Basic Information

Insect: Drosophila tanythrix
Gene Symbol: zfh1
Assembly: GCA_035043275.1
Location: JAWNNC010000509.1:899716-905466[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 3e-05 0.0021 18.5 1.0 1 23 152 174 152 174 0.97

2 15 0.0011 0.076 13.6 0.9 3 23 182 202 180 202 0.93

3 15 9.3e-05 0.0065 17.0 0.1 1 23 371 393 371 393 0.98

4 15 0.00035 0.024 15.2 0.9 1 23 399 421 399 421 0.98

5 15 0.00012 0.0087 16.6 2.3 1 23 453 476 453 476 0.94

6 15 0.012 0.86 10.3 3.0 1 23 522 544 522 544 0.94

7 15 0.0045 0.31 11.7 0.4 1 23 550 573 550 573 0.98

8 15 0.03 2.1 9.1 0.4 3 19 582 598 581 599 0.95

9 15 0.00018 0.012 16.1 5.6 1 23 608 630 608 630 0.97

10 15 0.046 3.2 8.5 1.2 2 23 636 657 635 657 0.96

11 15 1e-05 0.00072 20.0 1.0 1 23 666 688 666 688 0.98

12 15 0.0012 0.082 13.5 0.1 3 23 696 716 694 716 0.97

13 15 6.3e-05 0.0044 17.5 0.5 1 23 722 744 722 745 0.95

14 15 0.053 3.7 8.3 0.4 1 23 755 777 755 777 0.97

15 15 0.0018 0.13 13.0 1.0 1 23 1282 1304 1282 1304 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	3e-05	0.0021	18.5	1.0	1	23	152	174	152	174	0.97
2	15	0.0011	0.076	13.6	0.9	3	23	182	202	180	202	0.93
3	15	9.3e-05	0.0065	17.0	0.1	1	23	371	393	371	393	0.98
4	15	0.00035	0.024	15.2	0.9	1	23	399	421	399	421	0.98
5	15	0.00012	0.0087	16.6	2.3	1	23	453	476	453	476	0.94
6	15	0.012	0.86	10.3	3.0	1	23	522	544	522	544	0.94
7	15	0.0045	0.31	11.7	0.4	1	23	550	573	550	573	0.98
8	15	0.03	2.1	9.1	0.4	3	19	582	598	581	599	0.95
9	15	0.00018	0.012	16.1	5.6	1	23	608	630	608	630	0.97
10	15	0.046	3.2	8.5	1.2	2	23	636	657	635	657	0.96
11	15	1e-05	0.00072	20.0	1.0	1	23	666	688	666	688	0.98
12	15	0.0012	0.082	13.5	0.1	3	23	696	716	694	716	0.97
13	15	6.3e-05	0.0044	17.5	0.5	1	23	722	744	722	745	0.95
14	15	0.053	3.7	8.3	0.4	1	23	755	777	755	777	0.97
15	15	0.0018	0.13	13.0	1.0	1	23	1282	1304	1282	1304	0.98

