Basic Information

Insect: Drosophila yakuba
Gene Symbol: -
Assembly: GCA_016746365.1
Location: NC:5099621-5108258[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.016 0.96 10.4 0.3 1 23 1254 1277 1254 1277 0.95

2 12 0.00025 0.015 16.1 2.7 2 23 1449 1470 1449 1470 0.97

3 12 9.7e-05 0.0059 17.4 0.2 3 23 1478 1498 1476 1498 0.98

4 12 8.1e-07 4.9e-05 23.9 4.1 2 23 1505 1526 1504 1526 0.97

5 12 7.6 4.6e+02 2.0 0.4 5 23 1539 1557 1537 1557 0.96

6 12 1.9 1.2e+02 3.9 5.4 3 23 1564 1585 1562 1585 0.93

7 12 0.2 12 7.0 0.2 2 23 1596 1616 1595 1616 0.96

8 12 0.00021 0.012 16.4 0.3 1 19 1622 1640 1622 1644 0.95

9 12 4.9e-05 0.003 18.3 0.4 1 23 1652 1674 1652 1674 0.98

10 12 0.00014 0.0088 16.9 7.6 1 23 1680 1702 1680 1703 0.96

11 12 0.00031 0.019 15.8 6.5 1 23 1708 1730 1708 1730 0.98

12 12 0.0037 0.23 12.4 6.1 1 23 1736 1758 1736 1759 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.016	0.96	10.4	0.3	1	23	1254	1277	1254	1277	0.95
2	12	0.00025	0.015	16.1	2.7	2	23	1449	1470	1449	1470	0.97
3	12	9.7e-05	0.0059	17.4	0.2	3	23	1478	1498	1476	1498	0.98
4	12	8.1e-07	4.9e-05	23.9	4.1	2	23	1505	1526	1504	1526	0.97
5	12	7.6	4.6e+02	2.0	0.4	5	23	1539	1557	1537	1557	0.96
6	12	1.9	1.2e+02	3.9	5.4	3	23	1564	1585	1562	1585	0.93
7	12	0.2	12	7.0	0.2	2	23	1596	1616	1595	1616	0.96
8	12	0.00021	0.012	16.4	0.3	1	19	1622	1640	1622	1644	0.95
9	12	4.9e-05	0.003	18.3	0.4	1	23	1652	1674	1652	1674	0.98
10	12	0.00014	0.0088	16.9	7.6	1	23	1680	1702	1680	1703	0.96
11	12	0.00031	0.019	15.8	6.5	1	23	1708	1730	1708	1730	0.98
12	12	0.0037	0.23	12.4	6.1	1	23	1736	1758	1736	1759	0.96

