Dequ019037.1
Basic Information
- Insect
- Drosophila equinoxialis
- Gene Symbol
- -
- Assembly
- GCA_018150345.1
- Location
- JAECWI010000966.1:5821857-5825024[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 15 2.7 2.2e+02 2.7 0.4 2 23 246 267 245 267 0.91 2 15 4.2e-05 0.0034 17.9 0.7 1 23 347 370 347 370 0.97 3 15 0.16 13 6.6 0.7 1 19 377 395 377 398 0.93 4 15 0.032 2.5 8.8 3.8 1 23 407 429 407 429 0.95 5 15 4.4e-06 0.00035 21.0 0.4 1 23 436 459 436 459 0.97 6 15 8.5e-05 0.0068 16.9 1.4 2 23 467 488 466 488 0.96 7 15 0.0039 0.31 11.7 0.6 2 21 515 534 514 535 0.94 8 15 0.0052 0.41 11.3 2.0 1 23 593 616 593 616 0.96 9 15 0.012 0.92 10.2 0.3 1 23 653 676 653 676 0.96 10 15 0.00012 0.0093 16.5 1.6 2 23 715 737 714 737 0.95 11 15 0.00028 0.022 15.3 1.5 1 23 751 773 751 773 0.95 12 15 6.3e-05 0.005 17.3 1.8 1 23 779 801 779 801 0.99 13 15 2.1e-07 1.7e-05 25.1 2.4 1 23 807 829 807 829 0.98 14 15 5.6e-05 0.0045 17.5 2.3 1 23 835 857 835 857 0.96 15 15 2.9e-05 0.0023 18.4 0.6 1 23 863 887 863 887 0.90
Sequence Information
- Coding Sequence
- ATGAAGCTACCGATTGTCTGTCGTACCTGCGACAGTGCTAAAGACACCGACAAGCTGTATAATCTAGACACGCCGAGCAAAGAATATCCGGAAAAATTGCTGTCCGAAATCCTCGGTGAATTAATAAATATTGATCTAAAGCTGCATATGTCCAGTGATCAAAAGTTGCCGCAATCGTTGTGTCAATCTTGTTTAAAGAGATTAACGGCTTCCTATGACTATATGAAACAAGCCTTGTCCGCTAACTTTTTGCTGATGCGGCAGCTCCAAGATTGCTTGCAGGAGTCGCCAATGGAGCTATGTGCCGAGCAACATGTGGAGGTTAAAATGGAAACTGAAGGGGATGAGAGTGATAGGGAAAACGGAGAGACTGGGAAGATAACCTGTACTGAATTGCCTAATCTAGAAGAATCTGATGCTATTGGTGGTGATGCTGATGGGGATACCAAGAGACTAATTGATCCCTTAACTATGTTGGATCCGACGGCAGTGAAAAAGGAAAATGACATACAACAATCCCACATAGAAGAGGAGGAGGATGAATTAGTTAATGCTAATTGTAACGATGATCGGTTCGATGAATCCGACGACGATGACGATGAAGACTCCCTTGATAATATTCCTCTGCAACAACGGGTTCATAGTGAATCAAAGAGATCATCGCATCTTAGCGAGCACAAGAAGGCCAAATCGATTGATGTCAATCTTTGCAAACCCCATGGTTATAAACTTATTGAATGCATGCTTTGTCAGAGTCAATATAACAAAATATTAGACTTACGCCGTCATTTAGAGAATCATCCAGAAATTACTACGCTGGCCAAACGGCCCAACGTAGAGTCTCTAGCCGATTTCTTTTATCCAGACTCAAAAAATATTGGAGAAGAGCAGCTAAAGCAACTCATAAGTCAGGACTTAATGGCTGGCCATTTTCAGCGCTTCTATTCAATTACGAATCAATCTGGTTATGAAATCGATTTGGACAGTTCAGAAACCGATAGCGAAGGTGAGGCAGAGCAAGAATCACAATATCTGGAATACACTTGTGAGCTGTGCCCGCAGAGATATGCGCGAAAATATCAGCTTTACGATCACCAGCGTCTAATTCATCCCTGGTTGGAGGCTCCACATGTCTGTGGTCGTTGTCAGGCCAGATTTGTCAGTCTTCAACTACTGCGACACCATAATGAGTCACAGTGCCGTAATGCCCAGAAACGTTTTTTGTGCTACAAATGTCCGTTGCGATTTCGATGGAAACATAATTTCAGGAGTCACATTCGGGAGCATCGAATTACGAATCAAACTTTTGAGTGTCCCGACTGTAAGCGTGTATTTGACAAAAAAAAGTCTCTCACGGTCCATTTACTCAGCGTCCATGCCGATGAGTCAAAGTTGCTGCCCTGCCAGTGGTGTAGTCGCAAATTCTACCGCCGTGATTACCTAGTTAAGCATTTAAAACGACATGGATTTAAAGAGCAAGACATACCGTTAGCAGAGACTTTAATACAAGCCACCTCAAAGCCCAACGGCACTAAACGGATAAGCTGCAAGATATGTAACTCTCAGTTTAAACGTGTACATGAACTACGAACCCACATCCAACTTGAACTGGGGCTGAAGCTAACGATGTCGTCGTCGGCATCAGAACAGCCAAATATCAATTCACCCCTAAACTATTCCATAACCAATGAATCAGGATTCGAGCTGCAGTTAAGTGATTCGGAAACAGAGGACGATATGTTAATGCCGGCAGTAGGTGGTGGACACAATGTTGGCTATATGTGTGAGCTGTGTAGTATACAATGTCGACGCAAATACGAAATGATTCAGCATCAACGGGCTATGCATCGGTTCGACAAGATGCCTTACGAGTGCGAAATGTGCATCTTTAAGTGTGTTTCCAAGAGCATTATGGAGCATCATCGATTGGGACAATGCGGTAACTTAAATAAAAAATTTTCATGTGGACAGTGCAGCTATAGGTTTATGTGGCCAGAGAACCTTGAGCAGCATCTCCGTTTGCAACATGGACAGACTCAATTTACGGCTGAGCAGCAGCTTTTAATGAGCAATGACATCCCTTCGGCAAAAACAATTGCCAAGGAGAAACAACCGCAGACGCAAATAGATGTCCAGGTACTTCAATGTCCACACTGTGATAGAACCTATCAAATGAAGTCTCGTCTAAACAATCACATCCGTGATGTGCACGTAAATGGCGATCGGAAACGAAAGGAGGCGGAAAAAAGATTTCTTTGCTCACTGTGCGGACGTGAGACAAAAACTGCCGCTTGTCTAGTTACTCATATGCGACGACATACTGGAGAGAAACCCTTTAAATGCGATTTTTGTGAAATGGCGTTCCCCCGACACTCGGAAATGACAGCACATCGCCGAATGCATACAGGTGAAAAACCATACCATTGCACGGTATGTGGCAAGGACTTTGCTCGCTCGGATAAATTAAAGAGACACATGCTAACACACAGTGGATTGAAACCGCATGCCTGTACCTATTGTGAAAAAAGTTATCGGCAGGCGAAGGATCTAAAGTTACATCTCCAACAGCATACTGGGGAGTGCCCCTTCATTTGCGGCACATGCGGAGAGAGGTTCATCCAAAGCAGCACACTGGAAAAGCACCGAATGATGCGACGGCATTTTGACGAGGTTGAGGGGGCGTCGATGTCATTGACACGAAATTGA
- Protein Sequence
- MKLPIVCRTCDSAKDTDKLYNLDTPSKEYPEKLLSEILGELINIDLKLHMSSDQKLPQSLCQSCLKRLTASYDYMKQALSANFLLMRQLQDCLQESPMELCAEQHVEVKMETEGDESDRENGETGKITCTELPNLEESDAIGGDADGDTKRLIDPLTMLDPTAVKKENDIQQSHIEEEEDELVNANCNDDRFDESDDDDDEDSLDNIPLQQRVHSESKRSSHLSEHKKAKSIDVNLCKPHGYKLIECMLCQSQYNKILDLRRHLENHPEITTLAKRPNVESLADFFYPDSKNIGEEQLKQLISQDLMAGHFQRFYSITNQSGYEIDLDSSETDSEGEAEQESQYLEYTCELCPQRYARKYQLYDHQRLIHPWLEAPHVCGRCQARFVSLQLLRHHNESQCRNAQKRFLCYKCPLRFRWKHNFRSHIREHRITNQTFECPDCKRVFDKKKSLTVHLLSVHADESKLLPCQWCSRKFYRRDYLVKHLKRHGFKEQDIPLAETLIQATSKPNGTKRISCKICNSQFKRVHELRTHIQLELGLKLTMSSSASEQPNINSPLNYSITNESGFELQLSDSETEDDMLMPAVGGGHNVGYMCELCSIQCRRKYEMIQHQRAMHRFDKMPYECEMCIFKCVSKSIMEHHRLGQCGNLNKKFSCGQCSYRFMWPENLEQHLRLQHGQTQFTAEQQLLMSNDIPSAKTIAKEKQPQTQIDVQVLQCPHCDRTYQMKSRLNNHIRDVHVNGDRKRKEAEKRFLCSLCGRETKTAACLVTHMRRHTGEKPFKCDFCEMAFPRHSEMTAHRRMHTGEKPYHCTVCGKDFARSDKLKRHMLTHSGLKPHACTYCEKSYRQAKDLKLHLQQHTGECPFICGTCGERFIQSSTLEKHRMMRRHFDEVEGASMSLTRN
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00571316; iTF_00612240; iTF_00618570;
- 90% Identity
- iTF_00612240;
- 80% Identity
- -