Basic Information

Insect: Drosophila vallismaia
Gene Symbol: egg
Assembly: GCA_035047325.1
Location: JAWNPU010000066.1:22663019-22667175[+]

Transcription Factor Domain

TF Family: MBD
Domain: MBD domain
PFAM: PF01429
TF Group: Unclassified Structure
Description: The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 3.8e-14 9.5e-11 41.3 0.0 5 75 796 859 793 861 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	3.8e-14	9.5e-11	41.3	0.0	5	75	796	859	793	861	0.91

Sequence Information

Coding Sequence: ATGGCATCCGATTCAGAAGCCATGGATTGTGCAGAGGTCACAGAACTCGCAGGAGTGGATATCCAAGAAGCGGTGGCATCAATTATGGAGGAGAAAGATGCCGGTTCGCCGGGTACTGCAGAAAAAATTAATGATGAACCCACGGCGCTCGATGAAAAGGGTGAGGACAATGTGGAGATGGCGGACTTGACGCTTGACCAACCTCATGAGCAAGCAGGGGATCCTGCAGCCGAAACAATGACCGAAAAACTCGAGGCTGAAGTGGCCCGAATTCCAGCGGTAGAGATCGATGCAAGGATAGATGAAGCGCTTGTTCCTGTTGAGATCGACTCAGATAGCAGCGTAGAGGTAATAGATTGTCCAATCAAATCTCCTTCGATTCAGCTTGGTGAGAAATACAAGGACGAAGCCGAATATTTGCTAGCAAATGACCTCGTTCCGGCTTCTAAGGACATCAAGAAGGATGGGTGCGAAGTGTTAGACAGTAGCATTGAACTTATCCGCAGTCCCACCTCCGAAGGATCTGCTGTCAAAGAGGACGATATTGAAAAGAAGAGACCCTCCTCTCCAAATGAGACTGTTGAATCCTTAGTTCCCGAAAACAATCAGTTTGGGCTTGAAGTCGAGCTGAGAAAGAAGGTAGCTCAGGACACAATTGACTTGCAACAGGATACCGTCACATGGAATGGGGATATCTTTTATGGCAAAGATTGTGTGAACTGCAACTGCAAGCGACTCCACAAGCAGTTTGTGCTGGCAAATATGGCCACCTTAAGCTTCTACAAAGTTCCCAGGAAGATATCCAAGCAGCAGTTCGTCTGCACAGGCTGCAGCGATGCAGCCATGGACATGTATGAGcAATTCGCAGGTCACCTCATGGCCCACCAACCATTATTGCTAAAAGAATTCCATGAAGATCATGCCGAATTTGTAGCTTTGGATAGCAGCGATGAAGAAGAGGATGATAAAACACAAGACGaaaaacCAGAATTTTCGAAAAACGATCTAAAACTGATTGAAAACGAATTGGAGGATGCCATCACAAGTGTACTCAACCGGGTGAGGTTTCAGGACCAGCTTAACTGGTCCAAGTCAATCCTGGTTGCCAAGACAGAGCGTTTGGAGCGACAGTTTGCAATGGCCGATAAGGAATTCGAAATGGTGCAGAGCACCGCCGACAAAATGCATTGGGCTCTTTATAATTCCTGCACTGTGGTTCACAAGCACTTGCCGCCCCTGGATCTTCAACACAATATAGCCGACTATACGCAAGTACCTCCAGCCGGAGAAATCGTGCGTCCACCCATCCAGATTGGTGAGACATACTACGCTGTTAAGAACAAGGCCATAGCTAGTTGGGTGTCTGTAAAAGTGATTGAGTTCACGGAAAGCACGGCTATTGGTGGGAATATGATGAAAAGCTACAAGATCAAGTACCTGAATACTCCATACCAGATGATAAAAACAGTGACGGCCAAGCACTTGGCTTACTTTGAGCCACCGCCAGTGCGCCTTACGATTGGCACCCGAGTAATTGCTTACTTTGACGGCACTACTCTGAATCGGGGAAAGGACAAGGGTGTTGTACAAAGTGCTTTCTATCCGGGTATTATTGCTGAGCCGTTGAAGCAGGCCAATCGCTTTCGCTACCTTATATTCTATGATGACGGCTATACGCAGTATGTGCTGCATCGCGATGTCCGTCTGGTGTGTCAGGCTTCCGAAAAGGTTTGGGAGGATGTGCACCCCGCATCTCGCGACTTCATACAGAAGTACGTGGAAAAATATTCGGTGGATCGGCCTATGGTGCAGTGCACTCGCGGCCAAAGCATGAACACCGAGTCAAATGGCACCTGGCTTTACGCGCGCGTCATTGACATTGACTGCAGCCTGGTACTGATGCACTTTGAGGCAGAAAAAAACCACACGGAGTGGATATACAGGGGATCCCTAAGATTAGGTCCGGTATTTAAGGAGACTCAGAATGCCATGAGCAGCGCAAACGCGCACCATGCACGTGTGCCAAGGCGCACAGAACCTTTCATTCGCTACACCAAGGAGATGGAATCGAGCAACATGCAGGTAAACCAAAAAATGAGGTCCATTGCGCGCAAAAGCAGCTCCGCCTCCCAAGGCGCAGGTGCCTCATCAGCATCGTGCTCTTCAGCAAATACTTCTGCCGCCGGCCGCAATGAGGCAGAAAATGCTAGCCGCGGGCCGGTCAAACATTTAAACAATTCAACCATCTACGTCGACGACGAGAATCGCCCAAAGGGTCATGTAGTCTATTTTACGGCAAAGCGCAACTTGCCGCCAAAGATTTACCGCCACCACGAGTGCAACCCgaattgtttattcaagatcATTCACCGCCTTGACAGCTACAGCCCACTTGCTAAACCTCTGCTATCCGGTTGGGAGCGCTTGGTGATGCGCCAGAAGACTAAAAAGAACGTTGTCTACAGGGGACCCTGTGGCAAAAGCCTGCGAAACTTGGCAGAGGTGCACATTTATCTTCGGGCAACCGACAATGTACTGAATGTGGATAACTTTGACTTCACACCGGACTTGAGGTGCTTGGCCGAATATTCAATCGATCCCACAATTGTCAAGGAGGCAGACATATCTAAGGGTCAGGAGAAAATGGCAATCCCGTTGGTTAACTACTACGACAACTCTTTGCCACCCCCATGTACCTACGCGAAGCAGCGAATCCCCACCGAGGGTGTGCATTTAAATCTTGATGAGGAATTCCTTGTAGGTTGCGATTGTGATGACGATTGTTCGGACAAATCCAAGTGCTCCTGCTGGCAACTGACAGTGGCTGGGGTTAAATACTGCAACCCAAAGAAGCCCATTGAAGAAATTGGATATCAGTATAAACGGCTGCACGAGCACGTGCCTACCGGTATTTATGAGTGTAACTCACGTTGTAAATGCAAGAAGAACTGCCTCAATCGTGTCGTGCAATACTCACTGGAGATGAAATTGCAAGTTTTTAAGACTTCCAATCGAGGTTGGGGATTGCGATGCGTTAACGACATTCCCAAAGGCGCCTTTATTTGCATCTATGCGGGTCATCTGCTTACCGAAACGAAGGCCAACGAGGGTGGTCAGGATGCTGGCGATGAGTACTTCGCTGATTTGGACTACATTGAAGTCGCCGAACAACTTAAAGAAGGCTACGAATCAGAGGTGGAACAATCTGAGACTGAACCGGAAGAAGATAACTATCTACCGGAAACGGAAGACGATGATGACTTCCGTCCAAACAAAACCTATAAAAAGAAGAACAAGTTTCGCTCAACACGCAGTAGTAGCGGCACGGCACAAACTACTGAAGTAGATTCACAGGAGCGAGCAGTTATAAACTTTAACCCGAATGCCGATCTGGACGAGACGGTGAGAGAGAACTCGGTGCGGCGGTTATTCGGAAAGGATGAGGCTCCCTACATAATGGATGCAAAAACCACCGGAAATCTAGGACGCTACTTTAACCACTCTTGCAATCCTAACCTCTTCGTTCAAAACGTCTTTGTAGACACCCACGACCTGCGCTTTCCCTGGGTGGCCTTTTTTTCAGCATCGCACATACGCTCCGGCACTGAACTGACCTGGAACTACAACTATGAAGTGGGCGTTGTGCCCGGCAAGGTGTTATACTGCCAGTGCGGGGCCCCTAACTGCCGTATCCGTTTGCTATAA
Protein Sequence: MASDSEAMDCAEVTELAGVDIQEAVASIMEEKDAGSPGTAEKINDEPTALDEKGEDNVEMADLTLDQPHEQAGDPAAETMTEKLEAEVARIPAVEIDARIDEALVPVEIDSDSSVEVIDCPIKSPSIQLGEKYKDEAEYLLANDLVPASKDIKKDGCEVLDSSIELIRSPTSEGSAVKEDDIEKKRPSSPNETVESLVPENNQFGLEVELRKKVAQDTIDLQQDTVTWNGDIFYGKDCVNCNCKRLHKQFVLANMATLSFYKVPRKISKQQFVCTGCSDAAMDMYEQFAGHLMAHQPLLLKEFHEDHAEFVALDSSDEEEDDKTQDEKPEFSKNDLKLIENELEDAITSVLNRVRFQDQLNWSKSILVAKTERLERQFAMADKEFEMVQSTADKMHWALYNSCTVVHKHLPPLDLQHNIADYTQVPPAGEIVRPPIQIGETYYAVKNKAIASWVSVKVIEFTESTAIGGNMMKSYKIKYLNTPYQMIKTVTAKHLAYFEPPPVRLTIGTRVIAYFDGTTLNRGKDKGVVQSAFYPGIIAEPLKQANRFRYLIFYDDGYTQYVLHRDVRLVCQASEKVWEDVHPASRDFIQKYVEKYSVDRPMVQCTRGQSMNTESNGTWLYARVIDIDCSLVLMHFEAEKNHTEWIYRGSLRLGPVFKETQNAMSSANAHHARVPRRTEPFIRYTKEMESSNMQVNQKMRSIARKSSSASQGAGASSASCSSANTSAAGRNEAENASRGPVKHLNNSTIYVDDENRPKGHVVYFTAKRNLPPKIYRHHECNPNCLFKIIHRLDSYSPLAKPLLSGWERLVMRQKTKKNVVYRGPCGKSLRNLAEVHIYLRATDNVLNVDNFDFTPDLRCLAEYSIDPTIVKEADISKGQEKMAIPLVNYYDNSLPPPCTYAKQRIPTEGVHLNLDEEFLVGCDCDDDCSDKSKCSCWQLTVAGVKYCNPKKPIEEIGYQYKRLHEHVPTGIYECNSRCKCKKNCLNRVVQYSLEMKLQVFKTSNRGWGLRCVNDIPKGAFICIYAGHLLTETKANEGGQDAGDEYFADLDYIEVAEQLKEGYESEVEQSETEPEEDNYLPETEDDDDFRPNKTYKKKNKFRSTRSSSGTAQTTEVDSQERAVINFNPNADLDETVRENSVRRLFGKDEAPYIMDAKTTGNLGRYFNHSCNPNLFVQNVFVDTHDLRFPWVAFFSASHIRSGTELTWNYNYEVGVVPGKVLYCQCGAPNCRIRLL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00475923;
90% Identity: iTF_00503984;
80% Identity: -