Druf002065.3


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drymonia ruficornis
Gene Symbol
-
Assembly
GCA_947859195.1
Location
OX401920.1:5691412-5703801[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 18 8.9e-05 0.0054 17.2 0.1 3 23 131 151 130 151 0.97
2 18 8.1e-07 4.9e-05 23.6 1.2 1 23 157 179 157 179 0.99
3 18 5e-06 0.0003 21.1 2.7 1 23 185 207 185 207 0.99
4 18 2.2e-06 0.00013 22.3 2.3 1 23 222 244 222 244 0.99
5 18 0.00014 0.0087 16.5 0.6 1 23 259 281 259 281 0.98
6 18 4.6e-05 0.0028 18.1 3.1 1 23 296 318 296 318 0.98
7 18 3.2e-07 1.9e-05 24.9 1.5 1 23 333 355 333 355 0.99
8 18 0.00014 0.0085 16.6 2.8 1 23 361 383 361 383 0.98
9 18 1e-05 0.0006 20.2 2.1 1 23 389 411 389 411 0.99
10 18 0.033 2 9.1 1.8 1 23 418 440 418 440 0.98
11 18 3.1e-06 0.00018 21.8 2.5 1 23 446 468 446 468 0.99
12 18 0.038 2.3 8.9 1.8 1 23 475 497 475 497 0.98
13 18 2.2e-06 0.00013 22.2 1.5 1 23 503 525 503 525 0.99
14 18 0.00014 0.0086 16.5 1.0 1 23 532 554 532 554 0.99
15 18 2.4e-06 0.00015 22.1 1.9 1 23 560 582 560 582 0.98
16 18 0.0018 0.11 13.1 0.3 1 20 588 607 588 610 0.93
17 18 3.5e-05 0.0021 18.5 1.4 2 23 617 638 616 638 0.96
18 18 2.7e-06 0.00016 22.0 1.3 1 23 644 667 644 667 0.97