Sequence Information

Coding Sequence: ATGAACAATCCGGACTATGGCGGCATCCAGTGGATACAGCAGGAAAGCAGCCCCGTCGTCGACGACAGTGAAACAGAGATGACAGCAGCCTATTTGGTCAACGCTGCCGCCAATGGAAGCATTTCCAACGATGACGAGCTCGATCATATAGCAGCCGAGAATCTCATCTTTATGGCACGCGACCGCCAACTGAGCGAAATCATCGCCGCAAATGAGGCAAATGGCGGCAGCACTACAGTGCTAATCACGGAAAGAGACGGAAATAACGGAGTGGAATACGCCGAGTCTTTTGACGATGATGCCCAAGTCGTCACCGAGGAGATCATCACGGATGATTGGGTCCAGCATCAGGGCGCAGAGCGtgTGGAAATTGCAGCAGAGCAAATTGCTGGCAACGGCAGCTCCCAGGAGCTGTTGGACATGCAACAGAATGAATATATGGCGATGCGCCCATATCCCTGTGACTTTTGCAGTCGACGCTTTCGCAAGAAGGCCAGCCTCAACAATCATATGCTGGCGCATCAGAATGATCGTCCCCATCTCTGCAAACTGTGCGGGGCGCGATTCTCGCGACGTGCGGAGCTCATCAGTCACTTCCAGGCTCATGCGGAGGCCCAGGTGGCCGCCGATGAAGAGGCAGCTGCGGCAGCCATTAAATTtgagccacaacagcagctgcaaacgctgcaacagcagcagcagcagcagcgacaaattGATGATCATTTCTATGAGCAGGAATGGCCGCTGTAtcaggaacaggaacaggagcagctggagcagatcgaggagcagcagcaacagcagctggagcagcatcagcagctgttgcaacaaTCGGTTGCACCACCAACCGCTGCTCGTGGACGTATCAGTCGATTGAAACTCAAGGAGGAGAGTTCCCAATATATTGTGATTGCCTCCGATAAACCGGAGACGGAGTTGCCGCCTCAATACATGCATTGCGATGCGAATTGCGATCAATCACTTgccaccaacagcagccaagTCCAATCAACATCATCCAATgatgttgcaactgctgctgctgctgatggggCAGAGGGGCAGGCAACGCTCCGCTTTCCCGTGCTCGACGAGAGCAAACCGTTCGTCTGTCAGCAGTGCGGATTGGCCTTTGCCCGCGAGAAGGCGCTCCTCTCCCACATCAAGAATCATCGCGTGGATTCGCCTTTTGAATGCAATCAGTGCCAGGAGATGTTCTGGGACAATTACAGTCTGCAGGAGCATCAGAAGACGCATCAGTTCGAGGAGAGCAATTCGGAATATGATCCCGCATCGGCGGGCGAGGAGGATACGGCGAGTGAATCGGAAGCGGAACAGCTTTACGGTGTTTTCTACTGCGGCGAATGCGGCATCTCCTTTCACCGCCAGGATTTGTTGCGGCgccacagcaaacagcagcacagcaagcagctggctgcaacaacagctggtggcaacaacaacaacagtgtggcaactgcaacagcaacggaTGCAATGGGTACTGCAGATGGAACCGCAACTGATGCCGATGCTGATGATTCCAAAGATGCGACACATTGTTGCCACACGTGCGGCAAATCGTTTCCCAGCGTACTCAAACTGCTCGCCCATGCCGAAATCCACAAACGCTTCCCGCCATTCAAATGTGTGCTGTGCGGAGTCAGCTTCTACGAGGAGCAGGCGATAAAGCGGCACCTGAACACGCGGCATCCGAACGAGCTGAAGCCCAAttcgtgtgtgttgtgcggcAAGGAGTGTCGCGATCGGAAGGCGCTGATCAAACATGCGTGGGATCATTCGCGGGAGAAGTGCCACTCGTGCTCCAAGTGTGGCAAGAATTTCCACAACAAGGCGCGCCTGAAGCGACACATGGCATCGCATCGCGACAAGTCCGTCGTGTGCGAAGTGTGCCACGAGGAGTTCCCCGATGGACGCACTTTGTCCAATCATCGGCATTCCCACAGCACAACGTCGCCGGGCAAACTGTTTCCCTGCCACGAGTGTGGCAAGACTTTTGGGTCACGCAGCTCGCAACAGATTCATGTGCGCATCCACACGGGTGAAAGGCCCTACGGTTGTCGCTACTGCTGGAAGGCCTTCGCCGACGGCGGTACTCTCCGCAAACACGAACGCATCCATACGGGCGAGAAGCCCTATGCGTGCTCCGTCTGCCCGCGTGCCTTCAATCAGCGAGTCGTCTTGCGGGAACACATCCGGTCGCATCATTCCGGTCTGGATGCGGCACGTGGCACGTATCATTGCACGGTGTGCTCGGCGGATTTGAGCTCATCGAATGACCTCATCCAGCATCTCATCCAGCACAGTGATACGAACACAGCCAAACAGCGACAGCCAATTACTGGCCCACGTAAATACAAACGTCGCCGGAAACTGCAGCCGCATGAGATTGCGCACATGCGCGCCGAGCACAAGGCTGGCGGCGGCGATGGCGAGGCTggcgaagaggaggaggattACGCCAGCGACTTGGACTACTGCCATCTGGATGTAGAGAATGTGGATGAACTGCTGCAGGAGGCAACGGCGGAGCCACCATCACCgaccaaaaaagcaaaacgcaAACGCAAAGCGCCAATTAAATCCGGTGATGAGCAAAGATTGTGGGATGAGAAATTCGTGCAGCAGGCGAGCAATGGGAATAGCGATGAGGCCTACAAGAGTTTCTTCCAGATGGACTCAATGGTCGTGGTCAATGATCAAACTTTGCAGCCCGTTGATACTGGTGTTGCCTCGACCAAGTTGCAGCAGGCGGAGATTAAGGAGCAAACACTGAAGACAGGCAATCGCAGTAGCAAAAGAAGGGCAGGTAAAGCTgggggaggaggagcaggagctgctgctacgcctgctactgctgctccaCGTCCCCGGATGATACACACTGCCAAGTCGCAGCCGACAACGGCAAGGAAATCCCGCACAAGGAGTTATCTCACACGCACCAGCAccaatgagcagcagcagggggGAGGAGCAAGTGGAGGAAGCCTCATCAAATCCCGAATTGTGGATGACTACGAGATTATCTCCCCGGCCACACAGCCACCCAATCAGATCAGCTCCAGTCCGCTGCACATCaaacaggagcaggaacatcaacagcatcatcatcatcaccatcatcatcagcagcagcagcagagagtACAACTGCTCTTCGATGACAGCCATCTGCTCATCGATGCGGGCCTGTTGCGTGAGAAGACCTACGAGAAATATAATCCCAGCATTGTCCAAGATCTCGAAGAGATTTTGCGTAGTCCCCCGAAGCATGAGCGGAACGATCGACGGCTGCGCTTCACCAGCGAATCGTCGACGACGCCACAATTTCTGCCCGGCGAGGAGGAGGAACAGCATCTCATCAAGATCGAGCCCACGTCGCCGGATCTCCGCGAAATGGTCGAGAGCCAGCAGCCAGCGGCACTGCCCACATCCTCCTCCGCCTGCTCAACGGCAGCACGTACTTCCCGCCACCTGCGACATCTGACTGCCAATGGTTCCAGTTCCATTTCCACTCCCACATCCAGTTCCAGTGGCGCTCCCAGTACGCGATCTGCTTCCAGGCGCAATGCCAGCAAACAGCTTTCTAAGAAATCCActtccaacagcaacaaaggcaaCGCATCATCGTCTTATCTCAGCTATGGCGTCGATTCCTATAATGTGGGCGTCGCAGCCAGTGCCAATAGCTCCTCGGATGTCAGTTCCGgtttcttttccatttccgAGGTCGTCTCGGCGGCGGATGCAGCCGATGCAGCTGCgaaggcggcggcggcagcagccagcaaaacGCAGCGAAGAACGCGCTGCTTTGAGTGCGAAATGTGCTCGTCCTATTTCACAGATCGCGCCCAACTGCTGgaacacatgcacatacacatctAG
Protein Sequence: MNNPDYGGIQWIQQESSPVVDDSETEMTAAYLVNAAANGSISNDDELDHIAAENLIFMARDRQLSEIIAANEANGGSTTVLITERDGNNGVEYAESFDDDAQVVTEEIITDDWVQHQGAERVEIAAEQIAGNGSSQELLDMQQNEYMAMRPYPCDFCSRRFRKKASLNNHMLAHQNDRPHLCKLCGARFSRRAELISHFQAHAEAQVAADEEAAAAAIKFEPQQQLQTLQQQQQQQRQIDDHFYEQEWPLYQEQEQEQLEQIEEQQQQQLEQHQQLLQQSVAPPTAARGRISRLKLKEESSQYIVIASDKPETELPPQYMHCDANCDQSLATNSSQVQSTSSNDVATAAAADGAEGQATLRFPVLDESKPFVCQQCGLAFAREKALLSHIKNHRVDSPFECNQCQEMFWDNYSLQEHQKTHQFEESNSEYDPASAGEEDTASESEAEQLYGVFYCGECGISFHRQDLLRRHSKQQHSKQLAATTAGGNNNNSVATATATDAMGTADGTATDADADDSKDATHCCHTCGKSFPSVLKLLAHAEIHKRFPPFKCVLCGVSFYEEQAIKRHLNTRHPNELKPNSCVLCGKECRDRKALIKHAWDHSREKCHSCSKCGKNFHNKARLKRHMASHRDKSVVCEVCHEEFPDGRTLSNHRHSHSTTSPGKLFPCHECGKTFGSRSSQQIHVRIHTGERPYGCRYCWKAFADGGTLRKHERIHTGEKPYACSVCPRAFNQRVVLREHIRSHHSGLDAARGTYHCTVCSADLSSSNDLIQHLIQHSDTNTAKQRQPITGPRKYKRRRKLQPHEIAHMRAEHKAGGGDGEAGEEEEDYASDLDYCHLDVENVDELLQEATAEPPSPTKKAKRKRKAPIKSGDEQRLWDEKFVQQASNGNSDEAYKSFFQMDSMVVVNDQTLQPVDTGVASTKLQQAEIKEQTLKTGNRSSKRRAGKAGGGGAGAAATPATAAPRPRMIHTAKSQPTTARKSRTRSYLTRTSTNEQQQGGGASGGSLIKSRIVDDYEIISPATQPPNQISSSPLHIKQEQEHQQHHHHHHHHQQQQQRVQLLFDDSHLLIDAGLLREKTYEKYNPSIVQDLEEILRSPPKHERNDRRLRFTSESSTTPQFLPGEEEEQHLIKIEPTSPDLREMVESQQPAALPTSSSACSTAARTSRHLRHLTANGSSSISTPTSSSSGAPSTRSASRRNASKQLSKKSTSNSNKGNASSSYLSYGVDSYNVGVAASANSSSDVSSGFFSISEVVSAADAADAAAKAAAAAASKTQRRTRCFECEMCSSYFTDRAQLLEHMHIHI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00542584;
90% Identity: iTF_00499722;
80% Identity: -