Dtro009126.1
Basic Information
- Insect
- Drosophila tropicalis
- Gene Symbol
- -
- Assembly
- GCA_018151085.1
- Location
- JAECWH010000848.1:15783849-15787001[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 15 2e-05 0.0016 18.9 0.7 1 23 231 254 231 254 0.96 2 15 0.00023 0.017 15.6 1.1 1 23 260 282 260 282 0.98 3 15 2.9 2.2e+02 2.7 0.4 2 23 314 335 313 335 0.91 4 15 4.9e-05 0.0038 17.7 0.9 1 23 415 438 415 438 0.97 5 15 0.17 13 6.5 0.7 1 19 445 463 445 466 0.93 6 15 9e-05 0.0069 16.8 1.4 2 23 513 534 512 534 0.96 7 15 0.0027 0.21 12.1 0.4 2 21 561 580 560 581 0.94 8 15 0.0055 0.42 11.2 2.0 1 23 639 662 639 662 0.96 9 15 0.065 5 7.8 0.5 2 23 700 722 699 722 0.95 10 15 0.00012 0.0095 16.4 1.6 2 23 761 783 760 783 0.95 11 15 0.00029 0.023 15.2 1.5 1 23 797 819 797 819 0.95 12 15 6.6e-05 0.0051 17.2 1.8 1 23 825 847 825 847 0.99 13 15 2.2e-07 1.7e-05 25.0 2.4 1 23 853 875 853 875 0.98 14 15 5.9e-05 0.0046 17.4 2.3 1 23 881 903 881 903 0.96 15 15 3.1e-05 0.0024 18.3 0.6 1 23 909 933 909 933 0.90
Sequence Information
- Coding Sequence
- ATGAAGCTGCCGATTGTCTGTCGCACCTGCGACAGTGCTAAACTCACGGACAAGCTGTATAATCTAGACACGCCTAGCAAAGAGTATCCGGAAAAGTTGCTTTCCGAAATCCTCGGTGAATTAATAAATATTGATCTAAAACTGCCTATGTCCAGTGACCAGAAGTTGCCGCAATCGTTGTGTCAATCTTGTTTAAAGAGATTAACGACTTCCTATGACTATATGAAACAAGCTTTGGCCGCTAACTTTTTGCTGATGCGGCAGCTTCAAGATTGCTTGCAGGAGTCGCCAATGGAGCTATGTGCCGAGCAACATGTGGAGGTTAAAATGGAAACTGAAGGGGATGAGAGTGATAGGGAAAACGGAGAGACTGGGAAGATAACATGCACAGAATTGCCCAATCTAGAAGAGTCTGATGCTATTGCTGATGATGGTGAGGGGGATACTAAAAGACTAATTGATCCCTTGACGATGTTAGATCCGACGGCAGTAAAAAAGGAAAATGACATACAACATACTAACATAGAAGAGGAGGAGGATAAATTGGTTAATGCTAATTTTAACGATGATGGGTTCGACGATTCCGACGACGATGAGGATGAAGACTCCCTTGACAATATTCCTCTGCAACAACGAGTTTTAAAATGGAAAAAAAACCGAAATACTCTCAAGTTGACAAGACGGCGACCTTTTGAATGTAGTGAATGTCCGAAAAGTTTCATCCGAGGCGAATCCTTAAAGAAGCATAAGTCTAGAATCCATCAATCATCTGGCCTCTTTTCTTGCTCTCTTTGCATTCGCAAATTTAACCGGCAAGAAAATCTGGAGTCTCATCTTAAGGTTCATAGTGAATCAAAGAGGTCATCTCATCTAAGCGAGCACAAGAAGGCCAAATCGATTGATGTTAATCTTTGCAAACCCCATGGTTACAAACTTATCGAATGCATGCTCTGTCAGAGTCAATATAACAAAATATTAGACTTACGCCGCCACTTAGAGAATCATCCAGAAATTACCACGCTGGCCAAACGGCCCAATGTAGAGTCTCTAGCCGATTTCTTTTATCCGGACTCAAAAAATATAGGGGAAGAGCAGCTAAAGCAACTCATACGTCAGGACTTAATGGCTGGCCATTTTCAGCGCTTCTATTCAATAACCAATCAATCTGGTTATGAAATCGATCTGGACAGTTCAGAAACCGACAGCGAAGGTGAGGCAGAGCAATCATCACAATTTCTGGAATACACTTGTGAGCTGTGCCCGCAGAGATATGCCCGAAAGTATCAGCTTTACGATCACCAGCGTCAAATTCATCCTTGGTTGGAGGCTCCCCATGTCTGTGGACGTTGTCAGGCCAGATTTGTCAGTCTTCAACTACTGCGACACCATAATGAGTCGCAGTGCCGAGTCACATACGAGAGCATCGAATTACGAATCAAACTTTTGAGTGCCCCGACTGTAAGCGTGTATTTGATAAAAAAAAAGTCTCTCACAGTCCATTTGCTCAGCGTCCATGCCGATGAATCAAAGTTGCTGCCCTGTCAGTGGTGTAGTCGCAAATTTTACCGTCGTGATTACCTAGTAAAGCACTTAAAACGACATGGATTTAAAGAGCAAGACATACCATTAGCAGAGACGTTAATACAAGCAACTTCAAAGCCCAACGGCATTAAACGGATTAGCTGTAAGATATGTAACTCTCAGTTTAAACGTGTACATGAACTACGGGCCCACATCCAACTGGAACTGGGGCTGAAGCTAACAATGTCGTCGTCGGCATCAGATCAGCCAAATATCAATTCACCGCTTAACTATTCCATAACCAATGAATCAGGATTCGAGCTGCAGTTAAGTGATTCGGAAACAGAGGACGATATGTTTATTCCGTCAGTAGGTGGTGGACATCATGTTGGCTATATGTGTGAGCTGTGTAGTATACAATGTCGACGCAAATACGAAATGATTCAGCATCAACGGGCCATGCATCGTTTCGACAAGATGCCTTATGAGTGCGAAATGTGCATCTTTAAGTGTGTTTCCAAGAGCATTATGGATCATCATCGATTGAGGCAGTGCGGTAGCCTAGATAAAAAATTATCATGTAGACAGTGCAGTTATAAATTTATGTGGCCAGAGAATCTTGAGCAGCATCTCCGTTTGCAACATGGTCAGACTTCATCTACGGCTGAGCAGCAACTTTTAATCAGCAATGACATCCTCCCAGCGAAAACAATTGCCAAGGATAAACAACCGCAGACCCAAATAGATGTCCAGCTACTGCAATGTCCACACTGTGATAGAACCTATCAAATGAAGTCTCGTCTAAACAATCACATCCGTGATGTGCATGTAAATGGCGATCGGAAGCGAAAGGAGGCGGAAAAAAGATTTCTTTGCTCATTGTGCGGACGTGAGACAAAAACAGCCGCCTGTCTAGTTACTCATATGCGACGACATACCGGCGAGAAACCCTTTAAATGCGATTTTTGTGAAATGGCCTTCCCAAGACACTCTGAAATGACAGCACATCGGCGAATGCATACAGGTGAAAAGCCATATCATTGCACTGTATGTGGCAAGGACTTCGCTCGCTCGGACAAATTAAAGAGGCACATGCTAACACACAGTGGATTAAAACCGCATGCCTGTACCTATTGTGAAAAAAGTTATCGGCAGGCGAAGGATCTAAAGTTGCATCTCCAACAGCATACTGGGGAGTGTCCCTTTATTTGCGGCACATGCGGAGAGAGGTTCATTCAAAGCAGCACACTGGAAAAACATCGAATGATGCGACGGCATTTTGATGAGGTTGAGGGAGCGTCGCTGTCATTGACACGAAATTAA
- Protein Sequence
- MKLPIVCRTCDSAKLTDKLYNLDTPSKEYPEKLLSEILGELINIDLKLPMSSDQKLPQSLCQSCLKRLTTSYDYMKQALAANFLLMRQLQDCLQESPMELCAEQHVEVKMETEGDESDRENGETGKITCTELPNLEESDAIADDGEGDTKRLIDPLTMLDPTAVKKENDIQHTNIEEEEDKLVNANFNDDGFDDSDDDEDEDSLDNIPLQQRVLKWKKNRNTLKLTRRRPFECSECPKSFIRGESLKKHKSRIHQSSGLFSCSLCIRKFNRQENLESHLKVHSESKRSSHLSEHKKAKSIDVNLCKPHGYKLIECMLCQSQYNKILDLRRHLENHPEITTLAKRPNVESLADFFYPDSKNIGEEQLKQLIRQDLMAGHFQRFYSITNQSGYEIDLDSSETDSEGEAEQSSQFLEYTCELCPQRYARKYQLYDHQRQIHPWLEAPHVCGRCQARFVSLQLLRHHNESQCRVTYESIELRIKLLSAPTVSVYLIKKKSLTVHLLSVHADESKLLPCQWCSRKFYRRDYLVKHLKRHGFKEQDIPLAETLIQATSKPNGIKRISCKICNSQFKRVHELRAHIQLELGLKLTMSSSASDQPNINSPLNYSITNESGFELQLSDSETEDDMFIPSVGGGHHVGYMCELCSIQCRRKYEMIQHQRAMHRFDKMPYECEMCIFKCVSKSIMDHHRLRQCGSLDKKLSCRQCSYKFMWPENLEQHLRLQHGQTSSTAEQQLLISNDILPAKTIAKDKQPQTQIDVQLLQCPHCDRTYQMKSRLNNHIRDVHVNGDRKRKEAEKRFLCSLCGRETKTAACLVTHMRRHTGEKPFKCDFCEMAFPRHSEMTAHRRMHTGEKPYHCTVCGKDFARSDKLKRHMLTHSGLKPHACTYCEKSYRQAKDLKLHLQQHTGECPFICGTCGERFIQSSTLEKHRMMRRHFDEVEGASLSLTRN
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00503417;
- 90% Identity
- iTF_00571316; iTF_00523845; iTF_00618570; iTF_00503417;
- 80% Identity
- -