Dvii009632.1
Basic Information
- Insect
- Drosophila virilis
- Gene Symbol
- -
- Assembly
- GCA_007989325.2
- Location
- CM017607.2:9817238-9823417[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 17 1.6e-05 0.00092 19.2 2.1 1 23 242 264 242 264 0.97 2 17 5.1e-06 0.0003 20.7 0.4 1 23 270 292 270 292 0.97 3 17 0.00076 0.045 13.9 0.9 1 23 298 320 298 320 0.95 4 17 1.1e-05 0.00064 19.7 3.1 1 23 326 348 326 348 0.97 5 17 2.5e-05 0.0015 18.6 4.7 1 23 354 376 354 376 0.99 6 17 4.5e-05 0.0027 17.8 5.7 1 23 382 404 382 404 0.97 7 17 2.2e-07 1.3e-05 25.0 4.3 1 23 410 432 410 432 0.98 8 17 7.9e-08 4.7e-06 26.4 2.4 1 23 438 460 438 460 0.97 9 17 4.6e-05 0.0027 17.7 6.7 1 23 466 488 466 488 0.97 10 17 8e-05 0.0048 17.0 6.5 1 23 494 516 494 516 0.98 11 17 5.2e-06 0.00031 20.7 8.1 1 23 522 544 522 544 0.98 12 17 4.2e-06 0.00025 21.0 7.6 1 23 550 572 550 572 0.97 13 17 4.7e-07 2.8e-05 24.0 7.7 1 23 578 600 578 600 0.98 14 17 0.00015 0.0088 16.1 9.5 1 23 606 629 606 629 0.95 15 17 5.2e-05 0.0031 17.5 0.9 1 23 635 657 635 657 0.98 16 17 0.00057 0.034 14.3 3.4 1 23 667 689 667 689 0.97 17 17 6.5e-06 0.00039 20.4 1.6 1 23 695 718 695 718 0.96
Sequence Information
- Coding Sequence
- ATGCAGCACGTGAGCGCTGCCAGTTCGGCACCTTCGGTGGTTTCAGCACCGGTGGTGACCACTGGCGGTGGCACCACCATCACTTTGGGCGGACCGCCGCCATTGCCCGGCAGCAAATCAGATCATAAAGAGGACGGCGGCAAGCCGCCACACGGCATTGAAATGTATAAAGTGAACATTGAGGATATATCACAGTTATTTACGTATCACGAGGTCTTTGGCAAAATCCATGGCGATGTGGTGAATCATGTGGCGGCGGTGCATGGCAGCCAGCTGCCACCGCCGCAgctgccaccgccaccgccattACCGCCGCAGACGACGCATTCGGCtagcgcagctgcagcagcagcggcggcgtccACAAATAATGCAGCCGTCGCTGCTGTAATGGCATCCGCCAATGCAGCAGCCGCGGCTGCAGCGGCCGCCTCAGCGGCGGCCACagcccaacagcaacagcagcaacagcaagccCCAGCGACAAGCACAAATGCTGGATCACAACAGGGCAGCGCCACGGTGACCACGACTAGCTCTGGCAGCAACGGGGGGAATGGGggccagaacaacaacaacaacaacaacaacaataacaacaactcgacaacgacgacgacgggtGAGTTGCTAATGCCGAAAATGGAGGGCGGCATTCATGGCGTCGATGGGCAATCGAGCGTTGCGTTGGCGCCGGATGGCACGCCCATAGCGACTGGTACGCATGTGTGCGACATTTGTGGCAAAATGTTCCAGTTTCGCTATCAGCTGATTGTGCACCGTCGCTACCACAGCGAGCGCAAGCCGTTTATGTGTCAGGTATGCGGTCAGGGTTTTACCACATCGCAGGATTTGACCCGCCATGGGAAGATCCATATTGGCGGTCCCATGTTCACTTGCATTGTGTGCTTCAATGTGTTTGCCAATAATACGAGTCTGGAGCGCCATATGAAACGGCATTCAACGGACAAGCCATTCGCCTGCACCATTTGCCAAAAGACTTTCGCACGCAAAGAGCATCTGGACAATCATTTTCGTTCGCATACGGGCGAAACACCGTTCCGTTGTCAGTACTGCGCCAAGACGTTTACGCGCAAGGAGCACATGGTTAATCATGTGCGCAAACACACGGGTGAGACGCCACATCGTTGCGATATTTGTAAGAAGTCCTTCACGCGCAAGGAACACTATGTTAACCACTACATGTGGCACACTGGTCAAACACCGCATCAGTGCGATGTCTGCGGCAAGAAATACACGCGCAAGGAGCACCTAGCCAACCATATGCGCTCCCACACCAACGAGACGCCGTTTCGTTGCGAAATCTGCGGCAAGAGCTTTAGTCGCAAGGAGCATTTCACCAATCACATACTCTGGCATACAGGCGAGACGCCGCATCGGTGCGACTTCTGCTCCAAGACGTTTACGCGCAAGGAGCATTTGTTAAATCACGTGCGCCAGCACACGGGAGAGTCGCCGCATCGCTGCTCCTACTGCATGAAGACGTTTACGCGCAAGGAGCATCTGGTGAATCATATACGCCAGCACACGGGCGAATCGCCGCACAAGTGCACATACTGCACCAAGACGTTTACGCGCAAGGAGCACCTCACGAATCATGTGCGACAGCACACGGGCGATTCGCCGCATCGTTGCAGCTACTGCAAGAAGACCTTCACCCGCAAGGAGCATTTGACGAATCATGTACGCCTGCACACTGGAGATTCGCCGCACAAATGCGAATACTGCCAGAAGACGTTCACGCGCAAGGAGCATCTCAATAACCATATGCGCCAGCACTCGAGCGACAATCCCCATTGTTGCAATGTGTGCAACAAGCCCTTCACACGCAAGGAGCATTTGATTAATCACATGTCCCGTTGCCACACCGGCGATCGTCCTTTCACCTGCGAGACATGCGGTAAATCGTTCCCTCTCAAGGGTAATCTGCTGTTCCATCAGCGCAGCCACACCAAGGGCCAGGAGTGCGAGCGTCCGTTTGCCTGCGAGAAGTGCCCCAAGAATTTCATATGCAAAGGTCACTTGGTCTCGCACATGCGCTCCCATTCGGGCGAGAAACCGCACGCGTGCACACTGTGCAGCAAGGCTTTCGTCGAGCGCGGCAATTTGAAGCGCCACATGAAGATGAATCACCCGGATGCTATGATGCCGCCACCACCCgtgcatccgcatccgcaaaTACCGGCTGGTGTGCTGACCCAAGTCAAGCAGGAAGTGAAACCGATCATAA
- Protein Sequence
- MQHVSAASSAPSVVSAPVVTTGGGTTITLGGPPPLPGSKSDHKEDGGKPPHGIEMYKVNIEDISQLFTYHEVFGKIHGDVVNHVAAVHGSQLPPPQLPPPPPLPPQTTHSASAAAAAAAASTNNAAVAAVMASANAAAAAAAAASAAATAQQQQQQQQAPATSTNAGSQQGSATVTTTSSGSNGGNGGQNNNNNNNNNNNNSTTTTTGELLMPKMEGGIHGVDGQSSVALAPDGTPIATGTHVCDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTRHGKIHIGGPMFTCIVCFNVFANNTSLERHMKRHSTDKPFACTICQKTFARKEHLDNHFRSHTGETPFRCQYCAKTFTRKEHMVNHVRKHTGETPHRCDICKKSFTRKEHYVNHYMWHTGQTPHQCDVCGKKYTRKEHLANHMRSHTNETPFRCEICGKSFSRKEHFTNHILWHTGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCSYCMKTFTRKEHLVNHIRQHTGESPHKCTYCTKTFTRKEHLTNHVRQHTGDSPHRCSYCKKTFTRKEHLTNHVRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNPHCCNVCNKPFTRKEHLINHMSRCHTGDRPFTCETCGKSFPLKGNLLFHQRSHTKGQECERPFACEKCPKNFICKGHLVSHMRSHSGEKPHACTLCSKAFVERGNLKRHMKMNHPDAMMPPPPVHPHPQIPAGVLTQVKQEVKPII
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00529689;
- 90% Identity
- iTF_00588971;
- 80% Identity
- -