Dwil009509.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila willistoni
Gene Symbol
BTBD3
Assembly
GCA_018902025.1
Location
CM032166.1:27380888-27385577[-]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 2 5.4e-25 1.5e-22 80.0 0.0 4 108 268 376 266 378 0.93
2 2 5.9 1.6e+03 -0.6 0.0 77 108 377 408 375 410 0.83

Sequence Information

Coding Sequence
ATGATTGAAGCTTTTGCAAATCATTTAAGCAGTCATCTTGGACGACATCTATTCTATTGGGCCATTGATAGCACTGTGGTGCCACCAACTGGCAGCGTCGGCCTCAATCTGCGTCTCTCCGAGCTAATTAACAAATTTCACGGCCCCCTTGAACGGGGTGTGCAGGTGTTGGATCATTTGCTGACGCTCGAGGAGGACGATTTTGCTGGCCATTGGGGCAGCGCCTATGCCCACAATTATGAGCCAGAGTATGCGGCTCGTGTGCCGGAAAATCAAGAGATGCCGCCACCGGAATACATGGAGACTCTCAACAATGGCAACGGATTGCTGCACTCACCGCCTCACAATCATCAACAGCAGCAGCAGCAGCAACAACAAAGGGGTGGAGGAGTAGCTCTATCGCCACCAGGGGGAGGTGGACCATCGGGCAGTTCGGCGGATCACAATATACAAATAACTCAGCCAATTAGTGCACCATCTTCACCTCTAGCCTCACCGGGAGCTGTCAATGGTGGAGGAAGTGGTGGCGTCAGCGGCAGCGGACTCGGCGTTGGCATTGGCAGTCCAACTGCATTTTGCTTACCCTCCGGTTCGGGGGCGGCTCAAGCTGCGGCAGCGATAGCAGCCGCTGCAGCCACATTAAACACACATACGCCCACCAGCGGCAGTGGCTCGTATGTTTGCTCAGCTGGCACGAATAGTAGCAGCAGTTATGCGGCAGTTGGTGCATCTAATGCCATCGACACTGCCGATCCCAACTGGCAAGCCAGCAAGGCAACCGTATTAGAGCGAAATGCGGCCATGTTCAACAATGAATTGATGTCCGATGTCACCTTCGTTGTGGGTGGCGAATTTGATAATGATCCTGTACAAACAATACCCGCGCACAAATATATATTGGCCACAGGCAGCTCAGTCTTTTATGCCATGTTCTATGGTGGATTGGCGGAGAACAAGCAGGAAATCAAAGTGCCTGATGTAGAGCCCACAGCCTTTCTAACATTGTTAAGATACCTCTATTGTGATGAAATCAAATTGGAACCAGAACACATTTTGGCCACTCTTTATGCGGCTAAGAAGTATATTGTTCCCCATTTGGCTCGCGCATGCGTCAACTATCTCGAGGTTAAGTTGACGGCAAAAAACGCCTGCCTACTTCTCAGTCAATCGCGTCTTTTCGAGGAGCCCGAACTGATGCAGCGTTGCTGGGAAGTGATCGACGCTCAGGCCGAGATGGCGGTTAAGTCCGAGGATTTCGTGGATATTGATCTAAAGACGTTCGAGTCGATATTGTCACGCGAGACGCTAAATTGCAAGGAGATTCATCTGTTTGAGGCCGCCCTAAATTGGGCCCTCAATGCCTGCGAGAAGATGAGCATCGATGAGACGCCCCAGAATAAACGTAGATTGCTGGGACAAGCATTGCATTTAATACGTATACCCACAATGACGCTCGAGGAGTTTGCCAATGGAGTGGCTCAGACAGGGATTCTAACGTCCCAGGAGACAATTGACATGTTTTTGCATTTTACAGCGAAAGTGAAGCCAATTTTGGGTTTCCCAACACGTTCCCGTGCCGGTCTAAAGACCCAAGTGTGCCATCGCTTTCAATCGTGTGCGTATCGCTCGAATCAGTGGCGCTACCGTGGACGCTGTGATTCCATACAATTTTCAGTGGATCGTCGCATTTTCATTGTTGGCTTTGGACTCTATGGATCCTCAACAGGGGCTGCCAATTACAATGTCAAGATTGAGCTCAAACGTCTGGGACGCACACTGGCCGAAAATGATACAAAATTCTTCTCGGATGGCTCTAGCAATACCTTCCATGTATTCTTCGAGAATCCCATACAAATTGAGCCCGAATGCTATTACACTGCATCGGTAATACTCGATGGCAATGAGCTGAGCTTCTTTGGCCAAGAGGGCATGTCCGAGGTGCTGATGGGTAATGTGACATTCCAGTTCCAATGCTCATCGGAAAGTACGAATGGCACTGGAGTGCAAGGTGGCCAGATACCGGAATTGATATTCTATGGGCCAACTAGTCCTGTTACCGCTTTAAGTTCACCAACAAATTCATTGTGTGCCACGCCTATTGGCGGTGGTGGTATAAGTGGAATGATTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGAGACCAACAACAGCAACAAACAAAGCACAGAATATACAAAACAGAAGAAACTCATGGGTTTTCAGTGCCAGTCAACAGGGCAAATTGGAGTTTTAA
Protein Sequence
MIEAFANHLSSHLGRHLFYWAIDSTVVPPTGSVGLNLRLSELINKFHGPLERGVQVLDHLLTLEEDDFAGHWGSAYAHNYEPEYAARVPENQEMPPPEYMETLNNGNGLLHSPPHNHQQQQQQQQQRGGGVALSPPGGGGPSGSSADHNIQITQPISAPSSPLASPGAVNGGGSGGVSGSGLGVGIGSPTAFCLPSGSGAAQAAAAIAAAAATLNTHTPTSGSGSYVCSAGTNSSSSYAAVGASNAIDTADPNWQASKATVLERNAAMFNNELMSDVTFVVGGEFDNDPVQTIPAHKYILATGSSVFYAMFYGGLAENKQEIKVPDVEPTAFLTLLRYLYCDEIKLEPEHILATLYAAKKYIVPHLARACVNYLEVKLTAKNACLLLSQSRLFEEPELMQRCWEVIDAQAEMAVKSEDFVDIDLKTFESILSRETLNCKEIHLFEAALNWALNACEKMSIDETPQNKRRLLGQALHLIRIPTMTLEEFANGVAQTGILTSQETIDMFLHFTAKVKPILGFPTRSRAGLKTQVCHRFQSCAYRSNQWRYRGRCDSIQFSVDRRIFIVGFGLYGSSTGAANYNVKIELKRLGRTLAENDTKFFSDGSSNTFHVFFENPIQIEPECYYTASVILDGNELSFFGQEGMSEVLMGNVTFQFQCSSESTNGTGVQGGQIPELIFYGPTSPVTALSSPTNSLCATPIGGGGISGMIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRPTTATNKAQNIQNRRNSWVFSASQQGKLEF

