Basic Information

Insect: Drosophila trichaetosa
Gene Symbol: zfh1
Assembly: GCA_035043205.1
Location: JAWNNE010000640.1:621104-626151[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 2.9e-05 0.0019 18.5 1.0 1 23 152 174 152 174 0.97

2 15 0.00089 0.059 13.8 1.2 3 23 182 202 180 202 0.94

3 15 9.6e-05 0.0064 16.9 0.1 1 23 370 392 370 392 0.98

4 15 0.00033 0.022 15.2 0.9 1 23 398 420 398 420 0.98

5 15 0.00012 0.0079 16.6 2.3 1 23 452 475 452 475 0.94

6 15 0.025 1.6 9.3 1.5 1 23 522 544 522 544 0.93

7 15 0.0043 0.28 11.7 0.4 1 23 550 573 550 573 0.98

8 15 0.028 1.9 9.1 0.4 3 19 582 598 581 599 0.95

9 15 0.00017 0.011 16.1 5.6 1 23 608 630 608 630 0.97

10 15 0.044 2.9 8.5 1.2 2 23 636 657 635 657 0.96

11 15 9.8e-06 0.00065 20.0 1.0 1 23 666 688 666 688 0.98

12 15 0.0011 0.074 13.5 0.1 3 23 696 716 694 716 0.97

13 15 6e-05 0.0039 17.5 0.5 1 23 722 744 722 745 0.95

14 15 0.05 3.3 8.3 0.4 1 23 755 777 755 777 0.97

15 15 0.0039 0.26 11.8 0.5 1 23 1284 1306 1284 1306 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	2.9e-05	0.0019	18.5	1.0	1	23	152	174	152	174	0.97
2	15	0.00089	0.059	13.8	1.2	3	23	182	202	180	202	0.94
3	15	9.6e-05	0.0064	16.9	0.1	1	23	370	392	370	392	0.98
4	15	0.00033	0.022	15.2	0.9	1	23	398	420	398	420	0.98
5	15	0.00012	0.0079	16.6	2.3	1	23	452	475	452	475	0.94
6	15	0.025	1.6	9.3	1.5	1	23	522	544	522	544	0.93
7	15	0.0043	0.28	11.7	0.4	1	23	550	573	550	573	0.98
8	15	0.028	1.9	9.1	0.4	3	19	582	598	581	599	0.95
9	15	0.00017	0.011	16.1	5.6	1	23	608	630	608	630	0.97
10	15	0.044	2.9	8.5	1.2	2	23	636	657	635	657	0.96
11	15	9.8e-06	0.00065	20.0	1.0	1	23	666	688	666	688	0.98
12	15	0.0011	0.074	13.5	0.1	3	23	696	716	694	716	0.97
13	15	6e-05	0.0039	17.5	0.5	1	23	722	744	722	745	0.95
14	15	0.05	3.3	8.3	0.4	1	23	755	777	755	777	0.97
15	15	0.0039	0.26	11.8	0.5	1	23	1284	1306	1284	1306	0.98

Sequence Information

Coding Sequence: ATGAACAATCCGGACTATGGCGGCATCCAGTGGATACAGCAGGAAAGCAGCGCCGTCGCCGACGACAGCGAAACAGAGATGACAGCAGCCTATTTGGTCAACGCTGCCGCCAATGGAAGCATTTCCAACGGTGACGAGCTCGATCATATTGCAGCCGAGAATCTCATCTTTATGGCACGCGACCGCCAACTGAGCGAAATCATCGCCGCAAATGAGGCAAATGGCGGCAGCACCACAGTGCTAATCACAGAGAGAGACGGAAATAACGGAGTGGAATACGCCGAGTCCTTTGACGATGATGCCCAAGTCGTCACCGAGGAGATCATCACGGATGATTGGGTCCAGCATCAGGGCGCAGAGCGtgTGGAAATTGCAGCAGAGCAAATCGCTGGCAACGGCAGCTCCCAGGAGCTGTTGGACATGCAACAGAATGAATATATGGCGATGCGTCCATATCCCTGTGACTTTTGCAGTCGACGCTTTCGCAAGAAGGCCAGCCTCAACAATCATATGCTGGCGCATCAGAATGATCGTCCCCATCTCTGCAAACTGTGCGGGGCGCGTTTCTCGCGACGTGCGGAGCTCATCAGTCACTTCAAGGCTCATGCGGAGGCCCAGGTGGCCGCCGATGAAGAGGCAGCTGCGGCAGCCATTAAATTtgagccacaacagcagctgcaacagcaccagcagcagcagcgacaaattGATGATCATTTCTATGAGCAGGAATGGCCGCTGTATCAGGAACATGAACAGGAGCAGGTcgaggagcagctggagcagatcgaggagcagcagctgcagcagctggatcAGTTTCAGCAGCGGTTGCAACATTCGGTTGCACCACCAACCGCTGCTCGTGGACGTATCAGTCGATTGAAACTCAAGGAGGAGAGCTCCCAATATATTGTGATTGCCTCCGATAAACCGGAGGCGGACTTGCCTCAATACATGCATTGCGAGGCGAATGGCGATCAATCACttgccaccaacaacagtCAAGTCCAAACATCATCCGAtgatgttgcaactgctgctgctgctgatggggCAGAGGGGCAGGCAACGATGCGCTTTCCCGTGCTCGACGAGAGCAAACCGTTCGTCTGTCAGCAGTGTGGATTGGCCTTTGCCCGCGAGAAGGCGCTCGTCTCCCACATCAAGAATCATCGCGTGGATTCGCCTTTTGAATGCAATCAGTGCCAGGAGATGTTCTGGGACAATTACAGTCTGCAGGAGCATCAGAAGACGCATCAGTTCGAGGAGAGCAATTCGGAATATGATCCCGCATCGGCGGGCGAGGAGGATACGGCGAGTGAATCGGAAGCGGAACAGCTTTACGGTAATTTCTACTGTGGAGAATGCGGCATCTCCTTTCACCGGCAGGATTTGTTGCGGCgccacagcaaacagcagcacagTAAGCAGctggctgcaacaacagctggtggcaacaacaacaacaacagtgtggcaactgcaacagcaacggatGCAATGGGTGCCGcagatgcaactgcaactgatgccgatgctgatgaTTCCAAAGATGCGACACATTGTTGCCGCACGTGCGGCAAATCATTTCCCAGCGTACTCAAACTGCTCGCCCATGCCGAAATCCACAAACGCTTCCCGCCATTCAAATGTGTGCTGTGCGGAGTCAGCTTCTACGAGGAGCAGGCGATAAAGCGGCACCTGAACACGCGACATCCGCACGAGCTGAAGCCCAATTCgtgtgtgctgtgtggcaAGGAGTGTCGCGATCGGAAGGCGCTGATCAAACATGCATGGGATCATTCGCGAGAGAAGTGCCACTCGTGCTCCAAATGTGGCAAGAATTTCCACAACAAGGCGCGCCTGAAGCGACACATGGCATCGCATCGCGACAAGTCCGTCGTGTGCGAAGTGTGCCACGAGGAGTTCCCCGATGGACGCACTTTGTCCAATCATCGGCATTCCCACAGCACAACGTCGCCGGGCAAACTCTTTCCCTGCCACGAGTGCGGCAAGACTTTTGGGTCACGCAGCTCGCAACAGATTCATGTGCGCATCCACACGGGTGAAAGGCCCTACGGTTGTCGCTACTGCTGGAAGGCCTTCGCCGACGGTGGCACTCTCCGCAAACACGAACGCATCCATACGGGCGAGAAGCCCTATGCGTGCTCCGTCTGCCCGCGTGCCTTCAATCAGCGTGTCGTCTTGCGGGAACACATCCGGTCGCATCATTCCGGTCTAGATGCGGCACGTGGCACGTATCATTGCACGGTGTGCTCGGCGGATTTGAGCTCATCGAATGACCTCATCCAGCATCTCATCCAGCACAGTGATACGAACACAGCCAAACAGCGACAGCCAATTACTGGCCCACGTAAATACAAACGTCGCCGGAAACTGCAGCCGCATGAGATTGCGCACATGCGCGCCGAGCACAAGGCTGGTGGCGGCGATGGCGAGGCTGGCGAGGAGGAGGATTATGCCAGCGACTTGGACTACTGCCATCTGGATGTGGAGAATGTGGATGAACTGCTGCAGGAGGCAACGGCAGAGCCACCATCACCCGCCAAAAAAGCGAAACGCAAACGCAAAGCGCCAATTAAAACCGGTGATGAGCAAAGATTGTGGGATGAGAAATTCCCGCAGCAGGCGAGCAATGGGAATAGCGATGAGGCCTACAAGAGTTTCTTCCAGATGGACTCAATGGTCGTGGTCAATGATCAAACGTTGCAGCCCGTTGATGCTGGTGTTGCCTCGACCAAGTTGCAGCAGTCGGAGATTAAGGAGCAAACACTGAAGACGGGCAATCGCAGTAGCAAAAGAAGGGCAGGTAAAGCTgggggaggaggagcaggcgcaccaggaggaggaggagctgctgctactgctgctccaCGTCCCCGGATGATACATACGGCCAAGTCGCAGCAGACAACGGCAAGGAAATCCCGCACAAGGAGTTATGTCACACGCACCAGCAccaatgagcagcagcaggggggAGGAGCAAGTGGAGGAAGCCTCATCAAATCCCGGATTGTAGATGACTACGAGATCATCTCCCCGGCCACACAGCCACCCAATCAGATCAGCTCCAGTCCGCTGCACATCaaacaggagcaggaacatcaacagcatcatcatcagcatcagcatcatcagcagcagcaccagagaGTCCAACTGCTCTTCGATGACAGCCATCTGCTCATCGATGCGGGCCTGTTGCGTGAGAAGACTTACGAGAAATATAATCCCAGCATTGTCCAAGATCTCGAAGAGATTTTGCGTAGTCCTCCGAAGCATGAGCGGAACGATCGACGGCTGCGCTTCACCAGCGAATCGTCGACGACACCACAATTTCTGCCCggcgaggaggaggaacagCATCTCATCAAGATCGAGCCCACGTCGCCGGATCTCCGCGAAATGGTCGAGagccagcagccagcggcACTGCCCACATCTTCCTCCGCCTGCTCAACGGCAGCACGCACTTCCCGCCACCTGCGACAACTGACTGCCAATGGTTCCAGTTCCATTTCCACTGCCACATCCAGTTCCAGTGGCGCTCCAAGTACGCGAGCCGCTTCTAAGCGCAATGCCAGCAAACAGCTTTCCAAGAAACCCActtccaacagcaacaaaggcaacGCATCATCGTCTTATCTCAGCTATGGCGTCGACTCCTAtaatgtgggcgtggcaaccaGTGCCAATAGCTCCTCGGATGTCAGTTCCGgtttcttttccatttccgAGGTCGTCTCGGCGGCGGATGCAGCCGATGCAGCTGCgaaggcggcggcggcagcagccagcaaaacGGAGCGAAGAACGCGCTGCTTTGAATGCGAAATGTGCTCTTCCTATTTCCCAGATCGCGCCCAGCTGCTCgaacacatgcacatacacatctAA
Protein Sequence: MNNPDYGGIQWIQQESSAVADDSETEMTAAYLVNAAANGSISNGDELDHIAAENLIFMARDRQLSEIIAANEANGGSTTVLITERDGNNGVEYAESFDDDAQVVTEEIITDDWVQHQGAERVEIAAEQIAGNGSSQELLDMQQNEYMAMRPYPCDFCSRRFRKKASLNNHMLAHQNDRPHLCKLCGARFSRRAELISHFKAHAEAQVAADEEAAAAAIKFEPQQQLQQHQQQQRQIDDHFYEQEWPLYQEHEQEQVEEQLEQIEEQQLQQLDQFQQRLQHSVAPPTAARGRISRLKLKEESSQYIVIASDKPEADLPQYMHCEANGDQSLATNNSQVQTSSDDVATAAAADGAEGQATMRFPVLDESKPFVCQQCGLAFAREKALVSHIKNHRVDSPFECNQCQEMFWDNYSLQEHQKTHQFEESNSEYDPASAGEEDTASESEAEQLYGNFYCGECGISFHRQDLLRRHSKQQHSKQLAATTAGGNNNNNSVATATATDAMGAADATATDADADDSKDATHCCRTCGKSFPSVLKLLAHAEIHKRFPPFKCVLCGVSFYEEQAIKRHLNTRHPHELKPNSCVLCGKECRDRKALIKHAWDHSREKCHSCSKCGKNFHNKARLKRHMASHRDKSVVCEVCHEEFPDGRTLSNHRHSHSTTSPGKLFPCHECGKTFGSRSSQQIHVRIHTGERPYGCRYCWKAFADGGTLRKHERIHTGEKPYACSVCPRAFNQRVVLREHIRSHHSGLDAARGTYHCTVCSADLSSSNDLIQHLIQHSDTNTAKQRQPITGPRKYKRRRKLQPHEIAHMRAEHKAGGGDGEAGEEEDYASDLDYCHLDVENVDELLQEATAEPPSPAKKAKRKRKAPIKTGDEQRLWDEKFPQQASNGNSDEAYKSFFQMDSMVVVNDQTLQPVDAGVASTKLQQSEIKEQTLKTGNRSSKRRAGKAGGGGAGAPGGGGAAATAAPRPRMIHTAKSQQTTARKSRTRSYVTRTSTNEQQQGGGASGGSLIKSRIVDDYEIISPATQPPNQISSSPLHIKQEQEHQQHHHQHQHHQQQHQRVQLLFDDSHLLIDAGLLREKTYEKYNPSIVQDLEEILRSPPKHERNDRRLRFTSESSTTPQFLPGEEEEQHLIKIEPTSPDLREMVESQQPAALPTSSSACSTAARTSRHLRQLTANGSSSISTATSSSSGAPSTRAASKRNASKQLSKKPTSNSNKGNASSSYLSYGVDSYNVGVATSANSSSDVSSGFFSISEVVSAADAADAAAKAAAAAASKTERRTRCFECEMCSSYFPDRAQLLEHMHIHI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00542584;
90% Identity: iTF_00499722;
80% Identity: -