Drob025976.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila robusta
Gene Symbol
-
Assembly
GCA_004143805.1
Location
SCDV01000098.1:75628-82406[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 17 1.5e-05 0.0018 19.2 2.1 1 23 234 256 234 256 0.97
2 17 4.8e-06 0.00061 20.7 0.4 1 23 262 284 262 284 0.97
3 17 0.00071 0.089 13.9 0.9 1 23 290 312 290 312 0.95
4 17 1e-05 0.0013 19.7 3.1 1 23 318 340 318 340 0.97
5 17 2.3e-05 0.0029 18.5 4.7 1 23 346 368 346 368 0.99
6 17 4.2e-05 0.0053 17.7 5.7 1 23 374 396 374 396 0.97
7 17 2.1e-07 2.6e-05 25.0 4.3 1 23 402 424 402 424 0.98
8 17 7.4e-08 9.3e-06 26.4 2.4 1 23 430 452 430 452 0.97
9 17 4.3e-05 0.0055 17.7 6.7 1 23 459 481 459 481 0.97
10 17 7.6e-05 0.0095 16.9 6.5 1 23 487 509 487 509 0.98
11 17 4.9e-06 0.00061 20.7 8.1 1 23 515 537 515 537 0.98
12 17 4e-06 0.0005 20.9 7.6 1 23 543 565 543 565 0.97
13 17 4.5e-07 5.6e-05 23.9 7.7 1 23 571 593 571 593 0.98
14 17 0.00014 0.017 16.1 9.5 1 23 599 622 599 622 0.95
15 17 4.9e-05 0.0062 17.5 0.9 1 23 628 650 628 650 0.98
16 17 0.00054 0.068 14.2 3.4 1 23 660 682 660 682 0.97
17 17 6.1e-06 0.00077 20.4 1.6 1 23 688 711 688 711 0.96

Sequence Information

Coding Sequence
ATGCAGCACGTGAGCGCTGCCAGTTCGGCACCTTCGGTGGTTTCAGCACCGGTGGTGACCACTGGCGGTGGCACCACCATCACTTTGGGCGGACCGCCGCCATTACCCAATATTAAATCGGATCATAAAGAGGACGGCGGCAAGCCGCCGCACGGCATTGAAATGTATAAAGTGAACATTGAGGATATTTCACAGTTATTTACGTATCACGAGGTCTTTGGCAAAATCCATGGCGATGTGGTTAACCACGTTGCGGCGGTGCATGGCAGCCAGCTGCCACCGCCGCAgttgccaccgccgccgccactaCCGCCACAGACGACGCATTCGGCtagcgcagctgcagcagcagcggcggcgtcaTCAAATAACGCAGCCGTCGCTGCTGTAATGGCTACGGCCAATGCAGCAGCCGCGGCTGCAGTGGCCGCTTCGGCAGCGGCCACggcccaacagcaacagcagcaacaaccactgcaacaacaagcccCAGCGACAAGCACGAATGCTGGAACCCAGCAGGGCAGCGCCACAGTGACCACGACTAGCTCCGGCAGCAACGGGGGGAATGGGGGGAACAATTCGACAACTTCGACGGGTGAGTTGCTAATGCCGAAAATGGAGGGCGGCATTCATGGCGTCGATGGGCAGTCGAGCGTTGCGTTGGCGCCGGATGGCACGCCCATAGCGACTGGTACGCATGTTTGCGACATTTGTGGCAAGATGTTCCAGTTTCGTTATCAGCTAATTGTGCACCGTCGCTACCACAGCGAGCGCAAGCCGTTTATGTGTCAGGTGTGCGGTCAGGGCTTTACCACATCGCAGGATTTGACCCGTCATGGCAAGATCCACATTGGCGGTCCAATGTTCACCTGTATTGTGTGCTTCAACGTGTTTGCCAATAACACGAGTCTGGAGCGCCATATGAAACGGCATTCAACGGACAAGCCATTCGCCTGCACCATTTGCCAAAAGACTTTCGCACGCAAAGAGCATCTGGACAATCATTTTCGTTCGCATACGGGCGAAACGCCGTTCCGTTGCCAGTACTGCGCCAAGACGTTTACGCGCAAGGAGCACATGGTCAATCATGTGCGCAAACACACGGGTGAGACGCCACATCGTTGCGATATTTGTAAGAAGTCCTTCACGCGCAAGGAACACTATGTTAACCACTACATGTGGCACACTGGTCAAACACCGCACCAGTGCGATGTCTGCGGCAAGAAATACACGCGCAAGGAGCACCTAGCCAACCATATGCGCTCCCACACCAACGAGACGCCGTTCCGTTGCGAAATCTGCGGCAAGAGCTTTAGCCGTAAGGAGCACTTCACCAATCACATACTCTGGCATACAGCAGGTGAGACGCCGCATCGGTGCGACTTCTGCTCCAAGACGTTTACACGCAAGGAGCATTTGTTAAATCACGTGCGCCAGCACACGGGAGAGTCGCCGCATCGCTGCTCCTACTGCATGAAGACGTTCACGCGCAAGGAGCATCTGGTGAACCATATACGCCAGCACACGGGCGAATCGCCGCACAAGTGCACATACTGCACCAAGACGTTTACGCGCAAGGAGCACCTCACGAATCATGTGCGACAGCACACGGGCGATTCGCCGCACCGTTGCAGCTACTGCAAGAAGACGTTCACCCGCAAGGAGCATCTGACGAATCATGTTCGCCTCCACACTGGGGATTCGCCGCACAAATGCGAATACTGCCAGAAGACGTTCACGCGCAAGGAGCATCTCAATAATCATATGCGCCAGCACTCGAGCGACAATCCACATTGTTGCAACGTGTGCAACAAGCCGTTCACGCGCAAAGAACATCTGATCAATCACATGTCGCGATGCCACACCGGCGATCGTCCCTTCACCTGCGAGACGTGCGGCAAATCGTTTCCCCTCAAAGGCAACCTGCTGTTCCATCAGCGCAGCCACACCAAGGGCCAGGAGTGCGAGCGTCCGTTTGCCTGCGAGAAGTGCCCCAAGAATTTCATATGCAAAGGTCACTTGGTCTCGCACATGCGCTCCCATTCGGGCGAGAAACCGCACGCGTGCACACTGTGCAGCAAGGCTTTCGTCGAGCGCGGCAATTTGAAGCGCCACATGAAGATGAACCACCCGGATGCAATGATGCCACCACCACCCgtgcatccgcatccgcaaaTACCGGCTGGTGTGCTGACCCAAGTCAAGCAGGAAGTGAAACCGATCATAAGTGAGTCGGACACAGAACACCCGAACAAAGACACGCAAATGTGTCTGCCTGCGCCCGTTCAATCGCCAAACTGA
Protein Sequence
MQHVSAASSAPSVVSAPVVTTGGGTTITLGGPPPLPNIKSDHKEDGGKPPHGIEMYKVNIEDISQLFTYHEVFGKIHGDVVNHVAAVHGSQLPPPQLPPPPPLPPQTTHSASAAAAAAAASSNNAAVAAVMATANAAAAAAVAASAAATAQQQQQQQPLQQQAPATSTNAGTQQGSATVTTTSSGSNGGNGGNNSTTSTGELLMPKMEGGIHGVDGQSSVALAPDGTPIATGTHVCDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTRHGKIHIGGPMFTCIVCFNVFANNTSLERHMKRHSTDKPFACTICQKTFARKEHLDNHFRSHTGETPFRCQYCAKTFTRKEHMVNHVRKHTGETPHRCDICKKSFTRKEHYVNHYMWHTGQTPHQCDVCGKKYTRKEHLANHMRSHTNETPFRCEICGKSFSRKEHFTNHILWHTAGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCSYCMKTFTRKEHLVNHIRQHTGESPHKCTYCTKTFTRKEHLTNHVRQHTGDSPHRCSYCKKTFTRKEHLTNHVRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNPHCCNVCNKPFTRKEHLINHMSRCHTGDRPFTCETCGKSFPLKGNLLFHQRSHTKGQECERPFACEKCPKNFICKGHLVSHMRSHSGEKPHACTLCSKAFVERGNLKRHMKMNHPDAMMPPPPVHPHPQIPAGVLTQVKQEVKPIISESDTEHPNKDTQMCLPAPVQSPN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00529689;
90% Identity
iTF_00617035;
80% Identity
-