Druf000538.1
Basic Information
- Insect
- Drosophila rufa
- Gene Symbol
- Hr39
- Assembly
- GCA_018153105.1
- Location
- JAECXS010000096.1:5780774-5784352[+]
Transcription Factor Domain
- TF Family
- SF-like
- Domain
- zf-C4|SF-like
- PFAM
- AnimalTFDB
- TF Group
- Zinc-Coordinating Group
- Description
- The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 3 0.15 1.1e+03 -1.6 5.4 58 154 258 300 159 391 0.44 2 3 6.8e-11 5.2e-07 29.2 0.0 1 46 458 507 458 513 0.86 3 3 4e-90 3.1e-86 290.1 0.5 81 408 498 792 489 792 0.90
Sequence Information
- Coding Sequence
- ATGCCGAACATGTCCAGCATCAAGACGGAGCAGCAGCCGAGCGCTTCGCTCGGAGTAACCGGCTATCAGCTGCCGGTCAACATGTGCACCACCACCGCGTCCACGACGACGACCACGCTGGCCACCGGATCGAGGCACAATGTGTCCGTGACCAACATCAAGTGCGAGCTGGACGAGGTGCCCACGCCCAACGGCAACCTGGTGCCGGTGATTGCCAACTACGGCCACGGCAGCCTGCGCATCCCGCTGAGCGGCGGCGTCGCCCCGAACCATGAGGAGGAGTCCGATTCGGAGGCGGAGCTGGCGAACATCGAGAACCTGAAGGTGCGACGGCGGGCGGCGGACAAGAATGGGCCGCGGCCCATGTCATGGGAAGGCGAGCTGAGCGAACCGGAGGCCAATGGCGGTGGCGACGAGGAGGAGCTGATGGAGACGGAGCCGACGATCAAGAGCGAGGTGCTGGCCAGCGCGCCAGCAAACCTGCAACCCGCCTGCGCTCTGCAGCCGATCAAGACCGAGCTGGAGAACATCGCAGGCGAGCTGCAGCAGCAGCAGCAGCAGGGAAAGGGCTATCCCCTGGCCACCACCCTGACCACCTCCCAGACGCACTCGGCGAACCCCAAACTGAAGCTGGCGCCCACGCAAAGTGATCCCATCAATCTCAAGTTCGAGCCGCCGCTGGGCGACAACTCGCCGCTGCTGGCCGCCCGCAGCAAGTCGAGCAGCGGTGGCCACCTGCCGCTGCCCGCGAATCCCAGTCCCGACTCCGCCATACATTCCGTCTACACGCACAGCTCGCCATCGCAGTCGCCGCTGACCTCGCGCCACGCCCCCTACACGCCCTCGCTGAGTCGGAACAACAGCGACGCCTCGCACAGCAGCTGCTACAGCTACAGCTCCGAGTTCAGCCCCACCCACTCGCCCATCCAGGCGCGACATGCCCCCCCGGCGGGATCGCTCTACGGCAACGGCGGCGGCGTGCATCATCACAGCGTGCTCTATCGCCCGCTGAAGGTGGAGGCCGCCTCGTCCACGGGCAGCCAGGATTCGGCGCAAAATCTGAGCATGGACTCGATATCCAATGGTCTGGATACGACGGGCTCTGGCTCATCGCTACCCGCCTCGCCGGCTGGGATTTCGCGGCAGCAGCTTATCAACTCGCCGTGCCCCATCTGCGGCGACAAGATCAGCGGCTTCCACTACGGCATCTTCTCCTGCGAGTCCTGCAAGGGGTTCTTCAAGCGCACCGTGCAGAACCGCAAGAACTATGTGTGCGTGCGCGGGGGTCCCTGCCAGGTGAGCATCTCCACGCGCAAGAAGTGCCCGGCCTGCCGGTTCGAGAAGTGCCTGCAGAAGGGCATGAAGCTGGAGGCCATACGCGAGGATCGGACACGCGGCGGTCGCTCCACCTACCAGTGCTCCTACACGCTGCCCAACTCGATGCTCAGTCCGCTGCTGACCAGCCCGAACCTGGGGGGAGCTTCCATCAAGACGGAGGACGTGGCCACGACGGAGGCGGGCAAGCAGGGTCTGCGAACTGGCAACGTGCCGCCGCTACTGCAGGAAATCATGGATGTTGAACATCTCTGGCAGTACACCGATGCCGAGCTGGCCCGCATTAACCAACCGCTGTCCGCCTTTGCCTCCGGCAGCTCCTCGTCATCGTCATCCTCGTCCGCCACTTCGTCAGGCGCCGCCAACCACGGACAGCCGCAGCAGCAGCCGCAGCCGCAGCTGACCAACCCACTGCTGGCCAGTGCCGGTCTCTCGTCCAACGGCGAGAACGCCAATCCCGACCTGATTGCCCATCTCTGCAACGTGGCCGATCATCGCCTCTACAAGATTGTCAAATGGTGCAAGAGCCTGCCGCTCTTCAAGAACATTTCGATCGATGATCAGATCTGTCTGCTCATCAATTCGTGGTGCGAACTGCTGCTCTTCTCCTGCTGCTTCCGATCGATCGACACTCCCGGCGAAATCAAGATGTCGCAAGGCAGAAAGATAACCCTGTCGCAGGCCAAATCCAATGGCTTGCAGACCTGCATTGAACGGATGCTTAACCTGACGGATCACCTGCGGCGATTACGCGTTGACCGCTACGAATATGTTGCCATGAAGGTGATTGTGCTGTTGCAGTCAGATACTACGGAGCTGCAGGAGGCGGTGAAGGTGCGGGAGTGCCAGGAGAAGGCGTTGCAGAGCCTGCAGGCCTACACCTTGGCCCACTATCCCGACACGCCGTCCAAGTTTGGCGAGCTCCTGCTGCGCATTCCCGATCTGCAGCGAACGTGCCAGCTGGGCAAGGAGATGCTGACGATCAAGACTCGCGATGGCGCCGACTTCAACTTGCTGATGGAGCTCTTGCGCGGAGAGCATTGA
- Protein Sequence
- MPNMSSIKTEQQPSASLGVTGYQLPVNMCTTTASTTTTTLATGSRHNVSVTNIKCELDEVPTPNGNLVPVIANYGHGSLRIPLSGGVAPNHEEESDSEAELANIENLKVRRRAADKNGPRPMSWEGELSEPEANGGGDEEELMETEPTIKSEVLASAPANLQPACALQPIKTELENIAGELQQQQQQGKGYPLATTLTTSQTHSANPKLKLAPTQSDPINLKFEPPLGDNSPLLAARSKSSSGGHLPLPANPSPDSAIHSVYTHSSPSQSPLTSRHAPYTPSLSRNNSDASHSSCYSYSSEFSPTHSPIQARHAPPAGSLYGNGGGVHHHSVLYRPLKVEAASSTGSQDSAQNLSMDSISNGLDTTGSGSSLPASPAGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCVRGGPCQVSISTRKKCPACRFEKCLQKGMKLEAIREDRTRGGRSTYQCSYTLPNSMLSPLLTSPNLGGASIKTEDVATTEAGKQGLRTGNVPPLLQEIMDVEHLWQYTDAELARINQPLSAFASGSSSSSSSSSATSSGAANHGQPQQQPQPQLTNPLLASAGLSSNGENANPDLIAHLCNVADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSIDTPGEIKMSQGRKITLSQAKSNGLQTCIERMLNLTDHLRRLRVDRYEYVAMKVIVLLQSDTTELQEAVKVRECQEKALQSLQAYTLAHYPDTPSKFGELLLRIPDLQRTCQLGKEMLTIKTRDGADFNLLMELLRGEH
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00483029;
- 90% Identity
- iTF_00590285; iTF_00617681; iTF_00617697; iTF_00480217; iTF_00480197; iTF_00606367; iTF_00606345;
- 80% Identity
- iTF_00590285;