Sequence Information

Coding Sequence
ATGTTCGAACAGCAGATCAAAGCGGAACCCATGGGTTTCTACACACCCCATCCGCACATACACTCCGGCCCCCCAACGATAGTCCGGTCAGATTCAAGCCATCCCATCATCAACATGAACCAACACCATCACCAAGAGGACTCTAAAGACAGCCTCATACAACAACAAGTACAGCATCAGCAAGATCTCATGGAACAACATCAACAACAACAGGAAATGCAACAACAAGACGATGAGCTAAGTTTCAAAGGCATGGAAGATGAAGGTGTTGAAATGGATATGGACGGACGGCAATGTTCTCAGGGTATGGGCGTGGACATGGGATCAGTTCCAACAAAAATGGAAGTATCAAACGGTGGGCAGTCAGCACCGCGGTCTAAACCACAGGCCTGTAAGGTCTGCGGTAAAGTGCTTTCCTCGGCTTCGTCATATTATGTCCATATGAAGTTGCACTCCGGAAACAAGCCCTTCCAGTGCACTGTTTGCGACgcagcgttttgccgcaagccgtacctggaggtgcacatgcgcacgcacaccggcgagcggcctttccagtgcgacctgtgtctcaagcgcttcacgcagaagtccagcctcaacacgcacaaacgcgttcacacagatgagcacatgcgcgcgttgatggtgaaggaccggccctacaggtgcgagctctgtcagatgcggttcacgcagagctccagcctcaaccgccacaggaaaattcacacggAGGAACACAGACGCGCGCTGCTGGCTAAGGAACGCCCCTACCAATGCGGCGTCTGCTTTGTGCGATTCACCCAGAAATCGAGTTTGGGCCGGCACGGAAAAATTCATACCGAGGAGCACAGACGAGCCCTGTTAGAGAAAGTgcggccgtaccagtgccacatctgttttatgcgcttcactcagaagtccagcctgggacgacatgGGAAAATACACACTGAGGAGCACATCCAATCGCTGATCAACAAAGTgcgcccctatcaatgcgacatctgtgacaagcggttcactcagaagtccagccttggcactcataaacgtatacacactggggagcggccgttccagtgcaccgtctgcctcaagtccttcacgcagaagtgcgcgctcaatttgcacgaaaaaatccatacgggcgagcggccctatcagtgcgacgcgtgtctgaagcgcttcacgcagaagtccagcctcaatatacataaacggacgcacacagtccagggcagaccgttccagtgcctgtcgtgcccggcggcgttcacctgcaagcaatacctggagatacacacgcgcacccacaccggcgagcgaccgtatcaatgcgacatctgcatgaagcgcttcacacagaaatccagtctcaacatacacaagcggacgcactcagtgcagggccggcccttccagtgcctgcagtgccccgccgccttcacctgcaagcagtacctggagatccacaaccgcacgcacacgggcgagcgcccctaccagtgcgacgtctgcctcaagagattcgcgcaaaagtccacactcaacatacacaaaagaacgcacacagtgcaagggcggccgtaccgctgcacggagtgtccggcggcgttcacttgcaagccgtacctggagattcacatgcgcacgcacaccggcgaacggccgttcgagtgcgatgtttgttacaaacgcttcacgcagaaatccacgctcaacattcacaagcgaattcataccgGTGAACGACCTTATGCTTGTGATATTTGCCAGAAACGATTCGCTGTAAAGAGCTATGTAACGGCACACAGATGGTCTCACGTGGCGGACAAGCCGCTGAACTGCGACCGCTGCTCGATGACGTTCACCTCCAAGTCGCAGTTCGCGCTGCACATCCGCACGCACTCGGCCACCTCCTGCTACGAGTGCAGCGTCTGCGGACGGTCCTTCGTCAGGGACAGCTACTTAATAAGACACCACAACCGCGTGCACCGCGAGAACCACAGCAACATGTCGGCCAACAGCCTCGGCACCATCAACAGCGTCGCCACCAACACCAACAACTCCAACAGCAACTACGACTCCCCCGGCGTTTGTGACTTAAGCTTTGTACCGATGGTGAATCGTTACATGACATCCCAGGGTACACAGGTGTCCATGCAAGACACACAGAGCAAGATGTCAGCGATGTCGCCGCAATCAATCGCGTCTATTTCGTCGCCCCCTCCATCGCACACGCCGACGCCCCAACCGCAGTTGTCTGGTCAGATGCACCTTGCAGACTGA
Protein Sequence
MFEQQIKAEPMGFYTPHPHIHSGPPTIVRSDSSHPIINMNQHHHQEDSKDSLIQQQVQHQQDLMEQHQQQQEMQQQDDELSFKGMEDEGVEMDMDGRQCSQGMGVDMGSVPTKMEVSNGGQSAPRSKPQACKVCGKVLSSASSYYVHMKLHSGNKPFQCTVCDAAFCRKPYLEVHMRTHTGERPFQCDLCLKRFTQKSSLNTHKRVHTDEHMRALMVKDRPYRCELCQMRFTQSSSLNRHRKIHTEEHRRALLAKERPYQCGVCFVRFTQKSSLGRHGKIHTEEHRRALLEKVRPYQCHICFMRFTQKSSLGRHGKIHTEEHIQSLINKVRPYQCDICDKRFTQKSSLGTHKRIHTGERPFQCTVCLKSFTQKCALNLHEKIHTGERPYQCDACLKRFTQKSSLNIHKRTHTVQGRPFQCLSCPAAFTCKQYLEIHTRTHTGERPYQCDICMKRFTQKSSLNIHKRTHSVQGRPFQCLQCPAAFTCKQYLEIHNRTHTGERPYQCDVCLKRFAQKSTLNIHKRTHTVQGRPYRCTECPAAFTCKPYLEIHMRTHTGERPFECDVCYKRFTQKSTLNIHKRIHTGERPYACDICQKRFAVKSYVTAHRWSHVADKPLNCDRCSMTFTSKSQFALHIRTHSATSCYECSVCGRSFVRDSYLIRHHNRVHRENHSNMSANSLGTINSVATNTNNSNSNYDSPGVCDLSFVPMVNRYMTSQGTQVSMQDTQSKMSAMSPQSIASISSPPPSHTPTPQPQLSGQMHLAD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00010401;
90% Identity
iTF_01430114;
80% Identity
-