Basic Information

Insect: Drosophila testacea
Gene Symbol: Hivep2
Assembly: GCA_035043265.1
Location: JAWNND010001065.1:160213-168473[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.00033 0.025 15.2 0.8 1 23 218 240 218 240 0.98

2 8 9.3e-06 0.00071 20.1 1.3 1 23 246 270 246 270 0.92

3 8 0.026 2 9.3 0.1 1 19 912 930 912 933 0.93

4 8 2.9e-06 0.00022 21.7 2.0 1 23 1661 1683 1661 1683 0.99

5 8 1.2e-05 0.00094 19.7 5.3 1 23 1689 1713 1689 1713 0.92

6 8 5.8e-05 0.0044 17.6 3.4 2 23 2191 2212 2191 2212 0.97

7 8 0.00044 0.033 14.9 1.1 1 23 2218 2242 2218 2242 0.91

8 8 0.0027 0.21 12.4 2.7 1 23 2263 2287 2263 2287 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.00033	0.025	15.2	0.8	1	23	218	240	218	240	0.98
2	8	9.3e-06	0.00071	20.1	1.3	1	23	246	270	246	270	0.92
3	8	0.026	2	9.3	0.1	1	19	912	930	912	933	0.93
4	8	2.9e-06	0.00022	21.7	2.0	1	23	1661	1683	1661	1683	0.99
5	8	1.2e-05	0.00094	19.7	5.3	1	23	1689	1713	1689	1713	0.92
6	8	5.8e-05	0.0044	17.6	3.4	2	23	2191	2212	2191	2212	0.97
7	8	0.00044	0.033	14.9	1.1	1	23	2218	2242	2218	2242	0.91
8	8	0.0027	0.21	12.4	2.7	1	23	2263	2287	2263	2287	0.92

Sequence Information

Coding Sequence: ATGACGCTACAGCATGTGGCAAGTAACACAGCATCAGTTCAAGTTgccacaacaacgacaacaggcAATGCGACGGCAACAGTTGGCGATGATGCAACcacagctgcaacaattgTCGATTggacaaatacaacaaatttgcgTTATTTGCACAAGAAATTTAAACGTTTGGCCAGCACCACTGAAGCCGAGGCAATTGATGTGGTGCGCACCACATCGTTGTCATCAAATAGCTCCATatcgccaccaccaccaacaccaacggcagcagcaccaacagcagctgcagcaacagtagcagcagcaactacaacagtgttgccaatgcCATTCGCGTTGTCATTGCTCAACGGTCAAGCGATAGCAACAAATGAATTCAGTGCCAATTTTGTAAATGaggagagcaacaacaacaacaacagcagcaaccttaacaacaacagcagcagtaaatATGTTGCTAGTGCGCCTAGAACACGCACACCGcttagcagcaacaacagcaacagtaactaTGCGAGCAATGCAACATTATCGCCAGCAACATTCGCACAGCATCAGCAATCGAcgcagccaacaacaacagccacaacaacaccagcagcagcagcattagcaacaacgccagcagcaacaactAAACCAGGACGTTATATGTGTCCCTTTTGCAATATGAGCTGTGCCAAGCCATCGGTGTTGCAGAAACACATACGTGCTCATACAAATGAACGTCCGTATCCCTGTGACACCTGTGGCATTGCCTTCAAAACGAAGAGCAATCTCTATAAGCATAAACGTTCCCGCTCCCATGCGGCTCGAATGCGAGGTTTTGATGTTCCTGCCCATGAGGTGGATGGTCTCTCCGATCAGGATGTCGATGGTGAGCTGAGCAACAGCAGTTCCGAGCTCCTAAGTGTGGAAATTCTGAGTCGTGCAGAGTCGCCCTATGATGAGCCCATGGCATCGCCAACACCATCTCCATCCACGTTGTCGGCGTCGAAGAGTGCGTACTTGCAACAACCCCCAATGCCGCAGCATATGCAACAGTTGCCACTGGGCTCGCCGGCAGCAGGAACATTGCCACCGCCAACAACAGACACATTGCACTCAGCAACAGCGCAACATCGGCAATCGATTGATTACAAGCCATATAAGCCCAAGTTTCACAATGCAGCATTTTATGCGCCTGGCAGCAGTAGCAAGGAGCAGCAAGTGCACCAGCTGCAGgtgctgcaacagcaacagcaggcattacagcagcagcagcagcagcaacaacagcagcaacaacaacaacagcaacagcaaaagttgTCGTCGCAACAAGCAACTTTGACACATCCAACACTCTCACCGAGCACACAGCTTAAGCTCAACAATCACATCAACTCACATCAGatgcaattgcagctgcaacatcagcaacaacaacaacagcagttacATGCACAGCAATCACTGCTGTTGGCAGCCAATCCGGCGGCATTAACGGGATTACCACCACCACCgacaatgccaacaaatgtCTACTATTTGGGGCAGCCGCAGTATTTTAATCCAGCTGCCGCAGCGATGCATCAACAGGCACTCGCTTTTCAGCAAATGCAGTTCCAGCAGCACTTCcagctacagcagcaacagcaacaccaacaacagcagcaacaccagcagcaacaacagcaacaccaacaacattcGCCGCTGTTGAAGGCGCCCACGCATCAACCGCAAGCACAGCCACAACAAACGCAGCAACCACAGCcattgccacaacaacaacaacagCTGGTGCGTTCAAACAGTCAACAATCGTcgataacagcagcaacaacagcagcagtgttGCCCGcccctgccacgcccacgccgACTGCCAATTTGAGCAGCTTTGCCAGCGCAAGCGGAGGCATGCAAGTGAATGTGGAGAAGGTGCAGGAGCACATCTCAAAACTGATCTCACAGAACGAGGCCATAGTGGAGAATAAGGAGATACTATTGCAGAAGAAGTATCCGAAGCAGTTGAATCGTTCTCGCAGCTTTAAcaatgccaacagcaacaatagcagcagcagcagtagcaacaacatcaccagcagcaaTGTCACACctcacatcaacaacaacagcagcagcaacaatccTCAACAGCTGGGCGAGACGAAATCGAATCTGGCACAGGCCATAGttcaaaagcagcagcaacaacagctgcaacaacaacaacagcagcagcaacagttgctgcaacagcagcaataccAAATGTacctgcaacaacagcagcaacagcaactggaaCAACCTGTAAATGGTTTATTGAAGCGTGGTAGTTATGTTGGAATTAAAGgcactgccacgcccctgACAACGCCTAATGCCAagctgcaacagttgccaccGCCGCCATCACCATTGCCATTGCAAACGTTGCAATATCGTCAGGATCCAGCAACACCTGTGCCCAAAttggagcagcaacagcagcaacaacaacaatcgacaTCTAATCACGTCCAACCATTGAATTTATCTGCTAAACCAAAGCCagtgttgctgccacaaaaagtagcagcaataacagcatcagcaacaacaacaagtattGCAGCCACGCCTATGGCAAAGGTCAATGCAACGCCAACAATGCAACAGCCAAACAATTCAATAATTAAGAATCTATTGCTGAATGCACGTGGCTTAGCTGTTCCCATTGGTGAAGGCGATGATGCCGTCTATTCATGTCCCATTTGTGCCAATGAATTTCGCAGTGCGGATGATTTGAAGTTACACAATAGCACCTATTGCCAGGATGCAAATAGCAGTGGCCCAATGAGTCCAGCCTCATCGCCAAGCAGCAAATACTTTCGCTCCAATTCCATATCATTTAGTTTACCCGAACTTAAGTCCCATATGGCAAACTCGAAGAATCCATTGTCCTTGGCCAAGTTGGCGTGGTCGCAGCTAAAGACGAAGCCAAGTAGCCTGGTGTTGAGTCGCCTCAGTGCAGCACAATCGCCAGCACGCACCTCGACCGTAACCTCAacgagcaacagcagcagtaacaccaacagtcacagcaacaacaaccattgCAACAGCAGTAgtagcagcagtagcagcaacaatactTTGCCAGTTGTCACGCCAGCAACTGTGCCGCCCAGCATTGATGCCACAAGTATTGCCCTGCGTTTTGTGGATGCACCTTTGCCCTCGCCAGGTCCACTGTTGGGCAAAACGCCTCTAGTCGACTATGCGGCACCGCGTAAAACACAAGACACTCAGGTGGTGATTACGAAAATGCACGAGGATCGACTGGAGAACATGATTATTGAGACGCCAGCAAAGCGAACAAAGCTGAGCAATGACAGCggaagtggcagcagcaacaacagcaacagcatcagctcAACAAATTCGGCCTTTGCCTTGCCAGCGTCCGTACAATTGCTCTTTGGTGCTGGCAATCAGGAGACCAACAATTATAGTGCCAAGGAGGAGCGTTTGCGTCGCTTTACCTCCTCCGGTGGCAGCATGATACCCATCTCCGAGTGTCCCGAGCTTAACAAGAGTCCCAAAATGATACGCACTCCATTGTTGTCTGGCGGAAGTTTTCAGGAGATGTCGCCACGTCTCGGCGAGACAAAGGAGCGTAAATTAAGCACGGCAAATAATGTATTCCTATTAAATGCATCCTCATCCTCTTCAACGccacaacattttcaatttccgccCATCAATTCAATAACTGCCTTCAATCCTTTGACATTGCCGCccatgagcaacaacaacaacaatattggaGAAGCCAACAAGGCAATACCCTATGTACCGGGCATACCAGGACCAGGTAGTTTGTCATTGTTGCCGCCACcgcagcaactgcaattgccagcaacaacacgtGGACGCAGTCCTAATCGCAAGCAACCAAGTCCTAATCTGTTGCTGGAAGTGCCGATTAAGGCCTTGTCACCATTTGGAGGTGTACAAAATCTGCCCAGCGAATTTAGTAGATTACCGCCGACGCCAGCACAACGTAATGCATTGCAAtggaacagcagcaacaagacagcagcagcaggagcagcagcaactgcaattgctgtAGACAAGAAGCAACCGTTTAATTTCTTGCGTATGGCAGACAATGTTAAGAGCAGCTCTTCTTCCACTTCGGAGCAAACGGTTCCAGAGGTGCGACATTTTAATTTCGATAATGTGCATAAAACGCAGGAGGCGCTGGCGCCTCTGCACGTGGACACGCCAGAGGATAgcacgacagcaacaacactgtcaacaacaacaacaacatcaacgaaTGCCAAATCGAAATTTCTGCGTCCCACCAGCCTGCCCCTTAAACCTGGTACATTTACTCCTAAACGTCATCATGGAATTACGCCAACGGCAAATACATTGCCATTGATCTCACCAGAAACGCCGCGTCCATCGAAATCATGTGTACAATTGTATTTGAATGGACATGCTTACACTTATCTGGGTTTGAAGTGCAGCACCAAGATGTTCTACTGTACAGTAAACTGTCCGCAGCCATCGTATGTGGCCGGCATGCACAAGTTGTCCATGTACagtgtgtggcaagtgtgtGAGGAGAATCAACCACATCCGTTGGGTTTCAAGCCCAGAGAAGTGATGGCTTTGTATGATTCCAGGCAAAAGATGCTTGGCAGTGGCTCCTTTATGGCCATGGCTGGACAAGGCAAGATGTCGTACACGGTGGTCAGTTCACAGCAAACAGTTAGCACCTGTTCCACAACGGTCAACGGACAAAACAAGTTCTATCAGCATCAGTTGAAACAACCACCGGCAATTGCCACACTAAGTGAGGCAAATGTGGCAGCAAAGGTAGCGAATGATGAGGAAGCAGCCAAGAAATTGGAGCCGGGACAACTGCTTGTGGGTGGCTATGAGTCGCATGAGGATTACACATATATACGGGGACGTGGACGTGGTCGTTATGTTTGTTCCGAGTGTGGCATTCGTTGCAAGAAGCCATCGATGCTCAAGAAACACATACGCACCCACACGGATGTGCGTCCCTTCACCTGTAGTCACTGCAACTTTAGCTTTAAAACAAAGGGAAATCTCACCAAGCACATGCAATCAAAGACGCACTTCAAGAAATGCATTGAGCTAGGCATTAATCCGGGTCCCATGCCGGCAGATGGTGAATTCCTCGATGTTGATGTGGAATTCGATCAACAATCTTCAACTTCTGCCGGTGGACGCACTTCCTCTATGGCGGGCGAATCGGATTCTGATGATTACAGCGATAATGAGTCCGAGAGCAGCGATACCGACGAGTCCAAGTCGCGCCTAAAGGAGCACGAGGCAGCACGTGGTCTGCTCTCGTTATCCATGACACCGCCCATACCACAAAGTGTTTCTCCCTATCCCGCCCAGCTGCAGGATACTCCTCTGCCGGCTGCCAGTCCGGCAAATAGCATTGGTTCCTCGGCAGGCAGCAGCAGTGCAGCAGGAAGCTCTCAGCCCAAGCGTCTGGTTTGTTCATTTACATCACCAAAGCCACCATTTGATTACCAGAAGCAAGAACAGTATTACTCCAATCCGGAGGAGTCAAAGCCCAAGCGAAGCGTGCCCAGCGATGAGAGCAGTGCACCCATGGATCTGACCAAGCCAAGATCAAATTCTGCTCAATTAACTGCTTCAGCAGCTGGAACTTTGCCTGTGGAGCAGTTGCTGCCCAAATCTCAAGCACAACAGATGCGTGATGTCATCTTTGGTGCTGGCAACAATGAATGTGGTGGCTTCATGAAGACACTTATTTCAGTGTCGGACAAAGTGCGAATCTCTGCTGAAATGGAGGAGCAAGCGAAGCGGGAAACCGAAGGTGATGATGTCCTTTTGCAGACCTACATCAAAGAGCAGGCATTGCATAATGCCAAAATGAAGCAGAGTCAGTTTAGTCGCAGTTATCTGGttaccagcagcagcagcagcagcactagCATtaccagcagcaccagcagcagcttgGCTAGCACACCAATTATAAGCAGCAGTCTCCATGTGCTGAACAAACAACCATTGATCATCACAGAGCTGCCCAGCATTGAGGTGCATGAGGTTAAGACACCAGAGCCAGTTGCCAATGTTGCAGATGCAACACCAGCATTAGCACCAGCAGCACATGAAGAATTGGAGGAAGCTGAAACGCAAGCGGAGCAGGAGAAATCCACACCTGTTGCTGTCAGCGTCTCCAGCTCCGTATCAGTGACTGTTTCCGTGTCCAAGTCCAGCACGGAACAGTTGCCACACAATGCCAATTTGCCAGCTGCTGTCCAGCAACCAGATGCCACAGATTTCAGTGGCGTgctcagcaacagcaacaccagtaacagcagcagcaacaacactgcTCCTGCTGCACGcactgttattgttggtgaGGAGGGCTTCAAGACAACGACCACAAGTGGTGCCTCTGAGGTGGCAGCTTCCGTTTCCGTCTCTGTTGCCTCTGCCACGTATCCAGGACGTGTGGtgccaccaccgccgccaCCAATTGCCAGCGATGCGCGTCCCACTTGCAGCATCTGCAGCAAGACCTTCCAGCGGCAACATCAGCTCACGCTGCACATGAACATTCATTATATGGAGCGCAAATTCAGGTGTGAACCTTGCAACATCTCGTTTCGCACCCAGGGACATTTGCAGAAGCATGAACGTTCCGAGGCACATAAGAATAAGGTAATGATGACGTCGACATTTGGTGTGCCAACCACATCGAATCCACGTCCATTCGAATGCACCGATTGTAAGATTGCCTTTCGCATCCATGGACATTTGGCCAAGCATTTGCGTTCCAAGACGCATGTCCAAAAGCTGGAGTGTCTGCAAAAGTTGCCGTTTGGCACCTATGCGGAGATTGAACGTGCTGGTATTAGTCTGACTGAGATCGATACCAGCGATTGTGAGAATTCGTTGATATCCCTCAAGTTGCTAGCCCAGAAGCTGCTCGAAAAGGATCCCAATAAGCTGAGTGGTTATACAACGCCATCGGGTATGTTGCAACTTAATTCAAATGCACCTGCAGCGGGTCAGGATAGCGCCTCCGAGGATGGCTTCAGTGCGGCAAACAGTGCAGCTGCCTCGGCGATTGCCTCGCTGGATAACGATAGTGCGGGCAATACGCCACAACGTGCCAGCTCCATGTCCGAGGATGAAACACTTGCCAATGGCCTCAGTCATAGTCATGGCCATAGCCTCAAGCGGCGTCTGCCCGTCAGCAGCTTtagcagcaacgacaacggcgaTGAAAGCGACAATCCCCTCGAAGGAGGAGGCGGAGGTGGAGTCGAGAAGCGTTCGAGgagcaacacaaatgaattgACGCTGCCGGTGGCAGCATCGACGGCAACGGCAAGCAACTGA
Protein Sequence: MTLQHVASNTASVQVATTTTTGNATATVGDDATTAATIVDWTNTTNLRYLHKKFKRLASTTEAEAIDVVRTTSLSSNSSISPPPPTPTAAAPTAAAATVAAATTTVLPMPFALSLLNGQAIATNEFSANFVNEESNNNNNSSNLNNNSSSKYVASAPRTRTPLSSNNSNSNYASNATLSPATFAQHQQSTQPTTTATTTPAAAALATTPAATTKPGRYMCPFCNMSCAKPSVLQKHIRAHTNERPYPCDTCGIAFKTKSNLYKHKRSRSHAARMRGFDVPAHEVDGLSDQDVDGELSNSSSELLSVEILSRAESPYDEPMASPTPSPSTLSASKSAYLQQPPMPQHMQQLPLGSPAAGTLPPPTTDTLHSATAQHRQSIDYKPYKPKFHNAAFYAPGSSSKEQQVHQLQVLQQQQQALQQQQQQQQQQQQQQQQQQKLSSQQATLTHPTLSPSTQLKLNNHINSHQMQLQLQHQQQQQQQLHAQQSLLLAANPAALTGLPPPPTMPTNVYYLGQPQYFNPAAAAMHQQALAFQQMQFQQHFQLQQQQQHQQQQQHQQQQQQHQQHSPLLKAPTHQPQAQPQQTQQPQPLPQQQQQLVRSNSQQSSITAATTAAVLPAPATPTPTANLSSFASASGGMQVNVEKVQEHISKLISQNEAIVENKEILLQKKYPKQLNRSRSFNNANSNNSSSSSSNNITSSNVTPHINNNSSSNNPQQLGETKSNLAQAIVQKQQQQQLQQQQQQQQQLLQQQQYQMYLQQQQQQQLEQPVNGLLKRGSYVGIKGTATPLTTPNAKLQQLPPPPSPLPLQTLQYRQDPATPVPKLEQQQQQQQQSTSNHVQPLNLSAKPKPVLLPQKVAAITASATTTSIAATPMAKVNATPTMQQPNNSIIKNLLLNARGLAVPIGEGDDAVYSCPICANEFRSADDLKLHNSTYCQDANSSGPMSPASSPSSKYFRSNSISFSLPELKSHMANSKNPLSLAKLAWSQLKTKPSSLVLSRLSAAQSPARTSTVTSTSNSSSNTNSHSNNNHCNSSSSSSSSNNTLPVVTPATVPPSIDATSIALRFVDAPLPSPGPLLGKTPLVDYAAPRKTQDTQVVITKMHEDRLENMIIETPAKRTKLSNDSGSGSSNNSNSISSTNSAFALPASVQLLFGAGNQETNNYSAKEERLRRFTSSGGSMIPISECPELNKSPKMIRTPLLSGGSFQEMSPRLGETKERKLSTANNVFLLNASSSSSTPQHFQFPPINSITAFNPLTLPPMSNNNNNIGEANKAIPYVPGIPGPGSLSLLPPPQQLQLPATTRGRSPNRKQPSPNLLLEVPIKALSPFGGVQNLPSEFSRLPPTPAQRNALQWNSSNKTAAAGAAATAIAVDKKQPFNFLRMADNVKSSSSSTSEQTVPEVRHFNFDNVHKTQEALAPLHVDTPEDSTTATTLSTTTTTSTNAKSKFLRPTSLPLKPGTFTPKRHHGITPTANTLPLISPETPRPSKSCVQLYLNGHAYTYLGLKCSTKMFYCTVNCPQPSYVAGMHKLSMYSVWQVCEENQPHPLGFKPREVMALYDSRQKMLGSGSFMAMAGQGKMSYTVVSSQQTVSTCSTTVNGQNKFYQHQLKQPPAIATLSEANVAAKVANDEEAAKKLEPGQLLVGGYESHEDYTYIRGRGRGRYVCSECGIRCKKPSMLKKHIRTHTDVRPFTCSHCNFSFKTKGNLTKHMQSKTHFKKCIELGINPGPMPADGEFLDVDVEFDQQSSTSAGGRTSSMAGESDSDDYSDNESESSDTDESKSRLKEHEAARGLLSLSMTPPIPQSVSPYPAQLQDTPLPAASPANSIGSSAGSSSAAGSSQPKRLVCSFTSPKPPFDYQKQEQYYSNPEESKPKRSVPSDESSAPMDLTKPRSNSAQLTASAAGTLPVEQLLPKSQAQQMRDVIFGAGNNECGGFMKTLISVSDKVRISAEMEEQAKRETEGDDVLLQTYIKEQALHNAKMKQSQFSRSYLVTSSSSSSTSITSSTSSSLASTPIISSSLHVLNKQPLIITELPSIEVHEVKTPEPVANVADATPALAPAAHEELEEAETQAEQEKSTPVAVSVSSSVSVTVSVSKSSTEQLPHNANLPAAVQQPDATDFSGVLSNSNTSNSSSNNTAPAARTVIVGEEGFKTTTTSGASEVAASVSVSVASATYPGRVVPPPPPPIASDARPTCSICSKTFQRQHQLTLHMNIHYMERKFRCEPCNISFRTQGHLQKHERSEAHKNKVMMTSTFGVPTTSNPRPFECTDCKIAFRIHGHLAKHLRSKTHVQKLECLQKLPFGTYAEIERAGISLTEIDTSDCENSLISLKLLAQKLLEKDPNKLSGYTTPSGMLQLNSNAPAAGQDSASEDGFSAANSAAASAIASLDNDSAGNTPQRASSMSEDETLANGLSHSHGHSLKRRLPVSSFSSNDNGDESDNPLEGGGGGGVEKRSRSNTNELTLPVAASTATASN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00523176;
90% Identity: iTF_00558129;
80% Identity: -