Dtei015402.1
Basic Information
- Insect
- Drosophila teissieri
- Gene Symbol
- ftz-f1
- Assembly
- GCA_016746235.1
- Location
- CM028596.1:15383354-15421990[+]
Transcription Factor Domain
- TF Family
- SF-like
- Domain
- zf-C4|SF-like
- PFAM
- AnimalTFDB
- TF Group
- Zinc-Coordinating Group
- Description
- The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 4 0.17 1.3e+03 -1.7 4.8 60 192 50 184 27 193 0.48 2 4 2 1.6e+04 -12.1 16.0 36 152 131 275 113 292 0.44 3 4 3.2e-19 2.6e-15 56.6 0.4 1 76 479 554 479 581 0.73 4 4 5.9e-70 4.8e-66 223.7 0.3 156 409 682 928 662 929 0.93
Sequence Information
- Coding Sequence
- ATGGATACCTTCAATACGATCGATGGCAGTCAACTGGATGGAGGCATCTCCTTGAGCGGCTTGTGCGATCGCTTCTTTGTGGCCAGTCCGAATCCCCACAGCAATAGCAATATGACTCTAATGGGCACTGCGACAGCAGCAACAACAACTACCACTACCAACAACAATAATAATAACAACAACACCAACAATAACAATAATAACACTAACAACAACAACGTGGAGGCTAAGGCAGTACGGCATCCGAACGGCGGTTCGGTGATCATCGAATCTGTGACGATGCCATCGTTTGCCAATATTCTATTTCCCACCCATCGCAGTGGCAACGAGTGCATTGATCCCGCCCTGTTGCAAAAGAATCCCGAAAACAATGGCAGCAACAGCAGCATAATTGTGCCGACTGTCGAATACCATCAATTGAAGCCACTTGAAGTCAATTCCTCGACTTCCGTTTCCACCAGCAACTTCCTGTCCTCCACAACGGCCCAATTGCTGGACTTTGAGGTGCAGGTGGGCAAGGATGATAGCCACATTAGCACCACTACCACCGCAGGGACAGGCTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGTGCAAGCACAATAGCCACGGCAACGCCCACGACGACCACATCCATGAACAGCACTGCCAATCCGACGAGGAGCTCATTGCACAGTATTGAGGAGCTGGCCGCCAGCTCCTGTGCTCCGCGAGCAGCGTCTCCCAACAGCAACCACACTAGCAGTGCCAGCACCACTCCGCAGCAGCATCCGCATCCGCAGCAGCAGCAGCATCACATGCAGAGCGGCAACCACAGTGGCTCCAATCTCAGCAGCGACGATGAGTCCATGTCCGAGGATGAGTTCGGCCTGGAAATCGACGATAACGGAGGCTACCAGGACACCACCTCCTCACACTCGCAGCAGAGCGGAGGAGGCGGTGGCGGCGGCGGTGGCAACCTGCTCAACGGCAGCTCCGGCGGCAGCTCCGCCGGCGGTGGCTACATGCTGCTTCCCCAGGCCGCAAGCTCCAGTGGCAACAATGCCAATCCGAACGCCGGCCACATGTCCTCCGGTTCCGTGGGCAACGGCGGCGGCGGCAACGGCGGAGCGGGCGGCAACTCCGGTCCGGGCAACCCCATGGGCGGCACGAGCGCCACGCCGGGACATGGCGGCGAGGTGATCGACTTTAAGCACCTGTTCGAGGAGCTGTGTCCCGTGTGCGGCGACAAGGTGAGCGGCTACCACTACGGCCTGCTCACCTGCGAGTCCTGCAAGGGCTTCTTCAAGCGCACCGTGCAGAACAAGAAGGTCTACACCTGCGTGGCGGAGCGGTCGTGCCACATCGACAAGACGCAGCGCAAGCGGTGTCCCTACTGCCGATTCCAGAAGTGCCTTGAAGTGGGCATGAAGCTAGAGGCTGTTCGAGCGGATAGAATGCGTGGTGGACGCAACAAATTCGGACCCATGTACAAACGGGATCGCGCGCGGAAGTTGCAAGTGATGCGGCAGCGGCAGTTGGCGCTGCAAGCGCTGCGCAACTCGATGGGTCCGGACATCAAGCCAACGCCGATCTCGCCGGGCTACCAGCAAGCATATCCAAATATGAACATTAAGCAGGAAATTCAAATACCTCAGGTATCCTCACTCACCCAATCTCCGGACTCGTCGCCCAGCCCCATTGCGATTGCGTTGGGACAGGTGAACGCGAGCACGGGCGGTGTAATAGCCACGCCCATGAGCGCAGGCACAGGCGGCAGTGGGGGCGGAGGTCTGAACGGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNAGCGTCCGGAGGAGGAGGTGGCAATAATGCGGGCGGCGGAGGAGGAGGAAACAATTCCACCGATGGCCTGCATCGCAACGGCGGCAATGGCAACAGCAGTTGCCACGAGGCTGGAATAGGATCTCTGCAGAACACGGCCGACTCGAAATTGTGCTTCGATTCTGGCACACATCCATCGAGCACAGCCGACGCGCTAAACGAGCCATTAAGAGTCTCACCGATGATTCGTGAATTTGTGCAATCGATTGACGATCGGGAATGGCAGACGCAACTGTTTGCCCTGCTGCAGAAGCAAACCTACAACCAGGTGGAAGTGGATCTCTTCGAGCTGATGTGCAAAGTGCTCGACCAGAATTTGTTCTCGCAAGTGGACTGGGCACGGAACACTGTCTTCTTCAAGGATCTGAAGGTTGACGACCAAATGAAGCTGCTGCAGCATTCCTGGTCGGACATGCTTGTTCTGGATCACCTGCATCACCGACTCCATAACGGCCTGCCCGACGAGACGCAACTCAACAATGGTCAGGTCTTTAATCTGATGAGCCTGGGCTTGCTGGGTGTGCCACAGCTGGGCGATTACTTCAACGAGCTGCAGAACAAGCTGCGAGATCTGAAATTCGATATGGGCGACTATGTCTGCATGAAATTCCTAATCCTGTTGAATCCAAGTGTACGGGGTATTGTCAACCGGAAGACCGTCTCCGAGGGACATGATAATGTGCAAGCCGCTTTGCTGGACTACACTCTCACCTGCTATCCGTCAGTCAATGACAAATTCAGAGGGCTAGTTAACATCTTACCGGAAATCCATGCCATGGCCGCTCGCGGCGAGGATCACCTGTACACCAAGCACTGTGCCGGCAGTGCGCCCACCCAAACGCTGCTCATGGAGATGCTGCACGCCAAGCGCAAGGGGTAG
- Protein Sequence
- MDTFNTIDGSQLDGGISLSGLCDRFFVASPNPHSNSNMTLMGTATAATTTTTTNNNNNNNNTNNNNNNTNNNNVEAKAVRHPNGGSVIIESVTMPSFANILFPTHRSGNECIDPALLQKNPENNGSNSSIIVPTVEYHQLKPLEVNSSTSVSTSNFLSSTTAQLLDFEVQVGKDDSHISTTTTAGTGXXXXXXXXXXXXXXXXASTIATATPTTTTSMNSTANPTRSSLHSIEELAASSCAPRAASPNSNHTSSASTTPQQHPHPQQQQHHMQSGNHSGSNLSSDDESMSEDEFGLEIDDNGGYQDTTSSHSQQSGGGGGGGGGNLLNGSSGGSSAGGGYMLLPQAASSSGNNANPNAGHMSSGSVGNGGGGNGGAGGNSGPGNPMGGTSATPGHGGEVIDFKHLFEELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNKKVYTCVAERSCHIDKTQRKRCPYCRFQKCLEVGMKLEAVRADRMRGGRNKFGPMYKRDRARKLQVMRQRQLALQALRNSMGPDIKPTPISPGYQQAYPNMNIKQEIQIPQVSSLTQSPDSSPSPIAIALGQVNASTGGVIATPMSAGTGGSGGGGLNGXXXXXXXXXXXXXXXXXXXXXXXXXASGGGGGNNAGGGGGGNNSTDGLHRNGGNGNSSCHEAGIGSLQNTADSKLCFDSGTHPSSTADALNEPLRVSPMIREFVQSIDDREWQTQLFALLQKQTYNQVEVDLFELMCKVLDQNLFSQVDWARNTVFFKDLKVDDQMKLLQHSWSDMLVLDHLHHRLHNGLPDETQLNNGQVFNLMSLGLLGVPQLGDYFNELQNKLRDLKFDMGDYVCMKFLILLNPSVRGIVNRKTVSEGHDNVQAALLDYTLTCYPSVNDKFRGLVNILPEIHAMAARGEDHLYTKHCAGSAPTQTLLMEMLHAKRKG
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00596709;
- 90% Identity
- iTF_00607842; iTF_00619199; iTF_00619177; iTF_00596709; iTF_00592420; iTF_00596687; iTF_00592441; iTF_00591727; iTF_00591749; iTF_00539709; iTF_00539687;
- 80% Identity
- iTF_00607842;