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00571244; iTF_00503348; iTF_00916321; iTF_00518530; iTF_00542530; iTF_00557289; iTF_00499672; iTF_00577147; iTF_00498240; iTF_00914594; iTF_00607171; iTF_00560385; iTF_00525254; iTF_00482343; iTF_00574154; iTF_00583050; iTF_00513550; iTF_00619951; iTF_00495217; iTF_00566897; iTF_00610002; iTF_00570483; iTF_00576435; iTF_00517077; iTF_00552405; iTF_00514262; iTF_00528150; iTF_00548919; iTF_00593209; iTF_00498970; iTF_00500410; iTF_00535418; iTF_00485947; iTF_00497500; iTF_00558814; iTF_00543839; iTF_00522304; iTF_00609251; iTF_00483065; iTF_00508420; iTF_00523780; iTF_00832260; iTF_00804485; iTF_01324229; iTF_01322018; iTF_00501894; iTF_00553124; iTF_00511377; iTF_00598246; iTF_00561124; iTF_00567623; iTF_00495949; iTF_00547443; iTF_00541844; iTF_01554790; iTF_00564743; iTF_00569767; iTF_00586055; iTF_00617735; iTF_00494472; iTF_00588232; iTF_00501128; iTF_00555930; iTF_00520008; iTF_00577864; iTF_00591048; iTF_00483776; iTF_00806056; iTF_01553320; iTF_00517801; iTF_01319849; iTF_01326506; iTF_00484523; iTF_00473874; iTF_00471708; iTF_00491595; iTF_00564011; iTF_00594635; iTF_00915435; iTF_00488748; iTF_00538316; iTF_00915436; iTF_00600397; iTF_00611437; iTF_01320557; iTF_00507694; iTF_00601902; iTF_00493040; iTF_00524496; iTF_00530352; iTF_00614992; iTF_00546053; iTF_01327984; iTF_01321283; iTF_01325010; iTF_00496721; iTF_00529649; iTF_00590321; iTF_00490162; iTF_00505490; iTF_00603442; iTF_00489459; iTF_00597491; iTF_00598963; iTF_01322739; iTF_01556211; iTF_01570323; iTF_00519252; iTF_01559124; iTF_00506966; iTF_00521495; iTF_00536119; iTF_00585303; iTF_00608535; iTF_00558008; iTF_00583773; iTF_00802936; iTF_00492345; iTF_00596025; iTF_00601145; iTF_00514980; iTF_00486650; iTF_00533178; iTF_00536859; iTF_00584507; iTF_00616283; iTF_00904827; iTF_00919899; iTF_01325755; iTF_00474588; iTF_00512092; iTF_00527388; iTF_00592476; iTF_00612158; iTF_00515679; iTF_00525951; iTF_00580831; iTF_00605663; iTF_00504774; iTF_00555168; iTF_00604180; iTF_00574912; iTF_00587488; iTF_00619232; iTF_00550337; iTF_00591779; iTF_00596740; iTF_00539049; iTF_00477419; iTF_00604939; iTF_00607856; iTF_00602686; iTF_00539743;
90% Identity
iTF_00591048;
80% Identity
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