Dtsa013127.1
Basic Information
- Insect
- Drosophila tsacasi
- Gene Symbol
- lrrfip2_1
- Assembly
- GCA_018904565.1
- Location
- JAEIHY010005543.1:1-2020[-]
Transcription Factor Domain
- TF Family
- LRRFIP
- Domain
- LRRFIP domain
- PFAM
- PF09738
- TF Group
- Unclassified Structure
- Description
- LRRFIP1 is a transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'- AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA [1]. LRRFIP2 may function as activator of the canonical Wnt signalling pathway, in association with DVL3, upstream of CTNNB1/beta-catenin [2].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 1 2.4e-118 5.4e-114 380.8 17.1 1 299 29 324 29 325 0.95
Sequence Information
- Coding Sequence
- ATGGAAAGTGCCAGCACTGGTCGCCGAAGGAACAACATGCGGGTCAACGCGGAGGATAATGCACTAGATCAAATAACGAAAGAGGCGGAGGCACGACTTGCAGCGCGTCGACAAGCTCGTGCCGAGGCCCGCGAGATCCGTATGCGAGAGCTGGAGCGACAGCAAAAGGAGCTCGAATTAACGGCTGACCGTGTATTTGACATGCAAAGCACCACTGGCGGCGGTCCAGGCGGTGGCGATACACTCCTCTCGACGCATCCCTCACGCCTTGTCTATGGCGGCCTCATAAATGTGGCCCGTGCATCGGTATCGCGGCGCAGCAGTGAGGACTCCTTGGAGGATGACGGCCGAAGTTTTCGTGACTTCAAGCATGAGCTTAAAGACGTTGAGGAACGGTTTCGCAAGGCGATGATAACGAATGCCCAGTTGGATAACGACCGTGCATCGCAGGCTTACGAAGTGAAACTGCTCAAGGATAAGTGCGAAATAATGCAGGAATCGTTTGCGCAACTGCAGCGCGAATTTAAGGAGAAAATGCGTGACTGCAATGCCCTCAAACGAAGCCTGGATCGGGCCAATCTCGAGCTGAAGCTAGTGCAAGGACAGTTGAATGAGCGGGACTTGTTAATATCGGAGCAGGGCCTTCTGATTGTGGCTGTGGAGAACGAGGATGGCAGCGATGCCAAGCGGGCTCTGGTTAGTGTTGAGAACGCCAAGCTCTTGGCGTCCGTTCAGGGTTCTTTAGATGTTAGACTTAAAAAATTCAGTGACGAAAAGAAGAGATTGCTATCCGAGGTGCACAGTCTTCACGAACAGCTTGATGAGTATAAAAGTGGAGGAATGGCTGGAGGATCTGGCAGCTTTGCACACGGTTCTCTTGGCGAAGAAGATGATTACGAGGCTCAAAGGGAGTCAAACAAAATCATTTCAGACCATAAATATAAGCTGCAAAAGGCTGAACAAGAAATCGCCAATTTACAATCGAGTTTAGCACGTTCAGAGACTCAAGTCATTCGATACAAAAGCACTGC
- Protein Sequence
- MESASTGRRRNNMRVNAEDNALDQITKEAEARLAARRQARAEAREIRMRELERQQKELELTADRVFDMQSTTGGGPGGGDTLLSTHPSRLVYGGLINVARASVSRRSSEDSLEDDGRSFRDFKHELKDVEERFRKAMITNAQLDNDRASQAYEVKLLKDKCEIMQESFAQLQREFKEKMRDCNALKRSLDRANLELKLVQGQLNERDLLISEQGLLIVAVENEDGSDAKRALVSVENAKLLASVQGSLDVRLKKFSDEKKRLLSEVHSLHEQLDEYKSGGMAGGSGSFAHGSLGEEDDYEAQRESNKIISDHKYKLQKAEQEIANLQSSLARSETQVIRYKST
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00336724;
- 90% Identity
- iTF_00569677;
- 80% Identity
- iTF_00485127;