Dyoo008676.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila yooni
Gene Symbol
ftz-f1
Assembly
GCA_035043035.1
Location
JAWNNG010000419.1:3833321-3847097[-]

Transcription Factor Domain

TF Family
SF-like
Domain
zf-C4|SF-like
PFAM
AnimalTFDB
TF Group
Zinc-Coordinating Group
Description
The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 4 2 1.8e+04 -13.4 31.2 33 160 16 163 4 174 0.49
2 4 0.8 7.1e+03 -4.0 16.9 44 124 95 172 77 210 0.39
3 4 1.9e-19 1.7e-15 57.4 0.5 1 78 337 413 337 437 0.74
4 4 2.6e-72 2.3e-68 231.5 1.3 157 408 537 781 501 783 0.91

Sequence Information

Coding Sequence
ATGTTATTAGAAATGGATCAACAACAGGCGACTGTACAGTTTATATCGTCGCTGAATCTGTCGCCGTTTAGCATGCAACtcgaacaacagcagcccGCGAGTCCGGCGCACAGCAACACTAACAAcgctaacaacagcaacaacaacaacaacagtagcaacagcaacaacaacaacaacagcagcagtaatagcaacaacaacaacagtaacaatgaTAACGATACAAATGCATTGAGCAATTCCGATAACGATTACAGTGCATACACGCTGCAACTGGGgagtcatcagcagcagcagcagcaacacccacATCATAcacatcaccagcagcagcagcaacaacaacagcaacagcagcagcagcattaccaacagcaacaacaacagaatattgccaacaacaatgcgaatgcAGCGGCGAATCAATTCAATGCTTCCTCCTATtcgtatatatacaatttcgATTCACAGTACATATTCCCGACAGGCTATCAGGAAACGAACTCATCGCATTCGCAGCAAAGTGCAAATGGAGCCGGCAATgccgcagcagctggcaactcTGGCCAGCTCCTGaacggtggcagcagcagctcgacaGGTAATAGTTACATGCTGTTGCCACCGGGCGCTGGTGGcacctctgctgctgccgctgcccatATGTCCGGCAATGTGGGCGGCAATCCGGCCGCGGGCGTAAGTGGAACCGCTGCCGGCGGTGGTCATCATGGCGGCACCAGCGCCAGTTCTGGCGGCGGCGAAGCCATCGATTTTAAGCATCTGTTCGAGGAGCTGTGCCCCGTCTGCGGAGACAAGGTGAGCGGCTATCACTATGGCCTGCTCACCTGCGAGTCCTGCAAGGGCTTCTTCAAGCGCACcgttcaaaacaaaaaggtCTACACTTGTGTGGCGGAGCGCTCCTGCCACATCGACAAGACGCAGCGCAAACGTTGTCCATATTGTCGATTCCAGAAGTGCCTAGAGGTGGGCATGAAACTAGAGGCGGTTCGAGCGGACCGGATGCGTGGCGGTCGCAATAAATTTGGACCCATGTACAAACGGGATCGGGCGCGAAAGCTGCAAGTGATGCGTCAGCGGCAACTGGCGCTGCAGGCGTTGCGCAGTTCGATGGGCACGGACATAAAGCCGACGCCTCTCTCGCCGGGCTATCAGCAAGCATAtccaaatatgaatattaagcAAGAAATTCAAATACCTCAGgtATCCTCACTCACACAATCGCCAGACTCATCGCCCAGCCCCATTGCTATTGCCTTGGGTCAGGTGAATGCGAGCGGGGGCGGTGTGATAGCCACGCCGATCAATgccggcaatggcaatggtgGCTCCTCACTTGGCAATggcggcaatggcaacaacaacaccaacaacagcggcaCAGGCAGCGGaagcggaggaggaggaggaggggctGGTGGAGGAGGCAACAATactggtggcaacaacaacatcaccgATGGCCTGCAACGCAAtggaaacagcagcaatagcaacagcaacagcagttgccacGAAATCGGCACTGGATCTCTACAGAACTCAGCCGAAGCGAAATTGTGCTTCGATTCTGGCACACATCCATCGAGCACAGCCGACGCGCTTATTGAGCCACTCAGggTCTCACCAATGATACGCGAATTTGTGCAATCGATCGATGATCGGGAATGGCAAACGCAACTTTTTGCGCTACTGCAGAAGCAGACGTACAATCAAGTTGAAGTGGATCTCTTTGAGTTAATGTGTAAAGTGCTTGATCAGAATCTATTCTCACAAGTGGATTGGGCAAGAAACACCGTCTTCTTTAAGGATTTAAAGGTTGACGATCAGATGAAGCTGCTTCAGCATTCTTGGTCCGATATGCTCGTGCTGGATCATTTGCATCATCGCATTCACAACGGTCTGCCCGATGAGACTCAGCTGAATAACGGTCAGGTCTTCAATTTGATGAGTCTTGGTCTGCTGGGTGTGCCACAGCTGGGTGACTATTTCAACGAGCTGCAGAATAAGCTGCAGGAACTGAAGTTCGATATGGGCGACTATGTTTGCATGAAATTCCTAATACTGCTAAATCCAGATGTGCGAGGCATTGTTAACAAGAAGACCGTCTTGGAGGGACATGAGAATGTTCAGGCCGCGCTACTGGATTACACACTGACCTGTTATCCCTCAGTTAATGACAAATTCAGGAGGCTACTTAACATCCTTCCGGAAATACACGCAATGGCCGCACGAGGCGAGGAGCACCTCTACTCAAAGCATTGTGCTGGCAGTGCACCCACACAGACGCTGCTCATGGAGATGCTGCATGCCAAGCGGAAAGTGTAA
Protein Sequence
MLLEMDQQQATVQFISSLNLSPFSMQLEQQQPASPAHSNTNNANNSNNNNNSSNSNNNNNSSSNSNNNNSNNDNDTNALSNSDNDYSAYTLQLGSHQQQQQQHPHHTHHQQQQQQQQQQQQQHYQQQQQQNIANNNANAAANQFNASSYSYIYNFDSQYIFPTGYQETNSSHSQQSANGAGNAAAAGNSGQLLNGGSSSSTGNSYMLLPPGAGGTSAAAAAHMSGNVGGNPAAGVSGTAAGGGHHGGTSASSGGGEAIDFKHLFEELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNKKVYTCVAERSCHIDKTQRKRCPYCRFQKCLEVGMKLEAVRADRMRGGRNKFGPMYKRDRARKLQVMRQRQLALQALRSSMGTDIKPTPLSPGYQQAYPNMNIKQEIQIPQVSSLTQSPDSSPSPIAIALGQVNASGGGVIATPINAGNGNGGSSLGNGGNGNNNTNNSGTGSGSGGGGGGAGGGGNNTGGNNNITDGLQRNGNSSNSNSNSSCHEIGTGSLQNSAEAKLCFDSGTHPSSTADALIEPLRVSPMIREFVQSIDDREWQTQLFALLQKQTYNQVEVDLFELMCKVLDQNLFSQVDWARNTVFFKDLKVDDQMKLLQHSWSDMLVLDHLHHRIHNGLPDETQLNNGQVFNLMSLGLLGVPQLGDYFNELQNKLQELKFDMGDYVCMKFLILLNPDVRGIVNKKTVLEGHENVQAALLDYTLTCYPSVNDKFRRLLNILPEIHAMAARGEEHLYSKHCAGSAPTQTLLMEMLHAKRKV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00485910;
90% Identity
iTF_00508363;
80% Identity
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