Sequence Information

Coding Sequence: ATGGTCGACAACAGTGTCCAATGCCCCGTGTGCACATTGTACCTGCATGCGGGAATGAATCTCTCCGATCACTTGGAGACCCATCCCAAGGAGCAGGTGATCAAGGCACTGGTGCAGATGACGATCGTTGGAAACGCTGGCAACAGTATGGGTAGTGTTCTCGCTGCCGCCATGTTGACAGGAGGAACTGGAGGTGGATCCAGCGGAGGCGAAGCCAGTGCTGATGAGAAACCGGCCGTCTTATCACCACCTTCTGGCGGCGATGTTAAACCAGTCGTGGTCAATACCATATCAGCTGCAACAGCGCCTGTGCcgccaccagcaccaccaccactatcCTCCTCCCTCGTGGCGGCCTGCTCCAACGTAGCCAGCTCTTCCACAACCAGCTCCACACCCACCTCCAACTCCgcaagcaacagcagcagcagcaaaccgAGCAATCCACCGATAAAAGCACTGAAATGCGCACCGTCCACGACTGAGGTGCGAGCCAGCTCATCCGCACATCCCACCACGAGTAGCGTGTCCACTTTGTACCAGCCGCAGGTCACTCCGGATTATCGcttcaaccagcagcagccgtCACAGACGACGGGCTTTGGGCGTGGTATCACCGCCTCAACAGCCGCGCTGGTAATTCCGCAGTTGCCTCAGCAGCACTTCCTCGCTAGCCATCAACAGCAGGCTCACTTTTCACATCAGCAGCccccgcagcaacagcagcagcagcatcagcctGCTCTGAAGTTCAGCTACGCCACAGCTTTGCCCCCACCTCCGCCGTTGCAGCTATTTacgcagcaacagcagacgGTTACTCCACCGCAGACCCAGCAGCAATCGCACCAGAAACCACCTCCCGCCTATGGAGCCGCCATTAGTCAAATTCGATCTCAGcacaaccaaaacaaacagcagcCACAGTCCCAAAGCGTGGCCATGCAACACAACCTAGCCCTGGCACCACCGACGACAGCAGCGGTCTCAACTTCacatgcaactgcagctgtcAAGCAGCCGAGTAAGCCGCAAACGGAAGTATTTCTGAatccgccaccaccgccgccggcaCAGCAACAGGTGCAGATCCACAATTTAGTGCAAAATCAGGGTCAACACCATCAGCTTCCTCAGTCGCAGCAGCCGAGCCAACAGAGTCACCAACAGCCACCGATCTTGCCGACCTACGGCTTAGGGGCCAGCAGTAGCTGCAGTTCCTCCAACAACCCCTCGACCTCGGGATCTGGTCTACGTTCAAATCGTCAGACAAACTCTCCGTTTGGAGCACTGCTTAATGCTGCAGCGGCAGTGGCCTGTGCATCGCCAGCCTGTTCCACCACCTCATCTTCGGTATTGCGGTATGCGGAATCACCGGTGGCACACTACCTTGAGCGGGACAATGGTGACTTCATTGTCCAGGAGACGCCGAAGCATATAGTTGAATGTGTGGAAAAAGAGGACGGCGAGTTCTCCGTGATCGAGCGCATTTATCAATCCCCGCCGAGTGTTCTGCACATacacgatgatgatgaggatgacgAGGATGAAGAGGAGGAAGACGAGCATGAAGCGCCACCCGAGGAAGAAGACGGGGACGATGAGCGGGAGGAAAACAGTCACAGCCGTAATATGAGCAAGACAACGAAAAAGGCCCGTAAGACAAAGCCGAAGCGAGGCTCCAAACGCACGTCGGACGAGGAGGAGTTCATGAGCCTTAGCAGCGGATGTGAGAGTGAGATGGAAAAAGAGCGTaagcaggagcagccaaaTGCCGCGGCATCACTACCACCTCCATTGTGCACGGCTCCTTCTACGAGTGCTGCTGGAGCTTCTACCTCCAATCTGGCGGACAATCATTCCAATTCCGCGTCCAACTCCGCCTCCAATTCTAACTCCACCGCCACTACAAAGTCCAAAAAGAATCGAATTACTGTACTGAGCGATGTTCCGCTTAATATGAATGAGTACCTAGATTTGATGGGCAACATTGTGGCCTCCAGTCGTATTGGGGCAAGTCGACCGTTTGCCGCTGTGGCTCCCATACCACTCGTCAAGGTGGAGAAGGAAGAGCCCTTGGATGATTACGACAACGTAGCATTGCCTGCTAATGCCGATCTGGAGCAAAAGCCCAGTCTTGAGCACGGCACTACCAGTGTCATTCGAATGGCAAGCACGGCTGCAGCACCTAGTTCAGCAACGGCGACAGAAGTGTCTCCCGAGGATCTCACACAGCCGCCGCCCATGAAAGTCGAGGTCGAGCCCACCACTACATTGTTACCGCAGCGCTTCTCAACTCCCGCTCAGCATCGTGGGCCTAAGAAATTAGTCatcaaaccaaaacaaacagcacCAGCGAATGCGACGACAACAAAAAAGACTGACAGACCATCTTCCCCCAGCAACAACCCATCCATATCAAGAGATCTGGTGCAGGTAAAGAGTGAAACCGTGGAGGCGCCAGCGCCGAGTAGTAGCAGCAGCATTCTGGAGAAGCACCTGACCACCAGCCGCAAACTGTTGCATCATCACTCGGCGGTGAACGACGACGATGCCCGGGTGCTGTTGGAGTTTGCGAACTCGAAGCAGCCGGCGCCACTGGCCGCAACCAGCACCACTTTCGTGGTAAATGCTAGTGCAGGTTTTCCCTCGGCGGGATCAGTTTTCGCCAGCAGCAGTAACAGCTGTTCCAAAGCACCGGCCAAGCCGGGCGAGGAGTACATCCTGCCGGACAACAACATGGACGTGGATGAGATTGTGATATCCTCGTCGTCTTCCTACACCTCCTCAGCAGCCCAGGTCCAAAACACGTTACAGCCGCCGGACTTTAACTTTCTGTACCACCAGGCCTCTACCACGGCCACGACGGCCACATACTTCAATCCCTTTTCCaggcagcagcatcatcatcagcagcagcacggGGTTAGCGATGCCACCAATGCGGCCACTTTGGCTTCGTCGTCCAGCAATTCAATGGACCACGACTCGATGAATGCTACATTCCGGGTGGCCAAGACCCAATCGCTGCAGTCATGGTACCAGCAAGAGCCAGAGCACGATCCACAGAATCAGGGTGGTGCGGAATCAGGAACAGCCACTCCCTCCAATCAGAGCCAGGATGTGGTCAGCCACCAGCCCACTAACTTTAACGCTGCTCTAGCGGCCGTCGATTGCTGTAACGTTGCTTTGGACGAGGATGCAAAATATCTTGACCTGGACGCCTGCAAGCGGGAGCAGCtgagcagcagtagcaaccTGCCCTCCGCTTCCGCGTCCACAACGTCGTCGTCGTTTGCTGGTGCTGGCACGGAAAGCAGTTTGGTGGGTGGTCTGAATATTCGCACCGATGAGAAGATGCCCGCTAAGGGTGAAATCTCCGAACAAGAAAGCAACTGCGACATCGAGAACTCCTGGAGTGAGTCGGTTTATGGGGACATTTCGCAGCGCTATTTCAGAAACCAGTTTTCTGGCGACTACAATCCTAATTGGCGGCAAGACTATTATCCGGCTCAGGATCTCAGCGCGCAGCAGAGGGAGCAAAAACGTTTTGACTTTAATGCTGTGGATGATGAGGCTTCATCTAGCTCGAGAAGGAGTCATCTGGAAGATGTCCTCCCGACAGCGGCCACCTCCTCTGCATGTACGTCAACGGCTATGCTGGCAGGTCCACCAATAGCTTCGACATCACGGGCTGCTGCTGAGGCGGCAGCGGAGGCGGCTGCTTTTGCCCAGCGAAAACCGCATCGTCGCAAGCTCTACAAGTGTCCTCACTGCGAGGCAATTTTCGAAAAGCTTAAAGAGCGCAATGCGCACATGATTGGCGAGCACAACTACGTGCGGCAAAATCGGCGTCTTATTTGCACTCAGCCGCAAATCAATACTTCGATGATACCGCCACAGCAGCAGATGATACTGCAGGGTGGTGAGGTTGAGGATTCCAAAGATGGCATAGTGAAGATAAAACAGGAGCAGTGCCAGGAAAAGCAGGATGTTGAACAAATGCGCGACCATTCCGAACTTTTGGCTGATGTCAAGGACTCCGAGCTGATGGGCATCGGCGGTGATGGTGACTGTGATGTGGATGATGACATTAAGCCACCCAACCAGCTAGATGAAAAGCCGACGCTGCCGCCATTAGCCATGACGACGCCAGCAGCTAAATTAGCAGCGTTGTATCGAATGCTCATCGCCTACAACGAATCCAAGCTCGGACAGGAGCGCAACAACCTTAGTGAGCTGGAGCAGAAGGCTATGGAAAAATCCATATTTCTTTGTTATGTCTGTCGTACCGATTTCCCGTCCGTAAAGCTCTATGACGCCCATCTCACCGAGCATCCCGCTGAATGCTTCACTTGCGGCAAGAAGTTCTACCGCTGGAAGAACTTCTCCTTGCACTTAAAGCGGCACTTGGGCTGGAAGGAGTTTGGATGCTACGTCTGCGACAAGAAGTTCGTGGTGCGCAGCGCCTTGGTCGAACACATGCGGATGCACACGGGGCAAACGCCTCTCAAGTGCAAGATATGCGGCAAAAAGTTCAAGCGCTACTCGAATCTGACGCAACACCGCAAGCGCCACACGAAAATGATGGTGCGCAAAAAGGAATACGTGTGCCACTGCGGTGAAGTCTTGCCCTCGAAGGCCCGCTTCCTGTGGCACAAGGAAACGCACGACCTGAAGCCGAAGTGCTGTCCGTACTGCTGCGATCGGTTTGTGCACGCCAACTCGCTACGTCGTCACATACGGCTGGCCCACTCTGATAAGTTTGACTACGCCGAACCTATGGAATGCCCCATGTGTAAGCAGATCTTCGCAAAGACGTCCATCAAGGCGCATATGGCGACGCATTCAACGGAGCCCCAATACGATTGCGCAATTTGTAGCAAGAGCTTCTCCACCAAATGGAATCTCAAGATCCACTCGTGGGTACACGCCAACCGGACGGCGAAGCCCTTTAAGTGCGAATACTGCCCAAAGGCATTCGTGCGAGAGCTGGACTTCAAAAACCACATCAACGCGCACAAGCAGATCAAGCCGTACACGTGCGAGTACTGCGGTTGCAAGTTTATCCGCAAGTACAACTACATGCGACATCGACGCGAACATCACGGCACCAAAAAGTTTACCTGTGACCAGTGCGATAAGTCTTTCCATCGACATTACTATCTGATAGAGCACCGGCGAATGCACACCGGAGAGCGTCCGTTCACGTGCACCATCTGCGGCAAAAGCTCCACTACCAAGACCAATCACAACAAGCATCTGAAGATCCACCATTCGCGCGATCCGTTCACGGTGGAGGCCTAA
Protein Sequence: MVDNSVQCPVCTLYLHAGMNLSDHLETHPKEQVIKALVQMTIVGNAGNSMGSVLAAAMLTGGTGGGSSGGEASADEKPAVLSPPSGGDVKPVVVNTISAATAPVPPPAPPPLSSSLVAACSNVASSSTTSSTPTSNSASNSSSSKPSNPPIKALKCAPSTTEVRASSSAHPTTSSVSTLYQPQVTPDYRFNQQQPSQTTGFGRGITASTAALVIPQLPQQHFLASHQQQAHFSHQQPPQQQQQQHQPALKFSYATALPPPPPLQLFTQQQQTVTPPQTQQQSHQKPPPAYGAAISQIRSQHNQNKQQPQSQSVAMQHNLALAPPTTAAVSTSHATAAVKQPSKPQTEVFLNPPPPPPAQQQVQIHNLVQNQGQHHQLPQSQQPSQQSHQQPPILPTYGLGASSSCSSSNNPSTSGSGLRSNRQTNSPFGALLNAAAAVACASPACSTTSSSVLRYAESPVAHYLERDNGDFIVQETPKHIVECVEKEDGEFSVIERIYQSPPSVLHIHDDDEDDEDEEEEDEHEAPPEEEDGDDEREENSHSRNMSKTTKKARKTKPKRGSKRTSDEEEFMSLSSGCESEMEKERKQEQPNAAASLPPPLCTAPSTSAAGASTSNLADNHSNSASNSASNSNSTATTKSKKNRITVLSDVPLNMNEYLDLMGNIVASSRIGASRPFAAVAPIPLVKVEKEEPLDDYDNVALPANADLEQKPSLEHGTTSVIRMASTAAAPSSATATEVSPEDLTQPPPMKVEVEPTTTLLPQRFSTPAQHRGPKKLVIKPKQTAPANATTTKKTDRPSSPSNNPSISRDLVQVKSETVEAPAPSSSSSILEKHLTTSRKLLHHHSAVNDDDARVLLEFANSKQPAPLAATSTTFVVNASAGFPSAGSVFASSSNSCSKAPAKPGEEYILPDNNMDVDEIVISSSSSYTSSAAQVQNTLQPPDFNFLYHQASTTATTATYFNPFSRQQHHHQQQHGVSDATNAATLASSSSNSMDHDSMNATFRVAKTQSLQSWYQQEPEHDPQNQGGAESGTATPSNQSQDVVSHQPTNFNAALAAVDCCNVALDEDAKYLDLDACKREQLSSSSNLPSASASTTSSSFAGAGTESSLVGGLNIRTDEKMPAKGEISEQESNCDIENSWSESVYGDISQRYFRNQFSGDYNPNWRQDYYPAQDLSAQQREQKRFDFNAVDDEASSSSRRSHLEDVLPTAATSSACTSTAMLAGPPIASTSRAAAEAAAEAAAFAQRKPHRRKLYKCPHCEAIFEKLKERNAHMIGEHNYVRQNRRLICTQPQINTSMIPPQQQMILQGGEVEDSKDGIVKIKQEQCQEKQDVEQMRDHSELLADVKDSELMGIGGDGDCDVDDDIKPPNQLDEKPTLPPLAMTTPAAKLAALYRMLIAYNESKLGQERNNLSELEQKAMEKSIFLCYVCRTDFPSVKLYDAHLTEHPAECFTCGKKFYRWKNFSLHLKRHLGWKEFGCYVCDKKFVVRSALVEHMRMHTGQTPLKCKICGKKFKRYSNLTQHRKRHTKMMVRKKEYVCHCGEVLPSKARFLWHKETHDLKPKCCPYCCDRFVHANSLRRHIRLAHSDKFDYAEPMECPMCKQIFAKTSIKAHMATHSTEPQYDCAICSKSFSTKWNLKIHSWVHANRTAKPFKCEYCPKAFVRELDFKNHINAHKQIKPYTCEYCGCKFIRKYNYMRHRREHHGTKKFTCDQCDKSFHRHYYLIEHRRMHTGERPFTCTICGKSSTTKTNHNKHLKIHHSRDPFTVEA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00529734;
90% Identity: iTF_00591878;
80% Identity: -