Basic Information

Insect: Drosophila vulcana
Gene Symbol: Hr39
Assembly: GCA_008042555.1
Location: VNJP01009416.1:97264-100096[+]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 0.27 3.7e+03 -2.4 7.3 40 159 185 306 171 371 0.49

2 3 1.2e-10 1.7e-06 28.4 0.0 1 42 471 516 471 523 0.86

3 3 2.2e-88 3e-84 284.4 3.2 87 408 518 802 507 802 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	0.27	3.7e+03	-2.4	7.3	40	159	185	306	171	371	0.49
2	3	1.2e-10	1.7e-06	28.4	0.0	1	42	471	516	471	523	0.86
3	3	2.2e-88	3e-84	284.4	3.2	87	408	518	802	507	802	0.91

Sequence Information

Coding Sequence: ATGCCGAACATGTCCAGCATCAAGACGGAGCAGCAGAGTGCTTCACTCGGCGGTGGCTATCAGCTGCCAGTCAATATGTGCACCACCACCGCTtccacgacgacgacaacgctgggaggaggaggaggaggaggagcaagtGGAACCACCGGATCGAGGCACAATGTGTCCGTGACTAACATCAAGTGCGAGTTGGACGAACTGCCCACGCCCAACGGCAACCTAGTGCCAGTGATTGCCAACTATGGTCACGGCAGCCTGCGCATACCGCTGAGTGGCGGTCCACCGCCCAACCACGAGGAGGAGTCCGATTCGGAGGCAGAGCTGGCGAACATTGAGAACCTAAAAGTGCGACGGCGGGCGGCGGACAAGAACGGGCCAAGGCCCATGTCATGGGAGGGGGAGCTGAGCGAACCGGAGGccaatggcggcggcggcgacgagGAGCTGATGGAGACGGAGCCGACGATTAAAAGCGAGTTACTCGCCGGCGGAGGAGCACCCCTGCAGCCCGCTTGTGCTCTGCAGCCGATCAAAACCGAGCTGGAGAACATAGCAGgcgaactgcagcagcagcagcaactgcagcagggAAAGGCCTTCCCCCtgaccagcagcaccaccaccaccacctcccaATCACTCGCCGCGAACCCCAAACTTAAGCTGGCGCCCACGCAAAGCGATCCCATTAATCTCAAGTTTGAACCGCCGCTGGGTGACAACTCGCCGCTGCTGGCCGCTCGCAGCAAGTCGAGCAGCGGTGGCCACTTGCCGCTCCCTGCGAATCCCAGTCCCGACTCCGCCATACATTCCGTCTACACGCACAGTTCGCCATCGCAGTCGCCGCTGACCTCGCGCCACGCCCCGTACACGCCCTCGCTGAGTCGAAACAACAGCGACGCCTCGCACAGCAGctgctacagctacagctccGAGTTCAGTCCCACCCACTCACCCATCCAGGCGCGACATGCCCCCCCTGCAGGCTCGCTTTACGGCAACGGCGGCGTGCATCATCACAGTGTGCTGTATCGCCCCCTGAAGGTGGAGGCCTCGTCCACGGGGCCACCGTCTGGTAGCCAGGAGGCGCAAAATTTAAGCATGGACTCCATTTCCAATGGTTTGGATGCCACGGGTTCTGGTTCATCGCTGCCCGCTTCGCCGGCAGGCATATCGCGCCAGCAGCTCATCAACTCACCGTGTCCCATTTGCGGCGACAAGATCAGCGGCTTCCACTACGGCATCTTCTCCTGCGAGTCCTGCAAGGGGTTCTTCAAGCGCACCGTGCAAAACCGCAAGAACTATGTGTGCGTGCGTGGCGGTCCCTGCCAGGTGAGCATCTCTACGAGGAAGAAGTGCCCGGCCTGTCGGTTTGAGAAGTGTCTGCAGAAGGGCATGAAGCTGGAGGCCATTCGCGAGGATAGGACGCGCGGCGGTCGCTCCACCTACCAGTGTTCGTACACGCTTCCCAACTCGATGCTCAGTCCGCTGTTAACCAGCCCGAATTTGGGTGGGGCTTCCATCAAGACGGAGGACGTCACGGCCACGGAGGCGGCGGGCAAGCAGAGTCTGCGAACTGGCAACGTGCCGCCGCTACTGCAGGAAATCATGGATGTTGAACATCTTTGGCAGTACACCGATGCCGAGCTGGCTCGCATTAACCAACCGTTGTCCGCATTTGCTTCCGGCAGTTCTTCTTCGTCGTCATCCTCGTCAGCCACTTCATCATCAGGCGCCAACCAGGgacagccgcagccgcagctgaCCAATCCACTGCTGGCCAGTGCCGGTCTCTCGTCCAACGGCGAAAACGCCAATCCCGATCTGATTGCCCATCTTTGCAATGTGGCCGATCATCGTCTCTACAAGATTGTCAAATGGTGCAAAAGTTTGCCGCTCTTTAAGAACATTTCGATTGATGATCAGATTTGCCTGCTCATCAATTCGTGGTGCGAACTGTTGCTCTTCTCCTGCTGTTTTCGTTCGATCGACACTCCCGGGGAAATCAAGATGTCGCAAGGCAGAAAGATAACGCTGTCGCAGGCGAAATCAAATGGCTTGCAGACCTGCATTGAACGTATGCTCAATCTGACAGATCACCTGCGGCGTTTACGCGTTGATCGCTACGAATATGTTGCCATGAAGGTGATTGTGCTGTTGCAGTCAGATACCACAGAGCTTCAGGAGGCAGTAAAGGTTCGGGAATGCCAGGAGAAAGCATTGCAGAGCTTGCAGGCATACACCTTGGCCCACTATCCCGACACGCCTTCAAAGTTTGGGGAGCTACTGTTGCGCATTCCGGATCTGCAGCGTACGTGCCAGttgGGAAAAGAGATGCTGACGATCAAGACTCGCGATGGCGCCGATTTCAATTTGCTGATGGAGCTCTTGCGCGGAGAACATTGA
Protein Sequence: MPNMSSIKTEQQSASLGGGYQLPVNMCTTTASTTTTTLGGGGGGGASGTTGSRHNVSVTNIKCELDELPTPNGNLVPVIANYGHGSLRIPLSGGPPPNHEEESDSEAELANIENLKVRRRAADKNGPRPMSWEGELSEPEANGGGGDEELMETEPTIKSELLAGGGAPLQPACALQPIKTELENIAGELQQQQQLQQGKAFPLTSSTTTTTSQSLAANPKLKLAPTQSDPINLKFEPPLGDNSPLLAARSKSSSGGHLPLPANPSPDSAIHSVYTHSSPSQSPLTSRHAPYTPSLSRNNSDASHSSCYSYSSEFSPTHSPIQARHAPPAGSLYGNGGVHHHSVLYRPLKVEASSTGPPSGSQEAQNLSMDSISNGLDATGSGSSLPASPAGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCVRGGPCQVSISTRKKCPACRFEKCLQKGMKLEAIREDRTRGGRSTYQCSYTLPNSMLSPLLTSPNLGGASIKTEDVTATEAAGKQSLRTGNVPPLLQEIMDVEHLWQYTDAELARINQPLSAFASGSSSSSSSSSATSSSGANQGQPQPQLTNPLLASAGLSSNGENANPDLIAHLCNVADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSIDTPGEIKMSQGRKITLSQAKSNGLQTCIERMLNLTDHLRRLRVDRYEYVAMKVIVLLQSDTTELQEAVKVRECQEKALQSLQAYTLAHYPDTPSKFGELLLRIPDLQRTCQLGKEMLTIKTRDGADFNLLMELLRGEH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00492281;
90% Identity: iTF_00590268;
80% Identity: iTF_00617697;