCAGAGATTACGTGAAAACTTTACAAAAGGGAAATATAAAGGAGGAAAATGCTATAACAGAGTTGGAATTTTCAGCAAATTTGATGAACGAACTTGATGCTACTTTAGATGACGACAGCTGTAATAGAAGTGAAGATATCATAGATAATATCAAAGACGATCCAGAAAATAATTCAGGAGAGGTATCCGAAAAAAATCTGGATTATATTCAGGTAGTTGATAGTGATATAACAGTTTACGAATGTACAACATGTTCAAACGTCTTTTATACTTTGGAAGATTTAAAAAGCCATAAGAGATCACATACTCGTAGAATCTTCAAATGCAAGCAATGCGATAGATCCTATACAAGATTGAATCATCTCCATAGACACGAATCATCTCATGGCAAGCGGAAAATGCACGTCTGTAAGATATGCAATAAAACGCTTACCAGGCTCGAACATTTGAAGCGTCATCTGATAACACATTTGAAAGAAAAGCCTTATGGCTGCCCACGTTGTAACCGTGGTTTTAACCGTTTCGAACATCTTCGTCACCATGTCAATTGTTGCAAAGGGGAAAAggtgtatatatgtaatatttgcAATAAAGCCTTTAATCGAGAAGATAGTATGGAAGTACATAGGCAGTTACATGAAAATAAGGAACCTGTTCTACCAACTTTAGATAATTTAGATAACATAGCAGAGCACTATATGGAAATAGAGTTCGATGAAAAAGCTGACGTATTTTCTGAGCAATCCGAAGAAGAAGACATGAATGTAAGTGAAGAAACGATGGAGCCAGAAGTTGAGGTTTCAGAGAACAATGACCAAGAGAAAATAGACGAAATAGCACATATAACTAGCGATATTTATGAAAAGGAAGATCCTTCTGATTTGCTACTAGAGAAATCAAGAATTCAGGAAGAAATACTTGGGGATGACGAAGATGGACTTTTGGATATTGGTAATGGAAATGATTATCAATCTGATAATAGTGTCAATTCCGAATATTTACCAATGAAACCGTCACCACCAAAAATCAAACGTGGTAGAGGAAGACCTCGCAAATATCCTGTAGCTTACAGGTCTACCGGCAGGCCAAGAGGACGTCCTCCTCTCAATCACAATCTTAAAACTGAAGCGGGCTCGGAAACTGGCCATTTTGTATGTCCAGAGTGTAAGCAACTCTTCACCAAGGTGAATCTATTCGAGAGGCACGTCCAAgagcatggtttgaagatgtaCGAATGTGATACATGCCCTAAGACATTTAGTAGGATGAATAGTCTTAAGAGACATAAATTATCGCATGGGAAAGTGAAGCCGTTCTCGTGCTCGTCGTGTAAAAAATGCTTCTCAAGGCGCGATCACTTGCAGAAGCATATGAGATTGCACCTCAGCTCTGAATCCTTTACATGTGATATATGTCAGATGACATTCAGTAAAGAAGAGAGTTTACAAAAGCACAAAGCTGTTAAACATTGCATTGGCGAGAAGAAATTCAAATGCGAATATTGTCCGAAGGCTTTCACAACCGAAAAATATCGCGATTCCCATATGAAGGCCCATCTGGGTGAGAATACATTCCAGTGTAGGacctgtaataaaacatttatatcGAAATCTCATTTAACCGAGCACACGAAGTTTCATAATGATAGTTCGAAGAAATTTTTGTGTTCCGAGTGTGGACAGAGATTTATTAGGAATGACTATTTGGTGGTTCATATGAGGCGGCATCGCGGCGAGAAACCATTCAAGTGCAAATTCTGTGGTAAAGGTTTTCCTCGAACGACAGATTTGACAGTACATGAGAGGTATCATACTGGTGAAAAGACGCACTTATGTGTTATCTGTGGAAGAGGTTTTGGAAGgGCTTATAACTTGACAGTTCATATGAGAACTCACACCGGAGAGAAACCTTATCGTTGCACATATTGCGATGCAGCCTTTGCCCAGGGTAACGATTTGAAGTCACACGTTCGAAGACATACAGGCGAAAGATTCCAATGTGAATTGTGTCCAAAAACGTTCTTAATGGGATATTTATTAACTCAACACAAAAGGGTTGTTCacgGTTTAAATATTGTTAGCAACATAAGGCGATTGCAACCAGTTACGAAATTAAACCCGGATGACCCTCTCCCGATCACAGTACCACTGCCTGCACCTGTGGTAGTAACAACACCTGTCATTAAAGTGGATCCGCTGCAAATAAAGCAGGACGATTTGCCTGAACTAAAACAAGAGTAG
Protein Sequence
MESIQLDLNNVCRTCKNESPEMKSLYYRDSESGKENPRLDEMLMACASVQVNNDDGLPKLICRSCFVQLKNAYSFKEQCEKTDIFFRDYVKTLQKGNIKEENAITELEFSANLMNELDATLDDDSCNRSEDIIDNIKDDPENNSGEVSEKNLDYIQVVDSDITVYECTTCSNVFYTLEDLKSHKRSHTRRIFKCKQCDRSYTRLNHLHRHESSHGKRKMHVCKICNKTLTRLEHLKRHLITHLKEKPYGCPRCNRGFNRFEHLRHHVNCCKGEKVYICNICNKAFNREDSMEVHRQLHENKEPVLPTLDNLDNIAEHYMEIEFDEKADVFSEQSEEEDMNVSEETMEPEVEVSENNDQEKIDEIAHITSDIYEKEDPSDLLLEKSRIQEEILGDDEDGLLDIGNGNDYQSDNSVNSEYLPMKPSPPKIKRGRGRPRKYPVAYRSTGRPRGRPPLNHNLKTEAGSETGHFVCPECKQLFTKVNLFERHVQEHGLKMYECDTCPKTFSRMNSLKRHKLSHGKVKPFSCSSCKKCFSRRDHLQKHMRLHLSSESFTCDICQMTFSKEESLQKHKAVKHCIGEKKFKCEYCPKAFTTEKYRDSHMKAHLGENTFQCRTCNKTFISKSHLTEHTKFHNDSSKKFLCSECGQRFIRNDYLVVHMRRHRGEKPFKCKFCGKGFPRTTDLTVHERYHTGEKTHLCVICGRGFGRAYNLTVHMRTHTGEKPYRCTYCDAAFAQGNDLKSHVRRHTGERFQCELCPKTFLMGYLLTQHKRVVHGLNIVSNIRRLQPVTKLNPDDPLPITVPLPAPVVVTTPVIKVDPLQIKQDDLPELKQE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

90% Identity
iTF_00956465;
80% Identity
-