Dsal021365.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila saltans
Gene Symbol
BTBD3
Assembly
GCA_018903575.1
Location
JAEIGH010000009.1:3369207-3373700[-]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 2 2.8e-25 1.1e-22 80.8 0.0 4 108 209 317 207 319 0.93
2 2 4.5 1.8e+03 -0.3 0.0 77 108 318 349 316 351 0.83

Sequence Information

Coding Sequence
ATGGCCAACAACAATCATAGTAATAATAATGGCAATAATAATGCCCTGAATCGTCTCTCCCTGAAATCGGCCAACAAACGTAACCAGGAATCCATGTCACATTCCCAGCCAAATGGCGGCTGGATAAACGTGGAGACACTCAACAACGGTAATGGATTACTGCACTCACCGCCCCACAATCATCAACAGCAACAGCAGCAACAACAAAGGGGGGTGGCTCTCTCGCCACCAGGAGGGGTTGGAGGTGGAAGTGGCGCATCGGGCAGTTCGGTAGATCACAATATTCAAATAACACAACCAATTAGTGCACCATCTTCGCCTCTGGCCTCACCGGGTGCAGTAAATGGAGGCGGCAGCAGTACTGGTGTTGGAGGGGGCATTGCCAGTCCGACAGCGTTTTGCCTGCCCTCCGGATCGGGGGCAGCACAAGCTGCAGCAGCAATAGCAGCCGTCGCATCAACTTTAACAACACATACGCCCACAAGCGGCAGTGGCTCATATGTTTGCTCAGCTGGCACAAATAGTAGCAGCAGCTATGCGGCAGTTGGTGCCTCCAATGCCATTGACACGGCCGATCCCAATTGGCAGGCCAGCAAGGCGACAGTACTAGAGCGCAATGCGGCCATGTTCAACAATGAACTGATGTCGGATGTCACCTTTGTAGTGGGCGGCGAGTTCGATAATGATCCTGTACAAACAATACCCGCGCACAAATATATACTGGCTACAGGCAGCTCAGTCTTTTATGCTATGTTCTATGGCGGATTGGCGGAGAACAAGCAGGAAATCAATGTGCCTGATGTTGAGCCAACAGCCTTCCTAACACTGTTAAGATACCTCTATTGTGATGAAATCAAACTCGAACCCGAACACATTCTGGCTACGCTGTATGCCGCTAAAAAATATATTGTTCCCCATTTGGCTCGTGCCTGCGTCAACTATCTGGAGGTTAAGTTGACGGCAAAAAACGCCTGCCTACTTCTCAGTCAATCGCGTCTCTTCGAGGAGCCCGAACTGATGCAACGTTGCTGGGAAGTGATCGATGCGCAGGCCGAGATGGCGGTTAAATCCGAAGATTTTGTGGACATTGATCTGAAAACGTTTGAGTCGATATTGTCGCGCGAGACGCTAAATTGCAAGGAGATTCATCTGTTTGAAGCTGCTCTGAATTGGGCTCTCTATGCCTGCAAGACAAAAGGCATCGATGAGACGGCGCAGAACAAACGTCGACTGTTGGGCCAGGCATTGCATTTAATTCGCATACCCACCATGACGCTGGAAGAGTTCGCCAATGGTGTGGCTCAGACAGGGATTCTCACATCGCAGGAGACAATTGATATGTTCTTGCATTTTACGGCAAAAGTGAAACCGAATTTGGGTTTTCCGACACGTTCTCGAGCTGGTCTGAAGACCCAAGTGTGCCATCGCTTCCAATCTTGTGCGTATCGTTCGAATCAGTGGCGTTACCGCGGACGTTGTGATTCCATACAGTTCTCAGTTGATCGTCGCATTTTCATTGTTGGCTTTGGCCTGTACGGATCCTCCACAGGTGCTGCCAATTACAATGTAAAGATTGAACTTAAGCGTCTGGGTCGAACACTTGCCGAGAATGATACAAAATTCTTTTCGGATGGCTCTAGCAATACCTTCCATGTATTCTTCGAGAATCCCATACAAATTGAGCCTGAATGCTATTATACCGCCTCCGTTATACTCGATGGCAATGAGTTGAGCTTCTTTGGCCAAGAGGGCATGTCCGAGGTTCTTATGGGTAATGTGACATTCCAGTTCCAGTGCTCTTCGGAGAGCACTAATGGCACCGGTGTCCAGGGTGGTCAGATACCGGAATTGATCTTCTATGGACCAACTAGTCCCGTTACAGCATTAAGTTCGCCAACAAATTCGATGTGTGCCACGCCCATTGGAGGTGGTGGTATTACTGGAATGATTGGAGCAAGCGGCACCACAAATGGAAGCAACGGAGGTGCAGCAACAACATCAGCCCCAGCAACGGTAACAACAATCGTTGGTGGCAATAATGCTGGCGAGGAATTGGCAGAGACCACCACCGGGAGTGGCAGTAGCAGCAGCACCTGA
Protein Sequence
MANNNHSNNNGNNNALNRLSLKSANKRNQESMSHSQPNGGWINVETLNNGNGLLHSPPHNHQQQQQQQQRGVALSPPGGVGGGSGASGSSVDHNIQITQPISAPSSPLASPGAVNGGGSSTGVGGGIASPTAFCLPSGSGAAQAAAAIAAVASTLTTHTPTSGSGSYVCSAGTNSSSSYAAVGASNAIDTADPNWQASKATVLERNAAMFNNELMSDVTFVVGGEFDNDPVQTIPAHKYILATGSSVFYAMFYGGLAENKQEINVPDVEPTAFLTLLRYLYCDEIKLEPEHILATLYAAKKYIVPHLARACVNYLEVKLTAKNACLLLSQSRLFEEPELMQRCWEVIDAQAEMAVKSEDFVDIDLKTFESILSRETLNCKEIHLFEAALNWALYACKTKGIDETAQNKRRLLGQALHLIRIPTMTLEEFANGVAQTGILTSQETIDMFLHFTAKVKPNLGFPTRSRAGLKTQVCHRFQSCAYRSNQWRYRGRCDSIQFSVDRRIFIVGFGLYGSSTGAANYNVKIELKRLGRTLAENDTKFFSDGSSNTFHVFFENPIQIEPECYYTASVILDGNELSFFGQEGMSEVLMGNVTFQFQCSSESTNGTGVQGGQIPELIFYGPTSPVTALSSPTNSMCATPIGGGGITGMIGASGTTNGSNGGAATTSAPATVTTIVGGNNAGEELAETTTGSGSSSST

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00618496;
90% Identity
iTF_00523780; iTF_00501128; iTF_00571244; iTF_00600397; iTF_00503348; iTF_00618496; iTF_00917301; iTF_00916321; iTF_00914594; iTF_00919899; iTF_00612158; iTF_00483776; iTF_00577864; iTF_00555930; iTF_00555168; iTF_00604180;
80% Identity
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