Dmau012789.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila mauritiana
Gene Symbol
ftz-f1
Assembly
GCA_004382145.1
Location
NC:18252631-18295521[-]

Transcription Factor Domain

TF Family
SF-like
Domain
zf-C4|SF-like
PFAM
AnimalTFDB
TF Group
Zinc-Coordinating Group
Description
The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 5 0.12 8.4e+02 -1.3 3.8 44 95 29 79 6 117 0.58
2 5 2 1.4e+04 -16.4 22.6 65 163 156 256 125 359 0.62
3 5 2 1.4e+04 -7.1 8.1 47 74 331 358 284 384 0.45
4 5 3.5e-19 2.4e-15 56.5 0.4 1 76 566 641 566 671 0.74
5 5 1.5e-69 1e-65 222.4 0.5 157 409 770 1015 751 1016 0.92

Sequence Information

Coding Sequence
ATGGATACCTTCAATGTACCTATGCTGGCggaaagcagcaacaacaactatgCAACAGAAGCTACCAGCAATCATCACCACCTGcaacatcagcatcagcagcaacatccacatcagcagcagcagcagcaactcctAATGCCCCATCATCACAAGGATCAAATGCTGGCAGCGGGCAGTTCGCCCATGCTGCCATTCTATTCACACTTGCAGTTGCAACAGAAGgatgcaactgcagcaataggacctgcagcagctgcagcggcagctgTTGAGGCGGCAACAACATCGGCAAATGCCGACAACTTCAGTTCATTGCAAACGATCGATGGCAGTCAACTGGATGGAGGCATCTCCTTGAGCGGCTTGTGCGATCGTTTCTTTGTGGCCAGTCCAAATCCCCACAGCAATAGCAATATGACTCTAATGGGCACtgcgacagcagcaacaactaccactaccaacaacaataataataacaacaataataacactaacaataacaataacaacgacGTGGAGGCTAAGACAGTGAGGCCATCGAACGGCAATTCGGTGATCATCGAATCTGTGACGATGCCATCGTTTGCCAATATTCTATTTCCCACCCATCGCAGCGCCAACGAGTGCATTGATCCCGCCCTGTTGCAAAAGAATCCCCAAAACAATGgcaccaacaacaacgaatATCATCAATTGAAACCACTTGAAGTCAATTCGTCGACTTCCGTTTCCACCAGCAACTTCCTGTCCTCCACAACGGCCCAATTGTTGGACTTTGAGGTGCAGGTGGGCAAGGATGATAGCCACATTAGCACCACTACGACCACAGGGCAAGGTTCTGGAACGGGATCGGCATCGGGATCAGGATCGAGTGCAAGTACAATGGGCACTGCAACGCCCACAACGACAACATCCATGAGCAACACTGCCAATCCGACGAGGAGCTCATTGCACAGTATTGAAGAGCTGGCCGCCAGTTCCTGTGCCCCGAGAGCAGCGTCTCCCAACAGCAACCACACTAGCAGTGCCAGCACCactccgcagcagcagcagcagcatcatcacaTGCAAAGCGGCAACCACAGTGGCTCCAATCTCAGCAGCGACGATGAGTCCATGTCCGAGGATGAGTTCGGTCTGGAAATCGACGATAACGGAGGCTACCAGGACACCACCTCCTCGCACTCGCAGCAGagcggaggaggcggtggcggcggcggtggcaatCTGCTAAACGGCAGCTCCGGCGGCAGCTCCGCCGGCGGTGGCTACATGCTGCTCCCGCAGGCGGCCAGCTCCAGTGGCAACAATGGCAACCCGAATGCCGGCCACATGTCCTCCGGTTCCGTGGGCAACGGCAGCGGAGGCGCTGGCAACGGCGGAGCGGGCGGCAACTCCGGTCCCGGCAATCCCATGGGCGGCACAAGCGCCACGCCGGGACACGGCGGCGAGGTGATCGACTTTAAGCACCTGTTCGAGGAGCTTTGTCCCGTGTGCGGCGACAAGGTGAGCGGCTACCACTACGGCCTGCTCACGTGCGAGTCCTGCAAGGGCTTCTTCAAGCGCACCGTGCAGAACAAGAAGGTCTACACCTGCGTGGCGGAGCGGTCGTGCCACATCGacaagacgcagcgcaagcgGTGTCCCTACTGCCGATTCCAGAAGTGCCTCGAGGTGGGCATGAAGCTAGAGGCTGTTCGAGCGGATAGAATGCGTGGTGGACGCAACAAATTCGGACCCATGTACAAACGAGATCGCGCGCGGAAGTTGCAAGTGATGCGGCAGCGGCAGTTGGCGCTGCAAGCGCTGCGCAACTCGATGGGTCCGGACATCAAGCCAACGCCGATCTCGCCGGGCTACCAGCAAGCATATCCAAATATGAACATTAAGCAGGAAATTCAAATACCTCAGGTATCCTCACTCACCCAATCTCCGGACTCGTCGCCCAGCCCCATAGCGATTGCGTTGGGACAGGTGAACGCGAGCACGGGCGGTGTAATAGCCACGCCCATGAACGCCGGCACTGGCGGCAGTGGGGGCGGTGGTCTGAACGGACCGAGTTCCGTGGGCAACGGCaatagcagcaacggcagcagcaacggcaacaacaacagcagcacgGGCAACGGAGCGtccggaggaggaggtggcaATAATGCGggcggtggaggaggaggaaccAATTCCACCGATGGCCTGCATCGCAACGGCGGCAATGGCAACAGCAGTTGCCACGAGGCTGGAATAGGATCTCTGCAGAATACGGCCGACTCGAAATTGTGCTTCGATTCTGGCACACATCCATCGAGCACAGCCGACGCGCTAATCGAGCCATTAAGAGTCTCACCGATGATTCGTGAATTTGTGCAATCGATTGACGATCGGGAATGGCAGACGCAACTGTTTGCCCTGCTGCAGAAGCAAACCTACAACCAGGTGGAAGTGGATCTCTTCGAGCTGATGTGCAAAGTGCTCGACCAGAATTTGTTCTCGCAAGTAGACTGGGCACGGAACACCGTCTTCTTCAAGGATCTGAAGgTCGACGACCAAATGAAGCTGCTGCAGCATTCTTGGTCGGACATGCTTGTTCTGGATCACCTGCATCATCGAATCCATAACGGCCTGCCCGACGAGACGCAACTCAACAATGGTCAGGTGTTCAATCTGATGAGTCTGGGTTTGTTGGGAGTGCCACAGCTGGGCGATTACTTCAACGAGCTGCAGAACAAGCTGCAGGACCTGAAATTCGATATGGGCGACTATGTCTGCATGAAATTCCTAATCCTGTTGAATCCAAgTGTACGGGGTATTGTCAACCGGAAGACCGTCTCCGAGGGACATGATAATGTGCAAGCCGCTTTGCTGGACTACACCCTCACCTGCTATCCGTCAGTGAATGACAAATTCAGAGGGCTAGTTAACATCTTACCGGAAATCCATGCCATGGCCGCTCGCGGCGAGGATCACCTGTACACCAAGCACTGTGCCGGCAGTGCGCCCACCCAAACGCTGCTCATGGAGATGCTGCACGCCAAGCGCAAGGGGTAG
Protein Sequence
MDTFNVPMLAESSNNNYATEATSNHHHLQHQHQQQHPHQQQQQQLLMPHHHKDQMLAAGSSPMLPFYSHLQLQQKDATAAIGPAAAAAAAVEAATTSANADNFSSLQTIDGSQLDGGISLSGLCDRFFVASPNPHSNSNMTLMGTATAATTTTTNNNNNNNNNNTNNNNNNDVEAKTVRPSNGNSVIIESVTMPSFANILFPTHRSANECIDPALLQKNPQNNGTNNNEYHQLKPLEVNSSTSVSTSNFLSSTTAQLLDFEVQVGKDDSHISTTTTTGQGSGTGSASGSGSSASTMGTATPTTTTSMSNTANPTRSSLHSIEELAASSCAPRAASPNSNHTSSASTTPQQQQQHHHMQSGNHSGSNLSSDDESMSEDEFGLEIDDNGGYQDTTSSHSQQSGGGGGGGGGNLLNGSSGGSSAGGGYMLLPQAASSSGNNGNPNAGHMSSGSVGNGSGGAGNGGAGGNSGPGNPMGGTSATPGHGGEVIDFKHLFEELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNKKVYTCVAERSCHIDKTQRKRCPYCRFQKCLEVGMKLEAVRADRMRGGRNKFGPMYKRDRARKLQVMRQRQLALQALRNSMGPDIKPTPISPGYQQAYPNMNIKQEIQIPQVSSLTQSPDSSPSPIAIALGQVNASTGGVIATPMNAGTGGSGGGGLNGPSSVGNGNSSNGSSNGNNNSSTGNGASGGGGGNNAGGGGGGTNSTDGLHRNGGNGNSSCHEAGIGSLQNTADSKLCFDSGTHPSSTADALIEPLRVSPMIREFVQSIDDREWQTQLFALLQKQTYNQVEVDLFELMCKVLDQNLFSQVDWARNTVFFKDLKVDDQMKLLQHSWSDMLVLDHLHHRIHNGLPDETQLNNGQVFNLMSLGLLGVPQLGDYFNELQNKLQDLKFDMGDYVCMKFLILLNPSVRGIVNRKTVSEGHDNVQAALLDYTLTCYPSVNDKFRGLVNILPEIHAMAARGEDHLYTKHCAGSAPTQTLLMEMLHAKRKG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00596709;
90% Identity
iTF_00607819;
80% Identity
iTF_00539709;