Basic Information

Insect: Drosophila neotestacea
Gene Symbol: Hivep2
Assembly: GCA_035044365.1
Location: JAWNMD010000076.1:220777-229156[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.00032 0.024 15.2 0.8 1 23 248 270 248 270 0.98

2 8 9e-06 0.00069 20.1 1.3 1 23 276 300 276 300 0.92

3 8 0.025 1.9 9.3 0.1 1 19 945 963 945 966 0.93

4 8 2.8e-06 0.00022 21.7 2.0 1 23 1692 1714 1692 1714 0.99

5 8 1.2e-05 0.00091 19.7 5.3 1 23 1720 1744 1720 1744 0.92

6 8 5.6e-05 0.0043 17.6 3.4 2 23 2198 2219 2198 2219 0.97

7 8 0.00042 0.032 14.9 1.1 1 23 2225 2249 2225 2249 0.91

8 8 0.0026 0.2 12.4 2.7 1 23 2270 2294 2270 2294 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.00032	0.024	15.2	0.8	1	23	248	270	248	270	0.98
2	8	9e-06	0.00069	20.1	1.3	1	23	276	300	276	300	0.92
3	8	0.025	1.9	9.3	0.1	1	19	945	963	945	966	0.93
4	8	2.8e-06	0.00022	21.7	2.0	1	23	1692	1714	1692	1714	0.99
5	8	1.2e-05	0.00091	19.7	5.3	1	23	1720	1744	1720	1744	0.92
6	8	5.6e-05	0.0043	17.6	3.4	2	23	2198	2219	2198	2219	0.97
7	8	0.00042	0.032	14.9	1.1	1	23	2225	2249	2225	2249	0.91
8	8	0.0026	0.2	12.4	2.7	1	23	2270	2294	2270	2294	0.92

Sequence Information

Coding Sequence: ATGACGCTACAGCATGTTGCAAGTAACACAGCATCAGTTCAAGTTgccacaacaacgacaacaagcaATGCGACGGCAACAGTTGGCGATGATGCAACcacagctgcaacaattgTCGATTggacaaatacaacaaatttgcgtTATTTGCACAAGAAATTCAAACGTTTGGCCAGCACCACTGAAGCCGAGGCAATTGATGTGGTGCGCACCACATCGTTGTCATCAAATAGCTCCATatcgccaccaccaccaacaccaacggcagcagcagcaccaacagcagcagcagcaacagtagcagcagcaactacaacagtgttgccaatgcCATTCGCGTTGTCATTGCTCAACGGTCAAGCGATAGCAACAAATGAATTCAGTGCCAATTTTGTAAATGaggagagcaacaacaacaacaacagcagcaacattaacaacaacagcagcagtaaatATGTTGCTAGTGCGCCTAGAACACGCACACCGcttagcagcaacaacagcaacagtaactaTGCCAGCAATGCTACATTATCGCCAGCAACATTCGCACAGCATCAGCAATCGAcgcagccaacaacaacagcaacaacaacaccagcagcagcaacaactgttacTGCCACAGCAACACTGCAAAtacagcaccagcaacaacaacaacaaccagcaacaactgcaacaacaacaacaaccgcaattacaacaacaccTGCCAGCACCGAGAAACCAGGACGTTATATGTGTCCCTTTTGCAATATGAGCTGTGCCAAGCCATCGGTGTTGCAGAAACACATACGTGCCCATACAAATGAACGTCCGTATCCCTGTGACACCTGTGGCATTGCCTTCAAAACGAAGAGCAATCTCTATAAGCATAAACGTTCCCGCTCCCATGCGGCACGTATGCGAGGCTTTGACGTGCCTGCCCATGAGGTGGATGGTCTCTCCGATCAGGATGTCGATGGTGAGCTGAGCAACAGCAGTTCCGAGCTCCTAAGTGTGGAAATTCTGAGTCGTGCAGAGTCGCCCTATGATGAGCCGATGGCATCGCCAACACCATCTCCATCCACGTTGTCGGCGTCGAAGAGTGCATACTTGCAACAACCACCAATGCCGCAGCATATGCAACAGTTGCCACTGGGCTCGCCGGCAGCAGGAACATTGCCACCGCCAACAGCAGACACATTGCACTCAGCAACAGCGCAACATCGGCAATCGATTGATTACAAGCCATATAAGCCCAAGTTTCACAATGCAGCATTTTATGCGCCTGGCAGCAGTAGCAAGGAGCAGCAAGTGCACCAGCTGCAggtgctgcaacagcaacagcaggcattacagcaacagcagcagcaacaacaacaacaacaacagcagcaacaacaacagcaaaagttgTCGTCGCAACAAGCAACTTTGACACATCCAACACTCTCACCGAGCACACAGCTTAAGCTCAACAATCACATCAACTCACATCAGatgcaattgcagctgcaacatcagcaacaacaacaacagcagttacACGCACAGCAATCATTGCTGTTGGCGGCAAATCCGGCGGCGTTAACGGGACTACCACCACCACCGACAATGCCAACAAATGTCTACTATTTGGGGCAGCCGCAGTATTTTAATCCAGCTGCCGCAGCGATGCATCAACAGGCGCTCGCCTTTCAGCAAATGCAGTTCCAGCAACACTtccagctgcagcagcaacagcaacaccaacaacagcagcaacaccagcaacaacaacagcaacaccaacaacattcGCCGCTGTTGAAGGCGCCCACGCATCAACCGCAAGCACAGCCACAACAAACGCAGCAACCACAGCCattgtcacaacaacaacaacaacaacagCTGGTGCGTTCAAACAGTCAGCAGTCGTcgataacagcagcaacaacagcaacagtgtTGCCTgcccctgccacgcccacgccaTCTGCCAATTTAAGCAGCTTTGCCAGTGCCAGCGGAGGCATGCAAGTGAATGTGGAGAAGGTGCAGGAGCACATCTCAAAACTGATCTCACAGAACGAGGCCATAGTGGAGAATAAGGAGATACTATTGCAGAAGAAGTATCCGAAGCAGTTGAATCGTTCTCGCAGCTTTAAcaatgccaacagcaacaatagcagcaacagtagcaacaacatcaacagcagcaatgtcACACctcacatcaacaacaacagcaacaacagcagcaacaatccTCAACAGCTGGGCGAGACGAAATCGAATCTGGCACAGGCCATAGttcaaaagcagcagcaacagcagctgcaacaacaacagcagcagcagcaacagttgctgcaacagcagcaataccAAATGTacctgcaacaacagcagcaacagcaactggaaCAACCTGTAAATGGTTTATTGAAGCGCGGCAGTTATGTTGGAATTAAAGGCACTGCCACGCCCCTGACAACGCCTAATTCCAAGCTACAACAGTTGCCACCGCCGCCATCACCATTGCCATTGCAAACGTTGCAATATCGTCAGGATCCAGCAACACCTGTGCCCAAAttggagcagcaacagcagcaacaacaacaatcgacaTCTAATCACGTCCAACCATTGAATTTATCTGCTAAACCAAAGCcagtgttgctgccacaaaaaGTAGCTGCAATAACAgcgtcagcaacaacaacaagtattGCAGCCACGCCCATGGCAAAGAGCaatgcaacaccaacaatgcAACAGCCAAACAATTCGATAATTAAGAATCTATTGCTGAATGCACGTGGCTTAGCTGTTCCCATTGGTGAAGGCGATGATGCCGTCTATTCATGTCCGATTTGTGCCAATGAATTTCGCAGTGCGGATGATTTAAAGTTGCACAATAGCACCTATTGCCAGGATGCAAACAGCAGTGGCCCAATGAGTCCAGCTTCATCGCCAAGCAGCAAATACTTTCGCTCCAATTCCATATCATTTAGTTTACCCGAACTCAAATCCCATATGGCCAACTCGAAGAATCCATTATCCTTGGCCAAGTTGGCGTGGTCGCAGCTAAAGACGAAGCCAAGTAGCCTGGTGTTGAGTCGCCTCAGTGCGGCACAATCGCCAGCACGCACCTCGACCGTAACCTCAacgagcaacagcagcagtaacaccaacagccacagcaacaacaaccattgCAACAGCagtagtagcagcagcagcagcaacaacaatactttGCCAGTTGTCACGCCAGCAACTGTGCCGCCCAGCATTGATGCCACAAGTGTTGCCCTGCGTTTTGTGGATGCACCTTTACCCTCACCAGGTCCACTGTTGGGCAAAACGCCTCTAGTCGATTATGCGGCACCGCGTAAAACACAAGACACTCAGGTGGTGATTACGAAAATGCACGAGGATCGATTGGAGAACATGATTATTGAGACGCCAGCAAAGCGAACAAAGCTGAGTAacgacagcggcagcagcaacaacagcaacagcatcagctcAACAAATTCGGCCTTTGCCTTGCCAGCGTCCGTACAATTGCTCTTTGGTGCTGGCAATCAGGAGACCAACAATTATAGTGCCAAGGAGGAGCGTTTGCGTCGCTTTACTTCCTCCGGTGGCAGCATGATACCCATCTCCGAGTGTCCCGAGCTCAACAAGAGTCCCAAAATGATACGTACTCCATTGTTGTCTGGCGGAAGTTTTCAGGAGATGTCGCCACGTCTCGGCGAGACAAAGGAGCGCAAATTAAGCACGGCAAATAATGGATTCCTATTGAAtgcatcctcatcctcatcaacGCCACAACACTTTCAATTTCCGCCCATCAATTCAATAACTGCCTTCAATCCTTTGACATTGCCGCccatgagcaacaacaacaacaatgttggaGAAGCCAACAAGGCAATACCCTATGTACCGGGTATACCAGGACCAGGTAGTTTGTCATTGTTGCCGCCACcgcaacaactgcaattgccagcaacaacacgtGGACGCAGTCCTAATCGCAAGCAACCAAGTCCTAATCTGTTGCTGGAAGTGCCAATTAAGGCCTTGTCACCATTTGGAGGTGTACAAAATCTTCCCAGCGAATTTAGTAGATTACCGCCGACGCCAGCACAACGTAATGCATTGCAAtggaacagcagcaacaagacagtagcagcagcagcagcagcagcaactgcaattgttgtAGACAAGAAGCAACCATTTAATTTTCTGCGCATGGCAGACAATGTCAAGAGCAGCTCTTCTTCCATTTCGGAGCAGACTGTTCCAGAGGTGCGGCATTTCAATTTCGATAATGTGCATAAAACGCAGGAGGCGCTGGCGCCTCTACACGTGGACACGCCGGAGGAAAgcacgacagcaacaacactggcaacaacaacatcaacgaaTGCCAAATCGAAATTTCTGCGTCCCACCAGCCTGCCCCTTAAACCTGGTACATTTACTCCTAAACGTCATCATGGAATCACACCAACGGCAAACACATTGCCATTGATCTCTCCAGAAACGCCGCGTCCATCGAAATCATGTGTACAATTGTATTTGAATGGACACGCTTACACTTATCTGGGTTTGAAGTGCAGCACCAAGATGTTCTACTGTACAGTAAACTGTCCGCAGCCATCGTATGTGGCCGGCATGCACAAGTTGTCCATGTACagtgtgtggcaagtgtgtGAGGAGAATCAACCACATCCGCTGGGTTTCAAGCCCAGGGAAGTGATGGCTTTGTATGATTCTAGGCAAAAGATGCTTGGCAGTGGCTCCTTTATGGCCATGGCTGGACAAGGCAAGATGTCCTACACGGTGGTCAGTTCACAGCAAACAGTTAGCACCTGTTCCACAACGGTCAACGGACAGAACAAGTTCTATCAGCATCAGTTGAAACAACCACCGGCAATTGCCACATTGAGTGAGGCAAATGTGGCAGCAAAGGTAGCGAATGATGAGGAAGCAGCCAAGAAATTGGAGCCGGGACAACTGCTTGTGGGTGGCTATGAGTCGCATGAGGATTACACATATATACGGGGACGTGGACGTGGTCGTTATGTGTGTTCCGAGTGTGGCATTCGTTGCAAGAAGCCATCGATGCTCAAGAAGCACATACGCACCCACACGGATGTGCGACCCTTCACCTGTAGTCACTGCAACTTTAGCTTTAAAACAAAGGGAAATCTCACCAAGCACATGCAATCAAAGACGCACTTTAAGAAATGCATTGAGCTAGGCATTAATCCGGGTCCCATGCCGGCAGATGGCGAATTCCTCGATGTTGATGTGGAATTCGATCAACAATCTTCGACTTCTGCCGGTGGACGCACTTCCTCTATGGCGGGCGAATCGGACTCTGATGATTACAGTGATAATGAGTCCGAGAGCAGCGATACCGATGAGTCCAAGTCGCGCCTGAAGGAGCACGAGGCAGCACGTGGTCTGCTCTCGTTATCCATGACGCCGCCCATACCACAAAGTGTATCTCCCTATCCCGCCCAGCTGCAGGATACTCCTCTGCCGGCTGCCAGTCCGGCAAATAGCATTGGTTCCTCGGCAGGCAGCAGCAGTGCAGCAGGAAGTTCTCAGCCCAAGCGTCTGGTTTGTTCATTTACATCACCAAAGCCACCATTTGATTACCAGAAGCAAGAACAGTATTACTCCAATCCGGAGGAGTCGAAGCCCAAGCGAAGCGTGCCCAGCGATGAGAGCAGTGCACCCATGGATCTGACCAAGCCAAGATCAACTTCTGCTCAATTAACTGCTTCAGCAGCTGGAACTTTGCCTGTGGAGCAGTTGCTGCCCAAATCCCAAGCACAACAGATGCGTGATGTCATCTTTGGTACTGGCAACAACGAAAGTGGCTTCATGAAGACACTTATTTCAGTGTCGGACAAAGTGCGCATCTCGGCTGAAATGGAGGAGCAAGCGAAGCGGGAAACCGAAGGCGATGATGTCCTTTTGCAGACTTACATCAAGGAGCAGGCATTGCATAATGCCAAAATGAAGCAGAGTCAGTTTAGTCGCAGTTATCTGGttaccagcagcagcactaGCATCACctgcagcaccagcagcagcttgGCTAGCACACCAATTATAAGCAGCAGTCTCCATGTGCTAAACAAACAACCATTGATCATCACAGAGCTGCCCAGCATTGAGGTGCATGAGGTGAAGACACCAGAGCCAGTAGCCAATGTTGCAGATGCAACACCAGCATCAGCACCAGCTGCACTTGAAGAGTTGGAGGAAGCTGAAACCCAAGCGGAGCAGGAGAAATCAACACCTGTTGCTTTGCCACACAATGCCAATTTGCCAGCTGCTGTCCAGCAACCAGATGCCACAGATTTCAGTGGCGTgctcagcaacagcaacaccagtaacagcaacagcaacaacactgcTCCTGCTGCACGcactgttattgttggtgAGGAGGGCTTCAAGACAACGACCACAAGTGGTGCCTCTGAGGTGGCAGCTGCCGTTTCCGTCTCGGTTGCCTCTGCCACGTATCCAGGACGTGTGgtgccaccaccgccgcctccAATTGCCAGCGATGCGCGTCCCACTTGCAGCATCTGCAGCAAGACCTTCCAGCGGCAACATCAGCTAACGCTGCACATGAACATTCATTATATGGAGCGCAAATTCAGGTGTGAACCTTGCAACATCTCGTTTCGCACCCAGGGACATTTGCAGAAGCATGAACGTTCCGAGGCCCATAAGAATAAGGTAATGATGACGTCGACATTTGGTGTGCCAACCACATCGAATCCACGACCATTCGAGTGTACCGATTGTAAGATTGCCTTTCGCATCCATGGACATTTGGCCAAGCATTTGCGTTCCAAGACGCATGTCCAGAAGCTGGAGTGTCTGCAAAAGTTACCGTTTGGCACCTATGCGGAAATTGAACGTGCTGGCATTAGTCTGACTGAGATCGATACCAGCGATTGTGAGAATTCGTTGATATCCCTCAAGTTGCTAGCGCAAAAGCTACTCGAAAAGGATCCCAATAAGCTGAGCGGTTATACAACGCCATCGGGTATGTTGCAACTCAATTCGAATGCACCCGCTGCGGGTCAGGATAGCGCCTCCGAGGATGGCTTCAGTGCGGCAAATAGTGCAGCTGCCTCGGCGATTGCCTCGCTGGATAACGATAGTGCGGGCAATACGCCACAACGTGCCAGCTCCATGTCCGAGGATGAAACACTTGCCAATGGCCTCAGTCATAGTCATGGCCATAGCCTAAAGCGTCGGCTGCCCGTCAGCAGCTtcagcagcaacgacaacggcgaTGAAAGCGACAATCCCCTCGAAGGAGGTGGAGTCGAGAAGCGTTCGAGGAGCAACACAAATGAATTGACGCTGCCGGTGGCAGCATCGACGGCAACGGCAAGCAACTGA
Protein Sequence: MTLQHVASNTASVQVATTTTTSNATATVGDDATTAATIVDWTNTTNLRYLHKKFKRLASTTEAEAIDVVRTTSLSSNSSISPPPPTPTAAAAPTAAAATVAAATTTVLPMPFALSLLNGQAIATNEFSANFVNEESNNNNNSSNINNNSSSKYVASAPRTRTPLSSNNSNSNYASNATLSPATFAQHQQSTQPTTTATTTPAAATTVTATATLQIQHQQQQQQPATTATTTTTAITTTPASTEKPGRYMCPFCNMSCAKPSVLQKHIRAHTNERPYPCDTCGIAFKTKSNLYKHKRSRSHAARMRGFDVPAHEVDGLSDQDVDGELSNSSSELLSVEILSRAESPYDEPMASPTPSPSTLSASKSAYLQQPPMPQHMQQLPLGSPAAGTLPPPTADTLHSATAQHRQSIDYKPYKPKFHNAAFYAPGSSSKEQQVHQLQVLQQQQQALQQQQQQQQQQQQQQQQQQKLSSQQATLTHPTLSPSTQLKLNNHINSHQMQLQLQHQQQQQQQLHAQQSLLLAANPAALTGLPPPPTMPTNVYYLGQPQYFNPAAAAMHQQALAFQQMQFQQHFQLQQQQQHQQQQQHQQQQQQHQQHSPLLKAPTHQPQAQPQQTQQPQPLSQQQQQQQLVRSNSQQSSITAATTATVLPAPATPTPSANLSSFASASGGMQVNVEKVQEHISKLISQNEAIVENKEILLQKKYPKQLNRSRSFNNANSNNSSNSSNNINSSNVTPHINNNSNNSSNNPQQLGETKSNLAQAIVQKQQQQQLQQQQQQQQQLLQQQQYQMYLQQQQQQQLEQPVNGLLKRGSYVGIKGTATPLTTPNSKLQQLPPPPSPLPLQTLQYRQDPATPVPKLEQQQQQQQQSTSNHVQPLNLSAKPKPVLLPQKVAAITASATTTSIAATPMAKSNATPTMQQPNNSIIKNLLLNARGLAVPIGEGDDAVYSCPICANEFRSADDLKLHNSTYCQDANSSGPMSPASSPSSKYFRSNSISFSLPELKSHMANSKNPLSLAKLAWSQLKTKPSSLVLSRLSAAQSPARTSTVTSTSNSSSNTNSHSNNNHCNSSSSSSSSNNNTLPVVTPATVPPSIDATSVALRFVDAPLPSPGPLLGKTPLVDYAAPRKTQDTQVVITKMHEDRLENMIIETPAKRTKLSNDSGSSNNSNSISSTNSAFALPASVQLLFGAGNQETNNYSAKEERLRRFTSSGGSMIPISECPELNKSPKMIRTPLLSGGSFQEMSPRLGETKERKLSTANNGFLLNASSSSSTPQHFQFPPINSITAFNPLTLPPMSNNNNNVGEANKAIPYVPGIPGPGSLSLLPPPQQLQLPATTRGRSPNRKQPSPNLLLEVPIKALSPFGGVQNLPSEFSRLPPTPAQRNALQWNSSNKTVAAAAAAATAIVVDKKQPFNFLRMADNVKSSSSSISEQTVPEVRHFNFDNVHKTQEALAPLHVDTPEESTTATTLATTTSTNAKSKFLRPTSLPLKPGTFTPKRHHGITPTANTLPLISPETPRPSKSCVQLYLNGHAYTYLGLKCSTKMFYCTVNCPQPSYVAGMHKLSMYSVWQVCEENQPHPLGFKPREVMALYDSRQKMLGSGSFMAMAGQGKMSYTVVSSQQTVSTCSTTVNGQNKFYQHQLKQPPAIATLSEANVAAKVANDEEAAKKLEPGQLLVGGYESHEDYTYIRGRGRGRYVCSECGIRCKKPSMLKKHIRTHTDVRPFTCSHCNFSFKTKGNLTKHMQSKTHFKKCIELGINPGPMPADGEFLDVDVEFDQQSSTSAGGRTSSMAGESDSDDYSDNESESSDTDESKSRLKEHEAARGLLSLSMTPPIPQSVSPYPAQLQDTPLPAASPANSIGSSAGSSSAAGSSQPKRLVCSFTSPKPPFDYQKQEQYYSNPEESKPKRSVPSDESSAPMDLTKPRSTSAQLTASAAGTLPVEQLLPKSQAQQMRDVIFGTGNNESGFMKTLISVSDKVRISAEMEEQAKRETEGDDVLLQTYIKEQALHNAKMKQSQFSRSYLVTSSSTSITCSTSSSLASTPIISSSLHVLNKQPLIITELPSIEVHEVKTPEPVANVADATPASAPAALEELEEAETQAEQEKSTPVALPHNANLPAAVQQPDATDFSGVLSNSNTSNSNSNNTAPAARTVIVGEEGFKTTTTSGASEVAAAVSVSVASATYPGRVVPPPPPPIASDARPTCSICSKTFQRQHQLTLHMNIHYMERKFRCEPCNISFRTQGHLQKHERSEAHKNKVMMTSTFGVPTTSNPRPFECTDCKIAFRIHGHLAKHLRSKTHVQKLECLQKLPFGTYAEIERAGISLTEIDTSDCENSLISLKLLAQKLLEKDPNKLSGYTTPSGMLQLNSNAPAAGQDSASEDGFSAANSAAASAIASLDNDSAGNTPQRASSMSEDETLANGLSHSHGHSLKRRLPVSSFSSNDNGDESDNPLEGGGVEKRSRSNTNELTLPVAASTATASN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00523176;
90% Identity: iTF_00608650; iTF_00583896;
80% Identity: -